• Title/Summary/Keyword: remission

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Biological Therapy for Inflammatory Bowel Disease in Children

  • Na, So-Young;Shim, Jung-Ok
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.15 no.1
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    • pp.13-18
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    • 2012
  • The pathogenesis of inflammatory bowel diseases is not very well understood; it is currently thought to be caused by the interaction between genetic factors, environmental factors, intestinal microbes, and immune factors. Biological agents such as anti-tumor necrosis factor (anti-TNF) are widely being used as therapeutic agents. Infliximab, a chimeric monoclonal IgG1 antibody against tumor necrosis factor, has been demonstrated to have an effect in the induction and maintenance of remission in Crohn's disease in children. The effects of biological agents, typified by anti-TNFs, in inflammatory bowel disease in children; the recent concern on the administration of biological agents in combination with immunomodulators; and 'Top-down' therapy are some of the topics covered in this review.

Pure Red Cell Aplasia Associated with Good Syndrome

  • Okui, Masayuki;Yamamichi, Takashi;Asakawa, Ayaka;Harada, Masahiko;Horio, Hirotoshi
    • Journal of Chest Surgery
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    • v.50 no.2
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    • pp.119-122
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    • 2017
  • Pure red cell aplasia (PRCA) and hypogammaglobulinemia are paraneoplastic syndromes that are rarer than myasthenia gravis in patients with thymoma. Good syndrome coexisting with PRCA is an extremely rare pathology. We report the case of a 50-year-old man with thymoma and PRCA associated with Good syndrome who achieved complete PRCA remission after thymectomy and postoperative immunosuppressive therapy, and provide a review of the pertinent literature.

A Case of Leptomeningeal Metastasis Presented with Thoracolumbar Radiculopathy (흉요추 신경근병증으로 발현된 수막암종증 1예)

  • Min, Ji-Won;Lee, Ji-Hyun;Kim, Min-Jung;Yoo, Bong-Goo
    • Annals of Clinical Neurophysiology
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    • v.7 no.1
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    • pp.22-24
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    • 2005
  • We report a case of thoracolumbar radiculopathy presented with first symptom of leptomeningeal metastasis. A 65-year old man with non-Hodgkins lymphoma with complete remission was referred for further investigation of dull pain and numbness of right lower quadrant of abdomen. Electromyogram revealed right thoracolumbar radiculopathy. After two weeks, he complained severe continuous bilateral frontal dull headache. An examination of the cerebrospinal fluid revealed malignant lymphoid cells. We would like to emphasize that radiculopathy sometimes presents with first symptom of leptomeningeal metastasis.

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A Case Report of Systemic Type Juvenile Idiopathic Arthritis with Night Fever (야간 발열을 동반하는 전신형(Systemic type) 소아기 류마티스 관절염(Juvenile Idiopathic Arthritis; JIA) 환아 증례보고)

  • Yoo, Chang-Kil;Lee, Yun-Ju
    • The Journal of Pediatrics of Korean Medicine
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    • v.24 no.3
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    • pp.68-75
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    • 2010
  • Objectives: This study is to report a case that has an effective result to systemic type juvenile idiopathic arthritis patient with an oriental medicine treatment. Methods: We treated the patient with an oriental medicine and tapered down with the western medicine. We followed up the laboratory blood tests every two or three months and through telephone at least six days in a week. Results: The symptoms of systemic type juvenile idiopathic arthritis were vanished and the patient maintains his condition with oriental medicine treatment after discontinued all Disease-Modifying Antirheumatic Drugs(DMARDs). His ESR, CRP levels and other blood test results were back to normal range. Now he is in clinical remission status. Conclusions: According to the result, the oriental medicine treatment is considered to be effective on the systemic juvenile idiopathic arthritis and further studies will be needed with more cases.

Traditional topical herbal therapies in psoriasis

  • Keseroglu, Havva Ozge;Gonul, Muzeyyen
    • CELLMED
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    • v.4 no.4
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    • pp.23.1-23.8
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    • 2014
  • Psoriasis is a common, chronic, recurrent, immune-mediated inflammatory disorder of skin. Although conventional topical and systemic therapies yield remission for a while, they carry a risk of many side effects that limit the long term use of these agents and the disease recurs generally in a short period of time after cessation of therapy. An increasing number of psoriatic patients are using herbal products as a treatment to control their disease with less side effects. Clinicians should be aware of plants used in psoriasis and side effects related with them. The aim of this article is to review the different herbs used in psoriasis treatment.

Life Experience of Patients suffering from Crohn's Disease (크론병 환자의 삶의 경험)

  • Yoo, Yang-Sook;Lee, Eun-Ju;Cho, Ok-Hee
    • Journal of Korean Academy of Nursing
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    • v.43 no.3
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    • pp.409-419
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    • 2013
  • Purpose: The purpose of this study was to describe and explore the experience process of life of patients with Crohn's disease. Methods: Using a grounded theory methodology, 24 interviews were performed with 7 men and 5 women, 17-47 years of age, suffering from Crohn's disease. Results: 'Tuning of two conflicting lives' was identified as the core category, and 5 subcategories were identified and they were integrated into the core category. The identified outcomes were 'Living a withdrawn life', 'coping flexibly', 'drifting with tangled emotions' and 'maintaining long-term remission'. Conclusion: When caring for these patients, it is important to identify needs, allow patients to express what they want at that moment and support them in maintaining a daily life that can be perceived as normal.

A Case Report of Chronic Paranasal Sinusitis Who Complains Postnasal Drip (後鼻漏를 主訴로 한 慢性 副鼻洞炎 患者의 治驗 1例)

  • Kim, Chang-hwan;Sun, Young-jae;Lim, Woong-kyoung;Kim, Hyun-gi
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.16 no.2
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    • pp.244-248
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    • 2003
  • Paranasal sinusitis is a common disease in the otorhinolaryngology area. It is the change of inflammation at the mucous membrane which surrounds paranasal sinus. Chronic paranasal sinusitis is a chronic inflammation disease with purulent, mucous rhinorrhea, postnasal drip and cough. The attacked period continues above three months and it repeats exacerbation and remission. We diagnosed and treated an outpatient who complains postnasal drip of chronic paranasal drip of chronic paranasal sinusitis based on the Oriental medical theories and had good result.

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A Torticollis Case Managed by Balance Appliance of FCST for the Meridian and Neurologic Balance (FCST의 음양균형장치를 활용한 후천성 사경증 증례보고)

  • Yin, Chang-Shik;Koh, Gi-Wan;Sohn, Kyung-Seok;Lee, Jong-Jin;Sohn, Il-Hoon;Lee, Young-Jun
    • Korean Journal of Acupuncture
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    • v.23 no.1
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    • pp.119-123
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    • 2006
  • Objectives : Therapeutic effect of Balance Appliance of functional cerebrospinal therapy (FCST) for meridian and neurologic yinyang balance was observed in a refractory torticollis case. Methods : A post-traumatic severe torticollis case with 18 years of duration was managed by the Balance Appliance on temporomandibular joint (TMJ), combined with acupuncture and manual medicine. Results : Assessment was made by self assessment of subjective symptoms and clinical observacon. The patient reported over-90% remission and returned to ordinary daily life after 20months of therapy, which effect was reported to maintain for 9 months. Conclusions : An impressive effect was observed and further clinical and biological research on FCST is expected.

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Stellate Ganglion Block for Shoulder Hand Syndrome following Hemiplegia (편마비후 발생한 견수 증후군에 대한 성상신경절차단)

  • Yoon, Duck-Mi;Oh, Hung-Kun;Yoo, Eun-Sook;Chung, So-Young
    • The Korean Journal of Pain
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    • v.6 no.2
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    • pp.255-257
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    • 1993
  • Shoulder Hand Syndrome is used to describe painful disabilities of the upper extremity due to disturbances of sympathetic nerve supply. A 72 year old male developed hemiplegia on left side on the 5 days after open heart surgery of aortic valve replacement. Three months later, the patient complained of severe pain in the left upper extremity involving shoulder. The left hand showed swelling and flaccid paralysis. Thereafter the left stellate garglion block with 10 ml of l% lidocaine produced prompt pain relief. Thereafter the patient received 94 stellate ganglion block during 7 months which produced permanent remission of pain throughout a 1 year follow period. We recommand sympathetic block for of Shoulder Hand Syndrome following hemiplegia.

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Exceptional response to radiotherapy in unresectable pleuropulmonary blastoma of a child

  • Kim, Jae Sik;Lee, Joo Ho
    • Radiation Oncology Journal
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    • v.38 no.2
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    • pp.148-150
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    • 2020
  • Pleuropulmonary blastoma (PPB) is a rare intrathoracic neoplasm in children. Although surgery with or without chemotherapy mainly conducted, the response of radiotherapy (RT) has not been evaluated yet. For unresectable tumor, RT might be considered as one option to decrease tumor extent to relieve obstructing symptoms or to facilitate successive treatment. We report one child in whom PPB with DICER1 mutation recurred after surgery and lead to respiratory distress. She emergently received palliative RT with a relatively low dose (20 Gy), and symptoms sufficiently relieved. Even she showed an 84.3% reduction in diameter and maintained the remission status for 1 year. These might reflect possible radiosensitivity of PPB, and further investigations of RT might be necessary for unresectable PPB.