• Asian Journal of Innovation and Policy
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• v.8 no.3
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• pp.325-342
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• 2019

Gendered innovation in Science, Technology and Innovation, which seeks better science for both men and women by integrating sex and gender analysis, has become an important issue in the entire process of STI, as initiated by the European Commission, Canadian Institutes of Health Research in Canada and the National Institutes of Health in the United States. Korea has also attempted to reflect gendered innovations in Science and Technology as a critical factor in the 3rd and 4th National Plan, followed by the Act on Women Scientists and Engineers (2002). Against this background, the aim of this study is to prioritize the policy instruments regarding gendered innovation in Research and Development. Through the Focus Group Interview (FGI) and the Analytic Hierarchy Process (AHP), this study attempts to set the priority among selected criteria, various types of policy instruments, and the applied research development area. As a result, this study shows the preparation of the relevant legal and institutional mechanisms for the full introduction of gendered innovation in S&T, and the importance of various policy instruments for S&T innovation in the fields of planning, budgeting, managing national R&D projects, evaluating and impact assessment, etc., being derived in a systematic way to ensure their effectiveness.

• Clinical and Experimental Pediatrics
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• v.56 no.7
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• pp.271-274
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• 2013

Brain insults, including neurotrauma, infection, and perinatal injuries such as hypoxic ischemic encephalopathy, generate inflammation in the brain. These inflammatory cascades induce a wide spectrum of cytokines, which can cause neuron degeneration, have neurotoxic effects on brain tissue, and lead to the development of seizures, even if they are subclinical and occur at birth. Cytokines are secreted by the glial cells of the central nervous system and they function as immune system mediators. Cytokines can be proinflammatory or anti-inflammatory. Interleukin (IL)-$1{\beta}$ and IL-8 are proinflammatory cytokines that activate additional cytokine cascades and increase seizure susceptibility and organ damage, whereas IL-1 receptor antagonist and IL-10 act as anti-inflammatory cytokines that have protective and anticonvulsant effects. Therefore, the immune system and its associated inflammatory reactions appear to play an important role in brain damage. Whether cytokine release is relevant for the processes of epileptogenesis and antiepileptogenesis, and whether epileptogenesis could be prevented by immunomodulatory treatment should be addressed in future clinical studies. Furthermore, early detection of brain damage and early intervention are essential for the prevention of disease progression and further neurological complications. Therefore, cytokines might be useful as biomarkers for earlier detection of brain damage in high-risk infants.

• Biomolecules & Therapeutics
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• v.25 no.1
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• pp.12-25
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• 2017

G protein-coupled receptors (GPCRs) are a family of cell-surface proteins that play critical roles in regulating a variety of pathophysiological processes and thus are targeted by almost a third of currently available therapeutics. It was originally thought that GPCRs convert extracellular stimuli into intracellular signals through activating G proteins, whereas ${\beta}$-arrestins have important roles in internalization and desensitization of the receptor. Over the past decade, several novel functional aspects of ${\beta}$-arrestins in regulating GPCR signaling have been discovered. These previously unanticipated roles of ${\beta}$-arrestins to act as signal transducers and mediators of G protein-independent signaling have led to the concept of biased agonism. Biased GPCR ligands are able to engage with their target receptors in a manner that preferentially activates only G protein- or ${\beta}$-arrestin-mediated downstream signaling. This offers the potential for next generation drugs with high selectivity to therapeutically relevant GPCR signaling pathways. In this review, we provide a summary of the recent studies highlighting G protein- or ${\beta}$-arrestin-biased GPCR signaling and the effects of biased ligands on disease pathogenesis and regulation.

• Journal of the Korean Home Economics Association
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• v.26 no.1
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• pp.137-149
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• 1988

In this study a series of approaches have been made to find out how complaining behavior would show according to the conviction in the locus of control as to where the general contents dissatisfied by consumers and the dissatisfied consumers would place the responsibility for the consequence of behavior and to test the difference of complaining behavior pursuant to demographic variables and the complaining behavior. The results of this study are described as follows: 1. The consumers have largely attributed the locus of responsibility for their dissatisfaction following the purchase of refrigerators to the relevant manufacturers, advertizers, consumer(herself) and distributors, and as for the dissatisfaction by an attribute of refrigerator, a high level of dissatisfaction was revealed on the price and items of properties. 2. There was no difference in the complaining behavior of consumers pursuant to the demographic features. 3. It was revealed that there wee many consumers, among those respondents to questionnaires, who have actually shown their complaing behavior, while most of them would act inthe form o private behavior, because the cases of acting positive way of public behavior, even though they were apt to show complaining behavior, appears to be extremely rare. 4. A significant difference was shown in the complaing behavior pursuant to the conviction in the locus of control.

• Journal of Arbitration Studies
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• v.17 no.3
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• pp.101-119
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• 2007

Arbitration is contractual by nature. One cannot be required to submit to arbitration any dispute which he has not agreed to so submit. As commercial transactions become increasingly complex, involving multiple parties and numerous contracts for a single transaction, however, limiting the parties who are subject to arbitration to only those who have signed a contract containing an arbitration clause would frustrate the purpose of such arbitration clause and might lead to injustice among the relevant parties. Therefore, U.S. courts have recognized a number of theories under which non-signatories may be bound to the arbitration agreement of others: (1) incorporation by reference; (2) assumption; (3) agency; (4) veil-piercing/alter ego; and (5) estoppel. Incorporation by reference and veil-piercing theories have already been recognized by Korean courts. Agency theory and estoppel theory are not recognizable under Korean law. However, the same or similar result may be achieved by applying the third party beneficiary theory or assumption by third party theory. Although a couple of Supreme Court cases appear to be at odds with the assumption theory, on the basis of the recent amendments to the Arbitration Act, such court precedents can be and should be reversed.

• Child Health Nursing Research
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• v.23 no.1
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• pp.19-27
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• 2017

Purpose: The purpose of this study was to analyze addiction prevention related content shown in middle school text books. Methods: Using a combination of the terms "addiction", "drug", "medicine", "personal preference", "smoking", "drinking", "sex", "misuse" or "abuse" as key words, the researchers screened the table of contents of 23 randomly selected middle school textbooks from the 2009 curriculum. Finally 13 textbooks (physical education=10, health=3) were selected for this study, and analyzed using Krippendorff's contents analysis. Results: Through indepth discussion and investigation of the relevant textbooks, content related to addiction prevention included material addiction (77.8%) and behavioral addiction (22.2%). The construction of addiction prevention in middle school textbooks included understanding addiction, rejection of peer temptation, and empowerment of self-control. Conclusion: When developing an intervention for addiction prevention that targets middle school students, education with accurate addiction information must be considered so that the students have the correct knowledge about addiction and addiction prevention. Additionally, the ability to reject peer temptation when invited to act upon related addiction behaviors should be treated seriously. The empowerment of self-control is also important, and can be promoted through strengthening self-regulation competence.

• Journal of radiological science and technology
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• v.17 no.1
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• pp.87-96
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• 1994

Accoring to the astonlshing progress of medical science, the medical roles of the radiologic technologist are increasing gradually and specializing highly. However, there are the wide disagreements the actual roles of the radiologic technologists at clinics and the relating rules of the medical law. Therefore, it is required that the medical law should be corresponded with the actual state. To solve these problems. this study has proceeded to make the survey of the present medical law and has tried to offer the most suitable theories to the actual state. This study includes the survey of relevant professional literatures. The major contents of this study are as follows. First, medical technician is written "技士" (in Chinese character) at the present medical technician law, and that word is written wrong. So, it should be replaced with "技師". Therefore, radiologic technologist should be written "放射線師". Second, the relations between the doctor and the radiologic tecnologist should be written the "request or other words" instead of "direction". Third, in spite of the rules of the present medical law, the medical act of radiologic technologist at clinics should be belonging to the boundary of medical practice. Forth, to present the appropriate medical service to the patients, legal status of radiologic technologist as a member of medical team should be established. Fifth, it is desired that Magnetic Resonance Imaging Technology as a business of radiologic technologist should be provided for in the medical law.

• Journal of the Korean Society for information Management
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• v.32 no.2
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• pp.25-61
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• 2015

This study was designed to propose library privacy guidelines to be applicable in any library without distinguishing library types. Individual libraries can refine, modify, and use them to fit their situation, using the guidelines as a base. The library privacy protection guidelines developed in this study are composed of purposes, definitions, scope of privacy, law and policy, general information, the library's job performance on the handling of personal information, and library subcontractors. The development objectives and utilization direction of the library privacy guidelines developed in this study are meant to provide a guide for change according to the amended provision of library "Privacy Act" implementation, optimization of library Privacy Directive, a reflection of the relevant laws and regulations, and the standardization-oriented library privacy guidelines.

• Journal of Animal Environmental Science
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• v.1 no.1
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• pp.83-102
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• 1995

Composting is an ecologically sound method of recycling organic waste. Its advantages include the maintenance of soil fertility and improvement of soil physicochemical property. It is an essential part of the waste minimization. That is, composting should be included to increase the recycling rate up to more than 20%. To encourage composting of waste, it is necessary to develop some effective composters of small scale facilities and densely populated areas. For medium and large-size facilities, the optimum process should be selected. Technical counselling and support is desirable for small scale composters for urban residential and rural area. On the other hand, adequate amendment of relevant legislation should be followed to encourage composting. An example of unreasonable legislation is the current fertilizer management act. According to the regulation, the maximum allowable limit of lead in the compost is less than 150ppm, which is too strict. This limit should be increased to at least 300ppm, which is the observed level in most states in USA. At the same time, sound infrastructure should be established and decent publicity work should be achieved to accelerate composting activity. In this paper the desirable standard for some heavy metal concentration in the compost were suggested.

• The Journal of the Korea institute of electronic communication sciences
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• v.8 no.11
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• pp.1755-1762
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• 2013

This study military Act (enacted in 1972) due to the complaint were filed. The first study to address complaints such as integrated systems provide improvement is needed. Second contribution to the community or with the composition of the atmosphere that should provide an instrument to win. Finally, the laws and institutions, regulations, and doctrine in many aspects including the lack of forward thinking, or shall be deemed to be lacking complementary aspects. Studies in the Department of Defense as a reference to the relevant departments so that work is to provide.