• 제목/요약/키워드: relaxation times

검색결과 388건 처리시간 0.022초

EPR을 통한 상자성 자기공명 조영제의 전자스핀 이완시간의 결정 (Determination of Electron Spin Relaxation Time of the Gadolinium-Chealted MRI Contrast Agents by Using an X-band EPR Technique)

  • Sung-wook Hong;Yongmin Chang;Moon-jung Hwang;Il-su Rhee;Duk-Sik Kang
    • Investigative Magnetic Resonance Imaging
    • /
    • 제4권1호
    • /
    • pp.27-33
    • /
    • 2000
  • 목적: 전자상자성 공명(Electron Paramagnetic Resonance EPR)을 사용하여, 현재 상용되고 있는 세가지 상자성 자기공명 조영제, Gd-DTPA, Gd-DTPA-BMA, Gd-DOTA의 전자스핀 이완시간 $T_{le}$를 결정하고자 한다. 대상 및 방법: 본 연구에 사용된 상자성 자기공명 조영제는 Gd-DTPA(Magnevist), Gd-DTPA-BMA(OMNISCAN), Gd-DOTA(Dotarem)이다. 이들 자기공명 조영제들은 2:1 부피 비율의 메탄올과 물의 혼합용액에 희석하여 저온의 glassy상태에서 EPR스펙트럼을 얻었으며, 또한 주어진 영 자기장 갈라지기 (zero-field splitting, ZFS)변수를 $3{\times}3$ 텐서량으로 계산하는 컴퓨터 시뮬레이션 프로그램 'GEN'을 사용하여, 이들 조영제들에 대한 각각 다른 ZFS변수를 가지는 시뮬레이션 스펙트럼을 만들었다. 이 결과들과 McLachlan의 평균이완율 이론을 적용하여 전자스핀 이완시간이 결정되었다. 결과: 상자성 자기공명 조영제 Gd-DTPA, Gd-DTPA-BMA, Gd-DOTA의 전자 횡축 스핀이완시간($T_{2e}$)은 각각 0.113ns, 0.147ns, 1.81ns, g-value는 1,9737, 1.9735, 1.9830, 전자스핀 이완시간($T_{le}$)는 18.70ns, 33.40ns, $1.66{\mu}s$로 결정되었다. 결론: 실험 결과로부터 상자성 자기공명 조영제의 ZFS변수가 클수록 짧은 전자스핀 이완시간 $T_{le}$를 가진다는 일반적인 사실을 재 확인할 수 있었다. 본 연구에 사용된 3가지 자기 공명 조영제들 중에는 화학적으로 환상구조 배위자를 갖는 Gd-DOTA가 가장 긴 전자스핀 이완시간 $T_{le}$를 가지는 것으로 나타나서 일반적으로 환상구조 배위자를 갖는 조영제들이 선상구조 배위자를 갖는 조영제에 비해 전자적인 성질은 우수한 것으로 나타났고 결론적으로 상자성 조명제가 물분자의 자기이완시간에 미치는 영향을 평가하고 고효율 상자성 자기 공명 조영제 개발에는 정확한 ZFS변수 결정이 매우 중요하다는 것을 알 수 있었다.

  • PDF

Effects of relaxation approach with self-exercise on head posture, static postural stability, and headache in persons with tension-type headache

  • Park, Sang-Yong;Hwang, Sujin
    • Physical Therapy Rehabilitation Science
    • /
    • 제5권4호
    • /
    • pp.178-184
    • /
    • 2016
  • Objective: Tension-type headache is caused by hormones, foods, irritants, stress, obesity, fatigue, and neck and head trigger points-prolonged abnormal posture. The purpose of this study was to evaluate the effects of relaxation approach on head posture, static postural stability, and headache in persons with tension-type headache. Design: Randomized controlled trial. Methods: Thirty-five persons with tension-type headache participated in this study. This study was a pretest-posttest with a control group design for a duration of 4 weeks (60 min/3 times/1 wk). The participants were randomly allocated to the relaxation approach group (n=18) and the control group with conventional rehabilitation including thermotherapy and transcutaneous electrical stimulation for the same period (n=17). Outcome measures involved forward head posture (FHP), foot pressure, neck disability index (NDI), and six-item headache impact test (HIT-6). Results: Relaxation approach and control groups improved significantly in the amount of forward head posture, neck disability index, and six-item headache impact test scores after training (p<0.05). The control group was found to be significantly different in the amount of FHP, backward foot pressure, NDI, and HIT-6 after training compared to before training (p<0.05). The relaxation approach group significantly improved in forward head posture, neck disability index, and six-item headache impact test compared with control group after training (p<0.05). Neck disability index and six-item headache impact test significantly improved after training compared with before training in the control group (p<0.05). However, the foot pressure was not significantly different between relaxation approach and control groups. Conclusions: This study suggests that treatment with relaxation approach combined with self-exercise would be effective in reducing the amount of forward head posture, neck disability and headache impacts.

음양곽(淫羊藿)의 토끼 음경해면체 평활근 이완효과 (Relaxation Effects of Epimedium Koreanum Nakai in Isolated Rabbit Corpus Cavernosum Smooth Muscle)

  • 김태연;김호현;박선영;박종필;김정범
    • 동의생리병리학회지
    • /
    • 제28권2호
    • /
    • pp.169-177
    • /
    • 2014
  • This study aimed to investigate the relaxation effects and its underlying mechanisms of Epimedium koreanum Nakai(EK) in phenylephrine(PE) treated isolated rabbit corpus cavernosum smooth muscle. The dose-dependent relaxation responses of phenylephrine(PE, $1{\times}10^{-6}M$)-precontracted strips to EK at $0.01-3.0mg/m{\ell}$ were measured and also observed after endothelial denudation using organ bath. To analyze the underlying mechanisms of EK-induced relaxation, $N{\omega}$-nitro-L-arginine(L-NNA), methylene blue(MB), tetraethylammonium chloride(TEA), indomethacin(IM) were pretreated before EK extract infused into precontracted strips induced by PE. To investigate cytotoxic activity and nitric oxide(NO) concentration of EK extract on EA.hy926 cells, mitochondrial dehydrogenase activity(MTT) assay and nitric oxide detection kit were used. The cavernous strips were significantly relaxed by EK extract at $0.3mg/m{\ell}$, $1.0mg/m{\ell}$, $3.0mg/m{\ell}$ and the relaxation responses of PE-precontracted strips denuded endothelium also inhibited in comparison with intact endothelium. The pretreatment of L-NNA, MB, TEA reduced EK extract-induced endothelium-dependent relaxation, but the pretreatment of IM didn't affect EK extract-induced endothelium-dependent relaxation. When EK extract was applicated on EA.hy926 cells, the NO concentration was increased. Our findings have shown that EK extract exerts a relaxing effect on corpus cavernosum in part by suppressing influx of extracellular $Ca^{2+}$ through activating the NO-cGMP system.

Observation of Methyl Radical Recombination Following Photodissociation of CH3I at 266 nm by Time-Resolved Photothermal Spectroscopy

  • Suh, Myung-Koo;Sung, Woo-Kyung;Li, Guo-Sheng;Heo, Seong-Ung;Hwang, Hyun-Jin
    • Bulletin of the Korean Chemical Society
    • /
    • 제24권3호
    • /
    • pp.318-324
    • /
    • 2003
  • A time-resolved probe beam deflection (PBD) technique was employed to study the energy relaxation dynamics of photofragments produced by photodissociation of $CH_3I$ at 266 nm. Under 500 torr argon environment, experimental PBD transients revealed two energy relaxation processes; a fast relaxation process occurring within an acoustic transit time (less than 0.2 ㎲ in this study) and a slow relaxation process with the relaxation time in several tens of ㎲. The fast energy relaxation of which signal intensity depended linearly on the excitation laser power was assigned to translational-to-translational energy transfer from the photofragments to the medium. As for the slow process, the signal intensity depended on square of the excitation laser power, and the relaxation time decreased as the photofragment concentration increased. Based on experimental findings and reaction rate constants reported previously, the slow process was assigned to methyl radical recombination reaction. In order to determine the rate constant for methyl radical recombination reaction, a theoretical equation of the PBD transient for a radical recombination reaction was derived and used to fit the experimental results. By comparing the experimental PBD curves with the calculated ones, the rate constant for methyl recombination is determined to be $3.3({\pm}1.0)\;{\times}\;10^6\;s^{-1}torr^{-1}$ at 295 ± 2 K in 500 torr Ar.

수도(水稻)의 역학적(力學的) 및 리올러지 특성(特性)에 관(關)한 연구(硏究) (Mechanical and Rheological Properties of Rice Plant)

  • 허윤근;차균도
    • 농업과학연구
    • /
    • 제14권1호
    • /
    • pp.98-133
    • /
    • 1987
  • The mechanical and rheological properties of agricultural materials are important for engineering design and analysis of their mechanical harvesting, handling, transporting and processing systems. Agricultural materials, which composed of structural members and fluids do not react in a purely elastic manner, and their response when subjected to stress and strain is a combination of elastic and viscous behavior so called viscoelastic behavior. Many researchers have conducted studies on the mechanical and rheological properties of the various agricultural products, but a few researcher has studied those properties of rice plant, and also those data are available only for foreign varieties of rice plant. This study are conducted to experimentally determine the mechanical and the rheological properties such as axial compressive strength, tensile strength, bending and shear strength, stress relaxation and creep behavior of rice stems, and grain detachment strength. The rheological models for the rice stem were developed from the test data. The shearing characteristics were examined at some different levels of portion, cross-sectional area, moisture content of rice stem and shearing angle. The results obtained from this study were summarized as follows 1. The mechanical properties of the stems of the J aponica types were greater than those of the Indica ${\times}$ Japonica hybrid in compression, tension, bendingand shearing. 2. The mean value of the compressive force was 80.5 N in the Japonica types and 55.5 N in the Indica ${\times}$ Japonica hybrid which was about 70 percent to that of the Japonica types, and then the value increased progressively at the lower portion of the stems generally. 3. The average tensile force was about 226.6 N in the Japonica types and 123.6 N in the Indica ${\times}$ Japonica hybrid which was about 55 percent to that of the Japonica types. 4. The bending moment was $0.19N{\cdot}m$ in the Japonica types and $0.13N{\cdot}m$ in the Indica ${\times}$ Japonica hybrid which was 68 percent to that of the Japonica types and the bending strength was 7.7 MPa in the Japonica types and 6.5 MPa in the Indica ${\times}$ Japonica hybrid respectively. 5. The shearing force was 141.1 N in Jinju, the Japonica type and 101.4 N in Taebaeg, the Indica ${\times}$ Japonica hybrid which was 72 percent to that of Jinju, and the shearing strength of Taebaeg was 63 percent to that of Jinju. 6. The shearing force and the shearing energy along the stem portion in Jinju increased progressively together at the lower portions, meanwhile in Taebaeg the shearing force showed the maximum value at the intermediate portion and the shearing energy was the greatest at the portion of 21 cm from the ground level, and also the shearing strength and the shearing energy per unit cross-sectional area of the stem were the greater values at the intermediate portion than at any other portions. 7. The shearing force and the shearing energy increased with increase of the cross-sectional area of the rice stem and with decrease of the shearing angie from $90^{\circ}$ to $50^{\circ}$. 8. The shearing forces showed the minimum values of 110 N at Jinju and of 60 N at Taebaeg, the shearing energy at the moisture content decreased about 15 percent point from initial moisture content showed value of 50 mJ in Jinju and of 30 mJ in Taebaeg, respectively. 9. The stress relaxation behavior could be described by the generalized Maxwell model and also the compression creep behavior by Burger's model, respectively in the rice stem. 10. With increase of loading rate, the stress relaxation intensity increased, meanwhile the relaxation time and residual stress decreased. 11. In the compression creep test, the logarithmic creep occured at the stress less than 2.0 MPa and the steady-state creep at the stress larger than 2.0 MPa. 12. The stress level had not a significant effect on the relaxation time, while the relaxation intensity and residual stress increased with increase of the stress level. 13. In the compression creep test of the rice stem, the instantaneous elastic modulus of Burger's model showed the range of 60 to 80 MPa and the viscosities of the free dashpot were very large numerical value which was well explained that the rice stem was viscoelastic material. 14. The tensile detachment forces were about 1.7 to 2.3 N in the Japonica types while about 1.0 to 1.3 N in Indica ${\times}$ Japonica hybrid corresponding to 58 percent of Japonica types, and the bending detachment forces were about 0.6 to 1.1 N corresponding to 30 to 50 percent of the tensile detachment forces, and the bending detachment of the Indica ${\times}$ Japonica hybrid was 0.1 to 0.3 N which was 7 to 21 percent of Japonica types. 15. The detachment force of the lower portion was little bigger than that of the upper portion in a penicle and was not significantly affected by the harvesting period from September 28 to October 20. 16. The tensile and bending detachment forces decreased with decrease of the moisture content from 23 to 13 percent (w.b.) by the natural drying, and the decreasing rate of detachment forces along the moisture content was the greater in the bending detachment force than the tensile detachment force.

  • PDF

진공증착법으로 제조된 $\beta$-PVDF 박막의 유전 특성에 미치는 이온의 영향 (The Effect of Ion Contribution to the Dielectric Properties of $\beta$-PVDF Thin Film Fabricated by Vapor Deposition Method)

  • 박수홍;김종택;이덕출
    • 한국전기전자재료학회논문지
    • /
    • 제11권11호
    • /
    • pp.1007-1013
    • /
    • 1998
  • In this paper, the dielectric properties of fabricated Polyvinylidene fluoride(PVDF, $PVF_2$) thin film with substrate temperature from 30 to at vapor deposition. The dielectric properties of PVDF thin film had been studied in the frequency range from 10Hz to 4MHz at measuring temperature between 20 and $100^{/circ}C$. The anomalous increasing in dielectric constant and dielectric loss at low frequencies and high temperature was described for PVDF thin film containing ion impurities. In particularly, ion mobility of fabricated PVDF thin film at substrate temperature at $30^{/circ}C$ decrease from $2\times10^{-5}\;to\;3.07$\times10^{-7}cm^2/V.s$ On the other hand, ion density increase abruptly from 1.49\times$$10^{13}$ to $1.5\times$10^{16}$cm^{-3}$ In spite of decreasing of ion mobility, dielectric constants and dielectric loss for PVDF thin film increase rapidly with decreasing frequency and high temperature. It was concluded that the dielectric constants and dielectric loss was related to ion density than to ion mobility at low frequency and high temperatures.

  • PDF

Dynamical behavior of generalized thermoelastic diffusion with two relaxation times in frequency domain

  • Sharma, Nidhi;Kumar, Rajneesh;Ram, Paras
    • Structural Engineering and Mechanics
    • /
    • 제28권1호
    • /
    • pp.19-38
    • /
    • 2008
  • A general solution to the field equations of homogeneous isotropic generalized thermoelastic diffusion with two relaxation times (Green and Lindsay theory) has been obtained using the Fourier transform. Assuming the disturbances to be harmonically time.dependent, the transformed solution is obtained in the frequency domain. The application of a time harmonic concentrated and distributed loads have been considered to show the utility of the solution obtained. The transformed components of displacement, stress, temperature distribution and chemical potential distribution are inverted numerically, using a numerical inversion technique. Effect of diffusion on the resulting expressions have been depicted graphically for Green and Lindsay (G-L) and coupled (C-T) theories of thermoelasticity.

A Lagrangian Relaxation Method for Parallel Machine Scheduling with Resource Constraints

  • 김대철
    • 산업공학
    • /
    • 제11권3호
    • /
    • pp.65-75
    • /
    • 1998
  • This research considers the problem of scheduling jobs on parallel machines with non-common due dates and additional resource constraints. The objective is to minimize the total absolute deviation of job completion times about the due dates. Job processing times are assumed to be the same. This problem is motivated by restrictions that occur in the handling and processing of jobs in certain phases of semiconductor manufacturing and other production systems. We examine two problems. For the first of these, the number of different types of additional: resources and resource requirements per job are arbitrary. The problem is formulated as a zero-one integer linear programming and the Lagrangian relaxation approach is used. For the second case, there exists one single type of additional resource and the resource requirements per job are zero or one. We show how to formulate the problem as an assignment problem.

  • PDF

ZPCCY계 바리스터 세라믹스의 소결시간에 따른 전기적, 유전적 특성 (Electrical and Dielectric Properties of ZPCCY-Based Varistor Ceramics with Sintering Time)

  • 남춘우;김향숙
    • 한국전기전자재료학회논문지
    • /
    • 제15권11호
    • /
    • pp.946-952
    • /
    • 2002
  • The electrical and dielectric characteristics of ZPCCY-based varistor ceramics were investigated in the sintering time range of 1∼3 h. Increasing sintering time deteriorated the nonlinearity, in which nonlinear exponent is decreased from 51.2 to 23.8 and leakage current is increased from 1.3 to 5.6 $\mu$A. As sintering time increases, the donor concentration was decreased in the range of (1.25∼l.73)$\times$10$\^$18/cm$\^$-3/ and the density of interface states is (3.64∼94.19)$\times$10$\^$12/cm$\^$-2/ with increasing sintering time. The increase in sintering time caused tan $\delta$ to increase in the range of 0.043 to 0.062 and relaxation time to increase in the range of 1.55 to 2.23 ㎲.

유한한 평판에서 포물선형 및 쌍곡선형 열전도 방정식과 파동 방정식의 비교 해석 (Comparative Analysis of the Parabolic and Hyperbolic Heat Conduction and the Damped Wave in a Finite Medium)

  • 박상규;이용호
    • 동력기계공학회지
    • /
    • 제3권3호
    • /
    • pp.14-21
    • /
    • 1999
  • The wave nature of heat conduction has been developed in situations involving extreme thermal gradients, very short times, or temperatures near absolute zero. Under the excitation of a periodic surface heating in a finite medium, the hyperbolic and parabolic heat conduction equations and the damped wave equations in heat flux are presented for comparative analysis by using the Green's function with the integral transform technique. The Kummer transformation is also utilized to accelerate the rate of convergence of these solutions. On the other hand, the temperature distributions are obtained through integration of the energy conservation law with respect to time. For hyperbolic heat conduction, the heat flux distribution does not exist throughout all the region in a finite medium within the range of very short times(${\xi}<{\eta}_l$). It is shown that due to the thermal relaxation time, the hyperbolic heat conduction equation has thermal wave characteristics as the damped wave equation has wave nature.

  • PDF