• Title/Summary/Keyword: relative risk assessment

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Development of A New Methodology for Evaluating Nuclear Safety Culture (원자력 안전문화의 정량화 방법론 개발)

  • Jae, Moosung;Han, Kiyoon
    • Journal of the Korean Society of Safety
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    • v.30 no.4
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    • pp.174-180
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    • 2015
  • This study developed a Safety Culture Impact Assessment Model (SCIAM) which consists of a safety culture assessment methodology and a safety culture impact quantification methodology. The SCIAM uses safety culture impact index (SCII) to monitor the status of safety culture of the NPPs periodically and it uses relative core damage frequency (RCDF) to present the impact of safety culture on the safety of the NPPs. As a result of applying SCIAM to the reference plant (Kori 3), the standard for the healthy safety culture of the reference plant is suggested. SCIAM might contribute to improve the safety of the NPPs (Nuclear Power Plants) by monitoring the status of safety culture periodically and presenting the standard of healthy safety culture.

Health Risk of Airborne Complex Mixtures Based on their Mutagenicity (대기중 복합물질의 돌연변이원성과 인체 위해도)

  • Park, Seong-Eun;Chung, Yong
    • Journal of Korean Society for Atmospheric Environment
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    • v.12 no.3
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    • pp.269-278
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    • 1996
  • Airborne suspended particulates were collected by an Andersen high volume air sampler in a traffic area of Seoul from September 1990 to August 1991. Origanic matter extracted from particulates, their fractions, namely acidic, basic, neutral and carcinogenic subfractions (PAHs, nitroarenes) in neutral fractions were assayed for mutagenicity on TA98, TA100 and TA98NR deficient Salmonella strains, use of the pre-incubation method. The relative contribution to total mutanenicity of organic matters was highest in neutral fraction and was lowest in basic fraction. Among subfractions, that of neutral fraction was higher nitroarenes subfraction compared to PAHs subfraction. While the carcinogenic effect of benzo[a]pyrene was calculated as 0.96 persons/million persons based on unit risk estimates by extrapolation method, life time excess cancer risk estimate of EOM, neutral, PAH fraction based on their mutagenicity was calculated as 52, 42, 3.8 persons/million persons, respectively. These findings indicate that the mutagenic hazard of the partciculate, air organic complex mixture, may be dependent upon the mutagen composition in the particulate and interactions each of them. Therfore, health risk from air organic complex mixtures based on mutagenicity might be useful indicator for evaluation of actual risk.

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Relative Advantage and Risk of Information Systems Outsourcing : An Empirical Assessment (정보시스템 아웃소싱의 상대적 이점과 위험 : 경험적 연구)

  • 이민화
    • Proceedings of the Korea Association of Information Systems Conference
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    • 1997.10a
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    • pp.527-546
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    • 1997
  • 정보시스템 기능의 아웃소싱이 정보시스템 효율과 효과성을 개선하기 위한 하나의 전략으로 고려됨에 따라서 소싱설정의 결정요인을 식별하는 것은 중요하다. 본 연구는 금융 산업에 있어서 자료처리 서비스에 대한 소싱결정에 영향을 주는 요인들을 조사하였다. 아웃 소싱이 관리적 혁신으로 간주될 수 있기 때문에, 기존의 연구를 기초로 하여 혁신특성으로 서 상대적 이점과 위험을 소실설정의 중요한 결정요인으로 제시한다. 미국의 1,000개의 은 행을 대상으로 조사한 결과는 상대적 이점과 위험이 정보시스템 아웃소싱 및 아웃소싱 선호 도와 유의적인 관계가 있음을 보여준다.

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Risk Assessment for Heavy Metals in Korean Foods and Livestock Foodstuffs (한국인의 대표식품 및 축산식품에 대한 중금속 위해도 평가)

  • Kwon, Young-Min;Lee, Kyoung-Hee;Lee, Haeng-Shin;Park, Seon-Oh;Park, Jung-Min;Kim, Jin-Man;Kang, Kyung-Mo;No, Ki-Mi;Kim, Dong-Sul;Lee, Jong-Ok;Hong, Moo-Ki;Choi, Dal-Woong
    • Food Science of Animal Resources
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    • v.28 no.3
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    • pp.373-389
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    • 2008
  • This study was conducted to evaluate exposure level and risk of heavy metals in livestock foodstuffs and Korean foods. Based on the "Food Intake Data," a part of the 2005 National Health & Nutrition Survey and the "2005 Seasonal Nutrition Survey", 113 Korean foods items were selected. 3 samples from different manufacturers of each 113 items of Korean foods were purchased on summer and fall, so total 678 samples were used. The food groups were classified into 15 categories. For the livestock foodstuffs category, meats and poultry (chicken, pork, pork belly, beef, beef feet soup), milks and dairy products (milk, ice cream, liquid yoghourt, sherbet), eggs (egg) were selected. It was found that the daily amount of heavy metals intake (mg/person/day) from livestock foodstuffs is 0.00020 arsenic, 0.00000 cadmium, 0.00020 lead, and 0.00006 mercury, and the daily amount of heavy metals intake (mg/person/day) from Korean foods is 0.0265 arsenic, 0.0083 cadmium, 0.0067 lead, and 0.0028 mercury. Daily amount of heavy metals intake from livestock foodstuffs was low among the food groups. For risk assessment, PDI (Probable Daily Intake) was calculated and compared with PTWI (Provisional Tolerable Weekly Intake) of JECFA (Joint FAO/WHO Expert Committee on Food Additive). Relative hazard of these livestock foodstuffs was 0.006% in arsenic, 0.000% in cadmium, 0.085% in lead, and 0.149% in mercury. Relative hazard of Korean foods was 0.941% in arsenic, 14.676% in cadmium, 3.319% in lead, and 6.860% in mercury. Thus, livestock foodstuffs and Korean foods were as safe as satisfied with the recommended standards of JECFA.

Assessment of Ki-67 for Predicting Effective Prognosis in Breast Cancer Subtypes

  • Park, Sangjung;Park, Sunyoung;Kim, Jungho;Ahn, Sungwoo;Park, Kwang Hwa;Lee, Hyeyoung
    • Biomedical Science Letters
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    • v.24 no.1
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    • pp.9-14
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    • 2018
  • Ki-67 has been widely performed and become an important biomarker in worldwide clinics, but the standard cut off value of Ki-67 index in breast cancer is still controversy. The objective study was to understand the Ki-67 in breast cancer subtypes and to investigate relative risk of breast cancer subtypes according to Ki-67 cut off value in Korean breast cancer. Immunohistochemical staining (IHC) for estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2), and Ki-67 index was examined from 123 breast cancer patients. Ki-67 index was significantly overexpressed in PR, ER, and HER2 hormone negative groups. Ki-67 index in Triple negative and HER2 subtypes was shown significantly higher than that in Luminal A and Luminal B subtype. Then, we compared the relative risk of each subtype according to 14% and 20% Ki-67 cut off value, which were applied in most clinics. Especially, 20% Ki-67 cut off value in HER2 and Triple negative subtypes was shown 8.41 fold and 2.83 fold higher relative risk than this in Luminal A subtype. Moreover, Ki-67 index in HER2 2+ or 3+ status showed significantly overexpressed than this in HER2 1+ status. At the 20% Ki-67 cut off value, HER2 1+ or 2+ status and 3+ status showed significant difference. Therefore, the 20% Ki-67 cut off value will be useful as a precise prognostic management and helpful for interpreting diverse outcomes of other subtypes in breast cancer patients.

Development of analytical method for cyantraniliprole residues in welsh onion (Allium species) (대파(Allium속)에서 살충제 Cyantraniliprole 잔류분석을 위한 시험법 개발)

  • Do, Jung-Ah;Lee, Mi-Young;Chang, Moon-Ik;Hong, Jin-Hwan;Oh, Jae-Ho
    • Analytical Science and Technology
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    • v.28 no.3
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    • pp.175-181
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    • 2015
  • Cyantraniliprole, which is an ananthranilic diamide insecticide that was developed by the DuPont Corporation, was registered in the Republic of Korea in 2012. It offers exceptional insecticidal activity on a broad range of Lepidopera, Coleoptera, Diptera, and Isoptera. The maximum residue limits are set to pepper, peach, apple, sweet pepper, welsh onion, and so on (0.2~2.0 mg/kg). Therefore, an analytical method for determining cyantraniliprole residue in agricultural products was developed to ensure food safety. In previous studies, welsh onions were among vegetables included in the allium species, which is a representative plant with sulfur organic compounds. In this study, the analytical method was developed and evaluated for the elimination of sulfur compounds from the test solution of allium species during pesticide residue analysis. In order to inactivate the enzyme allinase and produce sulfur compounds, sample extraction was made in the base state pH 10 by reducing the activity of the enzyme. The recoveries of the developed method ranged from 81.9% to 83.2%, and the relative standard deviations were less than 10%. Therefore, based on the results, the method developed in this study is accurate and appropriate for use in cyantraniliprole determination. It will be used as the official method for managing the safety of cyantraniliprole residues in agricultural products.

The Assessment of Survey on the Indoor Air Quality at Schools in Korea (국내 일부학교 건축물의 실내공기질 평가)

  • Sohn Jong-Ryeul;Roh Young-Man;Son Bu-Soon
    • Journal of Environmental Health Sciences
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    • v.32 no.2 s.89
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    • pp.140-148
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    • 2006
  • Recently, indoor air quality (IAQ) in workplace, residential environments and schools has been concerned of people, scientists and related the public, and has recognized the health effects related to indoor air pollution. Therefore, this study was performed to investigate the characteristics of IAQ in 55 kindergartens, elementary school, middle schools, and high schools from June, 2004 to May, 2005 in Korea. We measured indoor air pollutants($PM_{10},\;CO_2$, HCHO, total bacteria colony(TBC), CO, radon, TVOCs, asbestos, and $O_3$), and physical factors(noise, temperature, relative humidity, and illumination) with necessary of management for IAQ in school. We classified into 5 kinds of the school by period since building completion, <1 year, 1-3 years, 3-5 years, and 5-10 years. The concentration of pollutants and the level of physical factors compared with standards and guidelines of IAQ on the Ministry of Environment, the Ministry of Health and Welfare, and the Ministry of Education and Human Resources Development. The major results obtained from this study were as follows. Temperature, relative humidity and illumination among the physical factors did not exceed the standards, but noise exceeded it. Asbestos and $O_3$ did not detect in surveyed classrooms. CO, TBC, TVOCs, and HCHO in kindergartens, TBC in elementary schools, TBC, TVOCs dnd HCHO in middle schools, and HCHO in high schools detected the standards. This study is conducted as a part of efforts to provide a foundational data for further relative researches on management of IAQ of school. Therefore, we suggest that country plan for management of IAQ in school should be established through long-term and continuous investigation for assessment on IAQ in school and health risk assessment for students.

Identification and Structuring of the Workplace Risk Factors Regarding Power Press Machines

  • Kuk, Kang-Hur;Park, Dong-Hyun
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.23 no.56
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    • pp.65-85
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    • 2000
  • Industrial accidents have been consistently increased in terms of medical costs, lost work days, and incidence rates every year in Korea. Since the infrastructure of the industry changed shifts rapidly from 1980s in the developing countries such as South Korea, the nature and magnitude of the industrial accidents have also undergone a major shift. The situation is especially severe in small-to-medium sized industry(SMI). This article reports the development of a systematic evaluation system of risk factors specifically for the SMIs. The new approach introduced by this article is geared to the systematic identification and evaluation of the injuries from power press machines using the Analytic Hierarchy Process with the key evaluation data generated and evaluated by the employees on site. A total of 21 companies was studied and surveyed using the hierarchical structures of the cause-effect relationship of the mechanical injuries and their countermeasures. For the relative weighting of each risk factor, separate questionnaire survey was conducted for the selected workers from each company who had worked for more than 10 years in press work. Most participants (48 out of 62) replied that human attributes were the most significant factors for mechanical injuries fellowed by administration, machine, and work environment factors. The result also showed that the self-motivated risk assessment and safety enhancement activities would be an effective and efficient way of managing the risk factors in the SMIs.

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Seismic vulnerability assessment criteria for RC ordinary highway bridges in Turkey

  • Avsar, O.;Yakut, A.
    • Structural Engineering and Mechanics
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    • v.43 no.1
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    • pp.127-145
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    • 2012
  • One of the most important and challenging steps in seismic vulnerability and performance assessment of highway bridges is the determination of the bridge component damage parameters and their corresponding limit states. These parameters are very essential for defining bridge damage state as well as determining the performance of highway bridges under a seismic event. Therefore, realistic damage limit states are required in the development of reliable fragility curves, which are employed in the seismic risk assessment packages for mitigation purposes. In this article, qualitative damage assessment criteria for ordinary highway bridges are taken into account considering the critical bridge components in terms of proper engineering demand parameters (EDPs). Seismic damage of bridges is strongly related to the deformation of bridge components as well as member internal forces imposed due to seismic actions. A simple approach is proposed for determining the acceptance criteria and damage limit states for use in seismic performance and vulnerability assessment of ordinary highway bridges in Turkey constructed after the 1990s. Physical damage of bridge components is represented by three damage limit states: serviceability, damage control, and collapse prevention. Inelastic deformation and shear force demand of the bent components (column and cap beam), and superstructure displacement are the most common causes for the seismic damage of the highway bridges. Each damage limit state is quantified with respect to the EDPs: i.e. curvature and shear force demand of RC bent components and superstructure relative displacement.