• Title/Summary/Keyword: relative risk assessment

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Diabetes Mellitus Reduces Prostate Cancer Risk - No Function of Age at Diagnosis or Duration of Disease

  • Xu, Hua;Mao, Shan-Hua;Ding, Guan-Xiong;Ding, Qiang;Jiang, Hao-Wen
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.1
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    • pp.441-447
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    • 2013
  • Background: Prior studies examining the relation between diabetes mellitus (DM) and prostate cancer risk have reported controversial findings. We examined this association by conducting a detailed meta-analysis of the peer-reviewed literature. Methods: A comprehensive search for articles of MEDLINE and EMBASE databases and bibliographies of retrieved articles published up to November, 2012 was performed. Methodological quality assessment of the trials was based on the Newcastle-Ottawa Scaleq and the meta-analysis was performed using STATA 12.0. Dose-response regression was conducted with SPSS 19.0. Results: We included 29 studies in the meta-analysis (13 case-control studies, 16 cohort studies), and found an inverse association between DM and prostate cancer (relative risk (RR) 0.84, 95% confidence interval (CI), 0.78-0.91). An inverse association was also observed in non-Asian populations (RR 0.81, 95% CI 0.76-0.87) and population-based studies (RR 0.80, 95% CI 0.77-0.91). No statistical significance was found of the association between prostate cancer risk and the duration of DM (p=0.338), and risk seemed not related with the age of DM diagnosis. Conclusions: This study suggested an inverse relationship between DM and prostate cancer, but without links to duration of disease or age of diagnosis.

Persistence and Degradation Pattern of Acequinocyl and Its Metabolite, Hydroxyl-Acequinocyl and Fenpyroximate in Butterburs (Petasites japonicus Max.)

  • Leesun Kim;Geun-Hyoung Choi;Hyun Ho Noh;Hee-Dong Lee;Hak-won Lee;Kee Sung Kyung;Jin-Ho Ro
    • Korean Journal of Environmental Agriculture
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    • v.42 no.2
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    • pp.93-103
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    • 2023
  • Persistence and degradation patterns of acequinocyl and its metabolite, hydroxyl-acequinocyl (acequinocyl-OH) and fenpyroximate in butterburs (Petasites japonicus Max.) were investigated after pesticide application. Butterburs, one of the minor crops in South Korea, was planted in two plots (plot A for double and plot B for single application) in a greenhouse. Butterburs samples were also planted in a separate plot without pesticide treatment, as the control. A commercial pesticide containing acequinocyl and fenpyroximate was applied to the foliage of butterburs at hourly intervals after dilution. Recoveries of acequinocyl and acequinocyl-OH were 78.6-84.7% and 83.7-95.5%, respectively; the relative standard deviation of the two compounds were less than 5%. The method limit of quantification was 0.01 mg/kg. The total (Ʃ) acequinocyl residues in butterburs reduced by 96.0% at 14 days and 75.9% at 7 days, in plot A and B, respectively, after final pesticide applications. The biological half-life (DT50) of Ʃ acequinocyl and fenpyroximate, calculated using the dissipation rate, was 3.0 days and 4.0 days, respectively. These data were used to set up maximum residue and safe standard levels when the pesticides are applied to control pests during butterbur cultivation. Risk assessment results showed that the maximum % acceptable daily intake was 7.74% for Ʃ acequinocyl and 0.16% for Ʃ fenpyroximate. The theoretical maximum daily intake of Ʃ acequinocyl and fenpyroximate was 26.3% and 35.8%, respectively. In conclusion, the concentrations of Ʃ acequinocyl and fenpyroximate in butterburs pose no significant health risks to Koreans.

The Study on the Atmospheric Corrosion Tests of Materials in Northeast Asia (동북 아시아 지역에서의 대기중 재료부식 시험에 관한 연구)

  • 김선태;임봉빈
    • Journal of Environmental Science International
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    • v.7 no.3
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    • pp.361-368
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    • 1998
  • The structure such as building and cultural properties was composed of various materials like wood, metal and stone that have been utilized and exposed to air, wind and rain far a long time. However, because of their special characteristics as structure, collecting of samples that may involve their destruction cannot be permitted, ever for material analysis. Therefore, h order to study the Influence of atmospheric pollution on structure, atmospheric corrosion tests were achieved by making use of materials(bronze. ancient copper, copper, steel and marble) in field exposure tests. Atmospheric exposure sites are selected from places which are characterized by urban, rural, Industrial and marine enoronments In Northeast Asia. According to the results of atmospheric corrosion tests: The corrosion rates of Industrial states In china were more serious than other sampling sites. In the correlation of meteorological factors. wet hours was defiled as Intogeacted hours under that atmospheric temperature is above $0^{\circ}C$ and relative humidity in above 80% that has a great influence on corrosion tests of materials in case of a short time. The relative humidity was above about 75% that resulted in great increase of corrosion rates. In the esimation of corrosion rates between materials, corrosion rates of steel was about thirty times and decuple larger than that of other materials excluding marble in unshelterd exposure and In sheltered exposure.

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An Analysis of the Relative Importance of Security Level Check Items for Autonomous Vehicle Security Threat Response (자율주행차 보안 위협 대응을 위한 보안 수준 점검 항목의 상대적 중요도 분석)

  • Im, Dong Sung
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.21 no.4
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    • pp.145-156
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    • 2022
  • To strengthen the security of autonomous vehicles, this study derived checklists through the analysis of the status of autonomous vehicle security. The analyzed statuses include autonomous vehicle characteristics, security threats, and domestic and foreign security standards. The derived checklists are then applied to the AHP(Analytic Hierarchy Process) model to find their relative importance. Relative importance was ranked as one of cyber security management system establishment and implementation, encryption, risk assessment, etc. The significance of this study is to reduce cyber security incidents that cause human casualties as well improve the level of security management of autonomous vehicles in related companies by deriving the autonomous vehicle security level checklists and demonstrating the model. If the inspection is performed considering the relative importance of the checklists, the security level can be identified early.

An Application of the Rough Set Approach to credit Rating

  • Kim, Jae-Kyeong;Cho, Sung-Sik
    • Proceedings of the Korea Inteligent Information System Society Conference
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    • 1999.10a
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    • pp.347-354
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    • 1999
  • The credit rating represents an assessment of the relative level of risk associated with the timely payments required by the debt obligation. In this paper, we present a new approach to credit rating of customers based on the rough set theory. The concept of a rough set appeared to be an effective tool for the analysis of customer information systems representing knowledge gained by experience. The customer information system describes a set of customers by a set of multi-valued attributes, called condition attributes. The customers are classified into groups of risk subject to an expert's opinion, called decision attribute. A natural problem of knowledge analysis consists then in discovering relationships, in terms of decision rules, between description of customers by condition attributes and particular decisions. The rough set approach enables one to discover minimal subsets of condition attributes ensuring an acceptable quality of classification of the customers analyzed and to derive decision rules from the customer information system which can be used to support decisions about rating new customers. Using the rough set approach one analyses only facts hidden in data, it does not need any additional information about data and does not correct inconsistencies manifested in data; instead, rules produced are categorized into certain and possible. A real problem of the evaluation of the evaluation of credit rating by a department store is studied using the rough set approach.

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LCOE Assessment of Major Power Generation Technologies Reflecting Social Costs (사회적 비용을 고려한 국내 주요 발전기술의 균등화발전비용 산정)

  • Cho, Young-Tak;Seok, Kwanghoon;Park, Jong-Bae
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.67 no.2
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    • pp.179-185
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    • 2018
  • A considerable cost gap between three major power generation technologies, namely nuclear, coal, and combined cycle gas turbine (CCGT), has been a well-established fact in the Korean electricity market. Alternatively, this paper analyzes the levelized costs of electricity (LCOE) of the three technologies reflecting overall social costs of electricity generation including accident risk, $CO_2$ emission, and air pollution damage. The paper unveils to what extent current discriminative subsidies on fuels regarding the social costs, mostly through tax exemptions, affect economic competitiveness of the technologies. In particular, it finds relative positions of coal and CCGT could be altered depending on appreciation level of the social costs. It has limits in analyzing fixed costs of the technologies, however, due to limited data availability of nuclear power, and suggests further studies on the issue.

Evaluation and Analysis of VR Content Dementia Prevention Training based on Musculoskeletal Motion Tracking (근골격계 동작 추적 기반 VR 콘텐츠 치매 예방 훈련 평가 및 분석)

  • Lee, Min-Tae;Youn, Jae-Hong;Kim, Eun-Seok
    • Journal of Korea Multimedia Society
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    • v.23 no.1
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    • pp.15-23
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    • 2020
  • Recently, the increase in the elderly population due to an aging society has led to a relative increase in senile diseases such as vascular dementia or Alzheimer's disease, and the social burden for rehabilitation has increased. In addition, studies have been conducted for the risk assessment and prevention of musculoskeletal disorders. The purpose of this study is to suggest a system that can be used to help with dementia prevention training by tracking the movement of motion and virtual reality contents for the risk factors of musculoskeletal disorders of the elderly. We propose a training method for preventing dementia through musculoskeletal motion analysis algorithm and virtual reality content. Through motion recognition algorithm based on motion region design, we will track and analyze the moving radius of the target joint. The purpose of this study is to calculate and evaluate scores based on the time to accomplish the goals on virtual reality contents for the prevention of musculoskeletal disorders and the support of dementia prevention training, and the degree of difficulty, and to analyze the correlation between the results of performing K-MMSE and VR contents.

Number of Steps and Time to Accomplish Turning During Timed Up and Go Test in Community-Dwelling Elderlies With and Without Idiopathic Parkinson Disease

  • Choi, Bong-sam;Lim, Woo-taek
    • Physical Therapy Korea
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    • v.23 no.4
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    • pp.47-54
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    • 2016
  • Background: Losing balance during locomotive actions becomes an increasing threat to both the community-dwelling elderly and elderly with Parkinson disease (PD). Those with PD may be at a high risk of fall due to particular characteristics during the turn. Turning around during locomotive actions may be one of problematic factors causing losing balance. Objects: This study is part of a larger study, which in part aims to identify turning strategies, to compare the strategies in the elderly with and without idiopathic PD aged 51 years and older and to distinguish whether the turning strategies can predict the elderly at risk of falls. Methods: A total of 22 community-dwelling elderlies (10 elderlies with idiopathic PD and 12 healthy elderlies) were investigated for the turning strategies during the timed up and go test. Results: There were some significant differences between the two groups during turning (p<.05). The idiopathic PD group had a tendency of challenging on taking more number of steps, more time to accomplish and staggering more for the turn relative to the control group. Conclusion: Taking more number of steps and more time to turn may be useful for distinguishing the characteristics of PD from that of the healthy elderly in turning strategy.

Uncertainty Analysis for Parameters of Probability Distribution in Rainfall Frequency Analysis by Bayesian MCMC and Metropolis Hastings Algorithm (Bayesian MCMC 및 Metropolis Hastings 알고리즘을 이용한 강우빈도분석에서 확률분포의 매개변수에 대한 불확실성 해석)

  • Seo, Young-Min;Park, Ki-Bum
    • Journal of Environmental Science International
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    • v.20 no.3
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    • pp.329-340
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    • 2011
  • The probability concepts mainly used for rainfall or flood frequency analysis in water resources planning are the frequentist viewpoint that defines the probability as the limit of relative frequency, and the unknown parameters in probability model are considered as fixed constant numbers. Thus the probability is objective and the parameters have fixed values so that it is very difficult to specify probabilistically the uncertianty of these parameters. This study constructs the uncertainty evaluation model using Bayesian MCMC and Metropolis -Hastings algorithm for the uncertainty quantification of parameters of probability distribution in rainfall frequency analysis, and then from the application of Bayesian MCMC and Metropolis- Hastings algorithm, the statistical properties and uncertainty intervals of parameters of probability distribution can be quantified in the estimation of probability rainfall so that the basis for the framework configuration can be provided that can specify the uncertainty and risk in flood risk assessment and decision-making process.

$PM_{10}$ Exposure and Non-accidental Mortality in Asian Populations: A Meta-analysis of Time-series and Case-crossover Studies

  • Park, Hye Yin;Bae, Sanghyuk;Hong, Yun-Chul
    • Journal of Preventive Medicine and Public Health
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    • v.46 no.1
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    • pp.10-18
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    • 2013
  • Objectives: We investigated the association between particulate matter less than $10{\mu}m$ in aerodynamic diameter ($PM_{10}$) exposure and non-accidental mortality in Asian populations by meta-analysis, using both time-series and case-crossover analysis. Methods: Among the 819 published studies searched from PubMed and EMBASE using key words related to $PM_{10}$ exposure and non-accidental mortality in Asian countries, 8 time-series and 4 case-crossover studies were selected for meta-analysis after exclusion by selection criteria. We obtained the relative risk (RR) and 95% confidence intervals (CI) of non-accidental mortality per $10{\mu}g/m^3$ increase of daily $PM_{10}$ from each study. We used Q statistics to test the heterogeneity of the results among the different studies and evaluated for publication bias using Begg funnel plot and Egger test. Results: Testing for heterogeneity showed significance (p<0.001); thus, we applied a random-effects model. RR (95% CI) per $10{\mu}g/m^3$ increase of daily $PM_{10}$ for both the time-series and case-crossover studies combined, time-series studies relative risk only, and case-crossover studies only, were 1.0047 (1.0033 to 1.0062), 1.0057 (1.0029 to 1.0086), and 1.0027 (1.0010 to 1.0043), respectively. The non-significant Egger test suggested that this analysis was not likely to have a publication bias. Conclusions: We found a significant positive association between $PM_{10}$ exposure and non-accidental mortality among Asian populations. Continued investigations are encouraged to contribute to the health impact assessment and public health management of air pollution in Asian countries.