• Journal of Nutrition and Health
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• 제29권7호
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• pp.778-787
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• 1996

The purpose of present study was to assess the change of bone mineral density(BMD) and the influences of anthroopometric indices and body composition on BMD in Korean women in Taegu. Subjects were 242 healthy female in the range of 7-67 years old, were divided into 4 age groups in order to assess the influence o factors on BMD according to age. Body composition and BMD measurements of lumbar spine, femur(neck, ward's triangle, trochanter) and total body were performed by dual energy X-ray absorptiometry. The analysis indicated that BMD of most region was positively related to body weight, BMI in all groups 4(50-67years), and closely related to femurs than lumbar spine. This study found correlations between BMD and both total fat body mass and total lean body mass in group 1, 2, 3, and correlations between BMD and only total fat body mass and in group 4. But on regression models the most significant prediction of BMD throughout the skeleton was total lean body mass in group 1(7-16years)and 2(17-34years, and total fat body mass in group 3 and 4. It is concluded that the our data can be used to screen early women of low bone mass. This study confirms that one of the most effective way to prevent osteoporosis and the fractures is to maximize peak bone mass in early life and to minimize bone loss through maintaining adequate weight.

• 대한물리의학회지
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• 제9권3호
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• pp.301-305
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• 2014

PURPOSE: The purpose of this study was to determine the optimal thresholds of serum lipid level related to hypertension according to age in Korean adults. METHODS: In total, 564 adults who visited the health examine center in general hospital were included. The blood pressure and lipid profiles of low density lipoprotein cholesterol(LDL), high density lipoprotein cholesterol (HDL), triglyceride(TG) were measured. Receiver operating characteristic (ROC) curve were used to establish optimal thresholds between blood pressure and lipid profiles. RESULTS: The optimal TG cutoff value were 110.50(mg/dl) in the 18-39 and 81.50(mg/dl) in the 40-59 age group, and optimal cutoff value of LDL were 126.50(mg/dl) in the 40-59 age group and 111.00(mg/dl) in the 60 and over age group. There was a negative correlation between HDL and hypertension, a higher HDL decreased hypertension. The optimal cutoff value of HDL was 49.50(mg/dl) in the 18-39 age group. CONCLUSION: The thresholds of hypertension were lower in LDL and TG with aging. This result indicated that elderly people needs to concern more about their lipid profiles to maintain healthy cardiovascular function.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1929-1933
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• 2012

Oxidative stress has been proposed to be involved in colorectal cancer development. Many dark pigments of plants have potent oxidative stress preventive properties. In this study, unpolished Thai rice was assessed for antioxidant activity using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) methods. Red strain unpolished Thai rice was also administered to rats exposed to azoxymethane (AOM) for induction of aberrant crypt foci (ACF). Serum malondialdehyde (MDA) and ferric reducing antioxidant power (FRAP) were investigated for cellular oxidative stress and serum antioxidants, respectively. Red pigment unpolished Thai rice demonstrated high antioxidant activity and was found to significantly and dose dependently decrease the total density and crypt multiplicity of ACF. Consumption of Thai rice further resulted in high serum antioxidant activity and low MDA cellular oxidative stress. Interestingly, the density of ACF was strongly related to MDA at r = 0.964, while it was inversely related with FRAP antioxidants (r = -0.915, p < 0.001). The results of this study suggest that the consumption of red strain of unpolished Thai rice may exert potentially beneficial effects on colorectal cancer through decrease in the level of oxidative stress.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2008년도 춘계학술대회 논문집
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• pp.158-167
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• 2008

The quality control of compacted fills has been carried out by evaluating relative densities and coefficients of soil reaction. These measures have several limitations regarding repeatability and reliability of field measurements, and difficulties to use in the fills including large grain size as gravels and boulders. Also, the density is not directly related to the design parameter such as resilient modulus. A preliminary investigation for the usage of the stiffness as a control measure has been carried out. In the laboratory, the stiffness (P-wave velocity) was measured during compaction tests. The stiffness at the optimal moisture content was proposed to use a target control parameter likewise maximum dry density. A field method to match the target stiffness was also proposed by considering easiness of the method and availability of equipment. The most phenomenal feature of the method is that the control parameter (stiffness) is closely related to resilient modulus and can be consistently used from the design stage to the field control during construction.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2013년도 추계학술대회 논문집
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• pp.362-367
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• 2013

Vehicle CAE models for NVH predictions are largely developed in two schemes. One is FE models generally used for below 200 Hz problems such as booming noise, and the other is SEA models for high frequencies of more than 1 kHz, representatively related to sound packages. HMC has tried to develop a CAE model for 200-1000 Hz, so-called mid-frequency region, and this paper is one of the corresponding results. The CAE model is developed based on an FE model, and then FE elements at some areas are substituted with SEA elements to reduce DOFs. SEA panels are described by modal density, radiation efficiency, stiffness and damping characteristics that are found from some numerical assessments. Sound packages are modeled similarly as a conventional SEA model. The CAE model developed in this manner, the hybrid model, was compared to experimental results. Predicted pressure and vibrational velo city generally show a good agreement. The developed CAE model and related technology are successfully being used in vehicle development process.

• Journal of Ecology and Environment
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• 제47권2호
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• pp.35-41
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• 2023

Background: Several species of amphibians in agricultural areas are often infected with ranaviruses; however, the biological or ecological factors that cause this infection are not well understood. In this study, we investigated whether local tadpole density, Gosner developmental stage, and weather conditions affected ranavirus infection in Dryophytes japonicus tadpoles in rice paddies over three months. Results: During the study, eight samplings were undertaken between June 6 and August 21, 2022. No die-off of tadpoles occurred, but 20 of 110 tadpoles (18.8%) were found to be infected with ranavirus. The tadpole density at the sampling site and Gosner stage of the sampled tadpoles were not related to the daily ranavirus infection rate. The mean daily highest temperature during the two weeks prior to the sampling date and the mean daily lowest and highest temperatures during the week prior to the sampling date were negatively related to the daily infection rate. Conclusions: Our results suggest that low and extreme temperatures caused by flooding and draining of paddy fields or climate change in summer could be a significant risk factor for ranavirus infection in summer-breeding frogs in agricultural areas.

• Steel and Composite Structures
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• 제51권4호
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• pp.363-375
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• 2024

Within the optimization field, addressing the intricate posed by fluidic pressure loads on functionally graded structures with frequency-related designs is a kind of complex design challenges. This paper thus introduces an innovative density-based topology optimization strategy for frequency-constraint functionally graded structures incorporating Darcy's law and a drainage term. It ensures consistent treatment of design-dependent fluidic pressure loads to frequency-related structures that dynamically adjust their direction and location throughout the design evolution. The porosity of each finite element, coupled with its drainage term, is intricately linked to its density variable through a Heaviside function, ensuring a seamless transition between solid and void phases. A design-specific pressure field is established by employing Darcy's law, and the associated partial differential equation is solved using finite element analysis. Subsequently, this pressure field is utilized to ascertain consistent nodal loads, enabling an efficient evaluation of load sensitivities through the adjoint-variable method. Moreover, this novel approach incorporates load-dependent structures, frequency constraints, functionally graded material models, and polygonal meshes, expanding its applicability and flexibility to a broader range of engineering scenarios. The proposed methodology's effectiveness and robustness are demonstrated through numerical examples, including fluidic pressure-loaded frequency-constraint structures undergoing small deformations, where compliance is minimized for structures optimized within specified resource constraints.

• 한국토양비료학회지
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• 제46권5호
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• pp.333-342
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• 2013

Soil compaction is affected by soil texture, organic matter (OM), strength (ST) and soil moisture, which is difficult to understand the degree and effects of related factors. The purpose of the study is to assess the impact of them on the compaction with bulk density (BD). The analysis was conducted with data collected from national-wide monitoring sites including 105 upland soils, 246 orchard soils, and 408 paddy soils between 2009 and 2012. The distributions of soil physical properties were measured. The correlation and multi linear regression analysis were performed between soil physical properties using SAS. The regression equation of BD(y) includes ST, gravitational water contents (GWC), and OM as variables commonly, having additional factors, clay content and sand content in paddy soil and upland soil for only subsoil (p<0.001). Our results show that the BD could be explained about 40~50% by various physical properties. The regression was mainly determined by ST in orchard and upland soil and by the GWC in paddy soil. To mitigate soil compaction, it is important to maintain the proper level of OM in upland soil and to consider the moisture condition with soil texture in paddy soil when making work plan. Furthermore, it would be recommended the management criteria classified by soil texture for the paddy soils.

• Journal of Korean Neurosurgical Society
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• 제48권2호
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• pp.125-128
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• 2010

Objective : The purpose of this study was to determine the optimal volume of injected cement and its distribution when used to treat vertebral compression fractures, and to identify factors related to subsequent vertebral fractures. Methods : A retrospective analysis of newly developing vertebral fractures after percutaneous vertebroplasty was done. The inclusion criteria were that the fracture was a single first onset fracture with exclusion of pathologic fractures. Forty-three patients were included in the study with a minimum follow up period of six months. Patients were dichotomized for the analysis by volume of cement, initial vertebral height loss, bone marrow density, and endplate-to-endplate cement augmentation. Results : None of the four study variables was found to be significantly associated with the occurrence of a subsequent vertebral compression fracture. In particular, and injected cement volume of more or less that 3.5 cc was not associated with occurrence (p = 0.2523). No relation was observed between initial vertebral height loss and bone marrow density (p = 0.1652, 0.2064). Furthermore, endplate-to-endplate cement augmentation was also not found to be significantly associated with a subsequent fracture (p = 0.2860) by Fisher's exact test. Conclusion : Neither volume of cement, initial vertebral height loss, bone marrow density, or endplate-to-endplate cement augmentation was found to be significantly related to the occurrence of a subsequent vertebral compression fracture. Our findings suggest that as much cement as possible without causing leakage should be used.

• Nutrition Research and Practice
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• 제12권4호
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• pp.298-306
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• 2018

BACKGROUND/OBJECTIVES: Obesity is a global health problem of significant importance which increases mortality. In place of anti-obesity drugs, natural products are being developed as alternative therapeutic materials. In this study, we investigated the effect of Brassica juncea L. leaf extract (BLE) on fat deposition and lipid profiles in high-fat, high-cholesterol diet (HFC)-induced obese rats. MATERIALS/METHODS: Male Sprague-Dawley rats were divided into four groups (n = 8 per group) according to diet: normal diet group (ND), high-fat/high-cholesterol diet group (HFC), HFC with 3% BLE diet group (HFC-A1), and HFC with 5% BLE diet group (HFC-A2). Each group was fed for 6 weeks. Rat body and adipose tissue weights, serum biochemical parameters, and tissue lipid contents were determined. The expression levels of mRNA and proteins involved in lipid and cholesterol metabolism were determined by reverse transcription polymerase chain reaction and western blot analysis, respectively. RESULTS: The HFC-A2 group showed significantly lower body weight gain and food efficiency ratio than the HFC group. BLE supplementation caused mesenteric, epididymal, and total adipose tissue weights to decrease. The serum levels of triglyceride, total cholesterol, and low-density lipoprotein cholesterol were significantly reduced, and high-density lipoprotein cholesterol was significantly increased in rats fed BLE. These results were related to lower glucose-6-phosphate dehydrogenase, acetyl-coA carboxylase, and fatty acid synthase mRNA expression, and to higher expression of the cholesterol $7{\alpha}$-hydroxylase and low density lipoprotein-receptor, as well as increased protein levels of peroxisome proliferator-activated receptor ${\alpha}$. Histological analysis of the liver revealed decreased lipid droplets in HFC rats treated with BLE. CONCLUSIONS: Supplementation of HFC with 3% or 5% BLE inhibited body fat accumulation, improved lipid profiles, and modulated lipogenesis- and cholesterol metabolism-related gene and protein expression.