• Journal of the Korea Academia-Industrial cooperation Society
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• v.7 no.6
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• pp.1308-1312
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• 2006

4-Cyano-3,5-difluorophenol, useful as intermediate in the manufacturing of liquid crystals, was prepared by the regioselective iodination of 3,5-difluorophenol to give 4-iodo-3,5-difluorophenol, which was then converted to 4-cyano-3,5-difluorophenol under a mild reaction condition. The reaction products were characterized by spectroscopic methods and confirmed by comparison of these analytical data with reported values in the literatures.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.2 no.1
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• pp.56-60
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• 2016

Benzyltrimethylammonium dichloroiodate in the presence of $ZnCl_2$ has been used for aromatic iodination of electron rich aromatic compounds. However, Baylis-Hillman type regioselective ${\alpha}$-iodination was carried out electronically rich coumarin compound under mild reaction condition with excellent chemical yield. Finally, $BBr_3$ demethylation gave ${\alpha}$-iododaphnetin.