• Asian Pacific Journal of Cancer Prevention
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• v.14 no.4
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• pp.2159-2165
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• 2013

Cancer registries help to establish and maintain cancer incidence reporting system, serve as a resource for investigation of cancer and its causes, and provide information for planning and evaluation of preventive and control programs. However, their wider role in directly enhancing oncology drug access has not been fully explored. We examined the value of cancer registries in oncology drug access in the Asia-Pacific region on three levels: (1) specific registry variable types; (2) macroscopic strategies on the national level; and (3) a regional cancer registry network. Using literature search and proceedings from an expert forum, this paper covers recent cancer registry developments in eight economies in the Asia-Pacific region - Australia, China, Hong Kong, Malaysia, Singapore, South Korea, Taiwan, and Thailand - and the ways they can contribute to oncology drug access. Specific registry variables relating to demographics, tumor characteristics, initial treatment plans, prognostic markers, risk factors, and mortality help to anticipate drug needs, identify high-priority research area and design access programs. On a national level, linking registry data with clinical, drug safety, financial, or drug utilization databases allows analyses of associations between utilization and outcomes. Concurrent efforts should also be channeled into developing and implementing data integrity and stewardship policies, and providing clear avenues to make data available. Less mature registry systems can employ modeling techniques and ad-hoc surveys while increasing coverage. Beyond local settings, a cancer registry network for the Asia-Pacific region would offer cross-learning and research opportunities that can exert leverage through the experiences and capabilities of a highly diverse region.

• Journal of the Korean Association of Geographic Information Studies
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• v.15 no.4
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• pp.26-41
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• 2012

It is necessary to manage, forecast and prepare agricultural production based on accurate and up-to-date information in order to cope with the climate change and its impacts such as global warming, floods and droughts. This study examined the applicability as well as challenges of the object-based image analysis method for developing a land cover image classification algorithm, which can support the fast thematic mapping of wide agricultural areas on a regional scale. In order to test the applicability of RapidEye's multi-temporal spectral information for differentiating agricultural land cover types, the integration of other GIS data was minimized. Under this circumstance, the land cover classification accuracy at the study area of Kimje ($1300km^2$) was 80.3%. The geometric resolution of RapidEye, 6.5m showed the possibility to derive the spatial features of agricultural land use generally cultivated on a small scale in Korea. The object-based image analysis method can realize the expert knowledge in various ways during the classification process, so that the application of spectral image information can be optimized. An additional advantage is that the already developed classification algorithm can be stored, edited with variables in detail with regard to analytical purpose, and may be applied to other images as well as other regions. However, the segmentation process, which is fundamental for the object-based image classification, often cannot be explained quantitatively. Therefore, it is necessary to draw the best results based on expert's empirical and scientific knowledge.

• Journal of the Korean Society for Railway
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• v.20 no.1
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• pp.120-127
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• 2017

The South Korean rail authority is constructing a nationwide tourism belt by developing new rail tour routes in an effort to combine local tourism resources with rail service and to create value in regional areas. As massive financial resources are required to develop and operate such tourist trains, governing authorities are required to examine the feasibility of this project as a sound business model and to assess the public benefit and profitability of the project. In this study, the economic feasibility of the tourist trains was assessed with the contingent valuation method (CVM). According to an estimation of the willingness to pay of potential tour train passengers, the surveyed subjects were willing to pay fares that were higher than prices currently published at the time of this study, thereby demonstrating that the economic value they invest on tourist trains may be higher than published prices at the time. For instance, they were willing to pay 28.4% and 54.9% more for the O-train and V-train types, respectively, according to the study, suggesting that the quality as perceived by train passengers for tourist train services is relatively high. The study is significant in that it succeeded in quantifying the satisfaction level of tourist train passengers using quantitative data (additional funds people are willing to pay).

• Journal of the Korean Institute of Landscape Architecture
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• v.43 no.5
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• pp.111-120
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• 2015

In this study, the general structure of the landscape architecture industry was considered through analysis of advertisements in the landscape architecture magazine, 'Environment & Landscape Architecture', and the transition process and factors of landscape facilities were analyzed. Based on this result, the direction of future landscape facilities and basic data were suggested. When analyzing the advertisements that have been published in 'Environment & Landscape Architecture' for 30 years, outdoor facilities were depicted at a frequency of 1,853 times and among them, rest facilities and convenience facilities were depicted 1,457 times and 378 times, respectively. The reason why outdoor facilities have a far higher advertisement frequency than other landscape facilities is they were highly influenced by the house construction-related government policy, which resulted from the expansion of the rest facility industry along with regional expansion to public design. Moreover, it was found that wood and steel were mainly used to make pergolas and benches, which are rest facilities, and polycarbonate, with high economic efficiency and durability, was used the most as a roofing material for pergolas. This study attempts to explore the tendency of landscape facilities and the changes in the detail of their types by analyzing the stream of landscape facilities diachronically, based on the advertisements published in a representative magazine of landscape architecture.

• Journal of Venture Innovation
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• v.2 no.2
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• pp.117-126
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• 2019

This study conducted correlation analysis and multiple regression analysis using financial statements, loan structure, ROA and ROA volatility of domestic commercial banks, regional banks and special banks for the past five years (2012 ~ 2016). The result is as follows. First, as a result of correlation analysis, bank's ROA is positively related to household loans and SME loans, but it is negatively correlated with the ratio of loans to large companies, sector bias, and loan loss provision ratio. Second, ROA volatility was negatively related to household loans and SME loans, but it was positively correlated with large corporate loans, sector bias ratio, and loan loss provision ratio. Third, as a result of the regression analysis, the variables that have a statistically significant effect on the ROA volatility of banks were household loans, SME loans, and large enterprise loans. From these empirical results, special banks with high volatility in profits need to diversify loan types and sectors in order to achieve business performance outside of policy finance. and Especially, Suhyup Bank and Nonghyup Bank, which have a large commercial role, have a large size per unit by focusing on short-term profit and Rather than focusing on large companies or large loans that are easy to obtain financial information, it is necessary to focus management capabilities on household loans and SME loans by developing capabilities such as screening techniques.

• Journal of Korean Society of Forest Science
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• v.97 no.5
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• pp.492-500
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• 2008

Since vegetation significantly influences on soil carbon and nutrient storage, vegetation change has been focused on terrestrial carbon and nutrient cycling studies. In this study we investigated soil carbon and major nutrient capitals at the abandoned fields, which had different vegetation composition: a three year abandoned field ($AGR_3$), two ten years abandoned fields ($PD_{10}$ dominant with Pinus densiflora and Fraxinus rhynchophylla and $PM_{10}$ dominant with Populus maximowiczii), and an over sixty years forest ($FOR_{60}$). which were located at Hongcheon-gun, Kangwon-do, South Korea. Both main effects for organic matter (%) were significant: shallow soil > deep soil and $FOR_{60}=PM_{10}$ > $AGR_3=PD_{10}$. Nitrogen concentrations at $PM_{10}$ were the highest, while the lowest at $PD_{10}$. Available phosphorus concentrations were the highest at $PD_{10}$, which were over 10 times of site $FOR_{60}$ and $AGR_3$ at 0-10 cm soil depth. The average organic matter ($173Mg\;ha^{-1}$) and nitrogen contents ($10Mg\;ha^{-1}$) of $PM_{10}$ and $FOR_{60}$ were higher than those of $AGR_3$ and $PD_{10}$ by 57% and 42%, respectively. The available phosphorus contents above 30 cm mineral soil at $PD_{10}$ ($3.8Mg\;ha^{-1}$) and $PM_{10}$ ($1.3Mg\;ha^{-1}$) were over 120 times and 40 times more than at $FOR_{60}$. Calcium ($3.7Mg\;ha^{-1}$) and magnesium contents ($2.8Mg\;ha^{-1}$) at $FOR_{60}$ were twice or three times higher than at other sites. Organic matter amounts in 0-10 cm and 10-30 em soil had significant positive relationships with nitrogen, calcium, and magnesium contents, but not available phosphorus and potassium contents. This study could not identify the effect of chronological factor and vegetation composition on soil carbon and nutrient capital owing to diverse topography as well as limited study sites. However, this study suggests the accuracy of investigation for regional carbon and nutrient sequestration can be achieved by considering the period of abandoned time on the fields and the land use types. These results may suggest the benefits of forest restoration for soil carbon and nutrient accumulation in marginal agricultural lands in South Korea.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.6
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• pp.1329-1338
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• 2015

This article aims to develop model for the right policy Tools available from the cause analysis regarding the regional differences of subway modal split in Seoul metropolitan area. This allows two major factors of the most influential subway modal split to be proved and Portfolio Analysis is conducted. The results are as follows. Firstly, the two primary factors affecting subway modal split were shown as subway adjacent area and local line bus. It signifies that expansion of subway adjacent area, establishing the number of the subway stations and increase of local line bus are required in order to improve a diminishing subway modal split. Following that, pattern of the improvement to strengthen better subway connections are classified according to the two areas which are Concentration Area of Improvement in Subway Station Area (CAISSA) and Concentration Area of Improvement in Local Bus (CAILB). Our study revealed that Ganbukgu, Seodaemungu, Geumcheongu, and Gwanakgu were selected as the area of CAILB and Songpagu, and Junggu were selected as the area of CAISSA. As all things are considered, transportation policy makers should be taken into account in the two main factors driven by our study according to types in order to enhance the future subway share proportion.

• Genomics & Informatics
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• v.8 no.4
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• pp.206-211
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• 2010

The Fas (TNF receptor superfamily, member 6) (FAS)/FAS ligand (FASLG) interaction plays a central role in the regulation of programmed cell death. FAS and FASLG polymorphisms in promoter regions affect transcriptional activities. To investigate whether FAS and FASLG polymorphisms are associated with the development and clinical phenotypes of stroke, 2 promoter single nucleotide polymorphisms (SNPs) in FAS (rs1800682, -670C/T) and FASLG (rs763110, -844C/T) were selected and genotyped by direct sequencing in 220 stroke patients [107 ischemic stroke (IS), 77 intracerebral hemorrhage (ICH), and 36 subarachnoid hemorrhage (SAH)] and 369 control subjects. For the analysis of clinical symptoms, all stroke patients were divided into 3 clinical phenotypes according to the respective results of the National Institutes of Health Stroke Survey (NIHSS) and the Modified Barthel Index (MBI) and the presence or absence of complex regional pain syndrome (CRPS). The SNPStats, SNPAnalyzer, and Helixtree programs were used to analyze the genetic data. Multiple logistic regression models (codominant, dominant, and recessive) were used to estimate odds ratios (ORs), 95% confidence intervals (CIs), and p-values. The promoter SNP rs1800682 was associated with stroke in the codominant (OR=0.48, 95% CI=0.25-0.94, p=0.04) and dominant models (OR=0.51, 95% CI=0.30-0.87, p=0.011). However, a FASLG SNP (rs763110) was not in Hardy-Weinberg equilibrium (p<0.05). In the analysis of stroke types, rs1800682 was associated with IS in the codominant (OR=0.30, 95% CI=0.12-0.74, p=0.025), dominant (OR=0.44, 95% CI=0.23-0.88, p=0.018), and recessive models (OR=0.45, 95% CI=0.21-0.99, p=0.042). The genotype frequencies of rs1800682 were different between ICH and controls in the dominant model (OR=0.49, 95% CI=0.26-0.94, p=0.031) but not between SAH and controls. In the analysis of clinical symptoms, however, rs1800682 was not related to the 3 clinical phenotypes (NIHSS, MBI, and CRPS). These results suggest that a promoter SNP (rs1800682, -670C/T) in FAS may be associated with the development of stroke in the Korean population.

• Journal of the Korean Geographical Society
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• v.40 no.5 s.110
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• pp.571-583
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• 2005

This paper presents a paleoenvironmental study on Hoya San Nicolas, a maar lake in Valle de Santiago in Central Mexican Bajio. Maar lake sediments have been widely used for high-resolution reconstruction of paleoenvironment. Many different paleoenvironmental proxy data such as stable isotopes, pollen, and sediment chemistry were produced in this study. These data help to reveal paleoenviromental changes throughout the whole period covered by sediment materials from this study site. The evidence indicates that during ca. 11,000 - ca. 8,900 cal yr B.P. there was dry climate; during ca. 8,900 - ca. 7,000 cal yr B.P. it was wetter; during ca. 7,000 - ca. 4,000 cal yr B.P. drier; during ca. 4,000 cal yr B.P - the present wetter. Prominent dominance of Pinus pollen during ca. 11,000 - ca. 8,900 cal yr B.P. and during ca. 7,000 - ca. 4,000 cal yr B.P. may reflect very low lake levels resulting in poor preservation of pollen. Pinus pollen, the most resistant pollen type, may have been able to survive severe deterioration due to arid climate, but other pollen types may not. Due to likely droughts in these periods, a sedimentation gaps are probably present in the core.

• Tuberculosis and Respiratory Diseases
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• v.43 no.4
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• pp.623-629
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• 1996

Bronchial carcinoid tumors are uncommon, constituting approximately 5% of all primary lung cancers. Carcinoid tumors belong to the calss of neuroendocrine tumors that consist of cells that can store and secrete neuramines and neuropeptides. Neuroendocrine tumors of the lung include three pathologic types : a low-grade malignancy, the so-called 'typical carcinoid', a more aggressive tumor, the "atypical carcinoid", and the most aggressive malignant neoplasm, the small-cell carcinoma. Atypical carcinoid tumor have a higher malignant potential, is more commonly peripheral than is the typical carcinoid tumor. Histologic features would characterize a carcinoid as hitologically atypical : increased mitotic activity, pleomorphism and irregularity of neuclei with promonent nucleoli, hyperchromatin, and abnormal nuclear-cytoplasmic ratio, areas of increased cellularity with disorganization of architecture, and areas of tumor necrosis. Metastatic involvement of regional lymph nodes and distant organ is common. The prognosis is related to size of the tumor, typical of atypical appearance, endoluminal of extraluminal growth, vascular invasion, node metastasis, Pulmonary resection is the treatement of choice for bronchial carcinoid. We experienced one case of bronchopulmonary atypical carcinoid tumor. In the case, radiologic study showed solitary lung mass with liver metastasis and the level of 5-HIAA was elevated. There was no history of cutaneous flushing, diarrhea, valvular heart disease. The authors reported a case of bronchopulmonary atypical carcinoid tumor with review of literatures.