• Economic and Environmental Geology
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• v.33 no.2
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• pp.117-128
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• 2000

Regional evaluations of slope stability by the failure criterion and by environmental geological factors were conducted. The failure criterion is the general conditions for plane failure which consider the geometrical conditions between geological discontinuities and topographical slope planes. The factor focused in this condiction is dip and dip direction. Geostatics, named semivariogram was used for establishing structural domains in slope stability evaluation by the failure criterion. The influential range was calculated to 6 km in the case of dip direction of dominant joint set and 7 km in the case of dip of the same dominant joint set. Then applying this failure criterion to the study area produced a slope stability map using the established domains and slopes generated by TIN module of ARC/INFO GIS. This study considered another regional slope stability analysis. 5 failure-driven factors 9the unstable slope map, geology, engineering soil, groundwater, and lineament density) were selected and used as data coverages for regional slope stability evaluation by geoenvironmental factors. These factors were weighted and overlayed in GIS. From the graph of cumulatave area (%) and instability index, finding critical points classified the instability indices. The most unstable slopes are located in the southern area of Mt. Eorae, Dabul-ri, and the eastern area of Junkok-ri in the first area is plane failure. Also, the expected orientations of failure are 59/338 and 86/090 (dip/dip direction).

• Radiation Oncology Journal
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• v.37 no.1
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• pp.51-59
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• 2019

Purpose: We evaluated failure pattern and treatment outcomes of observational approach on regional lymph node (LN) in cutaneous melanoma of extremities and sought to find clinico-pathologic factors related to LN metastases. Material and Methods: We retrospectively reviewed 73 patients with cutaneous melanoma of extremities between 2005 and 2016. If preoperative 18-F-fluorodeoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) findings were non-specific for regional LNs, surgical resection of primary tumors with adequate margins was performed without sentinel lymph node biopsy (SLNB) and/or complete lymph node dissection (CLND), irrespective of tumor thickness or size. In patients with suspicious or positive findings on PET/CT or CT, SLNB followed by CLND or CLND was performed at the discretion of the surgeon. We defined LN dissection (LND) as SLNB and/or CLND. Results: With a median follow-up of 38 months (range, 6 to 138 months), the dominant pattern of failure was regional failure (17 of total 23 events, 74%) in the observation group (n = 56). Pathologic LN metastases were significant factor for poor regional failure-free survival (hazard ration [HR] = 3.21; 95% confidence interval [CI], 1.03-10.33; p = 0.044) and overall survival (HR = 3.62; 95% CI, 1.02-12.94; p = 0.047) in multivariate analysis. In subgroup analysis for cN0 patients according to the preoperative PET/CT findings, LND group showed the better trend of LRFFS (log rank test, p = 0.192) and RFFS (p = 0.310), although which is not statistically significant. Conclusion: Observational approach on regional LNs on the basis of the PET/CT in patients with cutaneous melanoma of extremities showed the dominant regional failure pattern compared to upfront LND approach. To reveal regional lymph node status, SLND for cN0 patients may of importance in managing cutaneous melanoma patients.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.4
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• pp.1630-1642
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• 2016

Inter-domain routing is the most critical function of the Internet. The routing system is a logical network relying on the physical infrastructure with geographical characteristics. Nature disasters or disruptive accidents such as earthquakes, cable cuts and power outages could cause regional failures which fail down geographically co-located network nodes and links, therefore, affect the resilience of inter-domain routing system. This paper presents a model for regional failures in inter-domain routing system called REFER for the first time. Based on REFER, the resilience of the inter-domain routing system could be evaluated on a finer level of the Internet, considering different routing policies of intra-domain and inter-domain routing systems. Under this model, we perform simulations on an empirical topology of the Internet with geographical characteristics to simulate a regional failure locating at a city with important IXP (Internet eXchange Point). Results indicate that the Internet is robust under a city-level regional failure. The reachability is almost the same after the failure, and the reroutings occur at the edge of the Internet, hardly affecting the core of inter-domain routing system.

• Radiation Oncology Journal
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• v.35 no.4
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• pp.359-367
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• 2017

Purpose: This study sought to identify potential candidates for adjuvant radiotherapy and patterns of regional failure in patients who underwent curative-intent surgery for gallbladder cancer. Materials and Methods: Records for 70 patients with gallbladder cancer who underwent curative resection at a single institution between 2000 and 2016 were analysed retrospectively. No patients received adjuvant radiotherapy. Initial patterns of failure were evaluated. Regional recurrence was categorized according to the definitions of lymph node stations suggested by the Japanese Society of Hepato-Biliary-Pancreatic Surgery. Results: Median follow-up was 23 months. Locoregional recurrence as any component of first failure occurred in 29 patients (41.4%), with isolated locoregional recurrence in 13 (18.6%). Regional recurrence occurred in 23 patients, and 77 regional recurrences were identified. Commonly involved regional stations were #13, #12a2, #12p2, #12b2, #16a2, #16b1, #9, and #8. Independent prognostic factors for locoregional recurrence were ${\geq}pT2$ disease (hazard ratio [HR], 5.510; 95% confidence interval [CI], 1.260-24.094; p = 0.023) and R1 resection (HR, 6.981; 95% CI, 2.378-20.491; p < 0.001). Conclusion: Patients with pT2 disease or R1 resection after curative surgery for gallbladder cancer may benefit from adjuvant radiotherapy. Our findings on regional recurrence may help physicians construct a target volume for adjuvant radiotherapy.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.398.3-399
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• 2002

Quality control by analytical ability with a certain level of precision and accuracy is important. This is true especially in pharmaceutical industries. for a failure in quality control can result in a failure in drug medication. in turn. sometimes a heavy damage to patient's health condition andlor the worst damage to company's reputation. On this backgroun, Kyungki KFDA prepared test pharmaceutical products, which were distributed to 114 pharmaceutical companies in kyungin Province in year 2000. (omitted)

• Radiation Oncology Journal
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• v.36 no.4
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• pp.304-316
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• 2018

Purpose: The indication of elective neck treatment (ENT) for clinically N0 (cN0) paranasal sinus (PNS) carcinoma remains unclear. We aimed to investigate different treatment outcomes regarding ENT and propose optimal recommendations for ENT. Materials and Methods: We identified patients with cN0 PNS carcinoma who underwent curative-intent treatment between 1992 and 2015. Survival outcomes and pattern of failure were compared between patients who received ENT and those who did not. We sought to identify significant patient or pathologic factors regarding treatment outcomes. Results: Among 124 patients meeting the inclusion criteria, 40 (32%) received ENT ('ENT (+) group') and 84 (68%) did not ('ENT (-) group'). With a median follow-up of 54 months, the 5-year overall survival (OS) was 67%, and the 5-year progression-free survival (PFS) was 45%. There was no significant difference between the ENT (+) and ENT (-) groups regarding OS (p = 0.67) and PFS (p = 0.50). Neither group showed a significantly different pattern of failure, including regional failure (p = 0.91). There was no specific benefit, even in the subgroups analysis by tumor site, histologic type, and T stage. Nevertheless, patients who ever had regional and/or distant failure showed significantly worse prognosis. Conclusion: ENT did not significantly affect the survival outcome or pattern of failure in patients with cN0 PNS carcinomas, showing that ENT should not be generalized in this group. However, further discussion on the optimal strategy for ENT should continue because of the non-negligible regional failure rates and significantly worse prognosis after regional failure events.

• Journal of Communications and Networks
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• v.16 no.5
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• pp.534-547
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• 2014

Large-scale failures resulting from natural disasters or intentional attacks are now causing serious concerns for communication network infrastructure, as the impact of large-scale network connection disruptions may cause significant costs for service providers and subscribers. In this paper, we propose a new framework for the analysis and prevention of network service disruptions in large-scale failure scenarios. We build dynamic deterministic and probabilistic models to capture the impact of regional failures as they evolve with time. A probabilistic failure model is proposed based on wave energy behaviour. Then, we develop a novel approach for preventive protection of the network in such probabilistic large-scale failure scenarios. We show that our method significantly improves uninterrupted delivery of data in the network and reduces service disruption times in large-scale regional failure scenarios.

• Journal of the Korean Geosynthetics Society
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• v.17 no.4
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• pp.11-19
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• 2018

Although many researches related to monitoring and automatic measuring devices for early warning system during slope failure have been carried out in Korea and aboard, most of the researches have installed measuring devices on the slope surface, and there are only few researches about warning systems that can detect and warn before slope failure and disaster occurs. In this study, slope failure simulation experiment was performed by attaching sensors to rock bolts, and initial slope behavior characteristics during slope failure were analyzed. Also, the experiment results were compared and reviewed with varied slope conditions, i.e. shotcrete slope and natural slope, and varied material conditions, i.e. GFRP and steel rock bolt. This study can be used as a basic data in development of warning and alarm system for early evacuation through early detection and warning before slope failure occurs in steep slopes and slope failure vulnerable areas.

• Korean Journal of Head & Neck Oncology
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• v.21 no.1
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• pp.26-31
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• 2005

Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.

• Journal of the Korean GEO-environmental Society
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• v.19 no.9
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• pp.29-36
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• 2018

Several studies have been conducted on monitoring system and automatic measuring instruments to prevent slope failure in advance in Korea and overseas. However, these studies have quite complex structure. Since most of the measurement systems are installed on the slope surface, the researches are carried on the measurement system that detects sign of slope collapse in advance and alerts are still unsatisfactory. In this study, slope collapse experiments were carried out to understand the slope failure mechanism according to rainfall conditions. The water content and displacement behavior at the early stage of the slope failure were analyzed through the measurement of the ground displacement and water content. The results of this study can be used by local government as a basic data for the design of slope failure alarm system to evacuate residents in case of slope failure or landslide due to heavy rainfall.