• Korean Institute of Interior Design Journal
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• no.27
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• pp.96-103
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• 2001

The purpose of this thesis is to study on the source, the introductive process and the phenomenon of the regional tendency into Korean modern interior design. To achieve the purpose of this study, the methods and contents are as follows : 1. Explaining the regionalism in the architecture as the source of the regional tendency. 2. Explaining the introductive process of the regional tendency in Korean modern interior design.. For that, 1)Explaining the traditional expression, the leo-corbusian expression and the organic expression with nature in Korean contemporary architecture 2)Explaining the vernacular expression and the abstract expression in Korean modern art 3. Studying the regional tendency in Korean modern interior design For that, 1)Studying the expression of Korean traditionality 2)Studying the expression of the vernacular 3)Studying the expression of the environmental affinity By theme methods and contents, we will study the introduction of the regional tendency into Korean modern interior design.

• Korean Institute of Interior Design Journal
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• no.22
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• pp.77-84
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• 2000

The study aims at looking, into conceptual transfer of environment between Minimal Art and Minimalism architecture and analysing architectural expressional characteristics which could visually show pro-environmental expression from concept of environment-orientation in the architecture in regional minimalism. This study issued the survey of Minimalism architecture as newly architectural trend since Late-Modernism, and pro-environment as important paradigm in the near future. In this analyses, the characteristics of pro-environmental expression can be classified as follow ; a the brightness and darkness of light, b. the perspective view of simplified wall, c. the visualization of environmental characteristics, d. the transparency and reflectiveness of glass, e. the all direction of cube, f. the visual division of architecture. These show that symbolized variety implying expression variety and implying Oriental view of nature were expressed as unique language of regional Minimalism architecture, by visual simplicity as characteristics of Minimalism and Occidental Modernism as motive of Minimalism.

• Journal of the Korean Institute of Rural Architecture
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• v.17 no.2
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• pp.43-50
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• 2015

The purpose of this study is to examine application possibility as the inhabitants educational program for community design workshops of regional linking cooperation project "Sejong healing road 100 project". As a results follows : First, It can confirm inhabitants ability reinforcement through administration of the 8-week educational program, and a participation rate is important in it. Second, 'The tool of inhabitants opinion expression using a Post-it' is easy as a tool of the workshops, and the effect improves if It use a drawing together. Third, 'The tool of inhabitants opinion expression using figure card' is the most effective as expression of the inhabitants intention as a tool of the workshops, but preparations process is complicated. Moreover, for the inhabitants participation in regional linking cooperation projects, the development system of a more systematic inhabitants intention expression is necessary.

• Journal of the Regional Association of Architectural Institute of Korea
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• v.21 no.6
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• pp.119-128
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• 2019

The aim of this study is to examine the characteristics of facade expression designed by Kim. Han-sup, a key architect in the regional modern architecture movement in Gwang-ju and Jeonnam from the 1950's to 1960's. The study begins with the architectural background and thoughts of Kim. Han-sup through literature reviews and introduces an interview with Han. chong-un, a former college student and employee of Kim, which explains the aesthetic architecture that appeared in his design of facades that was reasonably applied to materials, technology, structure and function in line with the economically tough period in Korea. Furthermore, in order to investigate the characteristics of his facade expression, detailed analysis items will be derived from precedent studies. This study will attempt to conclude with statements that his aesthetic architecture can be defined as an emphasis on formative mass by contrasting between basic rectangular forms, implementation with detailed three-dimensional facade by extruding differently vertical and horizontal structural lines and with the pursuit of decoration through compartmental faces on his 12 representative architectural works.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.33 no.3
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• pp.199-203
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• 2007

Several matrix metalloproteinases (MMPs) have been shown to play an important role in the invasion and metastasis of oral squamous cell carcinoma (OSCC). The members of the TGF-$\beta$ signaling pathway are being considered as predictive biomarkers for progressive tumorigenesis and molecular targets for the prevention and the treatment of cancer and metastasis. The aim of the present study was to find the clinical significance of the expression of TGF-${\beta}1$ and MMP-2 related to the regional lymph node metastasis in OSCC. This study included 76 cases of primary OSCC, of which 42 cases showed regional lymph node metastases. Immunohistochemistry was used for the localization of protein. The relation between the expression of each protein and clinical variables was statistically evaluated. In results, the expression of TGF-${\beta}1$ both main mass with lymph node metastasis and without lymph node metastasis was found not to be statistically significant (p>0.05). The expression of MMP-2 was found to be statistically significant related to regional lymph node metastasis (p<0.05). When compared the expression in the metastatic lymph node, TGF-${\beta}1$ was significantly highly expressed than MMP-2 (p<0.05). In conclusion, the expression of MMP-2 was significantly elevated in patients with lymph node metastasis as compared to the patients without lymph node metastasis, which could be useful in predicting the risk of lymph node metastasis in OSCC.

• Microbiology and Biotechnology Letters
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• v.41 no.2
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• pp.253-262
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• 2013

In this study, we analyzed the anti-oxidative and anti-inflammatory activities of seven medicinal herbs. All extracts of the tested herbs, Euryale ferox Salisbury, Echinops setifer Iljin, Amomum cardamomum Linne, Tetrapanax papyriferus, Illicium verum Hook. f., Typha orientalis Presl, and Piper longum Linne, exhibited potent anti-oxidative activity as confirmed by DPPH radical scavenging capacity. Lipopolysaccharide (LPS) induced nitric oxide (NO) production, in the RAW 264.7 cell line, was also ameliorated by all extracts' treatments in a dose dependent manner. NO suppressive activity originated from the inhibition of inducible nitric oxide synthase (iNOS) protein expression by the extracts. Three extracts, E. ferox S., I. verum Hook. f., and P. longum L., possessed suppressive activity against, not only iNOS, but also cycloxygenase 2 (COX-2) protein expression. These three extracts may then serve as potential candidates for non steroidal analgesic inflammation drugs (NSAIDs). Furthermore, all extracts induced anti-oxidative enzyme, heme oxygenase 1, protein expression. Taken together, these results provide an important new insight into the fact that various medicinal herbs possess potent anti-oxidative and anti-inflammatory activities and might be utilized as promising agents in the field of health products. Further studies for the identification of the active compounds from medicinal herbs are clearly needed.

• Asian-Australasian Journal of Animal Sciences
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• v.19 no.10
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• pp.1508-1513
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• 2006

Myostatin (MSTN) and insulin-like growth factors (IGFs) are a known inhibitor and stimulators of proliferation and differentiation of muscle cells, respectively. The present study was performed to investigate the relationship of MSTN-induced growth inhibition to expression of the IGF system components and myogenin, a muscle cell-specific transcription factor, in rat L6 myoblasts. The L6 cells transfected with a green fluorescent protein-MSTN plasmid expression construct had a 47% less cell number than mock-transfected cells after 3-d serum-free culture, accompanied by delayed differentiation which was suggested by inhibited aggregation of cells. Moreover, cells transfected with the expression construct had decreased expression of IGF-II and myogenin genes, but not IGF-I or its receptor genes, as examined by reverse transcription-polymerase chain reaction. The reduced mitosis of the L6 cells transfected with the MSTN-expression construct increased following an addition of either IGF-I or IGF-II to the culture medium, but not to the level of mock-transfected cells. By contrast, myogenin gene expression in these cells increased after the addition of either IGF to the level of mock-transfected cells. Collectively, these results suggest that the inhibitory effect of MSTN on L6 cell proliferation and differentiation is likely to be partly mediated by serially suppressed expression of IGF-II and myogenin genes, not IGF-I gene.

• Archives of design research
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• v.16 no.4
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• pp.267-276
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• 2003

In these days, each local administrative organizations and residents have made constant efforts to achieve unique regional identity and its publicity as a strategy for 'Place Marketing'. Developing a proper symbolic regional theme for the area can bring the economic and cultural vitality to the local areas. The purpose of this study is to investigate and to analyze the contents of theme and expression methods of local theme museums of Japan for last 20years. The types of regional themes appeared as 'Physical' part like topography/ecology, relics and manmade facilities, and 'Social ＆ Cultural' part like industry, culture, people or historic events. The cases of expression methods such as Representation, Metaphor, Symbol and Metonymy could be also found. There was an increasing tendency applying and expressing the symbolic regional theme more impressively as the time passed.

• Korean Institute of Interior Design Journal
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• v.15 no.1 s.54
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• pp.63-70
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• 2006

This study investigates and analyzes natural traits in Gaudi's architectural designs on the assumption that the naturalism in his architectural designs has been built heavily on regional cultural background. In particular, focusing on four buildings Gaudi designed in his late years, this study distinguishes between natural traits found in ornaments and details, and natural traits as organic expression of form. This study shows, first, with regard to natural traits in ornaments and details, organic motives were applied to patterns, plastic objects, and parts of the building. Second, natural traits in organic expression of form were reflected by typifying $Catalu\tilde{n}a$ regional nature, using curved lines of organic shapes and realizing lively natural creatures. It is remarkable that Gaudi developed his architectural designs as unique magic naturalism based on his imagination. And In this century 'Regional Culture' gets more important in architectural designs. Gaudi's architectural works can be appreciated to represent very well $Catalu\tilde{n}a$ regional cultural identity by using properly its natural motives and objects.

• The Journal of the Korea Contents Association
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• v.11 no.7
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• pp.131-141
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• 2011

Expression of color in national animation often delivered vaguely. This study will make up for vaguely meaning in terms of expression in color. And this study is intend to look the strategy and error of color in regional animation. This study is intend to arrange the situation of synesthesia effect of color which is applied as a keyword 'light' of Gwang-ju's image. Moreover, There is a bit difficulty in using synesthesia of color, but the use possibility is full of suggestions. Therefore, For regional animation, this study intend that in order to establish a new regional specialized animation, appropriateness of synesthesia effect of color in based animation is inspected and then the potential is emphasized.