• Journal of the Korean association of regional geographers
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• v.23 no.2
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• pp.239-256
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• 2017

This research is a theoretically grounded empirical study aimed at shedding light on the policy evolution of Technology Park(TP) in term of historical institutionalism in South Korea for the 16 years. The study analysed the evolution of TP, and the empirical fieldwork was completed in two regions, Gyeongsangbuk-do ana Daegu City. Historically the policy can be divided into three periods being affected by endogenous and exogenous impact. This research found that the functions of local TPs changed as following: six functions decided by central governments ${\rightarrow}$ added the role of supporting regional innovation ${\rightarrow}$ comprehensive support for small & medium-sized enterprise. Analysis of the empirical study reveals significant findings: first, the relationships between central government and local actors which was built in the quickening period have been path dependency. Second, the functions of local TPs were evolved with the characteristics of layering and reorientation of the institutions. Thirdly, there were some differentiation between the two regions because of the milieu, though the central government had the power deciding the functions.

• Microbiology and Biotechnology Letters
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• v.42 no.4
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• pp.354-360
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• 2014

In this study, the anti-obesity activity of Smilax china methanol extract (SCME) was evaluated using a pancreatic lipase enzyme inhibition assay, and a cell culture model system. Results indicated that, SCME effectively inhibited pancreatic lipase enzyme activity in a dose-dependent manner. Furthermore, SCME significantly suppressed insulin, dexamethasone, 3-isobutyl-1-methylxanthine-induced adipocyte differentiation, lipid accumulation, and triglyceride contents on 3T3-L1 preadipocytes, in a dose-dependent manner. The anti-adipogenic effect was modulated by cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins (C/EBP) ${\alpha}$, $C/EBP{\beta}$, and the peroxisome proliferator-activated receptor ${\gamma}$ gene and protein expressions. Moreover, SCME triggered lipolysis effects dose-dependently on adipocyte. Taken together, these results provide an important new insight into SCME, indicating that it possesses anti-obesity activity through pancreatic lipase inhibition, anti-adipogenic and lipolysis effects. SCME may therefore be utilized as a promising source in the field of nutraceuticals. The identification of active compounds that confer the anti-obesity activities of SCME may be a logical next step.

• Microbiology and Biotechnology Letters
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• v.43 no.4
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• pp.336-342
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• 2015

Previously, Euptelea pleiosperma was identified as one of the useful sources containing anti-oxidative and anti-inflammatory activities for the first time in our research group. In this study, anti-obesity effect of E. pleiosperma ethanol extract (EPEE) was evaluated by using a pancreatic lipase enzyme inhibition assay and a cell culture model system. EPEE suppressed effectively pancreatic lipase enzyme activity dose dependently. Furthermore, EPEE significantly suppressed adipocyte differentiation, lipid accumulation, triglyceride contents, and triggered lipolysis activity on 3T3-L1 preadipocytes in a dose-dependent manner without cytotoxicity. Anti-adipogenic effect of EPEE was modulated by cytidine-cytidine-adenosine-adenosine-thymidine (CCAAT)/enhancer binding proteins ${\alpha}(C/EBP{\alpha})$, $C/EBP{\beta}$ and peroxisome proliferator-activated receptor ${\gamma}(PPAR{\gamma})$ gene and protein expressions. Taken together, these results provide the important new insight that E. pleiosperma possesses anti-obesity activities such as pancreatic lipase inhibition, anti-adipogenic, and lipolysis effects. It might be utilized as promising sources in the fields of nutraceuticals. The identification of active compounds that confer anti-obesity activity of EPEE might be needed.

• Journal of Digital Convergence
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• v.11 no.12
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• pp.735-745
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• 2013

Tour industry has been growing with increasing of people leisure time quantitatively as well as qualitatively. Especially, region tourist industry shows rapid growth because of the development of transportation and communication. Tourist contents that representing the region have been developing briskly. However there are many nominal tourist contents have just region differentiation with same attribute and composition. It has to be consider about tourist first not a contents provider or a developer. To be memorable tourist contents and to connect to consumption, understanding about tourist is needed. So 'Experience' will be standards when tourist contents is planned. In that sense, experience 4factors from Experience Economy and Challenge-skill model from Flow will be frames for giving shape to develop tourist contents. Experience 4factors from Experience Economy suggests 4factors for the superb enjoyment to tourists, and Challenge-skill model from Flow proposes balanced contents for understanding tourists. They will contribute to suggest planning frames for sustainable tourist contents and it lead to tourists' reinstation.

• Journal of the Korean Society of Clothing and Textiles
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• v.26 no.1
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• pp.168-178
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• 2002

This study is aimed at investigating and comparing the differences in the uniform of nurses according to regions and hospital size in Korea. This study takes two large regions as its survey area; one is Seoul, Incheon and Gyeonggi Province, and the other is Daejon and Chungcheong Province. The hospital size is divided into general hospitals and neighborhood hospitals. The survey was conducted among the nurses working in 12 randomly-selected hospitals and its statistical results are analysed firm 818 respondents'questionnaires. The results are divided into 3 categories as follows; 1) Results of analysis of survey on the uniform of nurses : Nurses usually wear two-piece suits and more than half of the hospitals choose a white-color pattern. And the nurse's uniform with color varying according to their position and ward is considered to be desirable; 2) Analysis on regional differences : In the case of Daejon and Chungcheong Province, there is a relatively high ratio of respondents who answered questions with 'high percentage of young nurses', 'position differentiation by means of different design and fabric according to ward'. In case of Seoul, Incheon and Gyeonggi Province, questions with 'use of a patterned textile in nurses'uniform', 'ready-made size system'are higher; 3) Analysis of the differences in accordance with hospital size : In the case of general hospitals, there is relatively a high ratio of respondents who answered questions with 'use of different design and fabric according to a nurse's position', 'use of patterns in nurses'uniform'. In the case of neighborhood hospitals, there is a high ratio of respondents with'use of classical one-piece or two-piece type wear', 'ready-made type size system', 'obligatory use off nurse's cap'.

• Journal of the Korean association of regional geographers
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• v.19 no.2
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• pp.203-222
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• 2013

This study has been implemented under the two purposes. One is to critically explore how married immigrant women had experienced or experience conflicts, differentiation and so on occurred in their relations to family, neighbor, friend, organization and nation. The other is to understand married immigrant women and family through a new perspective based on a relational space of interacting trans-nation, local and nation. The results of the study are summarized as the followings. Firstly, transnational space is produced by international marriage between Korean man and foreign woman and kept (or activated ) by (non) everyday activities of married immigrant women and family. There are remittance, children's rearing and education, visits to mother's house, emotional interactions by phone and computer and so on. Secondly, multi-layered and relational local spaces have been (re)produced by married immigrant women's various activities related to family, neighbor, friend, nation and so on. Thirdly, married immigrant women's relations to nation state or government has been specifically presented (or expressed) through the acquiring of Korean nationality and government's activities of supporting multicultural family. Married immigrant women feel that their national identity between mother's nation and Korea is ambiguous and undecided.

• Journal of Gastric Cancer
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• v.3 no.1
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• pp.33-37
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• 2003

Purpose: Alpha-fetoprotein (AFP) is widely accepted as a useful tumor marker for diagnosis of hepatocellular carcinomas. On rare occasions, however, an abnormal elevation of serum AFP also has been reported in an adenocarcinoma of the gastrointestinal tract. We evaluated the influence of preoperative abnormal elevation of serum AFP (AFP positivity) on the prognosis of resectable gastric cancers. Materials and Methods: 812 gastric cancer patients, who were investigated for serum AFP before their operations and who underwent gastric resections with D2 or more extended lymph node dissection, were enrolled in the study. The survival rates were calculated by using the Kaplan-Meier method and were compared by using the log-rank test. A multivariate analysis was performed using the Cox proportional hazards model. Results: Fifty patients ($6.2\%$) were AFP positive (10.1. 4322.6 ng/ml). The survival rate of the AFP positive group was significantly lower than that of the AFP negative group ( $46.6\%\;vs.\;67.0\%$; P=0.0002). The depth of tumor invasion, the degree of regional lymph node metastasis, distant metastases, the TNM stage, the gross type, differentiation, the extent of gastric resection, and the curability of the surgery also significantly influenced survival. Multivariate analysis revealed that the depth of tumor invasion, the degree of regional lymph node metastasis, the curability of the surgery, and AFP positivity were independent prognostic indicators. Conclusion: Preoperative serum AFP can be used as an independent prognostic factor of resectable gastric cancer.

• Journal of the Korean association of regional geographers
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• v.9 no.3
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• pp.262-275
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• 2003

In this study, the characteristics of locational distribution of the eminent people show their socially and economically stabilized standing in Daegu, taking the aforesaid situation as a background of the study, and the process of this study is as follows ; to examine the forming process of residential areas in the city as a theoretical supporting, to put in order on classical interpretation to formation of residential areas, and general type modem residential areas formation, and economic decision factor of land use. Therefore, this study aims to examine growth and development of eminent persons' residential areas and, at the same time, extract locational characteristics through the pattern of eminent persons' location and predict changes in the future. Furthermore, a long-term development plan of Daegu is expected to contribute to completing formation of sub-centers as well as expanding metropolis areas. Recent efforts by the city government such as the ones to attract prestigious high schools in the upper city areas are also expected to bring out balanced development of the city.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2442-2449
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• 2015

The purpose of this paper is to examine the effects of Human Resources Development by type and strategy, and to review the importance of Human resources Development in the knowledge-based society in a comprehensive way. In particular, the paper reviews the tourism industry, one of the typical service industry, for which the utilization of the Human Resources is crucial. and it presents a specific direction policy of Human Resources Development in the field. An analysis was performed for each area of Human Resources Development inputs and output factors which lead to achieve the purpose of the study was to review the characteristics of the Human Resources Development area. After reviewing, the tourism industry was differentiated according to type of strategy development areas through a statistical approach to the input and output elements around. In this study, along with the estabilishment of a Human Resources development strategy bases on the nature and purpose of differentiation with future Human resource Development in each region showed that the operations of the business need.

• Journal of the Korea Convergence Society
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• v.8 no.7
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• pp.39-46
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• 2017

Dongguan City of Guangdong province, one of the core areas of the Pearl River Delta, has also pursued economic development through the geographical advantage close to Hong Kong. In the early 1980s, small and medium-sized multinational corporations related to home appliances industry from Hong Kong invested to the Dongguan area and set up a production factory. In the mid-1990s, as Taiwanese PC manufacturers invested, local industrial clusters have developed in Dongguan with core of the IT, PC components and electronic industries. The case of the IT industrial cluster in Dongguan is a typical example of the development of Chinese manufacturing industry after the reform of China. This paper focused on the coupling strategy case of Dongguan City industrial cluster in Guangdong province, and theoretically compared the endogenous growth factor analysis(NMID) of regional industrial development with the regional differentiation of industry based on external linkage with global production network(GPN).