• 한국지반공학회논문집
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• 제24권5호
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• pp.107-115
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• 2008

본 연구는 1차압밀 중의 크리프의 영향과 Yin이 제안한 탄-점-소성 모델에 대한 적용성을 검토하였다. 탄성모델을 이용한 일반적인 압밀이론은, 1차압밀 과정을 표현할 수 있으나 2차압밀을 표현할 수 없다. 이러한 결과는 2차압축을 표현할 수 있는 점성에 기인하며, 때로는 Ladd 등(1977)이 제안한 가정 A 및 B와 같은 스케일효과(실험실 공시체와 현장조건 사이의 점토층 두께의 차이)와 관련되어진다. 통상적으로 1차압밀 중의 크리프의 존재는 많은 연구자에 의해 확인되어졌으며, 가정 B가 잘 맞는 것으로 되어있다. 한편, 대형압밀시험을 통해 가정 A와 B의 중간적인 특성이 Aboshi(1973)에 의한 가정 C로써 제안되어졌다. 본 연구에서는 1차압밀 중의 침하-시간관계에 대한 크리프의 영향을 명백히 하기 위해, peat와 점토에 대해 분할형 압밀시험기를 이용하여 가정 B의 압밀시험을 행하였다. 그리고 Yin의 탄-점-소성 모델을 이용하여 실험결과를 해석하였다. 얻어진 결과는 다음과 같다. 1차압밀 종료시에 분할 공시체의 압축은 과잉간극수압 소산속도의 차이에 의해 동일하지 않았다. 또한 분할형 압밀시험기에 의해 측정된 평균변형률과 Yin의 EVP 모델을 이용한 해석치는 잘 일치하였다. 그러나 과잉간극수압의 소산에 대해서는 측정치가 Yin 모델에 비해 빨리 소산되었다.

• 벤처혁신연구
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• 제7권2호
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• pp.1-17
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• 2024

본 연구는 기업의 산업단지의 입주 여부에 따른 혁신·경영성과에 미치는 영향을 분석하는데 목적이 있으며, 특히 수도권과 비도권의 지역별 차이에 따른 산업단지의 입주효과를 비교·분석하였다. 가설검증을 위해 과학기술정책연구원에서 제공하는 2022년 한국기업혁신조사(제조업)를 활용하였다. 분석방법으로 회귀분석(OLS 및 Probit)을 통해 변수간 영향관계에 대한 유의성을 검정하고, 집단을 구분하는 과정에서 발생하는 선발편의를 최소화하고자 성향점수매칭(PSM)을 활용하였다. 분석결과, 첫째, 혁신성과의 경우 산업단지에 입주한 기업이 비입주 기업에 비해 혁신성과에 긍정적 영향을 미치는 것으로 나타났다. 둘째, 경영성과의 경우 입주기업과 비입주 기업 간 차이는 통계적으로 유의하지 않은 것으로 분석되었다. 셋째, 지역적 변수를 고려한 경우, 수도권에 소재한 산업단지에 입주한 기업은 비입주 기업에 비해 혁신성과에 긍정적 영향을 미쳤으나 경영성과에는 통계적으로 유의하지 않은 것으로 나타났다. 반면, 비수도권에 소재한 산업단지의 경우 혁신성과 및 경영성과에 모두 통계적으로 유의하지 않는 것으로 분석되었다. 이러한 분석결과를 토대로 입주기업에 대한 사후관리 방안 제시, 기업 유치 과정에 따른 다각적이며 전략적 게획 수립의 필요성 등의 정책적 함의를 논의하였다.

• 한국학교보건학회지
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• 제2권1호
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• pp.108-130
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• 1989

The purpose of this study is to provide the basic data for the development of school health nursing activities by surveying realities of school health nursing activities in schools lacking in a school nurse performed by teachers holding additional school health. The subjects for the study was selected from teachers holding additional school health who participated in the annual training course for teachers holding additional school health in 1988 organized by Province Education Council. 105 teachers holding additonal school health from Kyung-gi Province, 85 from Chung-buk province, 50 from Chun-buk Province, answered the questionaire. The results can be epitomized as follows. 1. General characteristics of Teachers Holding Additional School Health. The majority of the subjects are female (94.3%) and 64.1% of the subjects are in their twenties, 79.5% of them graduated from four-year teacher's college, 54.5% of them are unmarried, 74.5% has less than one-year experience as a teacher holding additional school health. 2. General characteristics of schools 92.4% of schools are national, of public schools, and 91.9% are located in country, elementary schools are 64%, junior high schools are 35.4%. The annual school nursing budget is unknow to 89.2% of them. The school nursing organization is non- existent to 85.6%. 82.4% of the school nursing clinics occupy their place solely, or jointly. 3. Status of School Health Nursing Activities In the questionaire, School Health Nursing Activities arc divided into Health Program planning and Evaluation (4 items), Clinic Management (4 items), Health Education (4 items), Management of School Environment 98 items), Operating of School Health Organization (1 item) and Health Care Service (25 items). The answers to each item measured by the Likert-type scale reveals that in the activities of techcrs holding additional school health the practice rate in Management of School Environment is 55%, 47% in Health Education, 45% in Health Program Planning and Evaluation, 32% in Health Care Service, 27% in Operating of School Health Organization, and 27% in Clinic Management. 4. The Relation between Influencing variables and School Health Nursing Activities. The results are as follows. (1) Health Program Planning and Evaluation: religion, marital status ($P<0.05^{**}$) (2) Clinic Management: age, school health organization ($P<0.05^{**}$) (3) Health Education: age ($P<0.01^*$), religion ($P<0.05^{**}$), business except for school nursing ($P<0.05^{**}$), form of operation ($P<0.05^{**}$), the number of clinic client a month ($P<0.05^{**}$). (4) Management of School Health Environment: age, marital status, business except for school nursing ($P<0.05^{**}$), presence of the annual school health nursing budget ($P<0.01^*$), school health organization ($P<0.05^{**}$). (5) Operating of School Health Organization: There is a statistical significance in Education, Interest in School Nursing ($P<0.05^{**}$). 5. The Regional Relationship of School Health Nursing Activity. There is a statistically significal difference in Health Education ($P<0.05^{**}$) and Health Care Service ($P<0.01^*$) of elementary school located in Kyung-gi, Chung-buk, Chun-buk Province. There is a statistically significant difference Health Program Planning and Evaluation of junior high Schools located in Kyung-gi, Chung-buk, Province ($P<0.05^{**}$). 6. The Correlation in School Health Nursing Activities. The analysis of the correlation in the 6 fields of school Health Nursng Activities shows that there is a statistically significant difference between Clinic Management and health Education, Clinic Management and Operating of School Health Organization, and between management of School Environment and operating of School Health Organization ($P<0.05^{**}$). The conclusions are as follows The 40.5 percent of schools should arrange nurse teachers by regulation 38, relative to the application of the Law of Education. But, in reality, teachers who have nothing to do with nursing, hold school health as an additional job. And it is very difficult to expect the qualititive health management of school faculty and students. In the 85.6 percent of schools, there is no organization for school health. And also, persons in charge of pracitcal affairs perform the school health activity without any knowledge about annual school health nursing budget. In the school health nursing activity of teacheres holding additional school health, operating of school, health organization and clinic management are the most difficult to get the cooperation from the persons relate to school and communities. There are a lot of problems in performing the school health nursing activity without any disposition of school health teachers, therefore, it is necessary to supplement school health teachers who had a professional training in order to make efficient the school health nursing management for children who are about to attend a school.

• 한국습지학회지
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• 제22권1호
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• pp.8-14
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• 2020

본 연구는 기후변화 민감종의 하나인 멸종위기야생동물II급, 맹꽁이(Kaloula borealis)의 생체량이 위도가 다른 세 지역(서울, 논산, 부산)에서 어떠한 차이를 보이는 지를 알아보기 위해 수행되었다. 맹꽁이 포획을 위해서 함정트랩(pitfall traps)과 유도트랩(inducement traps)을 이용하였으며, 각 서식지별 환경조건(온도, 강수량, 습도)을 파악하여 지역별로 비교하였다. 조사결과, 맹꽁이 수컷의 경우, 부산지역 개체의 크기가 41.6±0.39mm, 생체량이 11.3±0.17g으로 가장 크고 무거운 것으로 확인되었으며, 서울과 논산의 경우 크기가 각각 36.6±2.03mm, 36.6±1.76mm, 생체량은 각각 8.1±0.55g, 8.2±0.91g으로 통계적으로 큰 차이를 보이지 않았다. 맹꽁이 암컷의 경우, 부산 개체의 크기는 44.7±0.35mm, 생체량이 13.1±0.18g으로 긴 것으로 조사되었으나, 중량은 지역별 차이가 크지 않았다. 결과적으로 부산에 서식하는 맹꽁이의 암·수 모두 다른 지역의 개체들의 크기와 생체량이 더 큰 것으로 나타났다. 본 논문은 현재 기후상태의 기준이 되어 종복원에 대한 연구 수행 시 중요한 자료로 이용 될 수 있을 것으로 보이며, 장기적으로 조사가 진행된다면, 기후변화에 따른 양서류 무미목의 생체량 변화를 파악할 수 있는 기반이 될 수 있을 것으로 기대된다.

• Journal of Preventive Medicine and Public Health
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• 제2권1호
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• pp.5-22
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• 1969

The urban population of our country is rapidly increasing due to many factors of social structure, and sociologists are predicting that the increase rate of the urban population will be over 50% in 1980's. Above all, the population of the capital city of Seoul, is at present more than four millions. Such centring of people in cities, together with the improvement of the standards of living, caused rapid increase in the amount of fuel consumption, and this consumption of fuels became one of the primary sources of the air pollution in cities. Moreover, the heavy traffic, construction of many tall buildings, and the increasing number of new factories due to the industrial development-all these are contributing to make the matter of air pollution worse and worse in the Metropolitan, whose geographical location is quite unfavorable considered from the view point of air pollution. Most homes in Seoul use briquet as fuel, while oils are used in tall buildings. The CO, $SO_2$, and smoke that come from burning of these fuels are a great threat to the health of the urban population. With the purpose of examining the influence of air pollution upon the public health, written inquiries were made upon respiratory diseases, and the carboxyhemoglobin saturation in the blood was measured to determine whether the air pollution may affect the health of the urban population. Method of Health Examination (1) Investigation of Respiratory Diseases Patients' records were examined to figure out the monthly ambulance rate of respiratory patients to the total number of patients treated. On the other hand, by using the questionnaire form approved by the Medical Research Council's Committee on Research into Chronic Bronchitis, investigators interviewed the examinees and inquired into the respiratory symptoms. (2) Measuring of Carboxyhemoglobin Saturation From the ear lobe of the examinees, with the use of the melangeur for the white blood cell counting, blood was taken, and after diluting it ten times with 0.1% $Na{2}CO_{3}$, again diulting it 20 times with 0.5% $Na_{2}\;CO_{3}$, its absorbancy was measured. The following results are obtained from the investigation. (1) It was found out that 7.7% of the total patients under treatment were suffering from upper respiratory infection, acute or chronic bronchitis, bronchial asthma, pulmonary emphysema and bronchiectasis. Of them all, patients with upper respiratory infection numbered the greatest with 4.8% and patients with acute or chronic bronchitis the next with 2.1%, and their monthly ambulance rate was high from December to February during the winter, and from April to May and from September to October during the changeable seasons. (2) The daily ambulance rate of respiratory patients, it was revealed, had a close connection with the concentration of $SO_2$ and CO in the air. (3) It was found out that men were more subject to respiratory disease than women, and both men and women were more liable to the diseases with the advancing of age. (4) People living at Choong-ku with the heavy traffic and in the industrial zones of Yeungdungpo had high frequency of respiratory symptoms. (5) Considered from the view point of occupations, high frequency was found among those without job, with jobs unknown, merchants and intdustrial workers, whose social status was rather low and traffic policemen who were always exposed to the exhaust gas of cars. As for women, the frequency was detected in the order of those from high to low, housewives who were exposed to briquet gas, women with jobs unknown, women without jobs, whose social status was low. (6) Ex-smokers rather than smokers, of both sexes, had higher frequency. As for men, heavy smokers had high frequency, while in women light smokers had rather high frequency which was presumed to be due to their average old age. (7) Men's average of carboxyhemoglobin saturation was 9.48%, while women's was 11.3%, higher than men's. (p<0.05). Age meant no difference in the case of men, but as for women, the saturation was remarkably high between the ages from 20 to 60. (8) No regional difference was detected in the carboxyhemoglobin saturation. (9) The carboxyhemoglobin saturation was found, in the case of men, in the order of office workers, traffic policemen, students, the unemployed, merchants and industrial workers, drivers; and as for women, the order was housewives, office workers, merchants and industrial workers. (10) No significant correlation was found between the carboxyhemoglobin saturation and the concentration of CO detected in kitchens, or between the carhoxyhemoglobin saturation and the passing of time after exposure to briquet gas. No difference of carboxyhemoglobin saturation was detected between smokers and non-smokers, and the degrees of smoking; only, significant negative correlation was found between the passing of time after smoking and the carboxyhemoglobin saturation. It is ture that air pollution causes or aggravates the respiratory diseases, increases the carboxyhemoglobin saturation in the blood, but what seems to be more hazardous to the health is the air polluted by the briquet gas in the kitchens and on-dol rooms rather than the atmospheric air pollution.

• 한국동물위생학회지
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• 제14권2호
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• pp.87-103
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• 1991

The somatic cell counts SCC and bacteria counts were done by D milk plant, P milk plant, S milk plant and Inch'${\v{\times}}n$ Vet. Serv. Lab from 1987 to 1990 with Coulter counter, Fossomatic 90, Bactoscan, Rolling ball viscometer and Resazurin reduction test. The results were summarized as follows 1. In the distribution of SCC of the bulk herd milk, D milk plant from Nov. 1989 to Oct. 1990 remarks 80.2% on the range below 500, 000, 14.5% ranging from 1, 000, 000 to 1, 500, 000, 1.2% ranging from 1, 500, 000 to 2, 000, 000, 0.69% ranging from 2, 000, 000 to 3, 000, 000, 0.71% on the range over 3, 000, 000. P milk plant remarks 237, 000 in the first half year and 251, 000 in the second half year in 1990 year. S milk plant remarks annual average of 335, 000 in 1987, 273, 000 in 1988 and 262, 000 in 1989. The individual record of Inch'${\v{\times}}n$ Vet. Serv Lab. remarks 79.35% and 80.2% below 500, 000 8.30% and 7.40% from 500, 000 to 1, 000, 000, 2.37% and 3.2% from 1, 000, 000 to 1, 500, 000, 2.77% and 2.30% from 1, 500, 000 to 2, 000, 000, 1.67% and 2.00% from 2, 000, 000 to 3, 000, 000, 5.53% and 4.40% over 3, 000, 000 in 1989 and 1990, respectively. The grade distirbution of SCC is as follows: D milk plant shows 1st grade-80.20%, 2nd grade-l6.5% and 3rd grade-3.30%. And P milk plant shows all 1st grade. S milk plant shows 87.30%, 8.6% and 4.1% in 1987 and 91.90%, 6.1% and 2.0% in 1988, and 92.40%, 6.1% and l.5% in 1989 on the 1st, 2nd and 3rd grade respectively. 2. The distribution of bacteria P milk plant reached 15.123 in 1st half year and 21.515 in 2nd half year. Also, S milk plant reached 81.5%, 12.5%, 6.0% in 1987, and 86.20%, 9.70%, 4.1% in 1988, and 86.2%, 10.8%, 3.0% in 1989 respectively for 1st, 2nd and 3rd grade. 3. The regional SCC distribution in D milk plant shows 1, 540, 000 in three regions and 714, 000 in one region. And monthly SCC distribution shows 671, 000 in December and 1, 165, 000 in June. 4. As a result of the individual SCC test, 9 times for 16 cows in “I”farm(1986-1988), and 6 times for 13 cows in“D”farm(1987-1988) No.3, 5, 9, 14 cows in“I”farm showed the high SCC beyond 1, 000, 000 over 4-5times. 5. If the SCC over 300, 000 reach 40%, the national producing quality of milk can be reduced by 87, 600M /I annually and in the sum of money, it should be about 35.5 billion Won. 6. The difference between high group and low group for SCC in D milk plant reached over 1, 000, 000. In case that the difference reaches 1, 000, 000 in the farm bulk milk at a farm breeding 20 cows which produce 20kg milk per day, it was estimate that the annual difference of producing quantity and sum of money respectively should be reached 26, 280kg in milk and 10, 643, 400 Won in income.

• 대한핵의학회지
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• 제33권3호
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• pp.247-261
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• 1999

목적 : Tc-99m HMPAO 아세타졸아미드(이하, ACZ) 부하 뇌관류 SPECT(이하 중재적 SPECT)는 뇌혈관 질환에서 조기진단, 수술 적응증 선별이나 방법 결정, 그리고 수술 효과 판정과 경과 관찰시 매우 유용하게 사용되고 있다. 중재적 SPECT의 정화한 해석과 진단율을 높이기 위해서는 정상인의 CVR 자료가 필요하지만 국내엔 이런 자료가 없다. 본 연구에서는 연령에 따라 뇌혈류분포와 혈류예비능이 차이를 보이는지 알아보고자 하였다. 대상 및 방법: 정상 지원자 34명을 대상으로 하였고, 남자 20명, 여자 14명이었으며, 평균연령은 $40.3{\pm}24.9$세, 범위는 4세에서 82세였다. 이들은 신경학적 검사상 특이 소견이 없었으며, 뇌혈관질환, 당뇨, 고혈압, 허혈성 심질환, 그리고 두부외상의 병력은 없었다. 중재적 SPECT는 Tc-99m HMPAO와 이중 헤드 회전형 감마카메라를 이용하여 휴식 및 ACZ부하 SPECT를 연속적으로 시행하여 감산영상을 얻는 방법을 사용하였다. Tc-99m HMPAO는 휴식 및 부하 모두 925 MBq을 주사하였다. ACZ(성인: 1 g, 소아: $250{\sim}500 mg$) 주사 후 23분째에 두 번째 Tc-99m HMPAO를 주사하고 10분 후 부하영상을 얻었다. 동일한 관심영역을 전두엽, 두정엽, 측두엽, 후두엽, 기저핵, 시상, 소뇌반구에 설정하여 평균 방사능계수를 얻었다. 정량적 지표로 R/L, R/Cbll와 R/WB를 사용하였다. 감산영상에서 구한 평균방사능계수를 상응한 휴식기 계수를 기준으로하여 백분율을 구하여 CVR 평가지표로 사용하였다. 모든 통계적 검정에서 통계적 유의성은 P값이 0.05 미만인 경우만 차이가 있다고 인정하였다. 결과: 한국 정상인에서 뇌혈류 분포는 전 연령에서 R/L의 대뇌반구의 평균 1.004에서 1.018로 좌우 대뇌반구간의 차이가 5%미만이었다. 각 연령군 모두에서 소뇌의 측정치가 가장 높았고, 기저핵과 시상은 가장 낮은 혈류분포를 보였다. 연령이 증가할수록 전두엽과 측두엽은 유의하게 감소하였고 후두엽과 시상부는 유의하게 증가하였다. 모든 연령에서 남녀간에 혈류분포의 차이는 없었다. CVR은 $29.9{\pm}12.9%$이었고, 소아에서는 CVR이 연령에 따라 유의하게 증가하여 10대 후반에 가장 높았다. $20{\sim}49$세 사이에는 서서히 감소하는 경향을 보였고, 50세 이상의 연령군에서 양측 전두엽, 좌측 두정엽, 그리고 우측 기저핵에서 나이가 들어감에 따라 의의있게 감소하였다. 평균 CVR이 여자에서 남자보다 높은 경향을 보였으나 통계학적으로 유의한 차이는 없었다. 결론: ACZ와 Tc-99m HMPAO을 이용한 감산법으로 CVR를 정량적으로 평가할 수 있었고, 한국 정상인에서 뇌혈류 분포와 CVR이 연령에 따라 변한다는 사실을 알 수 있었다.

• 대한핵의학회지
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• 제23권2호
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• pp.175-181
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• 1989

Visual assessment of regional wall motion abnormality (RWMA) by gated blood pol scan (GBPS) serves as an useful parameter in the diagnosis, functional evaluation, and follow up in various clinical settings, but are still subject to some inherent limitations. On important problem may be the interobserver as well as intraobsever variation that may well be present due to the subjective nature of the interpretations. This study was carried out to determine the reliability and reproducibility of visual assessments made in GBPSs, and to observe the degree to which the results would be influenced by observer variation. Fifty two patients with coronary heart disease had resting GBPS and contrast ventriculography within 4 days appall. Contrast ventriculography-showed normal wall motion in 6 patients and the remaining 46 had RWMA in one or more segments. The anterior and left anterolateral views of all 52 GBPSs were analyzed by three independent observers, who selected from 5 scales, their level of confidence that there was RWMA in that segment. Reciever operating characteristic (ROC) curves for each analysis was plotted and the area under the curve $(\theta)$ was used as a parameter representing each observer's performance in his interpretations. The findings of contrast ventriculographies were used as the standard for RWMA. The apical and inferoapical segments showed the best correlation with contrast ventriculography ($\theta=0.90-0.94$, 0.81-0.94, respectively), and the inferior wall showed the poorest correlation $(\theta=0.70-0.74)$. The interpretations of the inferior, septal, apical, and posteroinferior, segments showed no difference between the observers, but there was significantly better performance in assessment by observer A compared to that by B or C for the anterolateral segments ($\theta=0.87$, 0.78, 0.76, respectively. p<0.01 for A vs B, p<0.05 for A vs C), as well as when all segments were considered altogether ($\theta=0.88$, 0.83, 0.82, respectively. both p<0.05). This was also true for the infero-apical segment between A and C ($\theta=0.09$, 0.81, p<0.05). The intraobserver variation, however, did not appear significant, with only the inferior segment for observer B showing any significant difference when observer A and B repeated the analysis 10 days latter. There was no difference in assessing dyskinesia, with all observers showing a high performance ($\theta=0.98$, 0.87, 0.97, respectively). The visual assessment of left ventricular ejection fraction by all three observers correlated well with the calculated value from a semiautomated method (Spearman's r = 0.91, 0.83, 0.83. p<0.01, p<0.05, p < 0.05). The assessment of LV and RV size also correlated well between the three observers (Kendall's w = 0.80, 0.51, p<0.01 for both left and right ventricles). The above findings suggest that RWMA visually assessed by GBPS correlates well with that done by contrast ventriculography. And although the observer's experience or skill may influence the results in certain segments, visual analysis of GBPS may serve as a reliable and reproducible means for evaluating ventricular function.

• Clinical and Experimental Pediatrics
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• 제53권3호
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• pp.314-322
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• 2010

목 적 : 경남권역 응급의료센터인 마산삼성병원을 내원한 소아청소년 응급환자들을 후향적 방법으로 내원 양상을 분석하여 향후에 지역 응급 진료의 질 향상에 기여하고자 본 연구를 시행하였다. 방 법 : 2007년 1월 1일부터 2008년 12월 31일까지 2년 동안 마산삼성병원 응급센터로 내원하였던 19세 미만 소아청소년 환자 14,065명 의 의무 기록지를 통해 연구하였다. 결 과 : 남녀비는 1.5:1로 남자가 더 많았고, 연령은3세 미만이 49.6%였다. 내원 환자는 5월, 일요일, 하루 중에는 20시에서 21시 사이가 가장 많았다. 기후와의 관련에서 하루 내원 환자 수는 황사가 있을 때 3배, 맑은 날 또는 10 mm 미만의 비가 내린 경우는 10 mm 이상 비가 내렸을 때보다 4배 더 많았다. 주된 진료담당과는 전체의 62.0%가 소아과였다. ICD-10 질병 분류에서 손상 중독 및 외인에 의한 경우 22.4%, 단일 증상 및 질환으로는 발열이 13.1%로 가장 많았다. 최종 진료 처리 형태로는 퇴원이 73.8%, 입원은 25.7%였다. 15세 이상 19세 미만의 청소년인 경우 전체 연령과 다른 점은 응급의학에서 50.0%를 담당하였고, 손상 중독 및 외인에 의한 경우 36.9%, 단일 증상 질환으로는 복통이 10.9%로 가장 많았다. 또 최종 입원한 경우는 30.6%로 전체 연령보다는 더 많았고 내원 환자수가 일교차가 클수록 비례하여 더 많았다. 결 론 : 응급센터를 내원한 소아 환자 수는 남자, 3세 미만, 5월, 일요일, 20-21시 사이, 황사가 없는 맑은 날, 손상 중독 및 외인에 의한 경우 및 발열인 경우가 가장 많았다. 청소년이 소아환자와 다른 점은 일교차가 클 수록, 복통으로 내원하는 경우가 더 많았다.

• Journal of Chest Surgery
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• 제38권2호
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• pp.101-109
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• 2005

배경: 심정지와 같은 위급상황에서 관상동맥의 혈류를 유지하는 것은 심장근육의 보존과 회복 및 환자의 생명을 보존하는 데 중요하다. 최근 들어 Extra-Corporeal Life Support System (ECLS)의 기계식 순환장치의 사용으로 심정지 환자의 생명을 보존하고자 하는 노력이 시도되고 있다 본 연구는 체외순환 모델에서 박동성 혈류와 비박동성 혈류가 관상동맥의 혈류량 및 심근에 미치는 영향에 대해 알아보고자 하였다. 대상 및 방법: 실험은 $25\~35Kg$의 돼지 14마리를 각각 7마리씩 두 군으로 나누어 진행하였다. 제 1군은 비박동성 혈류 펌프인 원심펌프를 사용하였고 제2군은 이중 박동형 펌프를 사용하였다. 체외순환은 우심방에서 상행대동맥으로 심폐바이패스를 하고, 9V의 전기 충격으로 심실세동을 만들었다. 체외순환은 2시간 동안 유지하였으며, 펌프량은 두 군 모두 2 L/min로 유지하였다. 초음파를 이용한 관상동맥 혈류 측정장치를 이용하여 좌전하행지의 관상동맥 관류량을 펌프 시작 전(기초치)과 시작 후 20분마다 측정하였다. 또한 관상 정맥동의 혈액을 펌프 시작 전(기초치)과 시작 후 1시간, 2시간에 채취하여 두 군간의 심근효소의 차이와 대사물질의 차이를 비교하였다. 각 관찰지표의 군간 비교는 STATISTICA 통계프로그램(Version 6.0)의 Mann-Whitney U test를 이용하였고 통계적 유의수준은 p값이 0.05 이하인 경우로 하였다. 결과: 관상동맥의 저항지수는 제 2군에서 낮게 나타났으며, 펌프 구동 후 40분, 80분, 100분, 120분에서 통계적으로 의미 있게 나타났다 (p<0.05). 관상동맥의 평균 혈류 속도는 제 2군에서 펌프 구동 후 20분부터 의미 있게 높게 유지되었다(p<0.05). 관상동맥의 혈류량도 제2군에서 높게 유지되었으며, 펌프 구동 후 40분, 60분, 100분, 120분에서 통계적으로 의미 있는 차이를 보였다(p<0.05). 그러나, 관상정맥동의 혈액학적 검사에서는 두 군간에 차이가 없었다. 결론: 박동성 혈류는 비박동성 혈류보다 좌전하행지 관상동맥의 저항지수를 낮추고, 관상동맥의 관류속도를 빠르게 하여, 관상동맥으로의 혈류량을 높게 유지하였다.