• Title/Summary/Keyword: region contrast

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Effects of Mutations in the Regulatory Region on Transcriptional Regulation of glpD Gene

  • Jeong, Hee-Tae;Choi, Yong-Lark;Chung, Soo-Yeol;Chung, Chung-Han
    • Journal of Microbiology and Biotechnology
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    • v.5 no.5
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    • pp.245-249
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    • 1995
  • Expression of the adjacent but divergently transcribed glpD and glpE gene is positively regulated by cAMP-CRP. In this study, we constructed several mutants in which a CRP-binding site is placed at different distances upstream of the glpD promoter. The effect of the spacer length on transcription activation by cAMP-CRP was tested in vivo by $\beta$-galactosidase. The cAMP-CRP complex activated transcription from glpD when bound at a number of positions, all of which lay on the same face of the DNA helix, although the degree of activation varied with the length of the spacer. By contrast, the insertion of spacer length with non-integral turns of the DNA helix extremely inhibited the activation of transcription. The observed transcription activation by cAMP of the glpD promoter was influenced by the distance between the CRP binding site and the transcription start point.

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FAR-INFRARED [C II] EMISSION FROM THE CENTRAL REGIONS OF SPIRAL GALAXIES

  • MOCHIZUKI KENJI
    • Journal of The Korean Astronomical Society
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    • v.37 no.4
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    • pp.193-197
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    • 2004
  • Anomalies in the far-infrared [C II] 158 ${\mu}m$ line emission observed in the central one-kiloparsec regions of spiral galaxies are reviewed. Low far-infrared intensity ratios of the [C II] line to the continuum were observed in the center of the Milky Way, because the heating ratio of the gas to the dust is reduced by the soft interstellar radiation field due to late-type stars in the Galactic bulge. In contrast, such low line-to-continuum ratios were not obtained in the center of the nearby spiral M31, in spite of its bright bulge. A comparison with numerical simulations showed that a typical column density of the neutral interstellar medium between illuminating sources at $hv {\~} 1 eV $ is $N_H {\le}10^{21}\;cm^{-2}$ in the region; the medium is translucent for photons sufficiently energetic to heat the grains but not sufficiently energetic to heat the gas. This interpretation is consistent with the combination of the extremely high [C Il]/CO J = 1-0 line intensity ratios and the low recent star-forming activity in the region; the neutral interstellar medium is not sufficiently opaque to protect the species even against the moderately intense incident UV radiation. The above results were unexpected from classical views of the [C II] emission, which was generally considered to trace intense interstellar UV radiation enhanced by active star formation.

A new coupling method of Element-Free Galerkin Method and Boundary Element Method for infinite domain problems in elasticity (무한탄성영역 해석을 위한 EFG와 BEM의 새로운 결함기법 개발)

  • 이상호;김명원
    • Proceedings of the Computational Structural Engineering Institute Conference
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    • 2002.10a
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    • pp.575-582
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    • 2002
  • A new coupling method of Element-Free Galerkin Method(EFGM) and Boundary Element Method(BEM) using the domain decomposition method is presented in this paper. This proposed methodology is that the problem domain is decomposed into sub-domains being modeled by the EFGM and BEM respectively and the respective EFGM and BEM domains share a partially overlapped region over an entire domain. Then, the each sub-domain is separately computed and the variables on common region are iteratively updated until converging. It is an important note that in the developed coupling method, there is no need to combine the coefficient matrices of EFGM and BEM sub-domains, in contrast with the other conventional coupling methods. In the first part of this paper, a theory of EFGM and BEM is summarized, and then a brief introduction of domain decomposition method is described. Then, a new coupling method is presented. Also, patch test and Some numerical examples are studied to verify stability, accuracy and efficiency of the proposed method, in which numerical performance of the method is compared with that of conventional method such as EFGM-BEM variational coupling method, EFGM and BEM.

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Design of SPS in the Korean Power System Against Faults on 765 KV Lines

  • Park Jong-Young;Park Jong-Keun;Jang Byung-Tae
    • KIEE International Transactions on Power Engineering
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    • v.5A no.2
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    • pp.132-137
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    • 2005
  • In Korea, the protection systems against the instability of the nation's power system are insufficient in contrast with many other countries. In addition, there have just been studies carried out on detecting power system instability, while only a few studies pertaining to protection plans against instability exist. This paper focuses on systems to protect against the instability phenomena in the Korean power system. In this paper, we survey possible contingencies in the Korean power system and suggest outline and specs of the SPS (System Protection Scheme) against faults on the 765 kV line, based on simulations. It is concluded that event-based SPS for transient stability is appropriate for the Korean power system. In the simulations, the most severe contingency on the Korean power system is the fault on 765 kV transmission lines. If one of these lines is tripped by a fault, synchronism may be lost on the power plants near this line because of heavy power flow carried by them. In addition, undervoltage in the Metropolitan region is a serious problem in this case since this region receives about half its total power flow through these lines. In order to prevent a synchronism loss, some power plants have to be rejected according to the situations in the simulations.

TFT-LCD Defect Enhancement Using Frequency Sensitivity of HVS (인간 시각시스템의 주파수 감도를 이용한 TFT-LCD 결함 강조)

  • Oh, Jong-Hwan;Park, Kil-Houm
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • v.44 no.5
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    • pp.20-27
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    • 2007
  • Generally, the TFT-LCD image signal have nonuniform brightness and are composed of largely varying background signal, noise signal and abruptly changing Mura signal within Mura region. In this paper, Mura region enhancing algorithms using the proposed modified-MTF, which describes how human-visual-system's sensitivity varies in frequency domain, is proposed. The validity of the proposed algorithm was demonstrated ideal 1-dimensional signal and also then it was also tested TFT-LCD image. By the experimental results, the proposed algorithm is very effective in TFT-LCD image Mura enhancement.

A Numerical Study on the Formation Mechanism of a Mesoscale Low during East-Asia Winter Monsoon

  • Koo, Hyun-Suk;Kim, Hae-Dong;Kang, Sung-Dae;Shin, Dong-Wook
    • Journal of the Korean earth science society
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    • v.28 no.5
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    • pp.613-619
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    • 2007
  • Mesoscale low is often observed over the downstream region of the East Sea (or, northwest coast off the Japan Islands) during East-Asia winter monsoon. The low system causes a heavy snowfall at the region. A series of numerical experiments were conducted with the aid of a regional model (MM5 ver. 3.5) to examine the formation mechanism of the mesoscale low. The following results were obtained: 1) A well-developed mesoscale low was simulated by the regional model under real topography, NCEP reanalysis, and OISST; 2) The mesoscale low was simulated under a zonally averaged SST without topography. This implies that the meridional gradient of SST is the main factor in the formation of a mesoscale low; 3) A thermal contrast ($>10^{\circ}C$) of land-sea and topography-induced disturbance served as the second important factor for the formation; 4) Paektu Mountain caused the surface wind to decelerate downstream, which created a more favorable environment for thermodynamic modification than that was found in a flat topography; and 5) The types of cumulus parameterizations did not affect the development of the mesoscale low.

Chordoid Glioma Originating in the Intrasellar and Suprasellar Regions: Case Report

  • Hwang, Jisun;Lee, Aleum;Chang, Kee-Hyun;Moon, Ah Rim;Hwang, Sun-Chul;Hong, Hyun Sook
    • Investigative Magnetic Resonance Imaging
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    • v.19 no.2
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    • pp.117-121
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    • 2015
  • Chordoid glioma is a rare, low-grade brain neoplasm typically located in the third ventricle. Herein, we report an unusual case of histologically confirmed chordoid glioma located in the pituitary fossa and suprasellar region, not attached to the third ventricle. A 57-year-old woman presented with a 2-month history of headache and visual disturbance. Magnetic resonance imaging revealed an ovoid mass in the pituitary fossa and suprasellar region, compressing the optic chiasm without involvement of the third ventricle. The tumor showed low signal intensity on T1-weighted images and iso- to high signal intensity on T2-weighted images, with strong and homogenous contrast enhancement. Subtotal resection was performed via the transcranial approach, and the patient subsequently received adjuvant gamma knife radiosurgery. However, the residual mass showed disease progression 5 months after the initial surgery.

Comparison of Binding Stoichiometry of [Ru(1,10-phenanthroline)2dipyrido [3,2-a:2',3'-c]phenazine]2+ and its Bis-derivative to DNA

  • Jang, Yoon-Jung;Lee, Hyun-Mee;Lee, Il-Bong
    • Bulletin of the Korean Chemical Society
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    • v.31 no.12
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    • pp.3658-3662
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    • 2010
  • A new bis-Ru(II) complex, in which two [Ru(1,10-phenanthroline)$_2$dipyrido[3,2-a:2',3'-c]phenazine]$^{2+}$ were tethered by a 1,3-bis(4-pyridyl)propane linker, was synthesized and its binding mode and stoichiometry to DNA was investigated by optical spectroscopy including linear dichroism (LD) and fluorescence intensity measurement. The magnitude of the negatively reduced LD signal of the bis-Ru(II) complex in the dipyrido[3,2-a:2',3'-c]phenazine (DPPZ) ligand absorption region appeared to be similar compared to that in the DNA absorption region, which is considered to be a diagnostic for DPPZ ligand intercalation. The binding stoichiometry measured from its LD magnitude and enhanced fluorescence intensity corresponds to one ligand per three DNA bases, effectively violating the nearest neighbouring site exclusion model for classical DNA intercalation. This observation is in contrast with monomer analogue [Ru(1,10-phenanthroline)$_2$dipyrido[3,2-a:2',3'-c]phenazine]$^{2+}$, which is saturated at the DPPZ ligand to DNA base ratio of 0.25, or one DPPZ ligand per four nucleobases.

A Photometric Study of Star Clusters in Nearby Barred Spiral Galaxies

  • Jang, In-Sung;Lee, Myung-Gyoon
    • The Bulletin of The Korean Astronomical Society
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    • v.36 no.1
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    • pp.63.2-63.2
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    • 2011
  • We present a photometric study of star clusters in three nearby barred spiral galaxies NGC 1300, NGC 1672 and NGC 6217. We use the Hubble Heritage CCD images taken with Advanced Camera for Surveys (ACS) of Hubble Space Telescope (HST) in several filters. We have selected hundreds of star clusters with V $\leq$ 24 mag in each galaxy, based on the morphological parameters and visual inspection. Most of the blue star clusters with B-V $\leq$ 0.5 are strongly concentrated in spiral arms. A significant fraction of these star clusters are distributed in ansae (the joint between spiral arms and bar structure). Some of the blue star clusters are also found in the nuclear starburst region, especially in NGC 1672. A small number of star clusters are found in the bar region. In contrast, the red star clusters with B-V < 0.5 are relatively uniformly located over the entire field of galaxy, and show some central concentration around the bulge. We discuss the physical properties of these star clusters with the expected results from simulations.

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Optimized Design of Bi-Directional Dual Active Bridge Converter for Low-Voltage Battery Charger

  • Jeong, Dong-Keun;Ryu, Myung-Hyo;Kim, Heung-Geun;Kim, Hee-Je
    • Journal of Power Electronics
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    • v.14 no.3
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    • pp.468-477
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    • 2014
  • This study proposes an optimized design of a dual active bridge converter for a low-voltage charger in a military uninterrupted power supply (UPS) system. The dual active bridge converter is among various bi-directional DC/DC converters that possess a high-efficiency isolated bi-directional converter. In the general design, the zero-voltage switching(ZVS) region is reduced when the battery voltage is high. By contrast, efficiency is low because of high conduction losses when the battery voltage is low. Variable switching frequency is applied to increase the ZVS region and the power conversion efficiency, depending on battery voltage changes. At the same duty, the same power is obtained regardless of the battery voltage using the variable switching frequency. The proposed method is applied to a 5 kW prototype dual active bridge converter, and the experimental results are analyzed and verified.