• Title/Summary/Keyword: reference range

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Hair Diameter Variation in Different Vertical Regions of the Occipital Safe Donor Area

  • Yun, Seon Sik;Park, Jae Hyun;Na, Young Cheon
    • Archives of Plastic Surgery
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    • v.44 no.4
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    • pp.332-336
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    • 2017
  • Background Little is known concerning hair diameter variation within the safe donor area for hair transplantation surgery. Thicker or thinner hair may be needed, depending on the recipient area, hairline design, and the purpose of surgery. Methods Twenty-seven patients (7 men and 20 women; mean age, 28 years; range, 20-47 years) were included in this study. The midoccipital point was used as the reference point on the horizontal plane at the upper border of the helical rim. The target area width was 15 cm (7.5 cm to the right and left of the reference point) and the height was 8 cm (2 cm above and 6 cm below the reference point). The study area was divided horizontally into 3 5-cm sections (A, B, C) and vertically into 4 2-cm sections (1-4), creating a total of 12 zones. Ten anagen hairs were randomly obtained from each zone and their diameters were measured. Results Hair diameter in the 4 vertical sections varied significantly, gradually decreasing from sections 1 (superior) to 4 (inferior) in all 3 horizontal sections (A, B, and C). Conclusions Our results suggest that sections 1 and 2 of the occipital safe donor area would be useful for obtaining thicker hair, such as in procedures to treat male- and female-pattern hair loss, whereas hair from zones 3 and 4 could be useful for transplantation surgery requiring thinner hair, such as eyebrows, eyelashes, and female hairline correction. Our results may be clinically valuable for planning hair transplant surgery and choosing the optimal donor region.

A Design of Collision Avoidance System of an Underwater Vehicle (수중운동체의 충돌회피시스템에 대한 연구)

  • Nam-Sun Son;Key-Pyo Rhee;Sang-Mu Lee;Dong-Jin Yeo
    • Journal of the Society of Naval Architects of Korea
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    • v.38 no.4
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    • pp.23-29
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    • 2001
  • An Obstacle Avoidance System(OAS) of Underwater Vehicle(UV) in diving and steering plane is investigated. The concept of Imaginary Reference Line(IRL), which acts as the seabed in the diving plane, is introduced to apply the diving plane avoidance algorithm to the steering plane algorithm. Furthermore, the distance to the obstacle and the slope information of the obstacle are used for more efficient and safer avoidance. As for the control algorithm, the sliding mode controller is adopted to consider the nonlinearity of the equations of motion and to get the robustness of the designed system. To verify the obstacle avoidance ability of the designed system, numerical simulations are carried out on the cases of some presumed three-dimensional obstacles. The effects of the sonar and the clearance factor used in avoidance algorithm are also investigated. Through these, it is found that the designed avoidance system can successfully cope with various obstacles and the detection range of sonar is proven to bea significant parameter to the performance of the avoidance.

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Design of Navigation Environment Generation Module of M&S Software for Integrated Navigation System Performance Evaluation

  • Kim, Heyone;Lee, Junhak;Oh, Sang Heon;So, Hyoungmin;Hwang, Dong-Hwan
    • Journal of Positioning, Navigation, and Timing
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    • v.7 no.2
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    • pp.73-90
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    • 2018
  • Various navigation systems are integrated with the Global Navigation Satellite System (GNSS) to improve navigation performance so that continuous navigation information can be obtained even when navigation performance is degraded or navigation is not available due to the outage of GNSS. Time and cost can be reduced by evaluating performance of the integrated navigation system through Modeling and Simulation (M&S) software prior to the deployment of the integrated navigation system. The measurements of the navigation system should be generated to evaluate performance through of the navigation system M&S software. This paper proposes a method of designing a navigation environment generation module in M&S software of the integrated navigation system. To show applicability of the proposed method to M&S software design of the integrated navigation system, functions are verified through MATLAB. And then visual C++ based M&S software for the integrated navigation system is implemented to check the operation of the navigation environment generation module. The reference trajectory is generated and true measurements of Global Positioning System (GPS), Korea Positioning System (KPS), and enhanced Long range navigation (eLoran) are generated from the reference trajectory. The navigation results obtained from the true measurements are compared with the reference trajectories. The results show that the measurements generated using the design generation module by the proposed method are valid and the navigation environment generation module can be applied to M&S software of the integrated navigation system.

Power Smoothening Control of Wind Farms Based on Inertial Effect of Wind Turbine Systems

  • Nguyen, Thanh Hai;Lee, Dong-Choon;Kang, Jong-Ho
    • Journal of Electrical Engineering and Technology
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    • v.9 no.3
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    • pp.1096-1103
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    • 2014
  • This paper proposes a novel strategy for attenuating the output power fluctuation of the wind farm (WF) in a range of tens of seconds delivered to the grid, where the kinetic energy caused by the large inertia of the wind turbine systems is utilized. A control scheme of the two-level structure is applied to control the wind farm, which consists of a supervisory control of the wind farm and individual wind turbine controls. The supervisory control generates the output power reference of the wind farm, which is filtered out from the available power extracted from the wind by a low-pass filter (LPF). A lead-lag compensator is used for compensating for the phase delay of the output power reference compared with the available power. By this control strategy, when the reference power is lower than the maximum available power, some of individual wind turbines are operated in the storing mode of the kinetic energy by increasing the turbine speeds. Then, these individual wind turbines release the kinetic power by reducing the turbine speed, when the power command is higher than the available power. In addition, the pitch angle control systems of the wind turbines are also employed to limit the turbine speed not higher than the limitation value during the storing mode of kinetic energy. For coordinating the de-rated operation of the WT and the storing or releasing modes of the kinetic energy, the output power fluctuations are reduced by about 20%. The PSCAD/EMTDC simulations have been carried out for a 10-MW wind farm equipped with the permanent-magnet synchronous generator (PMSG) to verify the validity of the proposed method.

Survey of ERETIC2 NMR for quantification

  • Hong, Ran Seon;Hwang, Kyung Hwa;Kim, Suncheun;Cho, Hwang Eui;Lee, Hun Joo;Hong, Jin Tae;Moon, Dong Cheul
    • Journal of the Korean Magnetic Resonance Society
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    • v.17 no.2
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    • pp.98-104
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    • 2013
  • The ERETIC (Electronic REference To access In vivo Concentrations)2 method is a new qNMR experimental technique to measure analytes based on the signal of the reference compound without additional hardware equipment. In this study, ERETIC2 method was validated, and we sought to identify whether it would be possible to apply this method to a specific compound analysis of metabolites in plant. The $90^{\circ}$ pulse value (P1) and spin-lattice relaxation time ($T_1$) of each compound were measured for ERETIC2. The $9^1H$ of 3-(trimethylsilyl) propionic-2,2,3,3-$d_4$ acid (TSP) was used as a reference peak for ERETIC 2, and then, a suitable solvent and pulse sequence for each compound were selected. Under the NOESY-presat sequence, the relative accuracy error for quantitative analyses of primary metabolites was within the range of 5%, with the exception of glucose, which showed ${\geq}$ 55% error due to saturation. It showed excellent results for the quantification of glucose by using a $30^{\circ}$ pulse sequence, which did not suppress the water peak. In addition, the quantitative accuracy for secondary metabolites was extremely accurate, with an error ${\leq}$5% when considering the purity of the standard sample. The ERETIC2 method showed outstanding linearity, precision, and accuracy.

A new validated analytical method for the quality control of red ginseng products

  • Kim, Il-Woung;Cha, Kyu-Min;Wee, Jae Joon;Ye, Michael B.;Kim, Si-Kwan
    • Journal of Ginseng Research
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    • v.37 no.4
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    • pp.475-482
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    • 2013
  • The main active components of Panax ginseng are ginsenosides. Ginsenoside Rb1 and Rg1 are accepted as marker substances for quality control worldwide. The analytical methods currently used to detect these two compounds unfairly penalize steamed and dried (red) P. ginseng preparations, because it has a lower content of those ginsenosides than white ginseng. To manufacture red ginseng products from fresh ginseng, the ginseng roots are exposed to high temperatures for many hours. This heating process converts the naturally occurring ginsenoside Rb1 and Rg1 into artifact ginsenosides such as ginsenoside Rg3, Rg5, Rh1, and Rh2, among others. This study highlights the absurdity of the current analytical practice by investigating the time-dependent changes in the crude saponin and the major natural and artifact ginsenosides contents during simmering. The results lead us to recommend (20S)- and (20R)-ginsenoside Rg3 as new reference materials to complement the current P. ginseng preparation reference materials ginsenoside Rb1 and Rg1. An attempt has also been made to establish validated qualitative and quantitative analytical procedures for these four compounds that meet International Conference of Harmonization (ICH) guidelines for specificity, linearity, range, accuracy, precision, detection limit, quantitation limit, robustness and system suitability. Based on these results, we suggest a validated analytical procedure which conforms to ICH guidelines and equally values the contents of ginsenosides in white and red ginseng preparations.

Lead isotope measurement of geological reference materials using thermal ionization mass spectrometry (열이온화질량분석기를 이용한 암석표준시료에 대한 납 동위원소 분석)

  • Lee, Hyo Min;Jo, Hui Je;Kim, Taehoon
    • Analytical Science and Technology
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    • v.33 no.6
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    • pp.245-251
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    • 2020
  • Lead (Pb) has been shown to be a useful tracer of contamination sources and geochemical processes such as age dating and crustal evolution. These studies require a chromatographic technique for Pb separation from geological samples. This paper presents a comparison study on the effect of eluent concentration between 6M HCl and 8M HCl on the separation of Pb from Pb resin. The results showed that the separation of Pb using 6M HCl as the eluent was not effective compared to the separation using 8M HCl. To verify this method, we measured the Pb isotopic compositions of the Pb isotopic standard (NIST NBS981) and geological reference materials (BCR-2, GSP-2, and JG-1a) using a thermal ionization mass spectrometer (TIMS). The results correspond well with the reported values within the error range, implying that this method can be useful.

Study on the Tiered Applicability of Health-Based Reference Value in Chemical Risk Assessment (화학물질 위험성 평가 시 건강영향 기준값의 단계적 적용에 관한 고찰)

  • Hye Jin, Lee;Naroo, Lee
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.32 no.4
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    • pp.350-358
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    • 2022
  • Objectives: For chemical risk assessment in workplaces, it is necessary to determine a reference value through hazard assessment. In general, OEL (Occupational Exposure Limit) is used for this value. However, since chemicals with OEL were not enough, the concept of DNEL (Derived No Effect Level) was introduced in chemical safety assessment. In this study, the possibility and approach of applying DNEL for chemical risk assessment in domestic workplaces were investigated. Methods: The characteristics of OEL and DNEL were investigated. In addition, ACGIH TLV and GESTIS DNEL were compared and the corresponding scopes were analyzed among the chemical substances notified in South Korea. Results: OEL and DNEL are similar concepts reflecting reference values that should not be exposed based on health effects. While their evaluation and derivation are determined based on similar information and procedures, they may vary depending on the responsible actor, data availability, principles of judgment, and more. As a result of the comparative analysis of ACGIH TLV and GESTIS DNEL, it was confirmed that there is some correlation between TWA and DNEL. The conservatism of DNEL was around 50%. Additionally, it was found that the available range of DNEL among chemicals in South Korea is considerable. Conclusions: This study showed that DNEL can be applied when assessing the risk of chemical substances in domestic workplaces considering several regards. However, since this is not the same level as OEL, we have proposed a proper approach to carry out risk assessment step by step.

A 0.16㎟ 12b 30MS/s 0.18um CMOS SAR ADC Based on Low-Power Composite Switching (저전력 복합 스위칭 기반의 0.16㎟ 12b 30MS/s 0.18um CMOS SAR ADC)

  • Shin, Hee-Wook;Jeong, Jong-Min;An, Tai-Ji;Park, Jun-Sang;Lee, Seung-Hoon
    • Journal of the Institute of Electronics and Information Engineers
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    • v.53 no.7
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    • pp.27-38
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    • 2016
  • This work proposes a 12b 30MS/s 0.18um CMOS SAR ADC based on low-power composite switching with an active die area of $0.16mm^2$. The proposed composite switching employs the conventional $V_{CM}$-based switching and monotonic switching sequences while minimizing the switching power consumption of a DAC and the dynamic offset to constrain a linearity of the SAR ADC. Two equally-divided capacitors topology and the reference scaling are employed to implement the $V_{CM}$-based switching effectively and match an input signal range with a reference voltage range in the proposed C-R hybrid DAC. The techniques also simplify the overall circuits and reduce the total number of unit capacitors up to 64 in the fully differential version of the prototype 12b ADC. Meanwhile, the SAR logic block of the proposed SAR ADC employs a simple latch-type register rather than a D flip-flop-based register not only to improve the speed and stability of the SAR operation but also to reduce the area and power consumption by driving reference switches in the DAC directly without any decoder. The measured DNL and INL of the prototype ADC in a 0.18um CMOS are within 0.85LSB and 2.53LSB, respectively. The ADC shows a maximum SNDR of a 59.33dB and a maximum SFDR of 69.83dB at 30MS/s. The ADC consumes 2.25mW at a 1.8V supply voltage.

A Temperature- and Supply-Insensitive 1Gb/s CMOS Open-Drain Output Driver for High-Bandwidth DRAMs (High-Bandwidth DRAM용 온도 및 전원 전압에 둔감한 1Gb/s CMOS Open-Drain 출력 구동 회로)

  • Kim, Young-Hee;Sohn, Young-Soo;Park, Hong-Jung;Wee, Jae-Kyung;Choi, Jin-Hyeok
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.38 no.8
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    • pp.54-61
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    • 2001
  • A fully on-chip open-drain CMOS output driver was designed for high bandwidth DRAMs, such that its output voltage swing was insensitive to the variations of temperature and supply voltage. An auto refresh signal was used to update the contents of the current control register, which determined the transistors to be turned-on among the six binary-weighted transistors of an output driver. Because the auto refresh signal is available in DRAM chips, the output driver of this work does not require any external signals to update the current control register. During the time interval while the update is in progress, a negative feedback loop is formed to maintain the low level output voltage ($V_OL$) to be equal to the reference voltage ($V_{OL.ref}$) which is generated by a low-voltage bandgap reference circuit. Test results showed the successful operation at the data rate up to 1Gb/s. The worst-case variations of $V_{OL.ref}$ and $V_OL$ of the proposed output driver were measured to be 2.5% and 7.5% respectively within a temperature range of $20^{\circ}C$ to $90^{\circ}C$ and a supply voltage range of 2.25V to 2.75V, while the worst-case variation of $V_OL$ of the conventional output driver was measured to be 24% at the same temperature and supply voltage ranges.

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