• 한국동물생명공학회지
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• 제34권4호
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• pp.280-291
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• 2019

Potential utility of 14 candidate housekeeping genes as normalization reference for RT-qPCR analysis with developmental samples (fertilized eggs to late veliger larvae) in Pacific abalone Haliotis discus hannai was evaluated using four different statistical algorithms (geNorm, NormFinder, BestKeeper and comparative ΔCT method). Different algorithms identified different genes as the best candidates, and geometric mean-based final ranking from the most to the least stable expression was as follow: RPL5, RPL4, RPS18, RPL8, RPL7, UBE2, RPL7A, GAPDH, RPL36, PPIB, EF1A, ACTB and B-TU. The findings were further validated via relative quantification of metallothionein (MT) transcripts using the stable and unstable reference genes, and expression levels of MT were greatly influenced according to the choice of reference genes. In overall, our data suggest that RPL5 and RPS18, either singly or in combination, are appropriate for normalizing gene expression in developmental samples of this abalone species, whereas ACTB, B-TU and EF1A are less stable and not recommended. In addition, our findings propose that standard deviations in geometric ranking as well as geometric mean itself should also be taken into account for the final selection of reference gene(s). This study could be a useful basis to facilitate the generation of accurate and reliable RT-qPCR data with developmental samples in this abalone species.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2006년도 춘계학술발표논문집
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• pp.608-610
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• 2006

Supply Chain Management(SCM) system is a critical investment that can affect future competitiveness and performance of a company. When adopting a new SCM system, organizations experience increasing difficulty in decision making because information technology is changing so rapidly these days. Therefore, organizations have been looking for industry standards and proven methods of selection that they can utilize to choose the best SCM system. To select an optimum solution, we need to consider a number of different quantitative and qualitative factors such as cost, user interface and convenience, reference site, and so on. In this study, we propose a solution selection model of SCM systems using Fuzzy AHP to maximize the return on investment in information technology. The proposed model can systematically construct the objectives of SCM system selection to support the business goals.

• Asian-Australasian Journal of Animal Sciences
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• 제27권4호
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• pp.471-478
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• 2014

Investigating gene expression of immune cells of whole blood or peripheral blood mononuclear cells (PBMC) under polyinosinic:polycytidylic acid (poly I:C) stimulation is valuable for understanding the immune response of organism to RNA viruses. Quantitative real-time PCR (qRT-PCR) is a standard method for quantification of gene expression studies. However, the reliability of qRT-PCR data critically depends on proper selection of reference genes. In the study, using two different analysis programs, geNorm and NormFinder, we systematically evaluated the gene expression stability of six candidate reference genes (GAPDH, ACTB, B2M, RPL4, TBP, and PPIA) in samples of whole blood and PBMC with or without poly I:C stimulation. Generally, the six candidate genes performed a similar trend of expression stability in the samples of whole blood and PBMC, but more stably expressed in whole blood than in PBMC. geNorm ranked B2M and PPIA as the best combination for gene expression normalization, while according to NormFinder, TBP was ranked as the most stable reference gene, followed by B2M and PPIA. Comprehensively considering the results from the two programs, we recommended using the geometric mean of the three genes, TBP, PPIA and B2M, to normalize the gene expression of whole blood and PBMC with poly I:C stimulation. Our study is the first detailed survey of the gene expression stability in whole blood and PBMC with or without poly I:C stimulation and should be helpful for investigating the molecular mechanism involved in porcine whole blood and PBMC in response to poly I:C stimulation.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1998년도 가을 학술발표회 논문집
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• pp.381-388
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• 1998

This paper describes the development of an expert system designed to help engineers select proper foundation types and construction methods for structures under various subsoil conditions. The system includes geographical and geological data in certain areas of Ulsan and a knowledge base for the selection of foundation types. Geological data, such as boring logs, in the areas were collected and arranged to form the subsoil database in the areas concerned Test borings at 30 holes were carried out for reference and confirmation purposes. The use of this system is twofold. It provides the users with a quick view on the geological situations of the areas concerned, and suggests proper foundation types for the specific spot together with some explanations on the selected foundation types and methods.

• 디지털산업정보학회논문지
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• 제9권4호
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• pp.21-31
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• 2013

It is not easy to control the unstructured digital contents efficiently which are usually created while carrying out the wide scope of managerial activities. Moreover, besides the existing EDMS method, new methodologies including new-type servers and clients like SBC, VDI, thin client, zero client, etc are said to be more efficient for managing digital contents. Usually, digital contents has been created and stored in the dispersed individual computers like laptop or desktop. Today, due to the advent of new technologies and devices for computer systems and network capacity, it's possible to store whole digital contents within centralized storage like EDMS. In this paper, it is shown how digital contents can be controled through selection of which approaches are used for individual users and storage servers. For alternatives, we explained implementation, merits and demerits, selection criteria, etc. And a case of the implementation of digital contents control is shown for the reference of related systems.

• 통상정보연구
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• 제11권3호
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• pp.75-100
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• 2009

With the change of various business environments, needs for the third party logistics(3PL) service are strategically considered for securing core competitiveness of manufacturers in China. Thus, manufacturers not only have worked with 3PL service providers for cutting costs of logistics, but also they are willing to have Win-Win relationship with the 3PL service provider. In this paper, comparing situation and characteristics of both China and developed-countries, especially in the particularity of manufacturing companies in China. The most important thing is that 3PL service providers must be able to manage supply chain of manufacturers with logistic planning abilities and to operate logistics services with logistic infrastructures and IT systems. In the view of long-term development, incubating logistics specialists is also the influencing fact that makes 3PL service providers more competitive with high quality logistics service and infrastructures.

• 한국시뮬레이션학회논문지
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• 제21권2호
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• pp.69-78
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• 2012

본 논문에서는 애드혹 무선 네트워크에서 채널 전송속도를 높일 수 있는 협력통신 기법에서 도움노드를 선정하는 방법에 대한 연구를 수행하였다. 송수신 노드가 RTS/CTS 제어 프레임을 서로 교환한 이후에 도움노드를 선정하는 사후선정 기법을 채용한 참고문헌 연구결과를 컴퓨터 모의실험을 사용하여 성능비교를 수행하기 위해 시뮬레이터를 구현하였다. 성능평가 척도는 시스템 처리량과 채널 액세스 지연시간을 사용하였으며, 통신노드는 모두 지정된 통신영역 내에서 독립적으로 이동하는 모델을 사용하였다. 성능비교와 장단점 분석을 통해 취합된 결과는 성능이 우수한 새로운 도움노드 선정기법을 설계하는데 귀중한 자료가 될 것으로 판단된다.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2018년도 학술발표회
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• pp.151-151
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• 2018

The present study is aimed to quantifying the uncertainty in the general circulation model (GCM) selection and its impacts on hydrology studies in the basins. For this reason, 13 GCMs was selected among the 26 GCM models of the Fifth Assessment Report (AR5) scenarios. Then, the climate data and hydrologic data with two Representative Concentration Pathways (RCPs) of the best model (INMCM4) and worst model (HadGEM2-AO) were compared to understand the uncertainty associated with GCM models. In order to project the runoff, the Precipitation-Runoff Modelling System (PRMS) was driven to simulate daily river discharge by using daily precipitation, maximum and minimum temperature as inputs of this model. For simulating the discharge, the model has been calibrated and validated for daily data. Root mean square error (RMSE) and Nash-Sutcliffe Efficiency (NSE) were applied as evaluation criteria. Then parameters of the model were applied for the periods 2011-2040, and 2070-2099 to project the future discharge the five large basins of South Korea. Then, uncertainty caused by projected temperature, precipitation and runoff changes were compared in seasonal and annual time scale for two future periods and RCPs compared to the reference period (1976-2005). The findings of this study indicated that more caution will be needed for selecting the GCMs and using the results of the climate change analysis.

• 한국컴퓨터산업학회논문지
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• 제3권3호
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• pp.331-340
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• 2002

웹의 세계는 하루가 다르게 확장되고 있다. 이에 따라, 지능형 정보추출 기능이 없다면 우리는 넘쳐나는 데이터 앞에서 더욱 무기력해 질 수밖에 없다. 범용 탐색 엔진을 위한 기존의 웹 검색 기법은 특정 영역이나 특정 키워드에만 집중해야하는 특정 검색 엔진에는 너무 느린 경향이 있다. 본 논문에서는 웹 검색 능력을 개선하는 새 모델을 제시하고 실험하였다. 특정 영역과 관련된 초기의 관련 웹 페이지 집합에서 적절한 웹 페이지들을 선택하는 문제는 웹 검색 속도를 향상시키기 위해 매우 중요할 수 있다. 기준 웹 페이지 선택 기법 DOPS는 선택된 웹 페이지들이 가능한 한 직교성을 갖도록 동적으로 웹 페이지를 선택한다. 또한 새로 정의된 메져를 이용하여 적합한 기준 페이지들의 수도 결정해줄 수 있다. 매우 특화된 영역에 대한 실험을 통해서도, 본 방법은 거의 전문가 수준에 가까이 동작하였다. 전문가들이 초대형 초기 페이지 집합에 대해 일할 수 없다는 점과 그들도 기준 페이지 수의 최적치를 결정하기에 어려움을 느낀 다는 점을 고려하면, 본 방법은 매우 유망하다 할 수 있다. 또한 웹 환경에 강화학습도 적용하도록 하였고, DOPS에 기반을 둔 강화학습 실험을 통해 본 방법이 하이퍼링크 수나 시간 면에서 매우 양호한 결과를 보임을 알 수 있었다.

• 한국정보과학회논문지:정보통신
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• 제37권6호
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• pp.489-493
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• 2010

래터레이션 기반 실내 위치 측위 기법은 단말기와 AP(Anchor Point) 사이의 거리 예측을 위하여 RSS(Received Signal Strength)를 주로 사용한다. 그러나 무선 신호는 시간과 공간에 따라 무작위로 변화하는 특성을 가지므로 RSS를 이용한 거리 예측에서 오류의 발생은 불가피하다. 단말기와 AP사이의 거리 예측 정확도는 단말기 위치 예측 정확도에 많은 영향을 미치게 되므로 기존 기법들은 이를 해결하기 위하여 다수의 AP를 사용하였다. 그러나 많은 실험 결과들은 다수의 AP 사용보다는 경로 손실 모델에 잘 부합하는 RSS 측정 값을 가진 AP 즉 기준 AP 만을 선택하여 이용하는 것이 위치 예측 정확도를 향상시킬 수 있는 방법임을 보였다. 따라서 본 논문에서는 실내 환경에서 단말기의 측위 정확도활 향상시키기 위한 기준 AP 선택 기법과 선택된 기준 AP들을 이용한 적응적 거리 예측 기법을 제안한다. 또한 실내 위치 측위 시스템을 구현하여 다양한 실험 환경에서의 실험함으로써 제안 기법의 타당성을 검증하였다.