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The Cancer-Preventive Potential of Panax ginseng - A Review of Human and Experimental Evidence - (인삼(Panax ginseng) 항암 효과에 관한 문헌고찰 - 실험연구와 역학연구 결과를 중심으로 -)

  • Kim, Joon-Youn;Lee, Duk-Hee;Yun, Taik-Koo;Morgan, Gareth;Vainio, Harri;Shin, Hai-Rim
    • Journal of Preventive Medicine and Public Health
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    • v.33 no.4
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    • pp.383-392
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    • 2000
  • Objective : We have reviewed the potential cancer preventive and other relevant properties of Panax ginseng C. A. Meyer, which has been traditionally used as a natural tonic in oriental countries. Data identification and study selection: Publications on Panax ginseng and its relation to cancer were obtained from the Medline database (1983-2000) and by checking reference lists to find earlier reports. The reports cover experimental models and human studies on cancer-preventive activity, carcinogenicity and other beneficial or adverse effects. In addition, possible mechanisms of chemoprevention by ginseng were also considered. Results : Published results from a cohort and two case-control studies in Korea suggest that the intake of ginseng may reduce the risk of several types of cancer. When ginseng was tested in animal models, a reduction in cancer incidence and multiplicity at various sites was noted. Panax ginseng and its chemical constituents have been tested for their inhibiting effect on putative carcinogenesis mechanisms (e.g., cell proliferation and apoptosis, immunosurveillance, angiogenesis); in most experiments inhibitory effects were found. Conclusion : While Panax ginseng C. A. Meyer has shown cancer preventive effects both in experimental models and in epidemiological studies, the evidence is currently not conclusive as to its cancer-preventive activity in humans. The available evidence warrants further research into the possible role of ginseng in the prevention of human cancer and carcinogenesis.

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An analytic solution for the stirling engines with saw-toothed piston motions in adiabatic cylinders (단열실린더내에서 톱날파형 피스톤운동을 하는 스터링기관에 대한 해석적인 해)

  • 유호선
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.12 no.5
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    • pp.1197-1205
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    • 1988
  • An analytical method to predict qualitative performance characteristics of the Stirling Engines in the preliminary design stages is investigated. Both the expansion and the compression cylinder are treated as adiabatic and piston motions are approximated as saw-toothed waves. Basic equations which were originally proposed by Finkelstein consist of mass conservation and energy balances for each adiabatic cylinder. The approximation on piston motions and physical conditions make it possible to divide an engine cycle into four fundamental processes. In each process, first, pressure can be expressed as a function of the crank angle by solving a nonlinear first order ordinary differential equation and other thermodynamic variables are determined in turn. Application of the cyclic steady condition to the whole processes can complete a cycle. Also, further analysis results in analytic expressions for cyclic work and heat transfer in terms of the engine parameters and thermodynamic variables at boundary points. The results are expected useful as a quick reference for the engine performances. Finally, the present method can be applied to the other adiabatic analyses on the Stirling Engines with piece wise linear piston motions, if mass variations are predictable.

The Reconstructive Method for The Enhancement of Depth Resolution for Acoustic Image using the Spatial Frequency Response in NPPs' Material (NPP 매질내에서 공간주파수 응답을 이용한 초음파 영상의 깊이 분해능 개선을 위한 복원 방법)

  • Koo, Gil-mo;Kim, Hyun;Park, In-ho
    • Journal of Korea Multimedia Society
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    • v.5 no.4
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    • pp.426-433
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    • 2002
  • In this paper, we have studied the images which have been reconstructed by using combination of images acquired by the variation of operating frequency. When inner images have been reconstructed, they have been superposed by the surface state effect. In this case, the images of the phase object can be enhanced by the contrast of inner images. In this experiment, there are two kinds of specimens, one is a reference block haying 1/4T, 1/2T, 3/4T side drilled holes as main run piping material 111 the steam generator in NPP(Neuclear Power Plant)s and the another is a part of a hemisphere type specimen having about 1-2㎜ distance gap. It has been shown that the two results of defect shapes have better than before in this processing and phase contrast grow about twice. And we have constructed the acoustic microscope by using a quadrature detector that enables to acquire the amplitude and phase of the reflected signal simultaneously Further more ore have studied the reconstruction method of the amplitude and phase images and the enhancement method of the defect images contrast.

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Research on prefabricated concrete beam-column joint with high strength bolt-end plate

  • Shufeng, Li;Di, Zhao;Qingning, Li;Huajing, Zhao;Jiaolei, Zhang;Dawei, Yuan
    • Structural Engineering and Mechanics
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    • v.74 no.3
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    • pp.395-406
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    • 2020
  • Many prefabricated concrete frame joints have been proposed, and most of them showed good seismic performance. However, there are still some limitations in the proposed fabricated joints. For example, for prefabricated prestressed concrete joints, prefabricated beams and prefabricated columns are assembled as a whole by the pre-stressed steel bar and steel strand in the beams, which brings some troubles to the construction, and the reinforcement in the core area of the joints is complex, and the mechanical mechanism is not clear. Based on the current research results, a new type of fabricated joint of prestressed concrete beams and confined concrete columns is proposed. To study the seismic performance of the joint, the quasi-static test is carried out. The test results show that the nodes exhibit good ductility and energy dissipation. According to the experimental fitting method and the "fixed point pointing" law, the resilience model of this kind of nodes is established, and compared with the experimental results, the two agree well, which can provides a certain reference for elasto-plastic seismic response analysis of this type of structure. Besides, based on the analysis of the factors affecting the shear capacity of the node core area, the formula of shear capacity of the core area of the node is proposed, and the theoretical values of the formula are consistent with the experimental value.

Global Utopia and Local Anxiety on the Stage of the Korean Musical

  • Choi, Sung Hee
    • Cross-Cultural Studies
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    • v.36
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    • pp.123-147
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    • 2014
  • The purpose of this essay is three-fold: to trace the genealogy of the Korean musical, which ever since its inception in the 1960s has been seeking to modernize Korean theater with Broadway as a constant role model; to investigate how the national and the global conflict and are conflated in the form of the Korean musical in the process of its (dis)identification with Broadway; and to examine how its intercultural translations reveal and reflect the dilemma and ambivalence posed by globalization in our era. Drawing on Richard Dyer's signature article Entertainment and Utopia, I analyze how the Korean musical manifests and conduits competing utopian impulses of Korean/Global audiences. I also attempt to problematize the formulaic notion of Broadway musicalsthe Superior Other!which implies a global hegemony that does not, in fact, exist because the boundary between the global and the local as well as the power dynamics of global culture are not fixed but constantly moving and changing. Today's musical scene in Korea shows interesting reversals from the 1990s, when Korean producers were eager to debut on Broadway and impress American audiences. Korean producers no longer look up to Broadway as a final destination; instead they want to make Seoul a new Broadway. They import Broadway musicals and turn them into Korean shows. The glamor of Broadway is no longer the main attraction of musicals in Korea. What young audiences look for most is the glamor of K-pop idols and utopian feelings of abundance, energy, intensity, transparency and community, which they can experience live in the musical with their favorite stars right in front of their eyes. In conclusion, I delve into the complex dynamics of recent Korean musicals with Thomas Friedman's theory of Globalization 3.0 as reference. The binary formula of Global/America versus Local/Korea cannot be applied to the dynamic and intercultural musical scene of today. Globalization is not a uniform phenomenon but rather a twofold (multifold) process of global domination and dissemination, in which the global and the local conflict and are conflated constantly. As this study tries to illuminate, the Korean musical has evolved in a huge net of interdependences between the global and the local with a range of sources, powers and influences.

Finding Optimal Mass Flow Rate of Liquid Rocket Engine Using Generic Algorithm (유전알고리즘을 이용한 액체로켓엔진 최적 유량 결정)

  • Lee, Sang-Bok;Jang, Jun-Yeoung;Kim, Wan-Jo;Kim, Young-Ho;Roh, Tae-Seoung;Choi, Dong-Whan
    • Proceedings of the Korean Society of Propulsion Engineers Conference
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    • 2011.04a
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    • pp.93-96
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    • 2011
  • A genetic algorithm (GA) has been employed to optimize the major design variables of the liquid rocket engine. Mass flow rate to the main thrust chamber, mass flow rate to the gas generator and chamber pressure have been selected as design variables. The target engine is the open gas generator cycle using the LO2/RP-1 propellant. The objective function of design optimization is to maximize the specific impulse with condition of energy balance between the pump and the turbine. The properties of the combustion chamber have been obtained from CEA2. Pump & turbine efficiencies and properties of the gas generator have been modeled mathematically from reference data. The result shows 3~4% errors for the specific impulse and 2~6% errors for the pump power of the gas generator cycle compared to references.

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Analysis of Heat Loss with Mirror Array and Receiver Shapes on the Dish Solar Collector (반사경 배치 및 흡수기 형상에 따른 접시형 태양열 집열기의 열손실 해석)

  • Seo, Joo-Hyun;Ma, Dae-Sung;Kim, Yong;Kang, Yong-Heack;Seo, Tae-Beom
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.20 no.1
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    • pp.35-41
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    • 2008
  • The radiative heat loss from a receiver of a dish solar collector is numerically investigated. The dish solar collector considered in this paper consists of a receiver and multi-faceted mirrors. In order to investigate the performance comparison of dish solar collectors, six different mirror arrays and four different receivers are considered. A parabolic- shaped perfect mirror of which diameter is 1.40 m is considered as the reference for the mirror arrays. The other mirror arrays which consist of twelve identical parabolic-shaped mirror facets of which diameter are 0.405 m are suggested for comparison. Their reflecting areas, which are 1.545 $m^{2}$, are the same. Four different receiver shapes are a conical, a dome, a cylindrical, and a unicorn type. The radiative properties of the mirror surfaces and the receiver surfaces may vary the thermal performance of the dish solar collector so that various surface properties are considered. In order to calculate the radiative heat loss in the receiver, two kinds of methods are used. The Net Radiation Method that is based on the radiation heat balance on the surface is used to calculate the radiation heat transfer rate from the inside surface of the receiver to the environment. The Monte-Carlo Method that is the statistical approach is adopted to predict the radiation heat transfer rate from the reflector to the receiver. The collector efficiency is defined as the results of the optical efficiency and the receiver efficiency. Based on the calculation, the unicorn type has the best performance in receiver shapes and the STAR has the best performance in mirror arrays except the perfect mirror.

Absolute Activity Measurement of $^{137}Cs$ Solution by the Tracer Method (추적자 방법에 의한 $^{137}Cs$용액의 방사능 절대측정)

  • Park, Tae-Soon;Oh, Pil-Jae;Hwang, Sun-Tae;Lee, Kun-Jai
    • Nuclear Engineering and Technology
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    • v.19 no.2
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    • pp.107-114
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    • 1987
  • Using a solution of $^{137}$ Cs as a tracer, radioactivity of a $^{137}$ Cs solution is measured by coincidence and anticoincidence counting methods. Sample sources in this study are fabricated by mixing $^{137}$ Cs with tracer, and the mixing ratios are 1/3 and 1/5, respectively in coincidence and anticoincidence methods. Specific activities of a $^{137}$ Cs solution are calculated by means of f-channel low energy threshold level variation and efficiency extrapolation. The results obtained by coincidence and anticoincidence counting methods are 552.78 kBq/g and 554.32kBq/g, respectively on the reference date and the combined uncertainties are 1.60kBq/g and 1.51kBq/g for each method. These two results show a good agreement within the uncertainty range.

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A Study of the Phase Relations Between the Reflected and Transmitted Light Waves at a Beam Splitter and Their Application to Interferometers (빔가르개에서 반사광과 투과광 사이의 위상 관계 고찰 및 간섭계 적용)

  • Son, Byungwoo;Choi, Hee Joo;Park, Ju Eun;Cha, Myoungsik
    • Korean Journal of Optics and Photonics
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    • v.26 no.2
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    • pp.103-109
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    • 2015
  • In an amplitude-splitting interferometer, a beam splitter divides an input beam into two parts, which are superposed after propagating along separate paths, producing an interference effect. We have investigated the phase relation between the reflected and transmitted light waves at BS's made of lossless dielectric stacks. If we define the phases with proper reference planes, a definite phase relation exists, irrespective of the detailed structure of the layers in the BS. Although this results from the generalized Stokes relations, we have verified it numerically for two representative BS's with symmetric and asymmetric layer structures respectively. When we applied the phase relation to interferometers, we could determine the superposition state of the output beam (either constructive or destructive interference) for a general BS, and could verify that the light's energy was conserved.

Study and Evaluation of Tourism Websites based on User Perspective

  • Shrestha, Deepanjal;Wenan, Tan;Rajkarnikar, Neesha;Shrestha, Deepmala;Jeong, Seung Ryul
    • Journal of Internet Computing and Services
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    • v.22 no.4
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    • pp.65-82
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    • 2021
  • A well-designed website is mandatory for good marketing and proper tourism business. This research considers Nepal as a domain of study and specifically explores welcomenepal.com, the official tourism portal as a reference for the study. The work is based on the study of the existing literature, user-survey, and technical testing of the website using open-source testing tools to identify user perspective, design issues, website architecture and design quality of the tourism website. A population size of 400 respondents, which consist of both domestic and international tourist, are considered for the survey. Data is received from 360 respondents, which is analyzed using statistical tests like Cronbach's alpha, Pearson's correlation, cross-tabulations, bars charts and graphs to draw inferences and consclusion. The software-based test results serve as another important parameter for the evaluation of the current official website. This study brings out core needs of the tourist in terms of expectations from a tourism website and access technical quality of the current portal to provide necessary feedback and suggestions. The government officials, business houses, and web designers can utilize this work as a knowledge base to build tourism websites, which are user-centric. Further, the work is specifically important for Nepal government and tourism officials to identify shortcomings in their current website and make improvements for better design and user adaptability in future.