• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.20 no.9
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• pp.11-17
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• 2006

We have theoretically investigated the effects of the interplay between the driving voltage of Mach-Zehnder(MZ) modulators and the bandwidth of low-pass filters(LPF) in 10[Gb/s] duobinary modulation systems. For the change of driving voltage ratios(driving voltage/switching voltage), the transmission performance has been evaluated over 200[km] of single-mode fiber(SMF) systems. For driving voltage ratios with smaller than 100[%], the transmission performance has been maintained and greatly affected by the bandwidth of LPFs than the driving voltage. For driving voltage ratios with larger than 100[%], the transmission performance has been degraded and is not sensitive to the bandwidth of LPFs. To see the limitation of driving voltage, we have reduced the driving voltage ratio to 50[%]. Our results suggest that 10[Gb/s] duobinary signals with driving voltage ratio with smaller than 100[%] have been transmitted over 200[km] SMF within 2[dB] power penalty without dispersion compensation. For the driving voltage ratio with 50[%], we have verified that the transmission performance was maintained.

• Journal of Microbiology and Biotechnology
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• v.13 no.3
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• pp.444-450
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• 2003

In order to develop an effective means to treat P. aeruginosa infections, we have purified P. aeruginosa outer membrane proteins (OMPs)-specific human IgG antibody. In this study, we investigated the protective activity of the purified anti-OMPs IgC against P. aeruginosa infection in a rabbit endophthalmitis model. Rabbits were inoculated by an intravitreal injection with P. aeruginosa, and treated with a single dose of 1 mg anti-P. aeruginosa OMPs IgG. All the control rabbits predominantly developed edematous responses and opacity in the eyes, but the rabbits treated with the antibody showed only very limited degree of edema. Aliquots of the vitreous humor were extracted and analyzed for the number of viable bacteria and endotoxin level. The results showed that the anti-OMPs IgC significantly reduced the bacterial count compared with the control group, and that the endotoxin level of the vitreous from the IgG-treated rabbits was more than 70-fold lower 6 h after the administration than the control animals. These data suggested that the anti-P. aeruginosa OMPs IgG is effective in inhibiting the bacterial growth and thereby in reducing endotoxin levels in the vitreous, warranting further development of the anti-P. aeruginosa OMPs IgG as a therapeutic means for treating Pseudomonas endophthalmitis.

• Environmental Analysis Health and Toxicology
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• v.15 no.3
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• pp.61-67
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• 2000

Toxic lesions of styrene in the Japanese Medaka (Oryzias latipes) were compared with those of styrene oxide, the active metabolite of styrene, using embryo-larval assays. The developmental stages of Japanese Medaka (Oryzias latipes) treated with both chemicals were not altered and progressed normally. However, styrene oxide was more toxic than styrene in terms of causing death and lesions . High concentrations of styrene (higher than 4.9 ppm) and styrene oxide (higher than 2.4 ppm), resulting in more than 50% mortality, caused similar lesions of cardiovascular system, craniofacial bone formation and spinal deformities, although a number of lesions were not observed by both chemicals . In the group treated with styrene, eyeball sizes and intereye distances were reduced, while, in the group treated with styrene oxide , the eyes and eye cups were not developed and two eyes were sometimes fused. In addition, styrene oxide caused the lesion which involved the posterior brain and brain stem were herniated through the spinal cord . The noticeable difference of toxic symptoms between these two chemicals was the time of onset. Toxicities of cardiovascular system and craniofacial bone formation appeared on day 3 of development in styrene oxide treated group, but, styrene treated group staned to show hemorrhages on day 3 and the craniofacial malformation were appeared on day 5, These differences between two chemicals may be due to the metabolism of styrene to styrene oxide, the reactive intermediate.

• Journal of Pharmaceutical Investigation
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• v.24 no.3
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• pp.59-66
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• 1994

The objective of this study was to determine the influence of drug lipophilicity on the extent of ocular and systemic absorption following topical solution instillation in the pigmented rabbit. ${\beta}-Blockers$ of various lipophilicity were chosen as model drugs, $25\;{\mu}l$ of a 15 mM drug solution in isotonic pH 7.4 buffer was instilled, and ocular tissue and plasma drug concentrations were monitored. Ocular absorption was apparently increased in all eye tissues, but non-corneal absorption ratio was decreased by increasing of drug lipophilicity. Systemic bioavailability was ranged from 61% for atenolol to 100% for timolol, and at least 50% of the systemically absorbed drug reached the blood stream from the nasal mucosa. Occluding the nasolacrimal duct for 5 min reduced the extent of systemic absorption of timolol and levobunolol, but did not do so for atenolol and betaxolol. Taken together, the ocular absorption of topically applied ophthalmic drugs would be modest for lipophilic drugs. By contrast, the systemic bioavailability would be modest for drugs at the extremes of lipophilicity, and the nasal contribution to systemically absorbed drug diminished with increasing of drug lipophilicity.

• International Journal of Automotive Technology
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• v.7 no.5
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• pp.603-608
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• 2006

As an important and relatively easy to implement technology for realizing Intelligent Transportation Systems(ITS), Adaptive Cruise Control(ACC) automatically adjusts vehicle speed and distance to a preceding vehicle, thus enhancing driver comfort and safety. One of the key issues associated with ACC development is usability and user acceptance. Control parameters in ACC should be optimized in such a way that the system does not conflict with driving behavior of the driver and further that the driver feels comfortable with ACC. A driving simulator is a comprehensive research tool that can be applied to various human factor studies and vehicle system development in a safe and controlled environment. This study investigated driving behavior with ACC for drivers with different driving styles using the driving simulator. The ACC simulation system was implemented on the simulator and its performance was evaluated first. The Driving Style Questionnaire(DSQ) was used to classify the driving styles of the drivers in the simulator experiment. The experiment results show that, when driving with ACC, preferred headway-time was 1.5 seconds regardless of the driving styles, implying consistency in driving speed and safe distance. However, the lane keeping ability reduced, showing the larger deviation in vehicle lateral position and larger head and eye movement. It is suggested that integration of ACC and lateral control can enhance driver safety and comfort even further.

• Journal of environmental and Sanitary engineering
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• v.21 no.4 s.62
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• pp.1-10
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• 2006

This research is based on self-filling survey which 220 dental hygienists who work in seoul participated on July 2006 through August 2006. This survey was analyzed the experience item and occurred time of the symptoms and the time of acute and vanish of the symptoms that dental office's working environment effects on physical subjective symptom. We suggest a plan to minimizing physical subjective symptom for health manage of dental hygienist. We found out the fact that dental hygienists were unsatisfied with hospital air condition and this polluted air condition cause them physical subjective symptom in work place. As follows analyzed results ventilation time is below the 3-times a day, this may be have some trouble in indoor air quality. The experience the symptoms level is higher then non-experience level in "Fatigue and sleepiness", "Dorsalgia, omarthralgia, cervicodynia", "Hypersensitivity", "Dry eye, itch, smarting", "Headaches" and a subjective symptom is occurred at after 11:00(am) more then 60%, 50% of the dental hygienist. This experience the symptom' pain is vanished after the work and reduced when go out the office and building, respectively. The ratio of the experience the symptoms and starting time the symptoms is anywhere from 12 noon to 4 pm (73.2%) in a day. The time of acute pain the symptoms is anywhere from 12 noon to 4 pm (78.7%) refer to the individual characteristics and work environment.

• Journal of Sensor Science and Technology
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• v.23 no.2
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• pp.99-104
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• 2014

Sensor arrays based on chemical sensors produce multidimensional patterns of data that may be used discriminate between different chemicals. For the human observer, visualization of multidimensional data is difficult, since the eye and brain process visual information in two or three dimensions. To devise a simple means of data inspection from the response of sensor arrays, PCA (Principal Component Analysis) or Sammon's nonlinear mapping technique can be applied. The PCA, which is a well-known statistical method and widely used in data analysis, has disadvantages including data distortion and the axes for plotting the dimensionally reduced data have no physical meaning in terms of how different one cluster is from another. In this paper, we have investigated two techniques and proposed a combination technique of PCA and nonlinear Sammom mapping for visualization of multidimensional patterns to two dimensions using data sets from odor sensing system. We conclude the combination technique has shown more advantages comparing with the PCA and Sammon nonlinear technique individually.

• Food Science of Animal Resources
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• v.23 no.4
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• pp.315-320
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• 2003

A total of 240 crossbred(Landrace ${\times}$ Yorkshire ${\times}$ Duroc) pigs were housed from 70 kg live weight and slaughtered at weights of 95, 105, 115 and 125 kg. The left side loins of carcass were obtained at 24 hr postmortem to measure pork quality. There were significant differences(p<0.01) in eye muscle area of pork loins between the slaughter weights of 95 and 105 kg. However, no differences were observed in pork than 105 kg of slaughter weight. Ultimate pH values were decreased with increasing slaughter weight and cooking loss was also reduced(p<0.01) at the heavier weights. Slaughter weights did not affect the shear force and intramuscular fat. However, dry matter(DM) and crude protein(CP) contents of loin were increased, and cooking loss and sarcomere length were decreased with increasing slaughter weight. The lightness(L$^{*}$) and redness(a$^{*}$) of pork loin were increased with increasing slaughter weight. Results suggested that pork quality may be improved when pig slaughter weight is increased from 95 to 125 kg.

• Korean Journal of Acupuncture
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• v.32 no.2
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• pp.75-79
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• 2015

Objectives : This study is to report one case of the diabetic ophthalmoplegia by acupuncture at Jok-Gwoleum-Gan-Gyeong. Methods : The patient was treated with acupuncture and herbal medicine for about 5 weeks. We evaluated the results of the treatment by observing the patient's symptoms. Results : After acupuncture the patient's symptoms such as strabismus, headache, ptosis, Rt eye pain and discomfort and both shoulder pain were considerably reduced. Conclusions : These results support that acupuncture at Jok-Gwoleum-Gan-Gyeong can have a meaningful effect in improving symptoms of diabetic ophthalmoplegia.

• Journal of the Korean Applied Science and Technology
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• v.27 no.4
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• pp.501-507
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• 2010

In this study, we evaluate the anti-microbiological activity of paraben in eye shadows that are composed of pigments and oil binders using various analytical methods and microbiological tests. Paraben does not show the microbiological activity properly when it was used with Nylon SP$^{(R)}$ 10, Talc RF SSA$^{(R)}$, OMC Talc AS$^{(R)}$ and $BaSO_4$. In the test of fungi, Nylon SP$^{(R)}$ 10 causes the decrease of microbiological activity regardless of the type of oil binders. The pigment of Mango violet also causes the decrease of microbiological activity when ester oil binder was used. Regardless of the type of oil binder, samples containing nylon SP 10, 0.15% of methyl paraben and 0.05% of propyl paraben had not been able to maintain microbiological activity only if the concentration of parabens were increased. Trace amounts of metal ions present in pigments reduced the activity of preservatives by inactivation of hydroxyl group of paraben. It is thought that swollen nylon SP 10 in ester oil increase the absorption or interaction of parabens and swollen nylon powder causes the inactivation of paraben.