• Title/Summary/Keyword: recovery of function

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An experimental study on the myocardial protection effect of the methylprednisolone mixed GIK solution (Methylprednisolone을 첨가한 GIK용액의 심근보호효과에 관한 실험적 연구)

  • 유시원
    • Journal of Chest Surgery
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    • v.17 no.4
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    • pp.574-586
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    • 1984
  • Although corticosteroid have been shown to stabilize lysosomal membranes and prevent release of hydrolytic enzymes, the mechanism of membrane stabilization remains obscure. This study described functional assessment of efficiency of methylprednisolone in GIK solution by using a isolated Rat Heart Model. Isolated rat heart were subjected to a 2-minute period of coronary infusion with a cold GIK or methylprednisolone mixed cold GIK solution immediately before and also at the midpoint of a 60-minute period of hypothermic [$10{\pm}1^{\circ}C$] ischemic arrest. The result of this were as follow: 1.Spontaneous heart beat after ischemic arrest occurred 11 second later after Langendorffs reperfusion in the methylprednisolone mixed GIK group and 14 second later in the control group. 2.The percentage of recoveries of heart rate at 30 minute after postischemic working heart perfusion was 88.6\ulcorner.6% in the methylprednisolone mixed GIK group. This percentage of recovery was not significantly greater than the control group. 3.The percentage of heart function at 30 minute after postischemic working heart perfusion were; peak aortic pressure $90.8{\pm}4.5%$ coronary flow $87.5{\pm}1.45$ and aortic flow $74.9{\pm}11.8%$ in the methylprednisolone mixed GIK group. This percentage of recovery was significantly greater than the control group. [p<0.05]

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Impact identification and localization using a sample-force-dictionary - General Theory and its applications to beam structures

  • Ginsberg, Daniel;Fritzen, Claus-Peter
    • Structural Monitoring and Maintenance
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    • v.3 no.3
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    • pp.195-214
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    • 2016
  • Monitoring of impact loads is a very important technique in the field of structural health monitoring (SHM). However, in most cases it is not possible to measure impact events directly, so they need to be reconstructed. Impact load reconstruction refers to the problem of estimating an input to a dynamic system when the system output and the impulse response function are usually known. Generally this leads to a so called ill-posed inverse problem. It is reasonable to use prior knowledge of the force in order to develop more suitable reconstruction strategies and to increase accuracy. An impact event is characterized by a short time duration and a spatial concentration. Moreover the force time history of an impact has a specific shape, which also can be taken into account. In this contribution these properties of the external force are employed to create a sample-force-dictionary and thus to transform the ill-posed problem into a sparse recovery task. The sparse solution is acquired by solving a minimization problem known as basis pursuit denoising (BPDN). The reconstruction approach shown here is capable to estimate simultaneously the magnitude of the impact and the impact location, with a minimum number of accelerometers. The possibility of reconstructing the impact based on a noisy output signal is first demonstrated with simulated measurements of a simple beam structure. Then an experimental investigation of a real beam is performed.

The Effect of Visual Biofeedback Exercise on the Recovery of Balance in Stroke Patients (시각적 바이오피드백 균형 훈련이 뇌졸중 환자의 균형 회복에 미치는 영향)

  • Kim, Jae-Yong;Kim, Dae-Kyung
    • PNF and Movement
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    • v.15 no.2
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    • pp.201-208
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    • 2017
  • Purpose: The purpose of this study is to determine the effects of visual biofeedback training on the recovery of balance function in stroke patients. Methods: A total of 30 patients with stroke were chosen as the subjects of this study. The subjects were randomly divided into either the visual biofeedback balance training group (experimental group; n=15) or the general balance training group (control group; n=15). The visual biofeedback balance training and general balance training were implemented for 30 minutes a day, three times a week, for a total of four weeks. The subjects' balance ability was measured before and after the interventions. Results: The shift length and surface area of the center of the body decreased in both the experimental group and the control group, with the difference being statistically significant. The shift length and surface area of the center of the body both decreased more in the experimental group than in the control group, and there was a statistically significant between-group difference. Conclusion: The experimental group showed a greater improvement in terms of the balance ability of patients with stroke than the control group. Therefore, we believe that visual biofeedback balance training can be effectively applied for the improvement of balance ability in patients with stroke.

Study on the HDDR Characteristics of the Nd-Fe(-Co)-B(-Ga-Zr)-type Alloys

  • Shon, S.W.;Kwon, H.W.;Kang, D.I.;Kim, Yoon.B.;Jeung, W.Y.
    • Journal of Magnetics
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    • v.4 no.4
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    • pp.131-135
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    • 1999
  • The HDDR characteristics of the Nd-Fe-B-type isotropic and anisotropic HDDR alloys were investigated using three types of alloys: alloy A $(Nd_{12.6}Fe_{81.4}B_6), alloy B (Nd_{12.6}Fe_{81.3}B_6Zr_{0.1}), and alloy C (Nd_{12.6}Fe_{68.8}Co_{11.5}B_6Ga_{1.0}Zr_{0.1}$). The alloy A is featured with the isotropic HDDR character, while alloy B and C are featured with the anisotropic HDDR character. Hydrogenation and disproportionation characteristics of the alloys were examined using DTA under hydrogen gas. Recombination characteristics of the alloys were examined by observing the coercivity variation as a function of recombination time. The present study revealed that the alloy C exhibits slightly higher hydrogenation and disproportionation temperatures compared to the alloy A and B. Recombination of the anisotropic alloy B and C takes place more rapidly with respect to the isotropic alloy A. The intrinsic coercivities of the recombined materials rapidly increased with increasing the recombination time and then showed a peak, after which the coercivities decreased gradually. The degraded coercivity was, however, recovered significantly on prolonged recombination treatment. Compared with the isotropic HDDR alloy A the anisotropic HDDR alloy B and C are notable for their greater recovery of coercivity. The significant recovery of coercivity was accounted for the in terms of the development of well-defined smooth grain boundary between the recombined grains on prolonged recombination.

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Determining Optimal Locations of an Artificial Recharge Well using an Optimization-coupled Groundwater Flow Model (지하수 모델링 기법을 이용한 인공함양정 최적 위치 평가)

  • Lee, Hyeonju;Koo, Min-Ho;Kim, Yongcheol
    • Journal of Soil and Groundwater Environment
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    • v.19 no.3
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    • pp.66-81
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    • 2014
  • A Fortran program was developed to determine the optimal locations of an artificial recharge well. Three objective functions were considered: (1) maximizing the recovery rates, (2) maximizing the injection rates, and (3) minimizing the coefficient of variation of the increased pumping rates. We also suggested a new aggregate objective function which combined the first and the third objective functions. The model results showed that locating the injection well inside the cluster of pumping wells was desirable if either the recovery or the injection rate was taken into account. However, the injection well located outside the cluster evenly increased the pumping rates in existing pumping wells. Therefore, for clustered pumping wells, installing an injection well at the center or the upstream of the pumping wells seems beneficial. For linear arrangement of pumping wells parallel to the constant head boundary, locating the injection well in the upstream was recommended. On the contrary, in case of the linear arrangement perpendicular to the constant head boundary, the injection well installed on both sides of the central part of the pumping wells was preferable.

Analysis of Postural Stability and Daily Energy Expenditure to Manage Tumor Patients' Functional Expectation

  • Caliskan, Emrah;Saygi, Evrim Karadag;Gencer, Zeynep Kardelen;Kurtel, Hizir;Erol, Bulent
    • Clinics in Orthopedic Surgery
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    • v.10 no.4
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    • pp.491-499
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    • 2018
  • Background: Advances in surgical techniques, implant technology, radiotherapy, and chemotherapy have increased the recovery chances of patients with bone sarcomas. Accordingly, patients' expectations on life quality have also increased, highlighting the importance of objective evaluation of the functional results of reconstruction. Methods: Thirteen patients with distal femoral endoprosthesis, who had been followed for an average of 2.9 years were evaluated. Postural stability, daily energy expenditure, muscle power, and range of motion were the four parameters analyzed in this study. The Musculoskeletal Tumor Society (MSTS) score and Toronto Extremity Salvage Score (TESS) were used to assess postoperative function and examine correlations with other parameters. Results: Patients had sedentary activities in 84% of their daily lives. They exhibited a slower speed in the walk across test and a higher sway velocity in the sit-to-stand test (p = 0.005). MSTS scores were significantly correlated with the daily energy expenditure and walking speed. Conclusions: Objective functional results acquired from various clinics will provide significant data to compare reconstruction techniques, rehabilitation protocols, and surgical techniques. In this way, it will be possible to satisfy the expectations of patients that increase in relation to enhanced recovery.

An Analysis of the Educational Training Program of Seoul Fire Academy through AHP for the Strengthening of Fire Fighters' Safety Function (소방조직의 안전기능강화를 위한 AHP를 활용한 서울특별시소방학교 교육훈련프로그램 분석)

  • Kim, Jin-Geun;Park, Chan-Seok
    • Proceedings of the Safety Management and Science Conference
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    • 2013.11a
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    • pp.299-320
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    • 2013
  • In recent years, the surroundings of Fire have rapidly changed and citizens need for Fire have been demanding very high. Under these situations, in order for satisfaction to all these demands, Seoul Metropolitan Government Fire Academy(SFA) have only to improve its educational training program as the fire educational training center in Korea. The purpose of this study is to scrutinize current educational training program of SFA and measure the relative weight among the hierarchy of disaster management(prevention and mitigation-prepare dness-response-recovery) by using the Analytic Hierarchy Process(AHP). The result of this study presents that how many hours must be allocated and set the educational training program with scientific and systematic way of AHP compared the current program of SFA in 2013. And This study is applied to increase access and comprehension about the AHP and will be able to present guideline for the selection of optimal the educational training of SFA to serve Seoul citizens the best Fire services.

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Effect of Combination Electroacupuncture and Tenuigenin on the Migration and Differentiation of Mesenchymal Stem Cells following Ischemic Stroke

  • Jae Ho Lee;Byung Tae Choi;Hwa Kyoung Shin
    • Journal of Pharmacopuncture
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    • v.26 no.4
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    • pp.357-365
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    • 2023
  • Objectives: Since stroke is a serious health issue, novel therapeutic strategies are required. In a mouse model of ischemic stroke, this study analyzed the potential of electroacupuncture (EA) and tenuigenin (TE) to improve the efficacy of human mesenchymal stem cell (hMSC) transplantation. Methods: Middle cerebral artery occlusion (MCAO) with reperfusion was used to generate ischemic stroke. Forty-eight male C57BL/6 mice were randomly divided into five groups: control, MCAO-operated, MCAO-EA, MCAO-TE, or MCAO + EA + TE. Subsequently, hMSCs were transplanted into the ischemic region and EA, TE, or the combination was administered. Behavior assessments and immunohistochemistry were conducted to evaluate motor and cognitive recovery and hMSCs survival, migration, and differentiation. Results: The combined treatment of EA and TE exhibited enhanced hMSCs survival, migration and differentiation into neural cell lineages while suppressing astrocyte formation. Immunohistochemistry demonstrated increased neurogenesis through hMSCs transplantation in the ischemic brain. Immediate behavioral improvements were not significantly different between groups, but there was a gradual recovery in motor and cognitive function over time. Conclusion: These findings highlight the potential of EA and TE co-treatment as a therapeutic strategy for ischemic stroke, opening avenues for further research to optimize treatment protocols and elucidate underlying mechanisms.

Recovery of Etching Damage of Etched PZT Thin Film by Inductively Coupled Plasma (유도결합 플라즈마에 의해 식각된 PZT 박막의 식각 Damage 개선)

  • 강명구;김경태;김창일
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.14 no.7
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    • pp.551-556
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    • 2001
  • In this work, the recovery of etching damage in the etched PZT thin film with $O_2$ annealing has been studied. The PZT thin films were etched as a function of Cl$_2$/Ar and additive CF$_4$ into Cl$_2$(80%) /Ar(20%). the etch rates of PZT thin films were 1600$\AA$/min at Cl$_2$(80%)/Ar(20%) and 1970 $\AA$/min at 30% additive Cf$_4$ into Cl$_2$(80%)/Ar(20%). In order to recover the characteristics of etched PZT thin films, the etched PZT thin films were annealed in $O_2$ atmosphere at various temperatures. From the hysteresis curves, ferroelectrical properties are improved by $O_2$ annealing process. The improvement of ferroelectric behavior is consistent with the increase of the (100) and (200) PZT phase revealed by x-ray diffraction (XRD). From x-ray photoelectron spectroscopy (XPS) analysis, intensities of Pb-O, Zr-O and Ti-O peak increase and the chemical residue peak is reduced by $O_2$ annealing. From the atomic force microscopy (AFM) images. it shows that the surface morphology of re-annealed PZT thin films after etching is improved.

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The Effect of Muscle Reeducation Training on Recovery and Function in People with Acute Facial Nerve Paralysis (근재교육훈련이 급성안면신경마비 환자의 안면마비 회복정도와 기능에 미치는 효과)

  • Park, Sang-Kyu;Shin, Won-Seob
    • The Journal of Korean Physical Therapy
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    • v.26 no.4
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    • pp.240-248
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    • 2014
  • Purpose: The purpose of study was to determine the effects of muscle reeducation training in patients with acute facial nerve paralysis. Methods: Thirty patients were randomly assigned to either the experimental group (n=15) or the control group (n=15). The experimental group received muscle reeducation training for 20 minutes after electrotherapy and the control group received conventional electrotherapy for only 40 minutes. Therapeutic intervention for each group was performed four times per week for four weeks. The patients were measured for recovery of paralysis using the House-Brackmann Grading System (H-B grade), the Movement Distance of Mouth, Nasolabial Angle (NA), and Facial Disability Index (FDI). Results: In within group comparison, the experimental group showed significant improvements for all variables (p<0.01). In comparison between two groups, the experimental group showed relatively greater significant improvements for all variables (p<0.01). Conclusion: These findings suggest that muscle reeducation training is more effective than conventional therapy in improving the condition of patients with facial nerve paralysis. In particular, the results of this study indicate that muscle reeducation training can be recommended by clinicians since it provides more benefits.