• Biomedical Science Letters
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• v.16 no.2
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• pp.127-131
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• 2010

Mycobacterium leprae detection is difficult even with molecular biological techniques due to the low sensitivity of current methodologies. In this report, real-time PCR targeting the M. leprae-specific repetitive element (RLEP) sequence was developed as a new diagnostic tool and evaluated using clinical specimens. For this, M. leprae DNAs were extracted from skin biopsy specimens from 80 patients and analyzed by real-time PCR using TaqMan probe. Then, the detection efficiency of the real-time PCR was compared with that of standard PCR. In brief, the rate of positive detection by the standard PCR and real-time PCR was 32.50% and 66.25%, respectively. The results seemed to clearly show that the TaqMan real-time PCR developed in this study may be a useful tool for sensitive detection of M. leprae from clinical specimens.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2003.04a
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• pp.103-110
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• 2003

A hybrid structural reliability analysis method that integrates a commercial finite element program and a reliability analysis algorithm is proposed to estimate the safety of real structures in this paper. Since finite element method (FEM) is most commonly and widely used in the analysis and design practice of real structures, it appears to be necessary to use general FEM program in the structural reliability analysis. In this case, simple conventional reliability methods cannot be used because the limit state function can only be expressed in an algorithmic form. The response surface method(RSM)-based reliability algorithm with the first-order reliability method (FORM) found to be ideal in this respect and is used in this paper. The intention of use of RSM is to develop, albeit approximately, an explicit expression of the limit state function for real structures. The applicability of the proposed method to real structures is examined with help of the example in consideration of a concrete dam. Both the strength and serviceability limit states are considered in this example.

• Journal of applied mathematics & informatics
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• v.8 no.1
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• pp.71-80
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• 2001

The purpose of this paper is to give the classification of homogeneous integral table algebras of degree 5 containing a faithful real element of which 2. In fact, these algebras are classified to exact isomorphism, that is the sets of structure constants which arise from the given basis are completely determined. This is work towards classifying homogeneous integral table algebras of degree 5. AMS Mathematics Subject Classification : 20C05, 20C99.

• Transactions of the Korean Society of Automotive Engineers
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• v.3 no.5
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• pp.30-37
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• 1995

In this research a real time vehicle dynamic simulation software, to be used on real time vehicle simulators, is developed using relative coordinates and suspension super-element concept. Accuracy of the software is verified through comparisons of simulation results with those of a commercial mechanical system dynamic analysis package. It is demonstrated that real time simulation on a workstation with a 15 D.O.F. vehicle model is possible.

• Proceedings of the IEEK Conference
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• 2002.06d
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• pp.211-214
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• 2002

A novel structuring element for the morphological filter is proposed in order to detect a small target at a long distance. The modeling of the structuring element is based on the real data and implemented by parametric model approach. Several synthetic

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.397-402
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• 2003

Fracture resistance curves for concerned materials are required in order to perform elastic-plastic fracture mechanical analyses. Fracture resistance curve is built with J-integral values and crack extension values. The objective of this paper is to apply the load ratio method to the measurement of the crack length for the real scale pipe specimen. For these, the fracture test using the real scale pipe specimen and finite element analyses were performed. A 4-point bending jig was manufactured for the pipe test and the direct current potential drop method and the load ratio method was used to measure the crack extension and the length for the real scale pipe test. Finite element analyses about the compliance of the pipe specimen were executed for applying the load ratio method according to the crack length.

• Proceedings of the KSME Conference
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• 2004.04a
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• pp.557-562
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• 2004

For constructing virtual environment it is more natural to model object as deformable body than as rigid body. High accuracy of simulation of model and low-latency computational cost for real-time simulation should be guaranteed. We pre-compute Green function through finite element analysis of deformable body and it is possible to simulate deformation of body in real-time environment using Capacitance Matrix Algorithm. Also, the capacitance matrix algorithm enables to construct the haptic rendering which serves the reaction force through a haptic device. The Newmark scheme is used for the more realistic haptic rendering and dynamic simulation in real-time.

• Journal of the Earthquake Engineering Society of Korea
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• v.27 no.2
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• pp.77-82
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• 2023

The structural analysis module is an essential part of any integrated structural system. Diverse integrated systems today require, from the analysis module, efficient real-time responses to real-time input such as earthquake signals, extreme weather-related forces, and man-made accidents. An integrated system may also be for the entire life span of a civil structure conceived during the initial conception, developed throughout various design stages, effectively used in construction, and utilized during usage and maintenance. All these integrated systems' essential part is the structural analysis module, which must be automated and computationally efficient so that responses may be almost immediate. The finite element method is often used for structural analysis, and for automation, many effective finite element meshes must be automatically generated for a given analysis. A computationally efficient finite element mesh generation scheme based on the r-h method of mesh refinement using strain deviations from the values at the Gauss points as error estimates from the previous mesh is described. Shape factors are used to sort out overly distorted elements. A standard cantilever beam analyzed by four-node plane stress elements is used as an example to show the effectiveness of the automated algorithm for a time-domain dynamic analysis. Although recent developments in computer hardware and software have made many new applications in integrated structural systems possible, structural analysis still needs to be executed efficiently in real-time. The algorithm applies to diverse integrated systems, including nonlinear analyses and general dynamic problems in earthquake engineering.

• Journal of the Earthquake Engineering Society of Korea
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• v.15 no.5
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• pp.11-24
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• 2011

A real-time hybrid test of a 3 story-3 bay reinforced concrete frame which is divided into numerical and physical substructure models under uniaxial earthquake excitation was run using a fixed iteration implicit HHT time integration method. The first story inner non-ductile column was selected as the physical substructure model, and uniaxial earthquake excitation was applied to the numerical model until the specimen failed due to severe damage. A finite-element analysis program, Mercury, was newly developed and optimized for a real-time hybrid test. The drift ratio based on the top horizontal displacement of the physical substructure model was compared with the result of a numerical simulation by OpenSees and the result of a shaking table test. The experiment in this paper is one of the most complex real-time hybrid tests, and the description of the hardware, algorithm and models is presented in detail. If there is an improvement in the numerical model, the evaluation of the tangent stiffness matrix of the physical substructure model in the finite element analysis program and better software to reduce the computational time of the element state determination for the force-based beam-column element, then the comparison with the results of the real-time hybrid test and the shaking table test deserves to make a recommendation. In addition, for the goal of a "Numerical simulation of the complex structures under dynamic loading", the real time hybrid test has enough merit as an alternative to dynamic experiments of large and complex structures.

• Structural Engineering and Mechanics
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• v.52 no.6
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• pp.1099-1120
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• 2014

In this paper, reliability-based design optimization (RBDO) of structures is addressed. For this purpose, the global search and optimization capabilities of genetic algorithm (GA) are combined with the efficiency and reasonable accuracy of an advanced moment-based finite element reliability method. For performing RBDO, three variants of GA including a real-coded, a binary-coded and an improved binary-coded GA are developed. In these methods, GA performs (finite element) reliability analyses to evaluate reliability constraints. For truss structures which include finite element modeling, reliability constraints are evaluated using finite element reliability analysis. Response sensitivity required for finite element reliability analysis is obtained by direct differentiation method (DDM) rather than finite difference method (FDM). The proposed methods are examined within four standard test examples and real-world design problems. The results illustrate the superiority and efficiency of the improved binary-coded GA. Results also illustrate that DDM significantly reduces the computational cost and improves the efficiency of the optimization procedure.