• 대한의생명과학회지
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• 제16권2호
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• pp.127-131
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• 2010

Mycobacterium leprae detection is difficult even with molecular biological techniques due to the low sensitivity of current methodologies. In this report, real-time PCR targeting the M. leprae-specific repetitive element (RLEP) sequence was developed as a new diagnostic tool and evaluated using clinical specimens. For this, M. leprae DNAs were extracted from skin biopsy specimens from 80 patients and analyzed by real-time PCR using TaqMan probe. Then, the detection efficiency of the real-time PCR was compared with that of standard PCR. In brief, the rate of positive detection by the standard PCR and real-time PCR was 32.50% and 66.25%, respectively. The results seemed to clearly show that the TaqMan real-time PCR developed in this study may be a useful tool for sensitive detection of M. leprae from clinical specimens.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 2003년도 봄 학술발표회 논문집
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• pp.103-110
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• 2003

A hybrid structural reliability analysis method that integrates a commercial finite element program and a reliability analysis algorithm is proposed to estimate the safety of real structures in this paper. Since finite element method (FEM) is most commonly and widely used in the analysis and design practice of real structures, it appears to be necessary to use general FEM program in the structural reliability analysis. In this case, simple conventional reliability methods cannot be used because the limit state function can only be expressed in an algorithmic form. The response surface method(RSM)-based reliability algorithm with the first-order reliability method (FORM) found to be ideal in this respect and is used in this paper. The intention of use of RSM is to develop, albeit approximately, an explicit expression of the limit state function for real structures. The applicability of the proposed method to real structures is examined with help of the example in consideration of a concrete dam. Both the strength and serviceability limit states are considered in this example.

• Journal of applied mathematics & informatics
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• 제8권1호
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• pp.71-80
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• 2001

The purpose of this paper is to give the classification of homogeneous integral table algebras of degree 5 containing a faithful real element of which 2. In fact, these algebras are classified to exact isomorphism, that is the sets of structure constants which arise from the given basis are completely determined. This is work towards classifying homogeneous integral table algebras of degree 5. AMS Mathematics Subject Classification : 20C05, 20C99.

• 한국자동차공학회논문집
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• 제3권5호
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• pp.30-37
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• 1995

In this research a real time vehicle dynamic simulation software, to be used on real time vehicle simulators, is developed using relative coordinates and suspension super-element concept. Accuracy of the software is verified through comparisons of simulation results with those of a commercial mechanical system dynamic analysis package. It is demonstrated that real time simulation on a workstation with a 15 D.O.F. vehicle model is possible.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2002년도 하계종합학술대회 논문집(4)
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• pp.211-214
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• 2002

A novel structuring element for the morphological filter is proposed in order to detect a small target at a long distance. The modeling of the structuring element is based on the real data and implemented by parametric model approach. Several synthetic

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.397-402
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• 2003

Fracture resistance curves for concerned materials are required in order to perform elastic-plastic fracture mechanical analyses. Fracture resistance curve is built with J-integral values and crack extension values. The objective of this paper is to apply the load ratio method to the measurement of the crack length for the real scale pipe specimen. For these, the fracture test using the real scale pipe specimen and finite element analyses were performed. A 4-point bending jig was manufactured for the pipe test and the direct current potential drop method and the load ratio method was used to measure the crack extension and the length for the real scale pipe test. Finite element analyses about the compliance of the pipe specimen were executed for applying the load ratio method according to the crack length.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2004년도 춘계학술대회
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• pp.557-562
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• 2004

For constructing virtual environment it is more natural to model object as deformable body than as rigid body. High accuracy of simulation of model and low-latency computational cost for real-time simulation should be guaranteed. We pre-compute Green function through finite element analysis of deformable body and it is possible to simulate deformation of body in real-time environment using Capacitance Matrix Algorithm. Also, the capacitance matrix algorithm enables to construct the haptic rendering which serves the reaction force through a haptic device. The Newmark scheme is used for the more realistic haptic rendering and dynamic simulation in real-time.

• 한국지진공학회논문집
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• 제27권2호
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• pp.77-82
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• 2023

The structural analysis module is an essential part of any integrated structural system. Diverse integrated systems today require, from the analysis module, efficient real-time responses to real-time input such as earthquake signals, extreme weather-related forces, and man-made accidents. An integrated system may also be for the entire life span of a civil structure conceived during the initial conception, developed throughout various design stages, effectively used in construction, and utilized during usage and maintenance. All these integrated systems' essential part is the structural analysis module, which must be automated and computationally efficient so that responses may be almost immediate. The finite element method is often used for structural analysis, and for automation, many effective finite element meshes must be automatically generated for a given analysis. A computationally efficient finite element mesh generation scheme based on the r-h method of mesh refinement using strain deviations from the values at the Gauss points as error estimates from the previous mesh is described. Shape factors are used to sort out overly distorted elements. A standard cantilever beam analyzed by four-node plane stress elements is used as an example to show the effectiveness of the automated algorithm for a time-domain dynamic analysis. Although recent developments in computer hardware and software have made many new applications in integrated structural systems possible, structural analysis still needs to be executed efficiently in real-time. The algorithm applies to diverse integrated systems, including nonlinear analyses and general dynamic problems in earthquake engineering.

• 한국지진공학회논문집
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• 제15권5호
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• pp.11-24
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• 2011

고정반복법에 의한 암시적 HHT 시간적분법을 이용하여 3층 3경간 철근콘크리트 골조구조물을 수치해석모형과 물리적 분구조모형으로 나누어 실시간 하이브리드실험을 실시하였다. 물리적 부분구조모형으로는 1층 내부 비연성기둥 1개소가 선택되었고, 수치해석모형에 일축 방향의 지진하중을 시편이 심한 손상에 의하여 파괴에 이를 때까지 작용시켰다. 비선형 유한요소해석 프로그램인 Mercury가 실시간 하이브리드실험을 위하여 새로이 개발 및 적용되었다. 실험결과는 물리적 부분구조모형의 상부 수평방향 층간변위비를 OpenSees에 의한 수치해석시뮬레이션과 진동대실험의 그것과 비교하였다. 본 실험은 가장 복잡한 실시간 하이브리드실험 중의 하나이고, 하드웨어, 알고리즘 그리고 모형에 대한 기술적인 내용을 본 논문에 자세히 설명하였다. 수치해석모형의 개선, 물리적 부분구조 모형 접선강성행렬의 유한요소해석 프로그램에서의 평가 그리고 하중기반 보-요소의 요소상태결정의 연산시간을 줄이기 위한 소프트웨어의 개선이 이루어진다면 실시간 하이브리드실험과 진동대실험결과의 비교는 권장할 만하다. 그리고 "지진과 같은 동적하중하의 복잡한 구조물의 수치해석시뮬레이션"이라는 목적을 위하여 실시간 하이브리드실험은 동적하중에 대한 실험적 검증을 점진적으로 수치해석모형으로 대체하기 위한 저비용-고효율 실험법으로서의 가치를 충분히 가지고 있다고 할 수 있다.

• Structural Engineering and Mechanics
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• 제52권6호
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• pp.1099-1120
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• 2014

In this paper, reliability-based design optimization (RBDO) of structures is addressed. For this purpose, the global search and optimization capabilities of genetic algorithm (GA) are combined with the efficiency and reasonable accuracy of an advanced moment-based finite element reliability method. For performing RBDO, three variants of GA including a real-coded, a binary-coded and an improved binary-coded GA are developed. In these methods, GA performs (finite element) reliability analyses to evaluate reliability constraints. For truss structures which include finite element modeling, reliability constraints are evaluated using finite element reliability analysis. Response sensitivity required for finite element reliability analysis is obtained by direct differentiation method (DDM) rather than finite difference method (FDM). The proposed methods are examined within four standard test examples and real-world design problems. The results illustrate the superiority and efficiency of the improved binary-coded GA. Results also illustrate that DDM significantly reduces the computational cost and improves the efficiency of the optimization procedure.