• Journal of information and communication convergence engineering
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• v.15 no.4
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• pp.227-231
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• 2017

Recently, as the number of safety accidents caused by reagents increases, researches on a system that can reduce safety accidents are underway. Existing systems managed reagent cabinet through various sensors. On the other hand, there are disadvantages in that countermeasures against simultaneous danger situations are insufficient at multi-reagents cabinet. In order to solve this problem, this paper proposes a system to manage the reagents cabinet through danger priority. Danger priorities are selected through domestic chemical accident cases and the Chemical Safety Management Act. If a danger situation occurs in the reagent cabinet, make sure it is from a single or multiple reagent cabinets. For multiple reagent cabinets, compare the reagent cabinet priorities and run the device sequentially from the reagent cabinet with the highest priority. Thus, by operating the device according to the danger priority, the chain reaction can be prevented in advance and the reagent cabinet can be safely managed.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.790-791
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• 2016

The system used in the laboratory of chemistry and medical is management only by measuring the temperature inside the reagent management within and recording in handwriting. When you hold the reagent, it can not recognize in real time the problems that occur in the interior, an accident occurs. you can not find a use record reagent storage, a problem with the management of an efficient reagent can be generated. In this paper, we propose a reagent management system that leverages the embedded boards and sensors in the laboratory reagents effectively manage to resolve it. As a result, Converting the information of the reagent to the data using the NFC, the administrator can identify the reagent user to register and manage hazardous reagents. Converted by using the NFC information of the reagent to the data, the administrator can identify the reagent user to register and manage hazardous reagents, temperature, humidity, so that it can be controlled by utilizing the VOC sensor to. Also it is passes the message to the administrator in the event of a particular risk situation. This is believed to enable the effective administration in a laboratory reagent.

• Archives of Pharmacal Research
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• v.11 no.2
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• pp.134-138
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• 1988

Urine measurements by MNR were made for 25 persons including cancer and non-cancer patients. The aromatic proton signals of NMR wer observed much more often in cancer patients' urine than non-cancer patients' one. To compare the amount of the phenolic compounds excreted in urine between cancer and non-cancer patient, urine analysis by HPLC with UV detector was performed. Total peak area and major peak areas of cancer patients' urine wer emuch greater than those of non-cancer patients' one. To check the phenolic compound excreted in urine, a new jellied reagent named Gift reagent which was based on Millon's reagent, was developed for urine color reaction. When the reagent was tested, the sensitivity and specificity for urine samples of 69 persons including cancer and non-cancer patients were measured by 85.3% and 91.4%, respectively, indicating that the Gift reagent afford a possibility of cancer diagnosis.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.579-580
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• 2017

Recently, as safety accidents by reagents increase in laboratories, systems are being developed to safely manage reagents. The existing system monitoring and manages the reagent through the web page, but the internal environment change of the reagent cabinet is considered or the remote monitoring and control function is insufficient. In order to solve this problem, this paper predicts the deterioration of the reagent loaded in the reagent cabinet. And we propose a system that can monitoring and control remotely. It predicts the deterioration of the reagent through the temperature attached to the inside of the reagent cabinet, the value measured by the humidity sensor and the validity period of the reagent, and sends a alert message to the manager. The manager monitoring and controls the reagent cabinet through the application. By predicting the deterioration of the reagents and remotely managing the reagents cabinet it is thought that safety accidents can be reduced.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.23 no.6
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• pp.652-658
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• 2019

When IoT is applied to various research experiment fields such as physics, pharmacy, biology and medicine, it can increase the safety and convenience of researchers by intelligently monitoring and controlling research equipment and environment with various sensors and devices. For accurate and convenient record management and the research history and the basis but also for the reverse tracking, real-time reagent measurement and registration should be provided as a research support automation services. Currently, existing methods of reagent management are operated by computerized method, but reagent registration and management are not automated. And also record is managed manually, there are many hassles and problems such as a record error and too much time required for quantification and registration for many reagents. In this paper, we study a real time reagent measuring and registration method based on IoT to resolve the problems aforementioned, by the information of the reagent acquired by image recognition and NFC method.

• YAKHAK HOEJI
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• v.35 no.4
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• pp.288-294
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• 1991

A new fluorescent derivatizing reagent was developed to be used in HPLC for the trace determination of primary and secondary amines. This new reagent, 1-(N,N-dimethylamino)pyrene-6-sulfonyl chloride, was synthesized by the chlorination of sodium 1-(N,N-dimethylamino)pyrene-6-sulfonate which was obtained from 1-(N,N-dimethylamino)pyrene after sulfonation. Ephedrine and norephedrine were derivatized quantitatively by this reagent. The optimum conditions for the derivatization such as pH, reagent concentration, reaction time and reaction temperature ware examined. The structures of derivatives were identified by IR, $^{1}$H-NMR and MS methods. The fluorescence properties and the stability of the derivatives were examined. The derivatives were separated on silica column with an isocratic elution using the mixture of n-hexane and ethylacetate and monitored by fluorescene detector. Linear calibration curves were obtained and detection limits in a 10 $\mu$l injection volume were 5 picomole for ephedrine and norephedrine.

• Bulletin of the Korean Chemical Society
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• v.8 no.4
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• pp.313-318
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• 1987

The approximate rate and stoichiometry of the reaction of excess Thexylbromoborane-methyl sulfide, $ThxBHBr{\cdot}SMe_2,$ with selected organic compounds containing representative functional groups under standardized conditions (methylene chloride, $0^{\circ}C)$ were studied in order to characterize the reducing characteristics of the reagent for selective reductions. The selectivity of the reagent was also compared to the selectivity of thexylchloroborane-methyl sulfide. Thexylbromoborane appears to be a much milder and hence more selective reducing agent than thexylchloroborane. The reagent tolerates many organic functionalities. Thus, the reagent shows very little reactivity or no reactivity toward acid chlorides, esters, epoxides, amides, nitro compounds including simple olefins. However, this reagent can reduce aldehydes, ketones, carboxylic acids, nitriles, and sulfoxides. Especially the reagent reduces carboxylic acids including ${\alpha},{\beta}$ -unsaturated ones and nitriles to the corresponding aldehydes. In addition to that, thexylbromoborane shows good stereoselectivity toward cyclic ketones, much better than the chloro-derivative.

• Analytical Science and Technology
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• v.36 no.1
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• pp.1-11
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• 2023

A new, sensitive, and reliable flow injection methodology was investigated for the determination of lead ion (II) in vegetables' samples using a laboratory-prepared reagent 2-[(6-methoxy-2-benzothiazoly)azo]-4-methoxy phenol (6-MBTAMP). Infrared spectroscopy, UV-visible spectrophotometry, Energy dispersive X-ray spectroscopy (EDX), Elemental Analysis (CHN), nuclear magnetic resonance spectroscopy ¹HNMR, and ¹³CNMR techniques were used to characterize the reagent and lead (II) complex. The method is based on lead ion (II) reacting with the reagent (6-MBTAMP) in a neutral solution to produce a green-red complex with a maximum absorbance at 670 nm. The optimum conditions, such as flow rate, lead ion (II) volume, reagent volume, medium pH, reagent concentration, and reaction coil length were thoroughly examined. The limits of detection (LOD) and quantification (LOQ) were determined to be 0.621 mg·L^-1 and 2.069 mg·L^-1 , respectively, while Sandell's sensitivity was determined to be 0.345 ㎍·cm^-2.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2016.10a
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• pp.798-799
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• 2016

Reagent Cabinet of existing that management does not classify the reagents by characteristics it has a problem that can result dangerous situations. Also, the situation impossible the ability to control the reagent cabinet from outside in the event of dangerous situations. In this paper, design a system for managing reagents it can be classified according to the characteristics and the reagent cabinet management on a mobile device. Utilizing the characteristics classification from first to sixth classification management to fit the classification of each reagent. The mobile device transmits the sensor control, reagent and sensor data monitoring, dangerous situation occurs when the alarm message. Accordingly, it is expected through the characteristics classification reduce accidents in the laboratory if the dangerous situation will be a prompt action from the outside.

• The Korean Journal of Nuclear Medicine Technology
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• v.28 no.1
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• pp.81-87
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• 2024

Purpose: CA 19-9 is the most widely used tumor marker for the diagnosis of digestive system tumor, especially pancreatic and biliary tract cancer. This study was conducted to improve the result value near reference range by comparing the reagents of CA 19-9 one step method and two step method. In addition, it was intended to establish a standard for selecting reagents. Material and Methods: 120 patients who visited the National Cancer Center in 2023 were selected as subjects for this study. The reagents used in the study were CA 19-9 IRMA kits (Shinjin, Korea) and three types of reagents were compared. Two step method reagent that is currently being used (A), one step method reagent (B) and two step method reagent improved by request (C) were compared and regression analysis was performed on their data. And we also performed recovery test, linearity test and hook effect test for each reagent. Result: There were 46 cases of reagent B in which the concentration value was lower than the result measured in reagent A that was previously used, and 77 cases of reagent C. As a result of regression analysis of reagents A, B, and C, the coefficients of determination of reagents A and B, reagents A and C, and reagents B and C were 0.653, 0.577, and 0.875. In the recovery rate test and the linearity test, the results of all reagents were good, and in the hook effect test, reagent B showed a hook effect at a low value. Conclusion: The improved reagent C appears to have been improved based on the concentration value of reagent B, which the manufacturer judged to be more stable at low concentrations. The hook effect in reagent B can be a fatal reason for disqualification when selecting reagents in general patient samples which high-concentration samples appear frequently. The first improved reagent C will be able to be used once it is confirmed that it has more stability for various concentration values.