• 한국전문물리치료학회지
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• 제29권2호
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• pp.147-155
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• 2022

Background: Although various conventional approaches have been employed to reduce spasticity in neurological rehabilitation, only a few studies have shown scientific evidence for its effectiveness. Thus, we introduced a different concept (Ueda method) of rehabilitation therapy that can complement the limitations of conventional therapy. Objects: This study aimed to investigate the immediate effects of the application of the Ueda method on patients with spasticity after stroke via an electrophysiological study. Methods: We conducted a randomized double-blind pilot study in two rehabilitation hospitals involving 30 stroke patients who were randomly allocated to the Ueda (n = 15) and convention (n = 15) groups. Electromyographic data of six examined muscles in both upper extremities of all patients were recorded. The A-ApA index and activation ratios of upper extremity muscles were evaluated and compared between the groups to confirm post-intervention changes in upper-extremity flexor spasticity and flexion synergies. Repeated-measures analysis of variance was conducted to confirm the therapeutic effect (2 × 2) as a function of group (Ueda vs. convention) and time (pre-/post-intervention) on all outcome measures (p < 0.05). Results: In the Ueda group, the mean A-ApA index values differed significantly before and after the intervention (p = 0.041), indicating a weak evidence level; however, the effect size was medium (d = -0.503). The interaction effects of the A-ApA index between the Ueda and convention groups and between pre-intervention and post-intervention stages were significant (p = 0.012). The effect size was large (n_p² = 0.220). In the Ueda group, the activation ratios of the anterior deltoid fiber significantly decreased after the intervention in all reaching tasks. Conclusion: The Ueda method reduces upper-extremity flexor spasticity and changes its synergy in stroke patients and should be considered a rehabilitation therapy for spastic stroke patients.

• 디자인융복합연구
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• 제17권4호
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• pp.17-29
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• 2018

완전 자율주행 단계에 이르기 전까지 부분 자율주행 차량에서는 시스템이 특정 상황에서 운전자에게 직접 운전을 하도록 요청하는 제어권 전환 요청(TOR)이 필수적이다. 이 연구의 목적은 인간-자동차 인터랙션 방식 중 HDD(Head-Down Display)보다 HUD(Head-Up Display)가 제어권 전환 요청 시 사용자 경험 인식에서 더 유리한지 비교하는 것이다. 운전 시뮬레이터 실험을 통해 참가자가 자율주행 상황에서 부가적 과업인 게임을 하다가 제어권 전환 요청을 인지하면 직접 운전을 수행하도록 하였다. 실험 결과, 반응시간과 주관적 작업 부하에서는 차이가 없었으나, '사용 용이성'과 '만족도'에서 HUD 방식이 HDD보다 더 우수한 것으로 나타났다. 자율 주행시 HUD를 통해 부가적 과업을 하도록 디자인하는 것이 제어권 전환 요청 기능의 사용자 경험을 개선하는 효과가 있었다. 이 연구는 자율주행 맥락에서의 사용자 경험 디자인 가이드라인 설정을 위한 실증 사례를 제시했다는 점에서 의의가 있다.

• 대한토목학회논문집
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• 제28권1D호
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• pp.21-27
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• 2008

서울도심의 경제는 날로 악화되고 있고, 활성화시킬 대안이 필요한 실정이다. 그 대안으로 본 연구에서는 워나비.쇼나비 정보시스템을 개발한다. 쇼나비시스템은 보행자들이 쇼핑할 때 상점의 이름, 위치, 주력상품 및 가격 등에 대한 정보를 실시간으로 제공하는 것을 목적으로 한다. 한편, 워나비시스템은 차량네비게이터와 유사한 기능을 보행자를 위해 수행하는 시스템으로 보행으로 쇼핑하는 사람들에게 길안내의 역할을 하게 된다. 이 시스템을 이용하게 되면 보행자들은 가장 빠른길, 편안한 길, 즐거운 길 등 다양한 보행경로정보를 이동 중 제공 받게 되고 동시에 대중교통정보도 제공받을 수 있다. 워나비.쇼나비 시스템을 실제 작동시키기 위해 필요한 정보통신기술로는 GPS와 RFID 기술을 복합한 방식을 제시했다. 이 시스템을 통해 보행을 활용한 쇼핑이 활성화되고 활기찬 도심으로 거듭날 것을 확신한다.

• 전기전자학회논문지
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• 제28권2호
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• pp.174-179
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• 2024

본 논문에서는 극저온 냉동기를 사용하여 양자 컴퓨터 제어 및 read-out을 위한 CMOS 기반의 집적회로 측정 셋업을 제시한다. CMOS 회로는 큐비트 안정성과 잡음 감소를 위해 3~5 K의 극저온에서 작동해야한다. 기존의 극저온 측정 시스템은 액체 헬륨 담금질이며, 이는 소모성 자원을 장기간 사용하기에 비용이 많이 소모된다. 따라서 헬륨 가스를 장기간 사용해도 비용이 들지 않는 폐쇄 사이클 냉동기(Closed Cycle Refrigerator, CCR) 기반의 극저온 측정 시스템에 대해 설명한다. Gifford-Mcmahon(G-M) 방식의 극저온 냉각기를 이용하여 4.7 K에 도달할 수 있는 냉동기를 구축하였다. 이는 가격 경쟁력이 우수한 극저온 냉동기 셋업이 될 것으로 기대된다.

• 한국해양생명과학회지
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• 제9권1호
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• pp.47-52
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• 2024

Light is a major external environmental factor that influences the circadian rhythm of photosynthetic organisms and various physiological phenomena, such as growth, maturation, and behavior. The number of light-reaching organisms changes depending on the season and atmospheric conditions, and the intensity and wavelength of light differ depending on the organisms inhabiting the environment. Altered light changes the circadian rhythm of fish, which is controlled by clock genes, such as period 2 (Per2), cryptochrome 1 (Cry1), and melatonin. In this study, we set the zeitgeber time (ZT; 14 light-10 dark, LD) based on the actual sunrise and sunset times and examined Per2 and Cry1 activities, levels of aralkylamine N-acetyltransferase (AANAT), and melatonin in Pholis nebulosa, a drifting seaweed species exposed to irregular light. Per2 and Cry1 levels increased during the daytime and decreased after sunset. The AANAT levels decreased during the daytime and increased during the night. Melatonin concentration was highest around midnight (ZT21, 23:30), but exhibited similar concentrations during the daytime. While the activity of Per2, Cry1, and AANAT levels exhibited a typical circadian rhythm observed in most vertebrates, melatonin concentrations did not show a significant difference between the daytime and nighttime. These findings provide insights into the circadian rhythm patterns of organisms exposed to irregular light environments, such as P. nebulosa, which differ from those of typical fish species.

• 상하수도학회지
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• 제37권5호
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• pp.271-279
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• 2023

Fouling is an inevitable problem in membrane water treatment plant. It can be measured by trans-membrane pressure (TMP) in the constant flux operation, and chemical cleaning is carried out when TMP reaches a critical value. An early fouilng alarm is defined as warning the critical TMP value appearance in advance. The alarming method was developed using one of machine learning algorithms, decision tree, and applied to a ceramic microfiltration (MF) pilot plant. First, the decision tree model that classifies the normal/abnormal state of the filtration cycle of the ceramic MF pilot plant was developed and it was then used to make the early fouling alarm method. The accuracy of the classification model was up to 96.2% and the time for the early warning was when abnormal cycles occurred three times in a row. The early fouling alram can expect reaching a limit TMP in advance (e.g., 15-174 hours). By adopting TMP increasing rate and backwash efficiency as machine learning variables, the model accuracy and the reliability of the early fouling alarm method were increased, respectively.

• 한국간담췌외과학회지
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• 제26권3호
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• pp.211-219
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• 2022

Backgrounds/Aims: Historically, incidence and survival analysis and annual traits for primary liver cancer (LC) has not been investigated in a population-based study in Korea. The purpose of the current study is to determine incidence, survival rate of patients with primary LC in Korea. Methods: We conducted a retrospective cohort study using Korea Central Cancer Registry based on the Korea National Cancer Incidence Database. Statistical analysis including crude rate and age-standadized rate (ASR) of incidence and mortality was performed for LC patients registered with C22 code in International Classification of Diseases, tenth revision from 1999 to 2019. Subgroup analysis was performed for hepatocellular carcinoma (HCC, C22.0) and intrahepatic cholangiocarcinoma (IHCC, C22.1). Results: The crude incidence rate of HCC (21.0 to 22.8 per 100,000) and IHCC (2.3 to 5.6 per 100,000) increased in the observed period from 1999 to 2019. The ASR decreased in HCC (20.7 to 11.9 per 100,000) but remained unchanged in IHCC (2.4 to 2.7 per 100,000). The proportion of HCC patients diagnosed in early stages (localized or regional Surveillance, Epidemiology, and End Results or SEER stage) increased significantly over time. As expected, 5-yeat survival rate of HCC was greatly improved, reaching 42.4% in the period between 2013 and 2019. This trait was more prominent in localized SEER stage. On the other hand, the proportion of IHCC patients diagnosed in localized stage remained unchanged (22.9% between 2013 and 2019), although ASR and 5-year survival rate showed minor improvements. Conclusions: A great improvement in survival rate was observed in patients with newly diagnosed HCCs. It was estimated to be due to an increase in early detection rate. On the contrary, detection rate of an early IHCC was stagnant with a minor improvement in prognosis.

• 동아시아식생활학회지
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• 제17권4호
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• pp.571-579
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• 2007

The aim of this study was to predict the development process of the Korean food service industry by forecasting the per capita GDP. Forecasting the GDP, involved two primary approaches. One was related to looking at the Korean food service industry's situation by per capita GDP and comparing it to that of the US and Japan. The other was to predict food service industry projections in Korea by quantitative forecasting models. Holt's simple exponential smoothing method and new types of the series models(Damped trend exponential smoothing method), were employed to predict the per capita GDP. The accuracy of the models was measured by MAPE. The empirical results of the forecasting models indicate that the three time series models performed fairly well. Of these Damped trend Damped trend exponential smoothing performed best with the lowest MAPE(9.9%). The results show that the time for reaching a per capita GDP level of $20,000 was 2008 with the Damped trend model and 2009 with the Holt model. Moreover, we found that a per capita GDP level of $30,000 will be achieved in 2012 from the Damped trend model and in 2013 from the Holt model. Within this study, the implications for the Korean food service industry are further discussed. It was predicted there will be a stabilization period in 2008 or 2009 in Korea with achievement of a per capita GDP of $20,000. At this time, major food service industry companies will need to invest in equipment toy external growth and there will be industry trends toward ethnic food and theme restaurants. Also, if a per capita GDP of $30,000 is achieved by 2012 or 2013, the Korean food industry will need to be highly responsive. Therefore, food industry companies should forecast and study customer values and prepare for changes.

• 한국수산과학회지
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• 제2권1호
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• pp.87-91
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• 1969

보리새우의 대량종묘생산을 목적으로 대형콘크리이트수조 A ($3.4\times1.9\times1.0m$)와 2개의 소형콘크리이트수조 B와 C($1.45\times0.85\times1.0$)를 이용하여 유생사육실험을 하였다. 1) 산난후 제1기 조이야까지의 발생기간은 사육수조에 차이없이 수온 $23^{\circ}C$ 내외에서 1.5-2일이 소요되었다. 그러나 조이야기 이후 차이가 생겨 Post-larva까지의 변태기간은 수조A에서는 산난후 19-20일, 수조B에서는 15-16일, 수조C에서는 16-17일이 각기 소요되었다. 2) 유생의 체장은 3개의 수조간에 차이가 없었다. 3) Post-larva는 산난후 36-40일경에 치하로 되었다. 4) 유생 사망률은 전유생 기간중 제1기조이야에서 제2기조이야로 변태하는 기간에 가장 높아서 수조A가$51.39\%$ 수조B가 $50.70\%$, 수조 C는 $31.90\%$를 나타내었으며 마이시스기이후는 비교적 안정된 상태를 나타내었다. 5) 노우플리우스기로부터Post-larva까지 기간의 유생 총사망률은 각수조 비슷하게 $75\%$ 내외를 나타내어 전체적으로 약 $25-30\%$의 종묘를 생산할 수 있었다.

• 대한임상독성학회지
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• 제9권2호
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• pp.61-70
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• 2011

Purpose: This study investigated the effect on survival rate for organophosphate intoxication patients who received trachostomy. This research was conducted to help identify appropriate treatment of patients who received a trachostomy. Methods: This research was retrospectively conducted using the medical records of 141 patients who arrived at the Chosun University Hospital emergency medical center between Jan 2007 and Dec 2010, suffering from organophosphate intoxication. They were placed in two groups including one which received trachostomy as part of their treatment and one that did not. The effect of each variable on mortality was evaluated by regressionanalysis. Results: Of 141 patients with organophosphate intoxication, 105 of them did not tracheostomy and 16 were dead cohorts (15.2%). Their size of pupil was 1mm. Factors such as amount of organophosphate ingested, PAM time after ingestion, average body temperature, arrival time, atropinization time after ingestion, AST/ALT, Bun/Cr all appeared to be significant factors in death cohorts (P<0.05). 36 patients among the total had tracheostomy and 11 ones of them were in dead cohort (30.6%) and their average age was 58 years. The facts affect the state of patients in dead cohort include the amount of intoxication which between $327.27{\pm}194.1ml$, performing intubation 686 mins after intubation, reaching to the hospital after 580mins, injecting PAM 744 mins after intoxication, injecting atropine 627 mins after intoxication. The largest cases of patient's state was found to be stupor with 14 patients (38.9%) the level of Cholinesterase in blood appeared to be significant in dead cohort as $391.00{\pm}353.9IU/L$ (P<0.05). Conclusion: Further planned studies are necessary on the use of tracheostomy for treatment of poisoning victims, especially those intoxicated by organophosphorus insecticides.