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An Open-Label Study of the Improvements in Clinical Symptoms and Neurocognitive Functions in Korean Children and Adolescents with Attention-Deficit Hyperactivity Disorder after Treatment with Metadate CD (국내 주의력결핍 과잉행동장애 아동 및 청소년에서 메타데이트CD의 임상증상 및 신경인지기능 개선 효과에 대한 개방 연구)

  • Yoo, Han-Ik K.;Kim, Bong-Seog;Joung, Yoo-Sook;Bahn, Geon-Ho;Song, Dong-Ho;Ahn, Dong-Hyun;Lee, Young-Sik
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.22 no.4
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    • pp.253-261
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    • 2011
  • Objectives : This study aimed to investigate the efficacy and safety of Metadate CD (MCD) when given to Korean children and adolescents with attention-deficit hyperactivity disorder (ADHD). We also explored the effects of the drug on diverse neuro-cognitive functions. Methods : Ninety-one subjects with ADHD (mean age 8.6${\pm}$2.2 years) were recruited at 6 outpatient clinics in Seoul, Korea. We used the ADHD Rating Scale (ARS), Clinical Global Impression (CGI), and comprehensive attention test (CAT) to measure the drug's effects. Results : After 0.92${\pm}$0.32mg/kg/day of MCD were administered for 57.4${\pm}$7.6 days, there was a 48.5% reduction in the mean total ARS scores (p<.001). Fifty-seven subjects (64.8%) showed either much improved or very much improved outcomes on the CGI-Improvement scale. The CGI-Severity scale also decreased from an average of 4.7 to an average of 2.9 (p<.001). Errors and response time standard deviations of the CAT, sustained attention test-to-response tasks, the flanker test, and divided attention test scores decreased after treatment (p<.05). The forward memory span of the spatial working memory test scores increased (p<.05). Thirty-five patients (39.8%) experienced side effects, of which the most common were headache (14.8%), nausea (12.5%), and anorexia (9.1%). Conclusion : This open-label study suggests that MCD is effective and safe in improving the symptoms and neurocognitive functions of Korean children and adolescents with ADHD.

The Review of Optimum Level of SDR in Empirical Soil Erosion Model (경험적 토사유실모형에서 SDR의 적정성 검토)

  • Lee, Geun-Sang;Park, Jin-Hyeog;Lee, Eul-Rae;Hwang, Eui-Ho;Chae, Hyo-Sok
    • Proceedings of the Korea Water Resources Association Conference
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    • 2010.05a
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    • pp.774-778
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    • 2010
  • Upland erosion pollutes surface waters and often causes serious problems when deposition occurs. This study builds a sediment rating curve using the measured sediment yield and the simulated soil erosion by a GIS-embedded empirical model. The coefficient of determination ($R^2$) between the simulated soil erosion and the measurement sediment yields with rainfall amount are 0.427 for Donghyang and 0.667 for Cheonchen, but the values with rainfall intensity are 0.873 and 0.927 respectively. The data are divided into two groups: one for calibration during 2002-2005 (48 months) and the other for estimation during 2006-2008 (36 months). The first data group (2002-2005) was used to derive the SDR with an aid of soil erosion calculated by the USLE and the measured sediment yield. The mean SDR with rainfall amount is 6.273 and 3.353, respectively, while 4.799 and 2.874 for rainfall intensity. But the standard deviation (STD) with rainfall intensity is 0.930 and 0.407, which is much less than that with rainfall amount (3.746 and 2.090) for both sites. The results show the derived SDR provides reasonable accuracy and rainfall intensity gives better performance in calculating soil erosion than rainfall amount.

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The Home Care Need and the Burden of a Primary Family Care Giver with Senile Dementia Patients (치매노인을 돌보는 가족원의 부양부담감과 가정간호요구도)

  • Son, Young-Ju;Kang, Ki-Seon;Kim, Soo-Jjn
    • Research in Community and Public Health Nursing
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    • v.11 no.2
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    • pp.423-440
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    • 2000
  • This research was conducted to identify the following: the home care needs of patients with dementia and the burden on the primary family care giver: to provide basic data required to develop nursing intervention for the care giver: and to suggest recommendations for medical institutions and social services that could reduce the burden on the families of people suffering from dementia. subjects of this research were 53 patients of the two Public Health Centers of Cheju Province who are suffering from dementia and their families. The instrument used in the research was Kuen. Jung Don (1994)' s assessment tool of burden in the primary family care giver who has parents with senile dementia and Yoo. Young Mi(1998)'s assessment tool of home care need. modified by the researcher in the questionnaire by a Likert rating scale. The period of data collection was from February 8. 2000 to March 10. 2000. Collected data was analyzed by SPSS, using mean, standard deviation. ANOVA, t-test and Pearson correlation coefficient. The result of this research was that there was not a significant correlation between the burden on the care giver and the level of dementia, its duration, the patient's ability to perform daily tasks, the period of care giving. and the use of social services, although the lower the patient's ability to perform daily tasks. and the worse the care giver's own health situation, the higher the burden on the primary family care giver. The following suggestions are made based on the results of this research. 1. More than half of the subjects don't use social facilities and services. More publicity and referral efforts are needed about medical institutions. nursing institutions and other facilities that specialize in services for dementia sufferers and their families. 2. Nursing services should include intensive education for the primary care giver in the most important aspects of home care. 3. Further research should be done, and should include data from all parts of Cheju Province.

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Effects of the Application of Lower Extremities Exercise and Elastic Compression Stockings on Edema and Pain of Lower Extremities in Nurses (하지운동과 탄력압력스타킹 적용이 일종합병원 간호사의 하지부종과 하지통증에 미치는 영향)

  • Choi, Young-Soon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.11
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    • pp.8037-8045
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    • 2015
  • The purpose of this study was to identify the effects of the application of elastic compression stockings and lower extremities exercise on edema and pain of lower extremities in hospital nurses. The participants were 30 hospital nurses working at a general hospital. The participants were categorized into three groups such as, 10 for an experimental group of the application of the elastic compression stocking, 10 for another experimental group of the application of Lower extremities exercise and 10 for a control group. Edema of the lower extremities were measured in terms of the girths of ankles and calves. And pain of the lower extremities were measured in terms of the score by NRS(Numerical Rating Scale). The data were analyzed with Frequency, Percentage, Mean, Standard Deviation, ${\chi}^2$-test and ANOVA to identify the participants' characteristics, SPSS Win 21.0 program was used for analysing. There are significant differences in lower extremity edema among the experimental group of lower extremities exercise, experimental group of elastic compression stocking and control group was supported(Rt Calf F=0.645, p=.000, Lt Calf F=21.941, p=.000). There are significant differences in lower extremity pain the experimental group of lower extremities exercise, experimental group of elastic compression stocking and control group was supported(Rt: F==7.320, p=.000 Lt: F=10.623, p=.000). In conclusion, in has been appeared that the lower extremities exercise and wearing elastic compression stocking have effedted in relieving low extremity edema and pain scale for nurses.

A Basic Study for Development of Clinical Practice Guidelines of Korean Medicine in Autism Spectrum Disorder -Based on Pre-existing Clinical Practice Guidelines of Autism Specturm Disorder- (자폐스펙트럼장애의 치료에 대한 한의 임상 가이드라인 개발을 위한 기초연구 -기존에 개발된 자폐스펙트럼장애 가이드라인을 중심으로-)

  • Kim, Sang Min;Lee, Jin Yong;Lee, Sun Haeng;Chang, Gyu Tae
    • The Journal of Pediatrics of Korean Medicine
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    • v.31 no.1
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    • pp.52-62
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    • 2017
  • Objectives The purpose of this study is to review pre-existing clinical practice guidelines for autism spectrum disorders, and refer those in developing a new practice guideline. Methods A total of 9 existing clinical practice guidelines for autism spectrum disorder developed from 2010 to 2016 were searched by Google scholar and Pubmed, and were reviewed those literatures in three parts: general, diagnosis & evaluation, and intervention. Results There were no consistency in the recommendation methods of 9 clinical care guidelines (such as the method of rating and recommendation intensity for diagnosis, evaluation, and treatment). However, in the diagnosis and evaluation section, frequently used evaluation and diagnostic tools are mentioned in most clinical practice guidelines, and the types of pharmacologic and non-pharmacological treatments that are mainly recommended in treatment are equally mentioned in most clinical practice guidelines could confirm. Conclusions 1. Some guideline recommendations are graded according to each criterion. Recommendations presented in various databases were based on systematic reviews or other literatures. The most utilized database were PsycINFO, CINAHL, Cochrane. 2. DSM-5 and ICD-10 were the most common used diagnostic criteria, and DSM-IV was used as a diagnostic standard in the guideline published before 2013. The tools used for diagnosis and evaluation were also varied. However, most recommended ones were ADI-R, ADOS-G, and DISCO. 3. Treatment was largely divided into pharmacological intervention and non-pharmacological intervention. In some guideline, the interventions were divided into pediatric and adult. Most of the pharmacological interventions were not recommended due to lack of evidence, but in cases in which specific symptoms were aimed, they recommended to seek professional help. 4. In addition to interventions, each guideline referred to supportive interventions that may be helpful in the daily life of patients with ASD, which may need to be addressed in future clinical guidelines.

Effects of Light Therapy on Stress, Depression, Quality of Sleep and Quality of Life in Middle-Aged Women: A Randomized Controlled Trial (빛 요법이 중년여성의 스트레스, 우울, 수면의 질 및 삶의 질에 미치는 효과: 무작위 대조군 연구)

  • Jang, Mi-Kyeong;Hur, Myung-Haeng
    • Journal of the Korea Convergence Society
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    • v.12 no.7
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    • pp.317-327
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    • 2021
  • This study is a randomized controlled trial to compare the effects of light therapy on stress, depression, sleep quality and quality of life in middle-aged women. The participants of this study were 56 middle-aged women who worked at the same office. Data collection period was from August 26 to September 13 for the control group and from September 16 to October 4 for the experimental group. Subjective stress, depression, quality of sleep and quality of life in middle-aged women were measured by Numeric Rating Scale (NRS), Center for Epidemiology studies of scale (CES-D), Verran & Synder-Halpern Sleep scale (VHS) and WHO Quality of Life Scale Abbreviated Version (WHOQOL-BREF). Stress index was measured using a Canopy9 RSA (IEMBIO, Gangwondo, Korea) equipment. The data were analyzed by mean, standard deviation, real number and percentage, χ2-test, t-test, repeated measures ANOVA and ANCOVA using IBM SPSS Statistics version 25.0. The results showed that the experimental group applying light therapy had significantly lower subjective stress (F=6.30, p<.001) and higher quality of life (F=2.80, p=.049) than the control group, There was no difference in objective stress index, depression, and sleep quality. As a result, light therapy is partially effective in subjective stress and quality of life for middle-aged women, and further research is needed on middle-aged women working in work environments with limited light exposure.

The Application of the Measurement of Heart Rate and Velocity during Training to Assess Racing Performance in Thoroughbred Horses (더러브렛 경주마에서 운동능력 평가를 위한 훈련 중 심박수 및 속도측정 수치 활용방안 연구)

  • Lee, Young-woo;Hwang, Hye-shin;Song, Hee-eun;Shim, Seung-tae;Ko, Jeong-ja;Seo, Jong-pil;Lee, Kyoung-kap
    • Journal of Veterinary Clinics
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    • v.36 no.1
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    • pp.62-67
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    • 2019
  • This study was performed to apply the measurement of heart rate and velocity in training horses for assessing race performance. Additionally, we aimed to identify parameters that can be used to evaluate the training level and exercise capacity. Eleven healthy 2- to 6-year-old Thoroughbreds were trained by the standard training program and heart rate and velocity were measured by using heart monitoring system and GPS. Regression analysis in heart rate and velocity data was performed to calculate velocity parameters. The mean maximal heart rate in gallop was $214{\pm}11bpm$. The mean $V_{140}$, $V_{180}$, $V_{200}$ and $VHR_{max}$ were $13.8{\pm}4.3km/h$, $37.5{\pm}3.8km/h$, $49.3{\pm}4.3km/h$ and $57.4{\pm}7.1km/h$ respectively. The mean $V_{140}$ of high performance racehorses was significantly higher than that of low performance racehorses (P < 0.05). Moreover, analyzing the correlation between velocity parameters and racing ability-related categories showed that $V_{140}$ was positively correlated with rating (P < 0.05), $V_{180}$ and $VHR_{max}$ were positively correlated with prize money per race (P < 0.05). Also, $V_{140}$ was significantly correlated with G1F (P < 0.05). The results of this study have shown that the measurement of heart rate and velocity during training could be useful methods to assess fitness for races or performance potential. Especially, $V_{140}$ is a good parameter to evaluate a performance of racehorses in Korea.

Fire Risk Rating Evaluation of Organic Insulation Materials (유기 단열재의 화재위험성 등급 평가)

  • You, Ji Sun;Jeon, Nam;Chung, Yeong-jin
    • Applied Chemistry for Engineering
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    • v.32 no.4
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    • pp.417-422
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    • 2021
  • In this study, poly isocyanurate foam (PIR), poly urethane foam (PUR), and phenol foam (PF) of organic insulation materials were selected, and investigated using a cone calorimeter, as per ISO 5660-1. Standard materials (PMMA) were used to standardize the fire hazard assessment, and the fire risk was classified and evaluated by Chung's equations-III and IV. The fire performance index-II value of Chung's equations-II was the highest value with PF of 14.77 s2/kW. And the PUR was 0.08 s2/kW, the lowest value of fire performance index-II value. The fire growth index-II value was the lowest value with PF of 0.01 kW/s2. And the PUR was 1.14 kW/s2, the highest value of fire growth index-II value. The fire performance index-III (FPI-III) of Chung's equations-III had the lowest value for PUR (0.11) and the highest for PF (20.23). The PUR showed the highest value of the fire growth index-III (FGI-III) as 14.25, while the PF exhibited 0.13 regarded as the safest materials. The fire risk index-IV (FRI-IV) value of Chung's equation-IV was in the following order: PUR (130.03) >> PIR (19.13) > PMMA (1.00) > PF (0.01). Therefore, it was concluded that the fire risk associated with PF is the lowest, whereas that associated with PUR is the highest.

A study on the policy conflict structure to Identify Demand for Regulatory Innovation in OTT Industry (OTT산업의 규제혁신 수요 파악을 위한 정책 갈등구조 분석)

  • Choi, HaeOk;Lee, KwangHo;Ha, ReeDa
    • Journal of Digital Convergence
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    • v.20 no.2
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    • pp.1-8
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    • 2022
  • Although the OTT industry is an area that needs urgent policy response as a priority area under the new industry regulatory reform master plan, various issues are occurring due to the lack of related institutional infrastructure. Therefore, this study aims to analyze the policy conflict structure in which regulatory obstacles and delays occur by listening to the opinions of major stakeholders and using the Q methodology to identify the regulatory innovation demand of the OTT industry. The analysis results are as follows. The analysis results are as follows. First, in the implementation of OTT-related policies, it is necessary to improve the standard system for the method of settlement of copyright fees. Second, it is required to improve the support method that can reduce the burden of OTT operators' fund. Third, it is necessary to supplement the system by changing the regulatory application method for potential regulatory issues related to zero-rating. This study can be utilized in the process of introducing a system in which various stakeholders are connected and developed in a complex manner in the process of regulatory innovation in new industries and services.

Relationship Between Psychological Factors and Pain Intensity in Temporomandibular Disorders with or without Central Sensitization: A Cross-Sectional Observational Study Using Multiple Regression Analysis

  • Sebastian Eustaquio Martin Perez;Isidro Miguel Martin Perez;Jose Andres Diaz Cordova;Leidy Milena Posada Cortes
    • Journal of Oral Medicine and Pain
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    • v.48 no.3
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    • pp.87-95
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    • 2023
  • Purpose: To quantify the relationship between perceived pain intensity and psychological variables in a sample of participants with temporomandibular disorder, with or without central sensitization (CS). Methods: A cross-sectional study with nonprobability convenience sampling was conducted from January 1, 2022, to June 30, 2023. Pain intensity (Numeric Pain Rating Scale), anxiety (State-Trait Anxiety Questionnaire, STAI), catastrophizing (Pain Catastrophizing Scale, PCS), perceived stress (Perceived Stress Scale, PSS), and sleep quality (Pittsburgh Sleep Quality Index, PSQI) were assessed. Statistical analysis was performed using IBM SPSS Statistics for Windows, Version 20.0 (IBM Co.), which included descriptive and normality analyses and the calculation of strength of multiple correlational regression. Results: A total of 52 (n=34 female 65.4%; n=18 male 34.6%) subjects with diagnosis of temporomandibular disorders (TMD) were finally included. A total of 26 participants (n=26, 50.0%) were cases suffered from CS (TMD-CS mean=46.62±11.24) while the remaining participants (n=26, 50.0%) were the controls (TMD-nCS mean=26.77, standard deviation [SD]=8.42). The pain intensity was moderate in both groups TMDCS (mean=7.62, SD=0.83) and TMD-nCS (mean=7.05, SD=0.86), anxiety (TMD-CS STAI mean=53.27, SD=11.54; TMD-nCS STAI mean=49, SD=11.55), catastrophizing (TMD-CS PCS mean=46.27, SD=9.75; TMD-nCS PCS mean=26.69, SD=4.97), perceived stress (TMDCS PSS mean=30.35, SD=4.91; TMD-nCS PSS mean=26.12, SD=6.60) and sleep quality (TMD-CS PSQI mean=15.81, SD=3.65; TMD-nCS PSQI mean=12.77, SD=2.76) levels were measured in both groups. In TMD-CS and TMD-nCS, higher anxiety levels were moderately and significantly associated with greater pain intensity β=0.4467 (t=2.477, p=0.021) and β=0.5087 (t=2.672, p=0.014). Nevertheless, catastrophizing, perceived stress and sleep quality were not associated to pain intensity in neither of group. Conclusions: In both TMD-CS and TMD-nCS patients, elevated anxiety levels were moderately and significantly associated with increased pain intensity. However, heightened levels of pain catastrophizing, perceived stress, and poor sleep quality were not significantly associated with increased pain intensity in either of the two analyzed groups.