Object : Since autonomic nerve system dysfunction was known as the mechanism of panic disorder, many researchers used heart rate variability (HRV) as means of measuring autonomic nerve function of patients with panic disorder. We aimed to examine the effect of paroxetine medication for 3 months on symptom improvement and change of heart rate variability of the patients with panic disorder. Methods : The subjects were patients with panic disorder who visited the psychiatric outpatient clinic of Samsung Medical Center in Seoul. We included panic disorder patients who were aged from 20 to 50 and in normal BMI range (from 18 to 30) to minimize the effect of age and weight on HRV data. We excluded the patients with EKG abnormalities, hypertension or other major psychiatric disorders. They took 20-40 mg paroxetine medication a day for 3 months. Alprazolam was used only during the first month to control the acute panic symptoms and was tapered off after that. We measured the acute panic inventory (API), Hamilton rating scale for anxiety and depression (HAM-A & HAM-D), Spielberger state-trait anxiety inventory (STAIS, STAIT), and Beck depression inventory (BDI) in order to assess clinical improvement of the patients. And we measured time and frequency domain HRV in the resting, standing and cognitive stress states to assess the change of HRV. All measurements were done before and after paroxetine treatment. Result : After paroxetine medication, patients showed significant improvement in all psychiatric scales. In time domain of HRV, standard deviations of all R-R intervals (SDNN) were significantly increased in all states. In frequency domain of HRV, the ratio of high frequency to total power (HF/TP) in the standing state was significantly increased. Conclusion : After 3 months paroxetine medication, panic disorder patients showed significant clinical improvement and change in HRV data such as SDNN in all states and HF/TP ratio in the standing state. This result suggests that paroxetine medication is effective for the improvement of autonomic nerve system dysfunction in panic disorder patients.
The study empirically analyses a linear relationship between terrestrial advertising rates and viewer ratings. Consistent with the results of preceding studies, the present study finds a convex relationship between standard advertising rates and viewer ratings. However, after all other sales practices are taken into account, a linear relationship is documented between per-minute advertising revenue and viewer ratings. Absent the exact functional relationship between the two, it is hard to evaluate accurately how efficiently or inefficiently the current GS System has operated, but it tells us that a certain level of market mechanism prevailed within the system. The findings are consistent with the 1 Public-1 Private Media Representative alternative among many alternatives currently sought by the KCC should we accept the premise that the public aspect is as equally important as, if not more important than, the efficiency aspect of terrestrial broadcasting.
Park, Yang Mi;Ahn, Yong-Woo;Jeong, Sung-Hee;Ju, Hye-Min;Jeon, Hye-Mi;Kim, Kyung-Hee;Ok, Soo-Min
Journal of Oral Medicine and Pain
/
v.44
no.4
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pp.160-168
/
2019
Purpose: To search the salivary factors that objectively indicate an pain in myalgia patients with temporomandibular joint disorder (TMD) and determine the possibility of the factors as pain-biomarkers. Methods: Participants consisted of pain-free 15 persons (male 7, female 8, mean age±standard deviation (SD); 26.8±16.04 years) and 45 myalgia patients with TMD (male 21, female 24, mean age±SD; 27.98±13.01 years). They were divided into a pain-free group (numerical rating scale [NRS] score 0), a mild pain group (NRS 1-4), a moderate pain group (NRS 5-6), and a severe pain group (NRS 7-10) and members of all groups were age, sex matched. Interleukin-8 (IL-8) and matrix metalloprotease 9 (MMP-9) were selected as pain biomarkers, by searching the Gene Expression Omnibus database and analyzing pain-related genes. Enzyme-linked immunosorbent assays were used to measure the concentration of IL-8 and MMP-9 in the patients' saliva. Results: IL-8 and MMP-9 levels were statistically significantly higher in pain groups than in the pain-free group. Greater differences were observed in patients with acute pain (with painful duration under 3 months) than in the control group and in female patients than in male. Conclusions: Salivary IL-8 and MMP-9 may play a role as biomarkers of myalgia in patients with TMD.
Subsyndromal depression (SSD) is found to be more prevalent than major depressive disorder (MDD) and minor depressive disorder (MnDD). SSD is also associated with adverse clinical outcomes, increased risk of suicide, increased social dysfunction and disability, increased risk for future mood disorders, and increased uses of medical and mental health services. DSM-IV diagnostic criteria are not suitable for capturing SSD. Although there is no agreement on gold standard to define SSD so far, three definitions of SSD are available. First, SSD is defined as having two or more current depressive symptoms without core depressive symptoms (depressive mood or loss of interest) and with time threshold (most of the day and nearly every day over at least two weeks). Second, SSD is defined as having two or more current depressive symptoms with core depressive symptoms and without time threshold. Third, SSD is defined by using cutoff points of depression rating scales. SSD may represent a prodromal, residual, or interepisode symptomatic state in the course of MDD and MnDD. More than a half of SSD patients became any type of depressive disorders (SSD, MnDD and MDD) at 1 year. SSD may represent a discrete category of its own, without prior or consequent episodes of MDD. Considering clinical significance of SSD such as its high prevalence, significant psychosocial impairment and chronicity and serious outcomes, researchers and clinicians should be more vigilant in capturing and caring for patients with SSD.
Transactions of the Korean Society of Automotive Engineers
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v.20
no.5
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pp.81-87
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2012
New car assessment program (NCAP) originated from USNCAP in 1979 has been implemented in several countries or markets, for instance USA, Europe, Korea, Japan, China and Australia. NCAP has contributed greatly to reduce accidental tolls. But recently, NCAP performance has no distinction between cars because manufacturer have been continuously developed to improve NCAP performance. Therefore, NHTSA announced new USNCAP protocol becoming effective from MY2011. NHTSA had carried out many NCAP tests based on the new test protocol and announced these test results. In this paper, USNCAP test results were reviewed by statistical method. This review was focused on passenger cars and frontal crash test results in order to investigate effect of changes in new NCAP protocol. There are two key changes, one is sited female dummy in passenger position, the other is enlarged to 4 scoring body regions in each dummy. Results of this review were summarized as followings. Performance in Passenger (12.5%) is lower than Driver's (50%) for number of 5 star vehicle. Neck injury criterion is dominant to NCAP star rating for both dummies in the mean sense. For standard deviation, chest deflection is showed largest value in driver dummy but neck injury criterion is showed for passenger's. DKAB and PKAB were equipped 28.1% and 6.2%, respectively. Consequently, the countermeasure for new USNCAP frontal crash test is essential to control well dummy kinematics with some safety features including KAB to reduce neck injuries.
Journal of the Korean Society of Clothing and Textiles
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v.38
no.2
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pp.137-146
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2014
The practice of sustainability is an important subject to integrate into the management, product planning, manufacturing by textile and fashion companies as well as consumption by end-users. This study shows an evaluation scale designed to assess the practical cases in order to suggest efficient and systematic methods to fulfill the practice of sustainability in textile and fashion companies. First, companies should practice environmental sustainability to use eco-friendly material and cleaner production, protect the environment, and save natural resources. Second, social sustainability is required to fulfill social responsibility and ethical needs. Third, companies should perform various innovative activities, transparency in management, fair competition and economic contribution in the local community in order to maintain economic sustainability to survive in industry. Finally, cultural sustainability should be fulfilled by textile and fashion companies as part of the intellectual-cultural industry in a way that increases the importance of ethnic and cultural diversity. Textile and fashion companies should fulfill four environmental, social, and economic cultural sustainable subjects in a balanced method to accomplish sustainability. The concerns and practices of environmental sustainability are comparatively highly rated due to the analysis of the evaluation scale. However, cultural sustainability (a need of the times) is poorly rated and needs more attention. Therefore, the evaluation scale can be used as a standard tool to fulfill the sustainability of companies and brands from the viewpoint of improving poor and insufficiently sustainable items as well as balancing sustainability management.
We reviewed the results of arthroscopic surgery in patients with rotator cuff disease. Arthroscopic subacromial decompression(ASD) was performed on 22 patients with rotator cuff disease who had not responded to nonoperative measures. In the patients who had a complete tear of the rotator cuff(four of ten Neer's stage III patients), mini-open repair also was performed. Results were determined by questioning patients about their satisfaction with the outcome of surgery and by functional assessment of the shoulder with the parameters of pain, function, and range of motion according to the UCLA shoulder rating scale. The average follow-up was 21 months. The results were sixteen(72%) excellent, three(14%) good, two(9%) fair, and one(5%) poor. The following variables were analyzed to assess their influence on final outcome; duration of preoperative symptoms, Neer's stage(extent of damage to the cuff), type of acromion. Satisfactory results were achieved in thirteen of fourteen patients(93%) who had duration of preoperative symptoms below one year, and in four of six(67%) above 2 years. And satisfactory results were achieved in eleven of twelve patients(92%) who had Neer's stage II and in eight of ten(80%) stage III and achieved in six of seven patients(86%) who had Bigliani's acromion type I, in nine of eleven(82%) type II, and in four of four(100%) type III. There are multiple factors that may influence the recovery after ASD or the eventual outcome. However, although there is still a controversy about the pathogenesis of rotator cuff disease, We found that arthroscopic subacromial decompression and mini-open repair in patients with rotator cuff disease were well enough documented to be considered a standard treatment.
Purpose: It is difficult to calculate frame U-value because of the two reason. First is selection of air properties in cavity. Second is calculation method in window frame. For this reason, it is important to decide cavity properties in window frame. However, international standards offered different method(ISO 15099, ISO 10077) and air properties was changed according to the two methods. The aim of this study was to suggest method for deriving accurate frame U-value using international standard methods and CFD simulation. Method: First, this study conducted analysis calculation method of ISO 15099 and ISO 10077. And, CFD simulation conducted based on same condition. Finally, ISO calculation and CFD simulation results were verified through comparison with real experiment results. Result: The results show that effective conductivity of ISO 15099 was the highest value. ISO 10077 and CFD result followed. The convergent values of ISO 10077 was the highest. ISO 15099 and CFD followed. ISO calculation reflecting CFD simulation results will reduce error with experimental results.
The objective of this study was to discover the effects of the short-term home visiting physical therapy program involving patients with some chronic brain disorders at Gimhae City, Kyongnam. Recovery of activities of daily living (ADL) is a very important factor of rehabilitative procedures, and Functional Independence Measure (FIM) is a useful standard of evaluation for it. The FIM is widely used in brain disorder research because it measures real functional activities of daily living. We applied the physical therapy exercise program twice per week (10~15 times repeatedly); a warm-up and cool down exercise performed every ten minutes by active & active-assistive ROM and stretching exercises. Main exercises were composed of getting up & laying down in bed, standing training, walking exercise in the room, and window or wall sliding exercise using affected upper limbs for a total duration of 30 minutes. We collected the data from 20 patients with chronic brain disorders at his/her home and analyzed by means of SPSS/PC+ program (Ver. 10.0). After the six week long physical therapy exercise program, the average was $56.10{\pm}22.59$ point compared with initial $50.55{\pm}19.12$ point by FIM, improved functional ADL ability about 5.55 point, and these changed scores were statistically significant (p=.000). We also studied another factor regarding patient's satisfaction. The majority of subjects (10 people) rated the program with the maximum score of ten points (50.0%), and three people rated it a seven point program (15.0%), the other two subjects gave a rating of nine and eight points (10.0%). Because the program was effective at improving the physical ADL ability and satisfaction of each subject, we suggest continual development and implementation of a home visiting physical therapy program. Further study should involve a longer period of observation with a larger population that is involved in an individually designed home physical therapy program.
Coupled thermo-mechanical analysis of reinforced concrete slab at elevated temperatures from a fire accounting for nonlinear thermal parameters is carried out. The main focus of the paper is put on a one-way continuous reinforced concrete slab exposed to fire from the single (bottom) side as the most typical working condition under fire loading. Although contemporary techniques alongside the fire protection measures are in constant development, in most cases it is not possible to avoid the material deterioration particularly nearby the exposed surface from a fire. Thereby the structural fire resistance of reinforced concrete slabs is mostly influenced by a relative distance between reinforcement and the exposed surface. A parametric study with variable concrete cover ranging from 15 mm to 35 mm is performed. As the first part of a one-way coupled thermo-mechanical analysis, transient nonlinear heat transfer analysis is performed by applying the net heat flux on the exposed surface. The solution of proposed heat analysis is obtained at certain time steps of interest by α-method using the explicit Euler time-integration scheme. Spatial discretization is done by the finite element method using a 1D 2-noded truss element with the temperature nodal values as unknowns. The obtained results in terms of temperature field inside the element are compared with available numerical and experimental results. A high level of agreement can be observed, implying the proposed model capable of describing the temperature field during a fire. Accompanying thermal analysis, mechanical analysis is performed in two ways. Firstly, using the guidelines given in Eurocode 2 - Part 1-2 resulting in the fire resistance rating for the aforementioned concrete cover values. The second way is a fully numerical coupled analysis carried out in general-purpose finite element software DIANA FEA. Both approaches indicate structural fire behavior similar to those observed in large-scale fire tests.
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