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Epidemiology and Clinical Characteristics of Parainfluenza Virus Type 4 in Korean Children: a Single Center Study, 2015-2017 (소아에서 파라인플루엔자 바이러스 4형의 역학 및 임상 양상에 대한 단일기관 연구: 2015-2017)

  • Sohn, Young Joo;Choi, Youn Young;Yun, Ki Wook;Choi, Eun Hwa;Lee, Hoan Jong
    • Pediatric Infection and Vaccine
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    • v.25 no.3
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    • pp.156-164
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    • 2018
  • Purpose: We aimed to identify the epidemiology and the clinical characteristics of human parainfluenza virus type 4 (HPIV-4) infection compared to HPIVs 1-3 infections in Korean children. Methods: We reviewed medical records of children with HPIV infection who visited Seoul National University Children's Hospital from 2015 to 2017. Detection of respiratory viruses was performed using real time-polymerase chain reaction (rt-PCR), which could differentiate HPIVs 1-4. Diagnosis was classified as a febrile illness, upper respiratory tract infection (URI), croup, bronchiolitis, or pneumonia. The epidemiology, demographic features, and clinical characteristics among HPIV types were compared. The clinical data were analyzed only for the previously healthy children. Results: Of the 472 children diagnosed with HPIV infection, 108 (22.9%) were previously healthy: 24 (22.2%), 19 (17.6%), 39 (36.1%), and 26 (24.1%) in HPIV types 1, 2, 3, and 4, respectively. The median age of children with HPIV-4 infection was 11 (0-195) months: the proportion of children aged < 2 years and 2 to < 5 years were 65.4% and 19.2%, respectively. Clinical diagnoses of HPIV-4 infection were bronchiolitis (38.5%), pneumonia (30.8%), and URI (30.8%). Croup was the most prevalent in HPIV-2 (21.1%) and none in HPIV-4 infection (P=0.026). Hospital admission rates among HPIV types were not significantly different (P>0.05). Conclusions: We observed seasonal peak of HPIV-4 infection in 2015 and 2017. HPIV-4 was a common respiratory pathogen causing lower respiratory tract infection in hospitalized children.

The Tresnds of Artiodactyla Researches in Korea, China and Japan using Text-mining and Co-occurrence Analysis of Words (텍스트마이닝과 동시출현단어분석을 이용한 한국, 중국, 일본의 우제목 연구 동향 분석)

  • Lee, Byeong-Ju;Kim, Baek-Jun;Lee, Jae Min;Eo, Soo Hyung
    • Korean Journal of Environment and Ecology
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    • v.33 no.1
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    • pp.9-15
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    • 2019
  • Artiodactyla, which is an even-toed mammal, widely inhabits worldwide. In recent years, wild Artiodactyla species have attracted public attention due to the rapid increase of crop damage and road-kill caused by wild Artiodactyla such as water deer and wild boar and the decrease of some species such as long-tailed goral and musk deer. In spite of such public attention, however, there have been few studies on Artiodactyla in Korea, and no studies have focused on the trend analysis of Artiodactyla, making it difficult to understand actual problems. Many recent studies on trend used text-mining and co-occurrence analysis to increase objectivity in the classification of research subjects by extracting keywords appearing in literature and quantifying relevance between words. In this study, we analyzed texts from research articles of three countries (Korea, China, and Japan) through text-mining and co-occurrence analysis and compared the research subjects in each country. We extracted 199 words from 665 articles related to Artiodactyla of three countries through text-mining. Three word-clusters were formed as a result of co-occurrence analysis on extracted words. We determined that cluster1 was related to "habitat condition and ecology", cluster2 was related to "disease" and cluster3 was related to "conservation genetics and molecular ecology". The results of comparing the rates of occurrence of each word clusters in each country showed that they were relatively even in China and Japan whereas Korea had a prevailing rate (69%) of cluster2 related to "disease". In the regression analysis on the number of words per year in each cluster, the number of words in both China and Japan increased evenly by year in each cluster while the rate of increase of cluster2 was five times more than the other clusters in Korea. The results indicate that Korean researches on Artiodactyla tended to focus on diseases more than those in China and Japan, and few researchers considered other subjects including habitat characteristics, behavior and molecular ecology. In order to control the damage caused by Artiodactyla and to establish a reasonable policy for the protection of endangered species, it is necessary to accumulate basic ecological data by conducting researches on wild Artiodactyla more.

Evaluation of Dental Hygienist Job Validity according to Judgment Standard of Medical Practice in Medical Law (의료행위 기준에 따른 치과위생사 직무 타당도 평가)

  • Bae, Soo-Myoung;Shin, Sun-Jung;Lee, Hyo-Jin;Shin, Bo-Mi
    • Journal of dental hygiene science
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    • v.18 no.6
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    • pp.357-366
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    • 2018
  • The purpose of this study was to evaluate the validity of dental hygienist job according to judgment standard of medical practice in medical law. In this study, we conducted a self-administered questionnaire survey to evaluate the validity of dental hygienist job for 12 professors of dental college in Gangneung-Wonju National University from November 10 to 20, 2017. We investigated whether the dental hygienist job conforms to the three criteria of medical practice such as disease prevention and treatment, patient care, and health hazard. The response rates were scored and classified into four categories according to the final score. As a result of this study, dental hygienist job are classified into four categories according to judgment standard of medical practice. The higher the level of the category, the higher the degree of difficulty, and the higher the level of expertise and skills required. More than 50% of respondents answered that measuring the gingival pocket, bleeding on probing, professional tooth cleaning, oral health education, counseling after dental treatment are all three criteria for medical treatment. And these were classified into Level 4 group which requires the difficulty and expertise in the final score 4.3. It is necessary to develop and utilize standardized guidelines on the level of knowledge, education, and qualification standards required for dental practice in order to effectively allocate work among the dental personnel while ensuring the health rights of patients in the dental clinic field in Korea. In addition, there is a need to evaluate the various aspects of cost effectiveness, dental health service productivity, and health promotion contribution to dental hygienist jobs, And based on this evidence, it is necessary to continue to expand and adjust the dental hygienist job and to reorganize the dental workforce system.

Effects of Local Cooling and Root Pruning on Budding and Local Heating on Heating Energy Consumption in Forcing Cultivation of Strawberry (딸기 촉성재배 시 국소 냉방 및 단근처리와 국소난방이 화방출뢰와 난방에너지소비에 미치는 영향)

  • Kwon, Jin Kyung;Kang, Suk Won;Paek, Yee;Moon, Jong Pil;Jang, Jae Kyung;Oh, Sung Sik
    • Journal of Bio-Environment Control
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    • v.28 no.1
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    • pp.46-54
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    • 2019
  • Experiments of local cooling and heating on crown and root zone of forcing cultivation of strawberry 'Seolhyang' using heat pump and root pruning before planting were conducted. During the daytime, the crown surface temperature of the crown local cooling treatment was maintained at $18{\sim}22^{\circ}C$. This is suitable for flower differentiation, while those of control and root zone local cooling treatment were above $30^{\circ}C$. Budding rate of first flower clusters and initial yields were in the order of crown local cooling, root zone local cooling and control in root pruning plantlet and non pruning plantlet, except for purchase plantlet. Those of root pruning plantlet were higher than those of non pruning plantlet. These trends were evident in the yield of the first flower cluster until February 14, 2018, and the effect of local cooling and root pruning decreased from March 9, 2018. The budding rates of the second flower cluster according to the local cooling and root pruning treatments were not noticeable compared to first flower cluster but showed the same tendency as that of first flower cluster. In the heating experiment, root zone local heating(root zone $20^{\circ}C$+inside greenhouse $5^{\circ}C$) and crown local heating(crown $20^{\circ}C$+inside greenhouse $5^{\circ}C$) saved 59% and 65% of heating fuel, respectively, compared to control(inside greenhouse $9^{\circ}C$). Considering the electric power consumption according to the heat pump operation, the heating costs were reduced by 55% and 61%, respectively.

Effects of Artificial CO2 Release in Soil on Chlorophyll Content and Growth of Pinus densiflora and Quercus variabilis Seedlings (토양 내 인위적인 이산화탄소 누출에 따른 소나무와 굴참나무 묘목의 엽록소 함량과 생장 반응)

  • Kim, Hyun-Jun;Han, Seung Hyun;Kim, Seongjun;Chang, Hanna;Son, Yowhan
    • Journal of Korean Society of Forest Science
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    • v.107 no.4
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    • pp.351-360
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    • 2018
  • This study was conducted to analyze the responses of chlorophyll contents and growth of Pinus densiflora and Quercus variabilis seedlings on distance from the well and $CO_2$ flux after the artificial $CO_2$ release. From June 1 to 30, 2016, $CO_2$ gas was injected at the rate of $6L\;min^{-1}$ at the study site in Eumseong. Chlorophyll content was analyzed in the middle of July, 2016, and root collar diameter (RCD), height (H), and biomass were measured in May and December, 2016 after planting 2-year-old P. densiflora and 1-year-old Q. variabilis seedlings in May, 2015. The chlorophyll content of P. densiflora seedlings did not show a significant correlation with $CO_2$ flux, whereas the chlorophyll content of Q. variabilis seedlings showed a significant negative correlation with increasing $CO_2$ flux (P<0.05). The RCD and H growth rates of both species showed the significant difference in the distance from the well of the $CO_2$ anthropogenic release treatment. In particular, the RCD and H growth rate of P. densiflora seedlings and the RCD growth rate of Q. variabilis seedlings increased significantly as the seedlings were closer to the well, but the H growth rate of Q. variabilis seedlings decreased significantly. In addition, as the $CO_2$ concentration in the ground increases, ${\Delta}R/S$ ratio increases in both species, suggesting that the high $CO_2$ concentration in the soil promotes carbon distribution relative to the root part. The results of this study can be used as data necessary to monitor the $CO_2$ leakage and physiological and growth responses of both species to leakage of stored $CO_2$ in the future.

Growth and Blood Characteristics of Red Sea Bream Pagrus major by Starvation and Stocking Density during Red Tide (적조발생시기 참돔의 절식과 사육밀도에 따른 성장과 혈액성상)

  • Kim, Won-Jin;Lee, Jeong-Yong;Shin, Yun-Kyung;Won, Kyoung-Mi
    • Korean Journal of Ichthyology
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    • v.30 no.4
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    • pp.194-204
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    • 2018
  • In order to minimize the damage on the red sea bream Pagrus major by a harmful dinoflagellate Cochlodinium polykrikoides, we investigated the effect of feeding, starvation and stocking density on the survival rate, growth, growth restoration and physiological response of P. major exposure to C. polykrikoides. The experimental groups were divided into three groups such as F-HD (feeding and high density with $6.4kg/m^3$), S-HD (starvation and high density with $6.4kg/m^3$) and S-LD (starvation and low density with $3.2kg/m^3$) according to stocking density and starvation in marine cage ($11m{\times}11m{\times}5m$). The F-HD was fed throughout the experiment for 9 weeks, whereas S-HD and S-LD were not fed for 5 weeks and then refeeding for 4 weeks. Survival rate was the lowest in F-HD (85.5%) and S-LD was the highest (97.3%). The growth rates of S-HD and S-LD were significantly lower than F-HD during starvation period for 4 weeks, but rapidly recovered after feeding. The nutritional status such as ALB, TP, TCH, TG were similar to tendency of growth data. Ht, Hb, AST, ALT and GLU levels were significantly higher in the F-HD than in the starvation groups at the same time (in 3 week) during starvation period. But starvation groups did not differ during starvation period. As a result, F-HD is more sensitive to stress than S-HD and S-LD. Thus, during C. polykrikoides bloom period, starvation and stocking density control can help survival and growth restoration of the red sea bream.

An investigation Of IntraFraction Motion Correction For Lung Stereotactic Body Radiation Therapy By Using IntraFraction Cone Beam Computed Tomography (폐암 환자의 정위적 체부 방사선 치료 시 IntraFraction CBCT를 이용한 치료 중 자세 오차 교정에 대한 고찰)

  • Song, Hyeong Seok;Cho, Kang Chul;Park, Hyo Kuk;Yoon, Jong Won;Cho, Jung Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.31 no.1
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    • pp.67-74
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    • 2019
  • Purpose: The purpose is to correct for position errors caused by long treatment times. By correcting the target motion that can occur during lung SBRT using IntraFraction CBCT. Methods and materials: We analyzed retrospectively the IFM data of 14 patients with two treatment arc in the treatment plan for lung cancer with stereotactic radiotherapy. An IntraFraction Motion was applied to the Arccheck phantom to acquire the Gamma index data. Results : IntraFraction Motion during the first treatment arc is in the left-right(LR), superiorinferior(SI), anterior-posterior(AP) directions were $0.16{\pm}0.05cm$, 0.72 cm(max error), $0.2{\pm}0.14cm$, 1.26 cm, $0.24{\pm}0.08cm$, 0.82 cm and rotational directions was $0.84{\pm}0.23^{\circ}$, $2.8^{\circ}$(pitch), $0.72{\pm}0.23^{\circ}$, $2.5^{\circ}$(yaw), $0.7{\pm}0.19^{\circ}$, $2^{\circ}$(roll). IntraFraction Motion during the second treatment arc is in the LR, SI, AP directions were $0.1{\pm}0.04cm$, 0.37 cm, $0.14{\pm}0.17cm$, 2 cm, $0.12{\pm}0.04cm$, 0.5 cm and rotational directions was $0.45{\pm}0.12^{\circ}$, $1.3^{\circ}$, $0.37{\pm}0.1^{\circ}$, $1^{\circ}$, $0.35{\pm}0.1^{\circ}$, $1.2^{\circ}$. Gamma index pass rates were $82.64{\pm}10.51%$, 48.4 %. Conclusions : In this study, we examined the validity of IntraFraction Motion correction in lung SBRT and the efficiency of IntraFraction CBCT. Due to the nature of SBRT treatment, IFM may increase due to the increased treatment time. It is believed that the increase in IFM with the increase in treatment time can be improved with the use of FFF Beam and additional position correction using CBCT during treatment.

Carbon Reduction by and Quantitative Models for Landscape Tree Species in Southern Region - For Camellia japonica, Lagerstroemia indica, and Quercus myrsinaefolia - (남부지방 조경수종의 탄소저감과 계량모델 - 동백나무, 배롱나무 및 가시나무를 대상으로 -)

  • Jo, Hyun-Kil;Kil, Sung-Ho;Park, Hye-Mi;Kim, Jin-Young
    • Journal of the Korean Institute of Landscape Architecture
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    • v.47 no.3
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    • pp.31-38
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    • 2019
  • This study quantified, through a direct harvesting method, storage and annual uptake of carbon from open-grown trees for three landscape tree species frequently planted in the southern region of Korea, and developed quantitative models to easily estimate the carbon reduction by tree growth for each species. The tree species for the study included Camellia japonica, Lagerstroemia indica, and Quercus myrsinaefolia, for which no information on carbon storage and uptake was available. Ten tree individuals for each species (a total of 30 individuals) were sampled considering various stem diameter sizes at given intervals. The study measured biomass for each part of the sample trees to quantify the total carbon storage per tree. Annual carbon uptake per tree was computed by analyzing the radial growth rates of the stem samples at breast height or ground level. Quantitative models were developed using stem diameter as an independent variable to easily calculate storage and annual uptake of carbon per tree for study species. All the quantitative models showed high fitness with $r^2$ values of 0.94-0.98. The storage and annual uptake of carbon from a Q. myrsinaefolia tree with dbh of 10 cm were 24.0 kg and 4.5 kg/yr, respectively. A C. japonica tree and L. indica tree with dg of 10 cm stored 11.2 kg and 8.1 kg of carbon and annually sequestered 2.6 kg and 1.2 kg, respectively. The above-mentioned carbon storage equaled the amount of carbon emitted from the gasoline consumption of about 42 L for Q. myrsinaefolia, 20 L for C. japonica, and 14 L for L. indica. A tree with the diameter size of 10 cm annually offset carbon emissions from gasoline use of approximately 8 L for Q. myrsinaefolia, 5 L for C. japonica, and 2 L for L. indica. The study pioneers in quantifying biomass and carbon reduction for the landscape tree species in the southern region despite difficulties in direct cutting and root digging of the planted trees.

The Quantity and Pattern of Leaf Fall and Nitrogen Resorption Strategy by Leaf-litter in the Gwangneung Natural Broadleaved Forest (광릉숲 천연활엽수림의 수종별 낙엽 현상과 질소 재전류 특성)

  • Kwon, Boram;Kim, Hyunseok;Yi, Myong Jong
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.21 no.3
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    • pp.208-220
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    • 2019
  • The seasonality of leaf fall has important implications for understanding the response of trees' phenology to climate change. In this study, we quantified the leaf fall pattern with a model to estimate the timing and speed of leaf litter according to species and considered the nutrient use strategy of canopy species. In the autumns of 2015 and 2016, leaf litter was collected periodically using 36 litter-traps from the deciduous forests in Gwangneung and sorted by species. The seasonal leaf fall pattern was estimated using the non-linear regression model of Dixon. Additionally, the resorption rate was calculated by analyzing the nitrogen concentration of the leaf litter at each collection time. The leaf litter generally began in early October and ended in mid-November depending on the species. At the peak time (T50) of leaf fall, on average, Carpinus laxiflora was first, and Quercus serrata was last. The rate of leaf fall was fastest (18.6 days) for Sorbus alnifolia in 2016 and slowest (40.8 days) for C. cordata in 2015. The nitrogen resorption rates at T50 were 0.45% for Q. serrata and 0.48% for C. laxiflora, and the resorption rate in 2015 with less precipitation was higher than in 2016. Since falling of leaf litter is affected by environmental factors such as temperature, precipitation, photoperiod, and $CO_2$ during the period attached foliage, the leaf fall pattern and nitrogen resorption differed year by year depending on the species. If we quantify the fall phenomena of deciduous trees and analyze them according to various conditions, we can predict whether the changes in leaf fall timing and speed due to climate change will prolong or shorten the growth period of trees. In addition, it may be possible to consider how this affects their nutrient use strategy.

Evaluation of a Rapid Diagnostic Antigen Test Kit Ribotest Mycoplasma® for the Detection of Mycoplasma pneumoniae (Mycoplasma pneumoniae 감염의 신속 항원 검사 키트 "Ribotest Mycoplasma®"의 진단적 평가)

  • Yang, Song I;Han, Mi Seon;Kim, Sun Jung;Lee, Seong Yeon;Choi, Eun Hwa
    • Pediatric Infection and Vaccine
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    • v.26 no.2
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    • pp.81-88
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    • 2019
  • Purpose: Early detection of Mycoplasma pneumoniae is important for appropriate antimicrobial therapy in children with pneumonia. This study aimed to evaluate the diagnostic value of a rapid antigen test kit in detecting M. pneumoniae from respiratory specimens in children with lower respiratory tract infection (LRTI). Methods: A total of 215 nasopharyngeal aspirates (NPAs) were selected from a pool of NPAs that had been obtained from children admitted for LRTI from August 2010 to August 2018. The specimens had been tested for M. pneumoniae by culture and stored at $-70^{\circ}C$ until use. Tests with Ribotest $Mycoplasma^{(R)}$ were performed and interpreted independently by two investigators who were blinded to the culture results. Results: Among the 215 NPAs, 119 were culture positive for M. pneumoniae and 96 were culture negative. Of the culture-positive specimens, 74 (62.2%) were positive for M. pneumoniae by Ribotest $Mycoplasma^{(R)}$, and 92 of the 96 (95.8%) culture-negative specimens were negative for M. pneumoniae by Ribotest $Mycoplasma^{(R)}$. When culture was used as the standard test, the sensitivity and specificity of Ribotest $Mycoplasma^{(R)}$ were 62.2% and 95.8%, respectively. Additionally, the positive predictive value, negative predictive value, and overall agreement rates with Ribotest $Mycoplasma^{(R)}$ were 94.9%, 67.2%, and 77.2%, respectively. Conclusions: A positive test result of Ribotest $Mycoplasma^{(R)}$ suggests a high likelihood of culture-positive M. pneumoniae infection. However, a negative test result should be interpreted with caution because nearly one-third of negative test results reveal culture-positive M. pneumoniae infections.