• 대한방사선기술학회지:방사선기술과학
• /
• 제22권1호
• /
• pp.21-26
• /
• 1999

To make a comparative analysis for clinical application of total hip replacement arthroplasty(THRA) using fluoroscopy, we have performed total hip replacement arthroplasty making 30 patients an object with general radiography and fluoroscopy respectively. The results are as follows : 1) Reexamination rate was 80% of patients and mean 3.9 sheets in the general radiography, where as it was 46.7% and 0.37 sheets in the fluoroscopy(p<0.01) 2) Add examination was 2 cases in the general radiography, but fluoroscopy was no add examination. 3) The total film sheet used was mean 10.16 in the general radiography and 6.73 in the fluoroscopy. 4) In the cause of reexmination and add examination, inaccurate position of patient accounted for 72.6% in the general radiography and poor exposure condition accounted for 45.5% in the fluoroscopy. Total hip replacement arthroplasty using the fluoroscopy decreased reexamination and add examination rate, for these reasons, this method was effective abatement of pain, exposured radiation dose, and examination time and so on.

• 음성과학
• /
• 제7권2호
• /
• pp.19-35
• /
• 2000

Speech evaluation and treatment planning for the patients with articulation disorders have traditionally been based on perceptual judgement by speech pathologists. Recently, various computerized speech analysis systems have been developed and commonly used in clinical settings to obtain the objective and quantitative data and specific treatment strategies. 10 dysarthric children (6 neurogenic and 4 functional dysarthria) participated in this experiment. Speech evaluation of dysarthria was performed in two ways; first, the acoustic analysis by Visi-Pitch and a Computerized Speech Lab and second, the perceptual scoring of phonetic errors rates in 100 word test. The results of the initial evaluation served as primary guidlines for the indivisualized treatment planning of each patient's speech problems. After mean treatment period of 5 months, the follow-up data of both dysarthric groups showed increased maximum phonation time, increased alternative motion rate and decreased occurrence of articulatory deviation. The changes of acoustic data and therapeutic effects were more prominent in children with dysarthria due to neurologic causes than with functional dysarthria. Three cases including their pre- and post treatment data were illustrated in detail.

• 한방안이비인후피부과학회지
• /
• 제21권1호
• /
• pp.26-37
• /
• 2008

Objective : The present study was carried out to investigate the effects of NaisoOkseol-Tang (NOT) on solid tumor in mice in terms of immune-potentiating and direct cytotoxic action of NOT in vitro and vivo study. Methods: The present author investigated thymocyte proliferation and NO production to confirm immune-potentiating activity of NOT and also investigated body/tumor weight and survival rates in tumor bearing mice. In this study, administration of NOT decreased tumor/weight ratio significantly, and prolonged survival duration compared to non-treated control. Treatment with NOT also elevated proliferation rates of thymocytes isolated from tumor bearing mice. Results: In vitro study, treatment with NOT suppressed proliferation rate of Sarcoma 180 (S-180) cells. Contrary, treatment with NOT elevated proliferation rate of thymocytes. These results were co-related with in vivo study. In addition, NO production from abdominal macrophages isolated from normal mice was not affected by treatment with NOT. Conclusion : NOT is useful to treat patient with solid tumor, because NOT has direct toxic action for tumor cell and immune-potentiating action for T cells.

• 대한방사선기술학회지:방사선기술과학
• /
• 제45권1호
• /
• pp.31-39
• /
• 2022

This study aimed to analyze educational understanding and satisfaction by survey including for the online educational videos by used online platform (YouTube) which provide resolve patient's questions, require attention and treatment information for a patient with radiation therapy. Video viewing analysis was used by YouTube studio. The survey was analyzed general properties (age, academic ability, disease, and watched of no watched videos) and educational understanding and satisfaction for two groups as no watched and watched patients. The views number was 60% at the female higher than 40% at the male. Based on the standard viewing time (hours), the non-subscription rate was 86.7%. The device type mostly used the mobile phone (82.8%). The viewership of educational videos was lower as the age increased and the academic ability decreased in the survey. The educational understanding increased by 22% at watched group as 4.15 point from at no watched group as 3.4 point (p<0.001), and the educational satisfaction increased by 15.8% at watched group as 4.25 point from at no watched group as 3.67 point (p<0.01). The correlation of understanding (r=0.761) and satisfaction (r=0.767) was high for both no watched and watched groups (p<0.01). The online educational videos increased educational understanding and satisfaction for the patient with radiation therapy. Our study could be used references data for improving the quality of medical services.

• 한방안이비인후피부과학회지
• /
• 제22권3호
• /
• pp.178-187
• /
• 2009

5개월 동안 외래를 통해 꾸준한 약물치료 및 외치요법을 실시하여 호전되던 중 재발한 중증의 아토피피부염 소아환자에게 10일간의 단기입원치료를 통하여 약물치료 뿐만 아니라 한약 외용제,습포제 및 기타 치료 및 교육을 적극적으로 실시한 결과 객관적인 SCORAD score 및 주관적인 평가에서 긍정적인 변화가 있었음을 확인할 수 있었다. 한 명의 동일한 환자에게 증상의 정도가 비슷한 상태에서 외래와 입원이라는 방법으로 똑같은 치료를 수행했을 때, 다른 결과가 나왔는데 이는 집에서 자가적 치료가 원활하게 이루어지지 않았기 때문으로 생각되며, 단기입원을 통한 아토피피부염 치료는 외래치료의 한계를 극복하는 대안이 될 수 있을 것으로 기대된다.

• Asian Pacific Journal of Cancer Prevention
• /
• 제16권18호
• /
• pp.8321-8325
• /
• 2016

Background: The incidence of hydatidiform mole (HM) differs among regions but has declined significantly over time. In Thailand, the initiation of universal health coverage in 2002 has resulted in a change of medical services countrywide. However, impacts of these policies on gestational trophoblastic disease (GTD) cases in Thailand have not been reported. This study aimed to find the incidence of hydatidiform mole (HM) in King Chulalongkorn Memorial Hospital (KCMH) from 1994-2013, comparing before and after the implementation of the universal coverage health policy. Materials and Methods: All cases of GTD in KCMH from 1994-2013 were reviewed from medical records. The incidence of HM, patient characteristics, treatment and remission rates were compared over two study decades between 1994-2003 and 2004-2013. Results: Hydatidiform mole cases decreased from 204 cases in the first decade to 111 cases in the seond decade. Overall incidence of HM was 1.70 per 1,000 deliveries. The incidence of HM in the first and second decades were 1.70 and 1.71 per 1,000 deliveries, respectively (p=0.65, 95%CI 1.54-1.88). Referred cases of nonmolar gestational trophoblastic neoplasia (GTN) increased from 12 (4.4%) to 23 (14.4%, p<0.01). Vaginal bleeding was the most common presenting symptom which decreased from 89.4% to 79.6% (p=0.02). Asymptomatic HM patients increased from 4.8% to 10.2% (p=0.07). Rate of postmolar GTN was 26%. Conclusions: The number of HM cases in this study decreased over 2 decades but incidence was unchanged. Referral rates of malignant cases were more common after universal health coverage policy initiation. Classic clinical presentation was decreased significantly in the last decade.

• 여성건강간호학회지
• /
• 제8권2호
• /
• pp.151-164
• /
• 2002

PURPOSE: Estrogen replacement therapy is indicated for the relief of hot flushes and urogenital atrophy, the prevention of osteoporosis and the reduction in risk of cardiovascular disease. The present study assessed by blood pressure, heart rate variability, and climacteric symptoms in menopausal women before treatment and at 1 month during estrogen replacement therapy. METHODS: The study sample consisted of 16 healthy menopausal women (range 49 to 59 years, mean : 53.4 years) attending menopausal clinics for the complaint of climateric symptoms at S. hospital in Chunchoen. They were all non-smokers and no patient had symptoms or evidence of cardiovascular disease. They took estrogen replacement therapy (conjugated estrogen 0.625 mg with or without medroxy progesteron 2.5mg) for 1 month. Blood pressure, heart rate variability(heart period and vagal tone) through ECG, and climacteric symptom were measured in all subjects before treatment and at 1 month during treatment. Climacteric symptom questionnaire which was developed by Neugarten et al.(1963) was modified with 20 items of question(Cronbach's alpha = 88 -.89). The data was collected from Sept. 1. 2000 to July. 30. 2001. RESULTS: There was no significant difference in mean systolic and diastolic pressure between the baseline and at 1 month during treatment. The mean heart period and vagal tone were slightly increased, but difference of mean heart period and vagal tone were not statistically significant between the baseline and at 1 month during treatment. The score of climacteric symptoms decreased significantly from the baseline after treatment. CONCLUSIONS: Even though, this study did not show that estrogen replacement therapy led decrease of blood pressure and increase heart rate variability, climacteric symptoms reduced much in all subjects after taking drugs. These results suggest that there is need to repeat study with long term period.

• 한국식품영양과학회지
• /
• 제32권8호
• /
• pp.1357-1363
• /
• 2003

면역 물질인 IgY가 함유된 다기능성 계란 섭취로 인체에서 H. priori제균 치료에 어떠한 효과를 나타내는지 알아보고자 H. pylori 양성인 위염 환자 63명을 대상으로 임의로 IgY 함유 계란 투여군(17명), 항생제 투여군(17명) 및 항생제와 IgY 함유 계란 병합투여군(16명)으로 나누고 2주간 치료하였고 IgY 정제 투여군(13명)은 1개월간 치료하였다. 치료후 H. pylori 박멸률, $^{13}$$CO_2$ 변화율($\Delta$$^{13}$$CO_2$) 및 updated sydney system에 따른 H. pylori 균체 밀도, 급만성 염증 활성도, 장상피화생을 비롯한 위축도등의 조직학적 변화에 대한 시험결과는 다음과 같다. IgY 함유 계란 투여군, 항생제 투여군, 항생제와 IgY 함유 계란 병합투여군 및 IgY 정제 투여군에서 H. pylori 박멸률은 각각 0%, 88%, 94% 및 0%로 IgY 함유 계란을 항생제와 병합투여 했을 때 항생제만 투여할 때 보다 H. pylori 박멸률이 높게 나타났지만 유의성은 없었다. IgY함유 계란 투여군 17명중 1명이 $\Delta$$^{13}$$CO_2$이 감소하는 경향을 보였지만 나머지는 변함이 없었다. 항생제와 IgY 함유 계란 병합투여군 16명중 15명에서 치료 1주째 $\Delta$$^{13}$$CO_2$이 모두 4이하로 치료전보다 유의하게 감소하였으며 (p<0.05), 나머지 1명도 치료 1주와 2주째 $\Delta$$^{13}$$CO_2$이 치료 전에 비해 감소하는 경향을 보였다. IgY 함유 계란 투여군과 IgY 정제 투여군에서 위전정부의 급성 염증 활성도가 유의하게 감소하였다 (p<0.01). IgY 함유 계란 투여군과 IgY 정제 투여군에서 위전정부의 H pylori 균체 밀도가 유의하게 감소하였다 (p<0.05). IgY정제 투여군에서 위체부의 만성 염증 활성도가 감소하는 경항을 보였다. IgY 함유 계란 투여군에서 위전정부 및 위체부의 장상피화생과 위축도는 치료전후 변화가 없었다. IgY정제 투여군의 1예에서만 치료전 위전정부에 경도의 장상피화생이 관찰되었으며 치료후 정상으로 호전되었다. 위점막 위축은 대상환자 모두에서 치료전후 변화가 없었다.

• Archives of Plastic Surgery
• /
• 제36권6호
• /
• pp.727-734
• /
• 2009

Purpose: The Inaba's procedure, the treatment of osmidrosis axillae, has the advantages of low recurrent rate and easy to learn, yet it produces early postoperative discomfort and scar formation by tie - over dressing. The authors modified the Inaba's procedure by using delayed suture of the incision wound and omitting tie - over dressing. The comparative study of Inaba's procedure and its modification was performed to confirm the advantages of modified procedure. Methods: The study contains the retrospective analysis of the medical records of 296 patients with osmidrosis who were treated using the Inaba's procedure from December, 1996 to February, 2007. The study also contains the prospective analysis of 20 patients, from March, 2007 to July, 2008, who were treated by the modified Inaba's procedure with delayed suture of the incision wound and gentle pressure dressing instead of tie - over dressing. The operative results of two groups were compared and verified by Mann - Whitney U test(SPSS 12.0). Results: The incidence of complications was 14.5% in the Inaba's procedure, whereas 6.2% in the modified Inaba's procedure. Both procedures have the same basic surgical procedure in terms of the location of incision site and subdermal shaving of the sweat glands, and therefore similar good results were obtained in the aspect of postoperative axillary odor, recurrent rate and postoperative condition of axillary hair. Certainly, the modified Inaba's procedure had better outcome in each element of PSS(Patient Scar Self-Rating Scale), compared to the Inaba's procedure. In addition, the modified Inaba's procedure showed a statistical significance in dressing - related pain reduction and overall satisfaction. Conclusion: The modified Inaba's procedure had advantages of decreased early postoperative complications such as hematoma, discomfort and pain caused by tie - over dressing, and decreased scar formation. However, the drawback was delayed suture of the incision wound after 48 hours.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
• /
• 제35권5호
• /
• pp.304-309
• /
• 2009

Purpose: Fibrous dysplasia (FD) is a fibro-osseous disease associated with activating missense mutations of the gene encoding the $\alpha$-subunit of stimulatory G protein. FD may affect a single bone (called monostotic form) or multiple bones (called polyostotic form). The extent of lesions reflects the onset time of mutation. In this study, cells from monostotic FD in maxilla of a patient were isolated and cultured in vitro for characterization. Materials and Methods: The single cells were released from FD lesion which was surgical specimen from 15 years-old boy. These isolated cells were cultured in vitro and tested their proliferation activity with MTT assay. In osteogenic media, these cells underwent differentiation process comparing with its normal counterpart i.e. bone marrow stromal cells. The proliferated FD cells were detached and transplanted into the dordsal pocket of nude mouse and harvested in 6 weeks and 12 weeks. Results and Summary: FD cells have an increased proliferation rate and poor differentiation. As a result, cells isolated from FD lesion decreased differentiation into osteoblast and increased proliferation capacity. MTT assay presented that proliferation rate of FD cells were higher than control. However, the mineral induction capacity of FD was lesser than that of control. Monostotic FD cells make fewer amounts of bone ossicles and most of them are woven bone rather than lamellar bone in vivo transplantation. In transplanted FD cells, hematopoietic marrow were not seen in the marrow space and filled with the organized fibrous tissue. Therefore, they were recapitulated to the original histological features of FD lesion. Collectively, these results indicated that the FD cells were shown that the increased proliferation and decreased differentiation potential. These in vitro and in vivo system can be useful to test FD cell's fate and possible.