• YAKHAK HOEJI
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• v.45 no.3
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• pp.276-281
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• 2001

The present study was conducted to evaluate the effect of KST221085, a newly synthesized antidiabetic agent, on the hearts from streptozotocin (STZ)-induced diabetic rats. In isolated diabetic hearts, left ventricular developed pressure (LVDP), heart rate (HR) and coronary flow rate (CFR) were decreased compared to normal control, indicating cardiovascular dysfunction in diabetic heart. The treatment with 10 $\mu$M KST221085 remarkably improved the diabetes-induced contractile impairment, without any influence on HR. Reduced coronary flow in diabetic heart was also significantly increased by treatment with 10 $\mu$M KST221085. In isolated aorta from diabetic rat, treatment with 10 $\mu$M KST221085 increased endothelium-dependent relaxation, suggesting that KST221085 can improve the impaired endothelial function in diabetic aorta. Our results suggest that KST221085 treatment can improve the cardiovascular dysfunction in STZ-induced diabetic rats.

• Bulletin of the Korean Chemical Society
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• v.35 no.1
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• pp.151-157
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• 2014

We have reported the reaction probability, integral reaction cross section, and rate constant for the title system calculated with the aid of a time-dependent wave packet approach. The ab initio potential energy surface (PES) of Prudente et al. (Chem. Phys. Lett. 2009, 474, 18) is employed for the purpose. The calculations are carried out over the collision energy range of 0.05-1.4 eV for the two reaction channels of H + LiH ${\rightarrow}$ Li + $H_2$ and $H_b$ + $LiH_a$ ${\rightarrow}$ $LiH_b$ + $H_a$. The Coriolis coupling (CC) effect are taken into account. The importance of including the Coriolis coupling quantum scattering calculations are revealed by the comparison between the Coriolis coupling and the centrifugal sudden (CS) approximation calculations.

• 연구논문집
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• s.30
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• pp.93-99
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• 2000

Electro-Rheological(ER) fluids change their apparent viscosity according to the electric field strength. The electrical and rheological properties of zeolite based the ER fluids were reported. The electric field dependent yield stress are obtained from experimental investigation on the Bingham property of the ER fluid. Using ER fluids, it is possible to directly interface between electric drop and flow rate of the ER fluid was hydraulic control valve measured under application of an electric field. The purpose of the present study is pressure drop measurement of an ER valve by using strain gage. The performance characteristics of the valve system are evalusted in terms of pressrue fixed with respect to the intensity of employed electric fields and flow rates. As a result, it is esperimentally confirmed that pressure control valve using ER fluids applicable to use in hydraulic power systems.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2009.05a
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• pp.450-453
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• 2009

In order to overcome drawbacks of the advanced high strength steel such as inferior formability and large springback, the hot press forming process(HPF) has been being applied for forming of automotive sheet parts. Good formability and dimensional accuracy without springback as well as good crash performance of final products are the advantages of the HPF process. In this work, a method to characterize the mechanical properties of the HPF steel was developed based on the simple tension test at high temperatures and its finite element analysis, while it was applied to obtain strain rate and temperature dependent flow curves of the HPF steel. The final flow curves were represented by utilizing the Johnson-Cook type equation both in uniform and post-uniform deformation regions.

• Bulletin of the Korean Chemical Society
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• v.25 no.12
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• pp.1907-1910
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• 2004

Generation of hydroxyl radical, one of their major active species in ozonation of water was directly observed with spin-trapping/electron spin resonance (ESR) technique using 5,5-dimethyl-pyrrolidine-1-oxyl (DMPO) as a spin-trapping reagent. Hydroxyl radical was trapped with DMPO as a stable radical, DMPO-OH. 80 mM of ozone produced $1.08{\times}10^{-6}$M of DMPO-OH, indicating that 1.4% of ${\cdot}$OH is trapped with DMPO if ${\cdot}$OH is produced stoichiometrically from ozone. Humic acid suppressed DMPO-OH generation in a dose-dependent manner. Generation rate of DMPO-OH was determined with ESR/stopped-flow measurement. Phenol derivatives increased the amount and generation rate of DMPO-OH, indicating that phenol derivatives enhance·OH generation during ozonation of water.

• International Journal of Reliability and Applications
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• v.2 no.4
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• pp.241-251
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• 2001

In this paper, optimal bum-in time to minimize the total mean cost, which is the sum of manufacturing cost with burn-in and cumulative warranty-related cost, is obtained. When the products with cumulative pro-rata warranty have high failure rate in the early period (infant mortality period), a burn-in procedure is adopted to eliminate early product failures. After burn-in, the posterior product life distribution and the warranty-related cost are dependent on burn-in time; long burn-in period may reduce the warranty-related cost, but it increases the manufacturing cost. The paper provides a methodology to obtain total mean cost under burn-in and cumulative pro-rata warranty. Property of the optimal burn-in time is analyzed, and numerical examples and sensitivity analysis are studied.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.10 no.3
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• pp.358-367
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• 1998

Since the performance of cooling tower is strongly dependent on the thermal performance of the packing, the evaluations of heat transfer rate and fan power from various packing have attracted intense interest. In the present study, two new packings have been devised and their performances have been compared with those of two existing packings to find better shape characteristic. It is found that one of the existing packings, which showed high heat transfer rate and medium fan power due to zig -zag flow passages and highly irregular surfaces, should be adapted.

• Proceedings of the Korean Society Of Semiconductor Equipment Technology
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• 2003.12a
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• pp.192-199
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• 2003

Film growth of InP and GaAs using TMIn, TMGa, TBAs and TBP is numerically predicted and compared to the experimental results. To obtain exact thermal boundary conditions at the reactor walls, the gas flow and heat transfer are analyzed for full three-dimensional reactor including outer tube as well as the inner reactor parts. The results indicate that the exact thermal boundary conditions are important to get precise film growth rate prediction since film deposition is mainly controlled by the temperature dependent diffusion. The results also show that thermal diffusion plays an important role in the upstream region.

• Bulletin of the Korean Chemical Society
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• v.27 no.1
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• pp.71-76
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• 2006

Porous polymer monolithic columns were prepared by the direct free radical copolymerization of methacrylic acid and ethylene glycol dimethacrylate within the confines of a chromatographic column in the presence of toluene-dodecanol as a porogenic solvent. The separation characteristics of the monolithic columns were tested by a homologous series of xanthine derivatives, theophylline and caffeine. The effects of the polymerization mixture composition and polymerization condition, mobile phase composition, flow rate and temperature on the retention times and separation efficiencies were investigated. The results showed that the selection of correct porogenic solvents and appropriate polymerization conditions are crucial for the preparation of the monolithic stationary phases. The separation efficiency was only extremely weakly dependent on flow rate and temperatures. Hydrogen-bonding interaction played an important role in the retention and separation. Compared with conventional particle columns, the monolithic column exhibited good stability, ease of regeneration, high separation efficiency and fast analysis.

• Structural Engineering and Mechanics
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• v.23 no.2
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• pp.163-175
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• 2006

In this paper, the dynamic response of a piezoelectric layer with a penny-shaped crack is investigated. The piezoelectric layer is subjected to an axisymmetrical action of both mechanical and electrical impacts. Two kinds of crack surface conditions, i.e., electrically impermeable and electrically permeable, are adopted. Based upon integral transform technique, the crack boundary value problem is reduced to a system of Fredholm integral equations in the Laplace transform domain. By making use of numerical Laplace inversion the time-dependent dynamic stress and electric displacement intensity factors are obtained, and the dynamic energy release rate is further derived. Numerical results are plotted to show the effects of both the piezoelectric layer thickness and the electrical impact loadings on the dynamic fracture behaviors of the crack tips.