• Title/Summary/Keyword: rate dependent

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Synchronization Phenomenon of Imports & Exports Trade Volume, Imports & Exports Amount, Trade Balance of ICT (ICT 산업의 수출입 물동량과 수출입액, 무역수지의 동조화현상)

  • Choi, Jeong-Il
    • Journal of Convergence for Information Technology
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    • v.10 no.5
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    • pp.92-100
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    • 2020
  • The purpose of this study is to analyze the relationship between export weight, import weight, export amount, import amount, and trade balance of ICT industry. The data used were gathered from the Korea Customs Service trade statistics. The analysis period used annual data for 19 years from 2000 to 2018. The change rate analysis was shown in order of trade balance, export amount, import amount, import weight and export weight. The increase rate analysis showed that the trade balance was the highest at 919%.. In the correlation analysis, the trade balance and export amount were 0.95, showing the highest correlation coefficient. As a result of the regression analysis, the export amount for the trade balance, the dependent variable, was Coefficient 2.37, which was positive(+). Each variable is changing independently of one another. Since 2000, the trade balance of the Korean ICT industry has led 84% of Korea's total trade balance. In the future, Korea's ICT industry should be further developed for Korea's economic development, and exports should be further increased to increase the trade balance. In the next paper, we will try to find a field that can be specifically developed by subdividing the ICT industry.

Induction of Selective Cell Death of Oral Squamous Carcinoma Cells by Integrin α2 Antibody and EGFR Antibody (인테그린 α2와 상피성장인자수용체 차단항체의 저해작용을 통한 구강편평상피암 세포의 선택적 제거)

  • Choi, Yeon-Sik;Kim, Gyoo-Cheon;Yoon, Sik;Hwang, Dae-Seok;Kim, Cheol-Hun;Jeon, Young-Chan;Byun, June-Ho;Shin, Sang-Hun;Kim, Uk-Kyu
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.35 no.3
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    • pp.143-154
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    • 2013
  • Purpose: This study was to find efficacy of integrin alpha2 (${\alpha}_2$) and epidermal growth factor receptor (EGFR) as tumor marker of oral squamous cell carcinoma (SCC) and clarify the selective cell death effect of anti-integrin ${\alpha}_2$ and anti-EGFR on SCC cells, additionally testify conjugated gold nanoparticles (GNP) with air plasma for selective cell death of oral SCC. Methods: Expression of integrin ${\alpha}_2$, EGFR on human SCC cells (SCC25) were examined by western blot. SCC25 cells were treated with anti-integrin ${\alpha}_2$, anti-EGFR and analysed by Hemacolor staining, immunoflorescence staining, FACS flow cytometry. Conjugated GNP with integrin ${\alpha}_2$, EGFR antibody were treated by air plasma on SCC cells. Results: Integrin ${\alpha}_2$ and EGFR were over-expressed on SCC25 cells than normal lung WI-38 cells. The cell viability rate of SCC25 cells treated with anti-integrin ${\alpha}_2$, anti-EGFR was lower than WI-38 cells. The concentration changes of nucleus, releasing cytochrome c and apoptosis inducing factor (AIF) from mitochondria to cytosol were observed. The changes of proteins related with apoptosis were observed. Increase of bax, bcl-xL, activation of caspase-3, -7, -9, and fragmentation of PARP, DFF45 and decrease of lamin A/C in SCC25 cells were observed. In FACS, increase of sub-$G_1$ and S phase was observed. Cell cycle related proteins, Such as cyclin D1, cyclin dependent kinase (CDK) 4, cyclin A, cyclin E, CDK 2, p27 were decreased. After SCC25 cells treated with conjugatged GNP-Integrin ${\alpha}_2$, GNP-EGFR, additionally air plasma, the cell death rate was significantly increased. Conclusion: Integrin ${\alpha}_2$, EGFR were over-expressed in oral SCC cells. Anti-integrin ${\alpha}_2$, anti-EGFR in SCC25 cells induced apoptosis selectively. When GNP-anti integrin ${\alpha}_2$, GNP-anti EGFR were treated with air plasma on SCC25 cells, cancer cells were died more selectively. GNP-anti integrin ${\alpha}_2$, GNP-anti EGFR with air plasma could be treatment choice of oral SCC.

The Effects of Policy Funds for Small and Medium Enterprises (중소기업 정책자금 지원이 중소.벤처기업 재무성과에 미치는 영향 - 중소기업진흥공단 정책자금 지원을 중심으로 -)

  • Chae, Kwang-Ki;Yoon, Byung-Seop;Ha, Kyu-Soo
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.6 no.3
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    • pp.85-107
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    • 2011
  • This study analyzed the influence of supporting policy fund on financial performance of small & medium sized venture firms. The outcomes are as follows. First, it was found that 11 dependent variables in profitability, stability, activity, and growth represent have significantly positive influence on financial performances 4 years after policy fund rather than prior to the fund. In short, supporting policy fund is found to bring improvement on financial performance. Second, it was found that growth rate in asset as a growth indicator and interest coverage ratio as a stability indicator have significantly positive influence on operating income to sales and ROA, respectively. Third, it was found that operating income to sales as a profitability indicator and asset turnover ratio as an activity indicator have positive influence on current ratio. Finally operating income to sales as a profitability indicator and growth rate in sales as a growth indicator have positive influence on interest coverage ratio.

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Characteristics of Cyanide Decomposition by Hydrogen Peroxide Reduction (과산화수소에 의한 시안의 분해특성)

  • 이진영;윤호성;김철주;김성돈;김준수
    • Resources Recycling
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    • v.11 no.2
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    • pp.3-13
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    • 2002
  • The characteristics of cyanide decomposition in aqueous phase by hydrogen peroxide have been explored in an effort to develop a process to recycle waste water. The self-decomposition of $H_2O$$_2$at pH 10 or below was minimal even in 90 min., with keeping about 90% of $H_2O$$_2$undissociated. On the contrary, at pH 12 only 9% of it remained during the same time. In the presence of copper catalyst at 5 g Cu/L, complete decomposition of $H_2$O$_2$was accomplished at pH 12 even in a shorter time of 40 min. The volatility of free cyanide was decisively dependent on the solution pH: the majority of free cyanide was volatilized at pH 8 or below, however, only 10% of it was volatilized at pH 10 or above. In non-catalytic cyanide decomposition, the free cyanide removal was incomplete in 300 min. even in an excessive addition of $H_2$$O_2$at a $H_2$$O_2$/CN molar ratio of 4, with leaving behind about 8% of free cyanide. On the other hand, in the presence of copper catalyst at a Cu/CN molar ratio of 0.2, the free cyanide was mostly decomposed in only 16 min. at a reducedH202/CN molar ratio of 2. Ihe efnciency of HBO2 in cyanide decomposition decreased with increasing addition of H2O2 since the seu-decomposition rate of $H_2$$O_2$increased. At the optimum $H_2$$O_2$/mo1ar ratio 0.2 of and Cu/CN molar ratio of 0.05, the free cyanide could be completely decomposed in 70 min., having a self-decomposition rate of 22 mM/min and a H$_2$$O_2$ efficiency of 57%.

A Trial to Develop Forecasting Model for Turn-out Rates with the 2010 Korean Gubernatorial Election Data (후보자 득표율 예측 모형과 지표의 구성: 2010 광역단체장 선거를 중심으로)

  • Song, Keun-Won
    • Survey Research
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    • v.12 no.1
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    • pp.31-63
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    • 2011
  • This study is to make an effective forecasting model for turn-out rates of the candidates with their visibilities, which are measured in their names on the media during the election period. I make a regressive model, with the data of 2010 gubernatorial election in Korea, where turn-out rate is dependent variable and each candidate's visibility, incumbency effect, local control party effect, corruption effect, strategy voting effect, restrain effect as a mid-term evaluation, and policy effect are independent variables. I got the model, T = -4.65 + 1.02V + 16.90 I + 16.78L - 9.12 R, where T is turn-out rate, V is candidate's visibility, I is incumbent effect, L is local control party effect, and R is restrain effect. This function can be used to predict turn-out rates of the candidates in the forthcoming gubernatorial election in Korea at a small outlay.

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Contribution Rate of Plant Parts to Dry Matter Yields in Winter Forage Crops (사료용 맥류의 맥종별 건물수량에 대한 식물체 부위별 기여도)

  • Kwon, Young-Up;Park, Hyoung-Ho;Baek, Seong-Bum;Park, Kwang-Geun;Kim, Jung-Gon;Lee, Jae-Eun;Seo, Jong-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.55 no.4
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    • pp.292-298
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    • 2010
  • This study aims to understand the contribution rate of plant parts on biomass in five winter forage crops including barley, wheat, oat, rye and triticale. In barley and oat, the major plant parts on dry matter yields were changed from culm to spike at 20 days after heading(DAH), but culm was very important part on biomass of rye, wheat and triticales until 30DAH. Wheat, rye and triticales showed same pattern in dry weight increase indicating that culm was main component of biomass from heading stage but spike became heavier after 30 DAR. Barley and oat were similar in dry weight increase where spike was the main components of biomass at 20 DAR. After heading stage the major biomass of most winter forage crops were dependent on the weight of culm and spike, while the contribution of leaves to plant biomass was lower as compared to culm and spike. Thus culm and spike were very important factors for improving the dry matter production of winter forage crops breeding and early maturing is also additively required under Korean climatic condition.

Sorption of ο-Cresol by Granular Activated Carbon (GAC) and Abiotic Transformation on GAC Surface (입상활성탄에 의한 오르토크레졸(ο-cresol)의 흡착과 비생물학적 변형)

  • 한인섭;김용환
    • Journal of Soil and Groundwater Environment
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    • v.9 no.1
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    • pp.87-94
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    • 2004
  • The effects of pretreatment of GAC and dissolved oxygen (DO) on the sorption capacity for ο-cresol were investigated using pretreated GAC under oxic and anoxic conditions. Virgin GAC was used with pretreated GACs by $O_2$, acid and base as sorbents. Sorption capacity of GAC was dependent on the oxygen conditions according to the pretreatment methods. Virgin GAC showed increased sorption capacity when DO was present in the solution, while $O_2$-pretreated GAC did not show any considerable capacity change. Acid- and base-pretreated GACs were relatively more influenced by presence of DO as compared with virgin GAC. Both acid and base-pretreated GACs showed a rapid sorption rate at the initial stage, but as contact time became longer the sorption was slower. Sorbed ο-cresol was extracted with micro-Soxhlet extraction apparatus using the GAC separated from the rate experiments. Within 1 hour both acid and base-pretreated GACs showed the decrease in extraction efficiencies under both oxic and anoxic conditions. After 1 hour such a trend (the increase as contact time was longer) was not observed and showed relatively constant efficiencies of 35∼50%. According to the results of this study $O_2$contacted with GAC before sorption as well as DO present in the solution during sorption could influence the GAC sorption capacity.

Inhibitory effect of Nymphoides indica extract on α-MSH induced melanin synthesis (어리연꽃 추출물이 α-MSH 유도에 의한 멜라닌 생성 억제에 미치는 영향)

  • Kim, Dong-Hee;Kim, You-Ah;Yu, Jae-Myo;Park, Chae-Bin;Park, Byoung-Jun;Park, Tae-Soon
    • Journal of Applied Biological Chemistry
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    • v.60 no.4
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    • pp.327-332
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    • 2017
  • In this study, the whitening activity of Nymphoides indica extract in B16F10 cells were measured. Inhibition rate of tyrosinase from mushroom was 42% at $1,000{\mu}g/mL$. And inhibition of tyrosinase and melanin biosynthesis in B16F10 cells were 26 and 25% at $5{\mu}g/mL$, respectively. The expression levels of cAMP and protein kinase A (PKA), which are higher levels of melanin-related factors, were found to be decreased in a dose-dependent manner. In addition, the expression rate of protein and mRNA of tyrosinase, tyrosinase related protein 1 (TRP1), tyrosinase related protein 2 (TRP2) and microphthalmia associated transcription factor (MITF). In this study, it was confirmed that the N. indica extract effectively inhibited the activity of tyrosinase, TRP1, TRP2 and MITF as well as the activity of PKA by effectively inhibiting cAMP. Therefore, it was confirmed that the N. indica extract has high value as a functional material.

Gastrointestinal and Hepatic First-pass Effects of Triflusal in Rats (흰쥐에서 트리플루살의 위장관 및 간 초회통과효과)

  • Cho, Hea-Young;Jeong, Tae-Jin;Lee, Yong-Bok
    • Journal of Pharmaceutical Investigation
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    • v.31 no.4
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    • pp.265-271
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    • 2001
  • In order to elucidate the influence of intestinal and hepatic first-pass effect on the pharmacokinetics of triflusal, the biotransformation of triflusal in the gastrointestinal tract and liver was designed. Moreover, we tried to establish an HPLC method applicable for bioassay and available to pharmacokinetics, not only with the simultaneous determination of triflusal and its active metabolite, 2-hydroxy-4-trifluoromethyl benzoic acid (HTB), but also with improving sensitivity. After the administration of triflusal (10 mg/kg) and HTB (10 mg/kg) into femoral vein, portal vein (only triflusal) and oral route (only triflusal), pharmacokinetic parameters were investigated from the plasma concentration-time profiles of triflusal and HTB in rats. An HPLC method was developed for the simultaneous determination of triflusal and HTB in rat plasma, urine and bile. The HPLC analysis was carried out using a C18 column and acetonitrile-methanol-water (25:10:65, v/v/v) as the mobile phase and UV detection at 234 nm. Furosemide was used as the internal standard. The calibration curves were linear over the concentration range $0.05-5.0\;{\mu}g/ml$ for triflusal and $0.2-200.0\;{\mu}g/ml$ for HTB with correlation coefficients greater than 0.999 and with intra-day or inter-day coefficients of variation not exceeding 10.0%. This assay procedure was applied to the study of metabolite pharmacokinetics of triflusal and HTB in rats. It was supposed that triflusal was almost metabolized in vivo because urinary and biliary excreted amounts of triflusal could be ignored as it was lower than 1.2% of the administered dose. According to the gastrointestinal and hepatic biotransformation pathways of triflusal, it was found that triflusal was hydrolyzed by about 5% in intestine and metabolized by about 53% in liver, and that the bioavailability of triflusal after oral administration of triflusal was 0.44, and also that the fraction of total elimination rate of triflusal which formed HTB in liver $(F_{mi},\;%)$ was about 98%. These results showed that triflusal was almost metabolized in liver, and the total elimination of triflusal in the body was dependent to the formation rate of HTB from triflusal in liver.

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CO2 Emission and Productivity of Fossil-fueled Power Plants: A Luenberger Indicator Approach (CO2 배출량을 감안한 화력발전소의 생산성 변화 분석: Luenberger지수 접근법)

  • Kwon, Oh-Sang
    • Environmental and Resource Economics Review
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    • v.19 no.4
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    • pp.733-752
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    • 2010
  • This study applies the Luenberger indicator approach to estimate productivity of the Korean fossil-fueled power plants. A panel data set of 25 power plants was used. The method incorporates $CO_2$ emission as an undesirable output and shows that ignoring $CO_2$ emission overestimates the productivity change. There are two sources of overestimation. First, the usual method estimates productivity change ignoring the increase in $CO_2$ emission that occurred during the study period. Second, the productivity change estimated by the usual method that does not incorporate $CO_2$ emission is very sensitively affected by the change in operation rate. The paper decomposes the productivity change into the efficiency change and the technical change. The results show that the two sources contribute to the productivity change almost equally. It is also shown that the size and the pattern of productivity change are dependent on the plants' fuel types. Non-LNG power plants which saved their energy consumption and thereby reduced their $CO_2$ emission have achieved relatively high rate of productivity improvement.

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