• Journal of KIISE:Software and Applications
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• v.37 no.9
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• pp.706-711
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• 2010

In the applications of a human speech interface, reducing the error rate in recognition is the one of the main research issues. Many previous studies attempted to correct errors using post-processing, which is dependent on a manually constructed corpus and correction patterns. We propose an automatically learnable post-processing method that is independent of the characteristics of both the domain and the speech recognizer. We divide the entire post-processing task into two steps: error detection and error correction. We consider the error detection step as a classification problem for which we apply the conditional random fields (CRFs) classifier. Furthermore, we apply transformation-based learning (TBL) to the error correction step. Our experimental results indicate that the proposed method corrects a speech recognizer's insertion, deletion, and substitution errors by 25.85%, 3.57%, and 7.42%, respectively.

• Journal of Nutrition and Health
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• v.11 no.3
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• pp.25-30
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• 1978

A study was planned to evaluate the influence of continual heating at $150{\pm}5^{\circ}C$ and $170{\pm}5^{\circ}C$ respectively upon edible oils for frying the several food. Two kinds of domestic edible oils (Sample A and B) were collected by random sampling from market and in order to estimate deterioration degrees at both temperatures previously mentioned, thiobarbituric acid (TBA) value, acid value (AV), peroxide value (POV) and carbonyl value (CV) were measured at intervals due to its optical density. Those values were examined and compared according to the temperatures and times, and it was concluded as follows: 1) TBA value was rapidly increased until 24 hours in both temperatures and after 1 day its value have shown a slower increase as compared with initial rapid reaction. 2) Acid value and peroxide value of both oils (A & B) used for frying were increased continuously during heating and the changes in these values were dependent on the thermal oxidation, and moreover at low temperature $(150{\pm}5^{\circ}C)$ these values were found to be increased more readily than at high temperature $(170{\pm}5^{\circ}C)$. 3) Carbonyl value of both sample A and B show almost the same increasing rate at either $150{\pm}5^{\circ}C$ or $170{\pm}5^{\circ}C$ in proportion to the heating time. 4) It was found that there were differences between the chemical changes caused by heating sample A and B at high and low temperature.

• Journal of Nutrition and Health
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• v.25 no.6
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• pp.485-491
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• 1992

The effects of varying doses(1, 4 and 10mg/kg body weight/day) of testosterone propionate (TP) on body weight gain and composition and energy and muscle protein metabolism were investigated in female rats. TP had no effect on food intake at any dose but injection of 1mg/kg resulted in an in crease in body weight gain which was associated with increases in body protein and fat. At higher doses(4 and 10mg/kg) body protein content was still increased but body fat was not affected. Increases in energy gain and gross energetic efficiency were observed at a dose of 1mg/kg but neither parameter was affected at other doses. The mass protein and RNA content of gastrocnemius muscle were incerased by TPbut the ratio of RNA to protein and the rate of muscle protein synthesis measured in vivo were not affected at any dose of TP The results indicate that the effect of testosterne on body composition are highly dose-dependent and the anabolic action of testosterone is not through stimulation of protein synthesis.

• Structural Engineering and Mechanics
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• v.66 no.4
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• pp.505-513
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• 2018

Steam flooding is widely used in heavy oil reservoir with coupling effects among the formation temperature change, fluid flow and solid deformation. The effective stress, porosity and permeability in this process can be affected by the multi-physical coupling of thermal, hydraulic and mechanical processes (THM), resulting in a complex interaction of geomechanical effects and multiphase flow in the porous media. Quantification of the state of deformation and stress in the reservoir is therefore essential for the correct prediction of reservoir efficiency and productivity. This paper presents a coupled fluid flow, thermal and geomechanical model employing a program (MATLAB interface code), which was developed to couple conventional reservoir (ECLIPSE) and geomechanical (ABAQUS) simulators for coupled THM processes in multiphase reservoir modeling. In each simulation cycle, time dependent reservoir pressure and temperature fields obtained from three dimensional compositional reservoir models were transferred into finite element reservoir geomechanical models in ABAQUS as multi-phase flow in deforming reservoirs cannot be performed within ABAQUS and new porosity and permeability are obtained using volumetric strains for the next analysis step. Finally, the proposed approach is illustrated on a complex coupled problem related to steam flooding in an oil reservoir. The reservoir coupled study showed that permeability and porosity increase during the injection scenario and increasing rate around injection wells exceed those of other similar comparable cases. Also, during injection, the uplift occurred very fast just above the injection wells resulting in plastic deformation.

• Asian-Australasian Journal of Animal Sciences
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• v.20 no.5
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• pp.622-626
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• 2007

Using multi-trait animal model BLUP, selection was conducted over seven generations for growth rate (DG), real-time ultrasound loin-eye muscle area (LEA), backfat thickness (BF), and intramuscular fat content (IMF) to develop a new line of purebred Duroc pigs with enhanced meat production and meat quality. This study was intended to investigate the relationship between restriction fragment length polymorphism (RFLP) of a heart fatty acid-binding protein (H-FABP) gene and intramuscular fat content (IMF) of this Duroc purebred population. The present experiment examined the RFLP of 499 slaughtered pigs. The DNA was separated from the blood or ear tissue of the pigs, which were slaughtered at 105 kg of body weight. Intramuscular fat content of the longissimus muscle was measured using chemical analysis. A significant difference was detected in the breeding value of IMF among the H-FABP PCR RFLP genotypes. The AA genotype has a significantly larger positive effect on the IMF breeding value than do the Aa and aa genotypes for the MspI RFLP. In addition, the DD genotype has a significantly greater positive effect on IMF breeding value than the Dd and dd genotypes for the HaeIII RFLP. For the HinfI RFLP, the hh genotype has a significantly larger positive effect on IMF breeding value than the HH genotype. Multiple regression analysis was performed using the IMF breeding values as the dependent variable and the three H-FABP genotypes as independent variables. Results revealed that the contribution of the genotypes to variation in IMF breeding values was approximately 40%. These results demonstrated that H-FABP RFLPs affect IMF in this Duroc population.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.12
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• pp.4919-4923
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• 2014

Background: To investigate the effect of celecoxib on telomerase activity and apoptosis in a human laryngeal squamous carcinoma cell line (Hep-2 cells). Materials and Methods: The growth inhibition rate of Hep-2 cells in vitro was measured by MTT assay, and apoptosis by TUNEL assay and flow cytometry (FCM). The TRAP-ELISA method was used to determine telomerase activity in Hep-2 cells. The mRNA expression of human telomerase RNA component(hTR), human telomerase reverse transcriptase (hTERT) and human telomerase-associated protein(hTEP1) was determined by RT-PCR assay. Expression of Bax and Bcl-2 proteins was assessed by Western blotting. Results: Celecoxib can inhibit proliferation and induce apoptosis in a dose- and time-dependent manner, repress telomerase activity, decrease hTERT mRNA and Bcl-2 protein expression and increase Bax protein expression, PGE2 had no effect on telomerase. Conclusions: Celecoxib had the antiproliferative and pro-apoptotic effect in Hep-2 cells. Apoptosis was accompanied by a decrease in telomerase activity which was directly correlated with hTERT mRNA and up-regulation of Bax/Bcl-2. Bcl-2 may thus play an important role in telomerase activity as well as apoptosis.

• The Journal of the Acoustical Society of Korea
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• v.16 no.3
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• pp.64-72
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• 1997

In this paper, study and experiments are performed for finding recognition unit fit which can be used in large vocabulary recognition system. Specifically, a phoneme that is currently used as recognition unit and a syllable in which Korean is well characterized are selected. From comparisons of recognition experiments, the study is performed whether a syllable can be considered as recognition unit of Korean recognition system. For report of an objective result of the comparison experiment, we collected speech data of a male speaker and processed them by hand-segmentation for phoneme boundary and labeling to construct speech database. And for training and recognition based on HMM, we used HTK (HMM Tool Kit) 2.0 of commercial tool from Entropic Co. to experiment in same condition. We applied two HMM model topologies, 3 emitting state of 5 state and 6 emitting state of 8 state, in Continuous HMM on training of each recognition unit. We also used 3 sets of PBW (Phonetically Balanced Words) and 1 set of POW(Phonetically Optimized Words) for training and another 1 set of PBW for recognition, that is "Speaker Dependent Medium Vocabulary Size Recognition." Experiments result reports that recognition rate is 95.65% in phoneme unit, 94.41% in syllable unit and decoding time of recognition in syllable unit is faster by 25% than in phoneme.

• Journal of Korean Ophthalmic Optics Society
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• v.5 no.1
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• pp.49-53
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• 2000

Sodium borate silicate glass of composition $10Na_2O-39B_2O_3-50SiO_2-CoO$ and $20Na_2O-14B_2O_3-65SiO_2-CoO$ were prepared by melting oxide mixtures in alumina crucible at $1210^{\circ}C$ in an electric furance in air for 2h, and then quenching in air. The dielectric behavior of the quenched glasses are the subject of the present work. Properties such as dielectric constant and resistivity as a function frequency and temperature are reported. From the dielectric spectra, the glass phase transition temperature has been found to decrease at a rate $Na_2O$ 20 mol% and the dielectric constants increase with increasing $Na_2O$ content. The frequency dependent resistivity response of glass exhibits a non-Debye type relaxation.

• The Korean Journal of Pharmacology
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• v.27 no.2
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• pp.99-108
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• 1991

The effect of racemic Ketamine HCl was observed on excitable membranes of sciatic nerve fibres and toe muscles from frog. Ketamine significantly depressed the amplitude of the action potential, maximum rate of rise and that of fall of action potentials of sciatic nerve by dose-dependent and time-course manner, and also it produced the inhibition of $K^+-contracture$ in toe muscle. We used two different ways of sucrose gap method to to obtain the better results from sciatic nerve. We observed and compared the effect of ketamine on sciatic nerve with naloxone, 4-AP (4-aminopyridine) and TEA (Tetraethylammonium). Naloxone significantly but not totally blocked the effect of ketamine both on nerve and on skeletal muscle. 4-AP or TEA by itself had a significant depressant effect on the action potentials on nerve by central perfusion (extracellular perfusion), but both of these drugs did not much affect the action of Ketamine on nerve. The reversibility of effect of Ketamine (10 mM) was observed both on nerve and on skeletal muscles when exposed to drug for short duration. The effects of racemic ketamine described may provide to support that one of the mechanisms of the action of Ketamine on nerve and on muscles of frog might be related to non-specifically effect on receptors within the ion channels $(K^+-channel,\;Na^+-channel\;or\;slow\;Ca^{++}\;channel)$ at higher dose which produces anesthetic effect and also it interacts specifically with one of the opioid receptors or subtype of these receptors which is sensitive to Naloxone at lower dose which produces analgesia.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.3
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• pp.249-254
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• 2014

The purpose of this study is to characterize the effects of KHG26792 (3-(naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride), a potential skin whitening agent, on melanin synthesis and identify the underlying mechanism of action. Our data showed that KHG26792 significantly reduced melanin synthesis in a dose-dependent manner. Additionally, KHG26792 downregulated microphthalmia-associated transcription factor (MITF) and tyrosinase, the rate-limiting enzyme in melanogenesis, although tyrosinase was not inhibited directly. KHG26792 activated extracellular signal-regulated kinase (ERK), whereas an ERK pathway inhibitor, PD98059, rescued KHG26792-induced hypopigmentation. These results suggest that KHG26792 decreases melanin production via ERK activation. Moreover, the hypopigmentary effects of KHG26792 were confirmed in a pigmented skin equivalent model using Cervi cornus Colla (deer antler glue), in which the color of the pigmented artificial skin became lighter after treatment with KHG26792. In summary, our findings suggest that KHG26792 is a novel skin whitening agent.