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Metal-Organic Vapor Phase Epitaxy IV. MOVPE and ALE Reaction Mechanisms (MOVPE 단결정층 성장법 IV. MOVPE 및 ALE 반응경로)

  • 정원국
    • Journal of Surface Science and Engineering
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    • v.24 no.1
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    • pp.1-17
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    • 1991
  • Understanding of the detailed reaction mechanisms during MOVPE and ALE is essential to further improve the properties of the grown crystals and the controllability of the growth parameters. The unified models for the detailed reaction paths are not available at this stage. The study, however, has been advanced to the extent that consensus on some of the reaction paths can be drawn from the scattered data. Metalakyls such as TMGa and TMIn seem to nearly fully decompose in the gas phase through homogeneous reaction at the typical MOVPE growth temperature. Hydrides such as AsH3 and PH3, on the contrary. seem to decompose heterogeneously onthe substrate surfaces as well as homogeneously in the gas phase. However, at lower temperatures, where ALE crystals are typically grown, the growth process is strongly dependent on the surface reactions. It seems that steric hindrance effects which the radicals reaching the substrate exhibit on the surface the growth rate a function of the metalalkyle supply durations. In addition, dydrogens released from hydrides seem to play an essential role in removing carbons leberated from the metalalkyls. High growth temperatures also seem to be effective in desorbing carbons from surface. The understanding of the reaction mechanisms was possible though diverse appraaches utilizing many ex-situ and in-situ diagnostic techniques and genuine experimental designs. It is the purpose of this paper to review and discuss many of these efforts and to draw some possible conclusions from them.

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Metal-Organic Vapor Phase Epitaxy IV. MOVPE and ALE Reaction Mechanisms (MOVPE 단결정층 성장법 IV. MOVPE 및 ALE 반응경로)

  • 정원국
    • Journal of Surface Science and Engineering
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    • v.24 no.1
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    • pp.1.1-1.1
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    • 1991
  • Understanding of the detailed reaction mechanisms during MOVPE and ALE is essential to further improve the properties of the grown crystals and the controllability of the growth parameters. The unified models for the detailed reaction paths are not available at this stage. The study, however, has been advanced to the extent that consensus on some of the reaction paths can be drawn from the scattered data. Metalakyls such as TMGa and TMIn seem to nearly fully decompose in the gas phase through homogeneous reaction at the typical MOVPE growth temperature. Hydrides such as AsH3 and PH3, on the contrary. seem to decompose heterogeneously onthe substrate surfaces as well as homogeneously in the gas phase. However, at lower temperatures, where ALE crystals are typically grown, the growth process is strongly dependent on the surface reactions. It seems that steric hindrance effects which the radicals reaching the substrate exhibit on the surface the growth rate a function of the metalalkyle supply durations. In addition, dydrogens released from hydrides seem to play an essential role in removing carbons leberated from the metalalkyls. High growth temperatures also seem to be effective in desorbing carbons from surface. The understanding of the reaction mechanisms was possible though diverse appraaches utilizing many ex-situ and in-situ diagnostic techniques and genuine experimental designs. It is the purpose of this paper to review and discuss many of these efforts and to draw some possible conclusions from them.

Effects of Impact Velocity on Crystallization and Activation Energy of Cu-based Bulk Metallic Glasses in Kinetic Spray Coating (저온 분사 코팅 공정에서 충돌속도에 따른 CuNiTiZr 벌크 비정질 소재의 활성화 에너지와 결정화 거동 분석)

  • Yoon, Sang-Hoon;Bae, Gyu-Yeol;Kim, Jung-Hwan;Lee, Chang-Hee
    • Journal of Surface Science and Engineering
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    • v.41 no.6
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    • pp.301-307
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    • 2008
  • In this paper, nanocrystallization of CuNiTiZr bulk metallic glass (BMG) subjecting to a kinetic spraying, dependent on impact velocity, was investigated by numerical and experimental approaches. The crystallization fraction and nucleation activation energy of initial feedstock and as-deposited coating were estimated by DSC and Kissinger method, respectively. The results of numerical modeling and experiment showed that the crystalline fraction and nucleation activation energy in BMG coatings were depended on kinetic energy of incident particle. Upon impact, the conversion of particle kinetic energy leads to not only decreasing free energy barrier but also increasing the driving force for an amorphous to crystalline phase transformation. The nanocrystallization of BMGs is associated with the strain energy delivered by a plastic deformation with a high strain rate.

Electrohydrodynamic Jet Process for Pore-Structure-Controlled 3D Fibrous Architecture As a Tissue Regenerative Material: Fabrication and Cellular Activities

  • Kim, Minseong;Lee, Hyeongjin;Kim, GeunHyung
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.134.1-134.1
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    • 2017
  • In this study, we propose a new scaffold fabrication method, "direct electro-hydrodynamic jet process," using the initial jet of an electrospinning process and ethanol media as a target. The fabricated threedimensional (3D) fibrous structure was configured with multilayered microsized struts consisting of randomly entangled micro/nanofibrous architecture, similar to that of native extracellular matrixes. The fabrication of the structure was highly dependent on various processing parameters, such as the surface tension of the target media, and the flow rate and weight fraction of the polymer solution. As a tissue regenerative material, the 3D fibrous scaffold was cultured with preosteoblasts to observe the initial cellular activities in comparison with a solid-freeform fabricated 3D scaffold sharing a similar structural geometry. The cell-culture results showed that the newly developed scaffold provided outstanding microcellular environmental conditions to the seeded cells (about 3.5-fold better initial cell attachment and 2.1-fold better cell proliferation).

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Central Pressor Mechanisms of Bradykinin in 2-Kidney, 1 Clip Goldblatt Hypertensive Rats

  • Yeum, Cheol-Ho;Jun, Jae-Yeoul;Yoon, Pyung-Jin
    • The Korean Journal of Physiology
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    • v.26 no.1
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    • pp.69-74
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    • 1992
  • Central cardiovascular effects of bradykinin were examined in anesthetized normotensive (NTR) and 2-kidney, 1 clip Goldblatt hypertensive rats (GHR). Bradykinin ($0.5{\sim}10nmol$) was administered into the right lateral cerebral ventricle, while blood pressure and heart rate (HR) were continuously monitored. In both NTR and GHR, intracerebroventricular bradykinin produced a dose dependent increase in mean arterial pressure (MAP) without significant changes in HR. GHR were more sensitive in the pressor response than NTR. The pressor response to bradykinin was attenuated by treatment with hexamethonium (2.5mg/kg/min, IV) or phentolamine (2mg/kg, IV) in both NTR and GHR. Reserpine treatment (2mg/kg/day, intramuscularly,2 days) did not affect the central pressor effect of bradykinin in NTR but it attenuated the pressor effect in GHR. Pretreatment with indomethacin (10mg/kg, intraperitoneally) or saralasin ($20{\mu}g$/kg/min, IV) was without effects on the pressor response to bradykinin. These results indicate that the central pressor effect of bradykinin is, at least in part, due to excitation of the autonomic nervous activity. Mechanisms other than the enhanced sympathetic nervous activity ran. not be ruled out, However. It is also suggested that the sensitivity to bradykinin is increased in the GHR.

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A Ternary Polymeric Matrix System for Controlled Drug Delivery of Highly Soluble Drug with High Drug Loading : Diltiazem Hydrochloride (염산 딜티아젬의 방출을 제어하기 위한 삼중 폴리머 매트릭스 시스템)

  • Kim, Hyun-Jo;Fassihi, Reza
    • Journal of Pharmaceutical Investigation
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    • v.31 no.1
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    • pp.19-25
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    • 2001
  • The purpose of this study was to use a ternary polymeric matrix system for high drug loading of a highly soluble drug for controlled release delivery. The controlled drug delivery of diltiazem HCl (solubility > 50% in water at $25^{\circ}C$) with high loading dose (the final loading dose of drug was 34%) from a ternary polymeric matrix (gelatin, pectin, HPMC) was successfully accomplished. This simple monolithic system with 240 mg drug loading provided near zero-order release over a 24 hour-period by which time the system was completely dissolved. The release kinetics of diltiazem HCl tablet with high loading dose from the designed ternary polymeric system was dependent on the ratios of HPMC : pectin binary mixture. The release rate increased as pectin : HPMC ratio were increased. Swelling behavior of the ternary system and the ionic interaction of formulation components with cationic diltiazem molecule appear to control drug diffusion and the release kinetics. Comparable release profiles between commercial product and the designed system were obtained. The binding study between gelatin with diltiazem HCl showed the presence of two binding sites for drug interaction with subsequent controlled diffusion upon swelling. This designed delivery system is easy to manufacture and drug release behavior is highly reproducible and offers advantages over the existing commercial product.

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A Study on the Poverty of Mountain People Depending on Forests

  • NGUYEN, Phuong Thi Minh;NGUYEN, Song Van;DO, Duc Tai;NGUYEN, Quynh Thi Thuy;DINH, Thanh Trung;NGUYEN, Hang Phan Thu
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.7
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    • pp.519-529
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    • 2020
  • Livelihood capitals have a clear influence on livelihood development. As for the livelihood results, it has been pointed out in the analysis of the poor households that the ability of people to escape poverty depends especially on the access to livelihood capitals. This study aims to analyze the impacts of livelihood capital on poverty among mountain people who depend on forests through human capital, social capital, natural capital, physical capital and financial capital. This research employs the model of binary regression function. Independent variables x1, x2, …, xn are targets of livelihood strategy, vulnerability context, and livelihood capitals. These variables were selected to be included in the original model with dependent variable Y as poor and non-poor households. This study surveys households living in upland areas, near forests, and households of ethnic minorities. The results show that,out of the poor household rate, nearly 4% are newly-poor households or those falling back into poverty. Therefore, the government needs to pay more attention to this disadvantaged group and implements policies such as education and training policies, credit support policies, policies to support forest development, and payment for forest environmental services in the context of emerging countries like Vietnam.

Simulation-based Yield-per-recruit Analysis of Pacific cod Gadus macrocephalus in Southeastern Korean Coastal Waters (모의실험을 통한 동남해안 대구(Gadus macrocephalus)의 가입당 생산 분석)

  • Cha, Hyung Kee;Jung, Sukgeun
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.45 no.5
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    • pp.493-498
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    • 2012
  • We derived biological reference points for Pacific cod Gadus macrocephalus in southeastern Korean waters by applying a yield-per-recruit analysis based on a daily simulation that adopted size-dependent fecundity, growth, and natural mortality functions. This showed that the yield per recruit of Pacific cod can be maximized at an instantaneous rate of fishing mortality (F)=0.37 $yr^{-1}$ under the current regulations, where the minimum catch size ($L_c$)=30 cm in total length (TL). The maximum economic yield was estimated to be attained at $L_c$=35-45 cm TL, if F>1 $yr^{-1}$ but at $L_c$=35-40 cm TL, if F<1 $yr^{-1}$. Despite great uncertainty in the stock assessment, to develop fisheries management plans for the sustainable exploitation of Pacific cod in southeastern Korean waters, it is necessary to estimate F using capture-recapture or other expedient methods.

Effects of DME Additives on Combustion Characteristics and Nano-particle Distributions in a Single Cylinder Compression Ignition Engine (DME 연료에 첨가제를 혼합하였을 때의 연소 특성 및 배출가스 특성에 관한 연구)

  • Kwon, Seok-Joo;Cha, June-Pyo;Kang, Min-Gu;Lee, Chang-Sik;Park, Sung-Wook;Lim, Young-Kwan
    • Transactions of the Korean Society of Automotive Engineers
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    • v.20 no.5
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    • pp.19-25
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    • 2012
  • This study describes effects of DME additives on combustion and exhaust emissions characteristics including nano-particle in a single cylinder compression ignition engine. Considered additives include bio-diesel, n-butanol, and MTBE for increasing kinematic viscosity. Among three additives, n-butanol showed the greatest kinematic viscosity. In addition MTBE showed the highest vapor pressure. In the present study mixing ratios of additives were kept constant at 1 and 10% by volume. Experiments were performed at 1200rpm engine speed and nano-particles were measured by SMPS (Scanning mobility particle sizer) devices. Results of combustion characteristics showed that considered additives had little effects on combustion pressure. However, patterns of heat release rate were dependent on properties of additives. Nano-particles of MTBE were the lowest among considered additives.

Microcarrier Culture of an Anchorage-dependent Cell Using Cytodex-3 (Cytodex-3를 이용한 부착성 동물세포의 미립담체 배양)

  • 김정회;최준호;웨이슈후
    • Microbiology and Biotechnology Letters
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    • v.17 no.3
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    • pp.231-235
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    • 1989
  • Possibility of using microcarriers for the growth of a transformed human embryonic kidney cell line 293 was investigated. The cell grew well in a static culture such as T-flasks with medium of DME/F12 (3:1) mixture supplemented with 5% FBS, but it was most difficult to make the cells grow on microcarriers mainly due to the low attachment efficiency and poor spreading at initial stage of the culture. Consequently, 30-50% of the cells were lost upon inoculation into microcarrier suspension and significant fraction of the mirrocarrier became bald. The medium supplemented with the concentrated conditioned medium by hepatoma cell line HpG2 supported the active growth of the cells on microcarrier and the cells showed a very healthy and well spreading morphology. It was probable that some spreading and attachment factors of HpG2 conditioned medium were effective for 293 cells.

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