• Title/Summary/Keyword: rate dependent

Search Result 3,171, Processing Time 0.028 seconds

A Study on the Causes and Consulting Methods to Reduce the Differentiation of Incubator Center (창업보육센터의 보육요소 격차 해소를 위한 변인도출 및 컨설팅 고찰)

  • Yim, Heon-Wook
    • Journal of Convergence for Information Technology
    • /
    • v.8 no.1
    • /
    • pp.313-320
    • /
    • 2018
  • The purpose of the study is to suggest ways to reduce the difference in occupancy rate and cost of incubation centers and surveyed 262 business disclosures of KBIA. the region, the subject of management, and the technology field are set as independent variables among the management disclosure items, and the occupancy rate, cost, and assigned grade are defined as dependent variables. As a result of the correlation analysis, it was found that about 19.4%($R^2=0.194$) and about 7.0%($R^2=0.059$) explain the cost of the operation, Respectively. finally Costs are high in metropolitan areas, public organizations and technology-intensive centers are inexpensive, occupancy rates are high in government and universities, and low in large cities. In order to resolve the gap, $5,720won/m^2$ is appropriate, and the center operates as a technology-intensive specialization center.

A Comprehensive Swelling Model of Silicide Dispersion Fuel for Research Reactor (연구로용 우라늄실리사이드 분산형 핵연료의 팽윤모델)

  • Woan Hwang;Suk, Ho-Chun;Jae, Won-Mok
    • Nuclear Engineering and Technology
    • /
    • v.24 no.1
    • /
    • pp.40-51
    • /
    • 1992
  • One of the important irradiation performance characteristics of the silicide dispersion fuel element in research reactors is the diameteral increase resulting from fuel swelling. This paper, will attempt to develop a physical model for the fuel swelling, DFSWELL, by analyzing the basic irradiation behaviours and some experimental evidences. From the experimental evidences, it was shown that the volume changes in irradiated U$_3$Si-Al were strongly dependent on temperature and fission rate. The quantitative-amount of swelling for silicide fuel is estimated by considering temperature, fission rate, solid fission product build-up and gas bubble behavior. The swelling for the silicide fuel is comprised of three major components : i ) a volume change due to the formation of an interfacial layer between the fuel particle and matrix. ii ) a volume change due to the accumulation of gas bubble nucleation iii ) a volume change due to the accumulation of solid fission products The DFSWELL model which takes into account the above three major physical components predicts well the absolute magnitude of silicide fuel swelling in accordance with the power histories in comparison with the experimental data.

  • PDF

Anti-cancer and -Metastatic Effects of Lactobacillus Rhamnosus GG Extract on Human Malignant Melanoma Cells, A375P and A375SM

  • Lee, Jaehoon;Park, Sangkyu;Seo, Jeongmin;Roh, Sangho
    • International Journal of Oral Biology
    • /
    • v.42 no.3
    • /
    • pp.107-115
    • /
    • 2017
  • Human malignant melanoma is an aggressive skin cancer which has been rising at a greater rate than any other cancers. Although various new therapeutic methods have been developed in previous studies, this disease has properties of high proliferation and metastasis rate which remain obstacles that have lead to a poor prognosis in patients. It has been reported that a specific Lactobacillus extract has anti-cancer and -metastasis effect in vitro and in vivo. However, previous research has not specified precisely what effect the Lactobacillus rhamnosus GG (LGG) extract has had on human malignant melanomas. In this study, we showed that the LGG extract has anti-cancer and -metastasis effects on the human malignant melanoma cell lines, A375P and A375SM. At first, it was found that, while the LGG extract affects human neonatal dermal fibroblasts slightly, it induced the dose-dependent anti-cancer effect on A375P and A375SM by a WST-1 proliferation assay. As a result of a real-time PCR analysis, the expression patterns of several genes related to cell cycle, proliferation, and apoptosis were modulating in a manner that inhibited the growth of both malignant melanoma cell lines after the treatment of the LGG extract. Furthermore, genes related to the epithelial-mesenchymal transition were down-regulated, and migration rates were also decreased significantly by the LGG extract. Our study showed that the LGG extract could be used as a potential therapeutic source.

Growth Inhibition and Apoptosis Induction of Human Umbilical Vein Endothelial Cells by Apogossypolone

  • Zhan, Yong-Hua;Huang, Xiao-Feng;Hu, Xing-Bin;An, Qun-Xing;Liu, Zhi-Xin;Zhang, Xian-Qing
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.3
    • /
    • pp.1791-1795
    • /
    • 2013
  • Aims and Background: Prostate cancer is one of the most common malignant tumors in the male reproductive system, which causes the second most cancer deaths of males, and control of angiogenesis in prostate lesions is of obvious importance. This study assessed the effect of apogossypolone (ApoG2) on proliferation and apoptosis of human umbilical vein endothelial cells (HUVECs). Subjects and Methods: HUVECs were treated with different concentrations of ApoG2. The survival rate of HUVECs were determined by MTT assay. Utrastructural changes of HUVECs were assessed with transmission electron microscopy. Apoptosis in HUVECs was analyzed by flow cytometry and cell migration by Boyden chamber assay. Matrigel assays were used to quantify the development of tube-like networks. Results: ApoG2 significantly inhibited HUVEC growth even at 24 h (P<0.05). The inhibitory effect of ApoG2 is more obvious as the concentration and the culture time increased (P<0.05). These results indicate that ApoG2 inhibits the proliferation of HUVECs in a time- and concentration-dependent manner with increase of the apoptosis rate. Besides, ApoG2 reduced the formation of total pseudotubule length and network branches of HUVECs. Conclusions: The results suggest that ApoG2 inhibits angiogenesis of HUVECs by growth inhibition and apoptosis induction.

Speaker verification system combining attention-long short term memory based speaker embedding and I-vector in far-field and noisy environments (Attention-long short term memory 기반의 화자 임베딩과 I-vector를 결합한 원거리 및 잡음 환경에서의 화자 검증 알고리즘)

  • Bae, Ara;Kim, Wooil
    • The Journal of the Acoustical Society of Korea
    • /
    • v.39 no.2
    • /
    • pp.137-142
    • /
    • 2020
  • Many studies based on I-vector have been conducted in a variety of environments, from text-dependent short-utterance to text-independent long-utterance. In this paper, we propose a speaker verification system employing a combination of I-vector with Probabilistic Linear Discriminant Analysis (PLDA) and speaker embedding of Long Short Term Memory (LSTM) with attention mechanism in far-field and noisy environments. The LSTM model's Equal Error Rate (EER) is 15.52 % and the Attention-LSTM model is 8.46 %, improving by 7.06 %. We show that the proposed method solves the problem of the existing extraction process which defines embedding as a heuristic. The EER of the I-vector/PLDA without combining is 6.18 % that shows the best performance. And combined with attention-LSTM based embedding is 2.57 % that is 3.61 % less than the baseline system, and which improves performance by 58.41 %.

Initiation and Termination of Pupal Diapause in the Oriental Tobacco budworm (Heliothis assulta) (담배나방 (Heliothis assulta) 용휴면의 유기와 종료)

  • 부경생;신현철;한만위;이문홍
    • Korean journal of applied entomology
    • /
    • v.29 no.4
    • /
    • pp.277-285
    • /
    • 1990
  • Laboratory and field studies were conducted to investigate the initiation and termination factors for pupal diapause in the Oriental tabacco budworm, Heliothis assulta Guenee. Diapause induction was dependent of photoperiod and temperature experienced by 4th and 5th instar larve. One hundred percent of pupal diapause was obtained when larvae were grown at 10L/14D or shorter and $20^{\circ}C$. But at $25^{\circ}C$ the maximum rate of diapause was only about 85% at 8L/16D, the shortest photoperiod tested in this experiment. Adults, eggs or pupae did not respond to diapause-inducing environmental conditions. The critical photoperiod was 12-12.5 hr at $25^{\circ}C$and 14-14.5 hr at $20^{\circ}C$. In the field-collected sample 100% of diapuse rate was observed on Sept. 20 and thereafter in Suwon and middle part of Korea. Cold temperature treatment was not necessary in the termination of pupal diapause, but accelerated adult development.

  • PDF

Photocatalytic Cr(VI) Reduction with a Photoanode for Hydrogen Production (수소제조용 광전극을 활용한 Cr(VI) 환원처리에 관한 연구)

  • Shim, Eun-Jung;Park, Youn-Bong;Bae, Sang-Hyun;Yoon, Jae-Kyung;Joo, Hyun-Ku
    • Journal of Hydrogen and New Energy
    • /
    • v.18 no.4
    • /
    • pp.452-457
    • /
    • 2007
  • Titanium foil and mesh(anodized tubular $TiO_2$ electrode, ATTE) were anodized in a bath at $5^{\circ}C$ with 20V external bias applied, then annealed at different temperatures($450^{\circ}C{\sim}850^{\circ}C$) to obtain tubular $TiO_2$ on the Ti substrate. The prepared sample was used to investigate rate of hydrogen production as well as Cr(VI) reduction. The ATTEs annealed at relatively lower temperatures showed higher activity than those at relatively higher temperatures. In particular, the Cr(VI) reduction was pH-dependent. To improve photocatalytic Cr(VI) reduction with the ATTEs, two configurations, fixing foil type and rotating mesh type, were also compared. As a result, the rotating mesh type was much more effective for Cr(VI) reaction than the former due to the more efficient use of the light. In the rotating type reactor, as the rotating speed increased, the rate of the Cr(VI) reduction was getting faster.

Culturing Method and Dietary Value of Benthic Copepod, Tigriopus japonicus (부착성 요각류, Tigriopus japonicus의 배양방법 및 먹이효율)

  • 박흠기;허성범;김철원
    • Journal of Aquaculture
    • /
    • v.11 no.2
    • /
    • pp.261-269
    • /
    • 1998
  • The harpacticoid copepod, Tigriopus japonicus is one of the important zooplankton as a live food the production of marine fish fry. This reserch was carried out to investigate the culturing method and dietary value of T. japonicus. The reproduction of this copepod was analysed in the culturing systems (tne opened and the closed systems) and the surface area of the substate plates for the mass culture. Survival rate of the mature female and the number of nauplii produced per female for two day was higher in the open culturing system than in the close system. However, the result of survival rate of the nauplius was reversed. Larger surface area of the culturing vessel accommodated higher density of this bentic copepod. In polyculture of T. japonicus and rotifer (B. plicatilis), growth of T. japonicus seems to be dependent on the rotifer density. But rotifer seems to be independent on the copepod. With regard to dietary value, this copepod is better than Artemia nauplius for the larvae of red sea bream and tiger puffer which feed by picking. However, it is inadequate for bottom fish larvae as flounder.

  • PDF

Optimized Design and Manufacture of Wideband Pulsed Gamma-ray Sensors (광대역 펄스감마선 탐지센서 최적화 설계 및 제작)

  • Jeong, Sang-hun;Lee, Nam-ho
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.21 no.1
    • /
    • pp.223-228
    • /
    • 2017
  • In this paper, we are proposing an optimal design of wideband pulsed type gamma-ray sensors. These sensors were manufactured based on the design results and after word electrical properties were analyzed. The sensor input parameters were derived on the basis of pulsed gamma-ray spectrum and time-dependent energy rate, and the output current which were derived on the basis of the sensor sensitivity control circuit. Pulsed gamma-ray sensors were designed using the TCAD simulators. The design results show that the optimal Epi layer thickness is 45um with the applied voltage 3.3V and the diameter is 2.0mm. The doping concentrations are as follows : N-type is an Arsenic as $1{\times}10^{19}/cm^3$, P-type is a Boron as $1{\times}10^{19}/cm^3$ and Epi layer is Phosphorus as $3.4{\times}10^{12}/cm^3$. The fabricated sensor was a leakage current, 12pA at voltage -3.3V and fully depleted mode at voltage -5V. A test result of pulsed radiation shows that the sensor gives out the optimal photocurrent.

Numerical Study on the Thermal Environment of a Natural Light Based Multi-layered Plant Factory (자연광 기반 적층형 식물공장의 열환경에 대한 수치해석 연구)

  • Park, Dong Yoon;Jang, Seong-Teak;Chang, Seong-Ju
    • KIEAE Journal
    • /
    • v.13 no.5
    • /
    • pp.43-50
    • /
    • 2013
  • Recent researches on plant factory system deal with the convergence of lighting technology, agricultural technology inclusive to the high-tech industries worldwide in order to respond to the decreasing crop harvest due to global warming and abnormal weather phenomena. However, the fundamental performance standard is not currently being introduced in the case of plants factory and its commercialization is not activated because of high initial investment and operating cost. Large portion of the initial investment and operating cost of a plant factory is ascribed to artificial light sources and thermal control facilities, therefore, innovation should be provided in order to improve the economics of the plant factory. As an alternative, new plant factory could harness solar thermal and geothermal systems for heating, cooling and ventilation. In this study, a natural light dependent multi-layer plant factory's thermal environment was analyzed with two-dimensional numerical methods to elicit efficient operation conditions for optimized internal physical environment. Depending on the supply air temperature and airflow rate introduced in the facility, the temperature changes around the crops was interpreted. Since the air supplied into the plant factory does not stay long enough, the ambient temperature predicted around the plating trays was not significantly different from that of the supplied air. However, the changes of airflow rate and air flow pattern could cause difference to the temperature around the planting trays. Increasing the amount of time of air staying around the planting trays could improve energy performance in case the thermal environment of a natural light based multi-layer plant factory is considered.