• The Journal of Korean Institute of Communications and Information Sciences
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• v.27 no.1B
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• pp.90-98
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• 2002

To increase system capacity in WCDMA receiver, the coherent detection is an essential technology for recovering transmitted symbols correctly. For coherent detection, an accurate and fast channel estimation is required. In next generation mobile communication system, high frequency carriers are used, and high data rate services are provided for subscribers having high mobility. In this communication environment, however, the rapidly-changing doppler frequency degrades the quality of the transmitted signal a lot. In WCDMA system, the channel estimation is conducted using pilot channel and/or pilot symbols which are known to both transmitter and receiver. Some existing channel estimation algorithms utilize these information quite well, but the performance of channel estimation gets very poor in a complicated fading channel distorted by the doppler effect. In this paper, we propose a new channel estimation algorithm combining an early-late doppler compensator so that the doppler effect and the fading characteristics are compensated at the same time. By computer simulation, the proposed algorithm proved to be a much more efficient channel estimation method in the fast fading channel, even at reasonably low Eb/No.

• Journal of Korean Society of Water and Wastewater
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• v.14 no.1
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• pp.54-61
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• 2000

Recently, our circumstances are threatened by an accident that leakage of under ground storage tank and illegal dumping of synthetic organic compounds at chemical plants and many treatment methods, Activated carbon adsorption, Ozonization, Membrane filtration and Photocatalystic oxidation, are developed to remove such a synthetic organic compounds. And it has reported that Activated carbon adsorption have a great removal efficiency to nondegradable matters and organic compounds which have a high molecular weight. Comparing with other adsorbents, Activated carbon adsorption have a worse efficiency when ad desorption speed is low. Thus improved type of adsorbents was invented and one of those is Activated Carbon Filter. The purpose of this study was getting information about adsorption characteristic phenol which can be applied Activated Carbon Fiber and Granular Activated Carbon. In detail, With comparing removal characteristics of phenol in the presence Humic Acid using Activated Carbon Fiber(ACF) and Granular Activated. Carbon(GAC), it is to certify an effective application of Activated Carbon Fiber. At the range of this study, Batch test, Isotherm adsorption test and Factorial analysis, following conclusion were obtained from the results of this study. Batch test was carried to know time of adsorption equilibrium. In this study about time of adsorption equilibrium by ACF was faster than GAC's, for developed micropore of ACF. From the result of phenol adsorption test, High removal rate of adsorption is shown at pH 5. The result of lsotherm adsorption test, it has represented that the Freundlich's isotherm is most suitable one in others, that a ACF's adsorption capacity is more excellent than GAC's. Adsorption of phenol exiting humic acid is decreased getting raised humic acid concentration. Since ACF's micropore is developed at this time, an effect of high molecular humic acid is lower. Factorial analysis was carried to know about Main effect which was injection dosage of adsorbent in the range of this study.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.1845-1849
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• 2012

Objective: Tissue factor (TF) is expressed abnormally in certain types of tumor cells, closely related to invasion and metastasis. The aim of this study was to construct a human gastric cancer cell line SGC7901 stably-transfected with human TF, and observe effects on oxaliplatin-dependent inhibition of invasion and the apoptosis induction. Methods: The target gene TF was obtained from human placenta by nested PCR and introduced into the human gastric cell line SGC7901 through transfection mediated by lipofectamine. Stably-transfected cells were screened using G418. Examples successfully transfected with TF-pcDNA3 recombinant (experimental group), and empty vector pcDNA3 (control group) were incubated with oxaliplatin. Transwell chambers were used to show change in invasive ability. Caspase-3 activity was detected using a colorimetric method and annexin-V/PI double-staining was applied to detect apoptosis. Results: We generated the human gastric cancer cell line SGC7901/TF successfully, expressing TF stably and efficiently. Compared with the control group, invasion increased, whereas caspase-3 activity and apoptosis rate were decreased in the experimental group. Conclusion: TF can enhance the invasive capacity of gastric cancer cells in vitro. Its increased expression may reduce invasion inhibition and apoptosis-inducing effects of oxaliplatin and therefore may warrant targeting for improved chemotherapy.

• Journal of Microbiology and Biotechnology
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• v.9 no.3
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• pp.235-242
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• 1999

We investigated the growth-inhibitory mechanism of Helicobacter pylori by omeprazole (OMP) and its activated sulfenamide (OAS). Using dithiothreitol (DTT) and 5,5'-dithio-bis[2-nitrobenzoic acid] (DTNB; Ellman's reagent), we first determined the relationship between the binding capacity of these compounds to H. pylori membrane and its significance to membrane P-type ATPase activity. After incubation of the intact H. pylori cells with either OMP or OAS, the residual quantity of free SH-groups on the cell membrane was measured, and, the resulting values were plotted as a function of time. From this experiment, we found that there was a considerable difference in the membrane-binding rates between OMP and OAS. At neutral pH, the disulfide bond formation on H. pylori membrane was completed within 2 min of incubation of the intact cells with OAS. By OMP, however, it was gradually formed, exceeding 10 min of incubation for completion, whereby, the extent of P-type ATPase inhibition appeared to be proportional to the disulfide forming rate. From this data, it was suggested that the disulfide formation might directly affect enzyme activity. Since OMP per se cannot yield a disulfide bond with cysteine, it is predicted that the enzyme inactivation must be caused by the OAS form. Accordingly, we postulated that, under the neutral pH, OMP could be converted to OAS in the course of transport. By extrapolating the inhibitory slopes, we could evaluate K₁ values, relating to their minimal inhibitory concentrations (MICs) for H. pylori growth. In these MIC ranges, H. pylori uptake or vesicular export of nutrients such as peptides were totally prohibited, but their effect in Escherichia coli were negligible. From these observations, we strongly suggest that the P-type ATPase activity is essential for the survival of H. pylori cells in particular.

• Korean Journal of Pharmacognosy
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• v.46 no.1
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• pp.38-43
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• 2015

Ligularia stenocephala has a wide range of types of constituents with various pharmacological properties. Here in this study, we examined the effect of methanolic extract of L. stenocephala (MLS) on the lifespan and stress tolerance using Caenorhabditis elegans model system. We found that lifespan of wild-type worms was significantly lengthened in the presence of MLS in a dose dependent manner. MLS also elevated the tolerance of worms against osmotic, heat shock, and oxidative stress. We also demonstrated in vivo antioxidant capacity of MLS by checking intracellular reactive oxygen species levels as well as antioxidant enzyme activities such as catalase and superoxide dismutase. We further investigated several aging-related factors, including pharyngeal pumping rate and body length. Here, we showed that MLS exerts longevity effect independent of both factors. In addition, body movement of aged worms was significantly elevated, suggesting MLS could enhance healthspan as well as lifespan.

• Magazine of the Korean Society of Agricultural Engineers
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• v.30 no.4
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• pp.94-108
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• 1988

The use of geotextile as reinforcing materials in soil structures has become widespread throughout the world. Geotextile reinforcement has been used in retaining walls, roadbed, embankment stabilization and especially reinforcement of soft foundation, and so on, In the past, however, its design and construction have been performed empirically. In this study, laboratory model tests were carried out in order to investigate the effects of geotextile rein- forcement on vertical and horizontal displacement and other characteristics in soft founda- tions. The experiments were executed in eight treatments ;no geotextile between embank - ment and subsoils, and seven geotextiles with different tensile strength. And such factors as the loading conditions, the tensile strength of geotextiles, the ingredient of geotextiles and the elapsed time were investigate in this study. And the analytical method were executed in order to study the stress and behavior of geotextile - reinforced soil structure by the nonlinear elasto - plastic finite element model. The following conclusions were drawn from this study. 1. Geotextile reinforcement reduced the effects of banking loads on subsoils more effectively with the increase of their tensile strength. 2. As the tensile strength of geotextiles was increase, the rate of the initial vertical disp - lacements of loading plate was reduced inverse proportional to loads, Rowever, the effect of loading was reduced when the loads exceed a certain limits, 3. The effect of reinforcement of nonwoven geotextile was 1.5-4.5 times larger than that of the woven geotextile with equivalent tensile strength. 4. The increased bearing capacity and the reduced settlement are proportioned as the tensile strength of geotextile. 5. The settlement at the long time loading were developed almost all, were completed after 10 days and the additional settlement were not developed since then. 6. The nonlinear elasto - plastic finite element method are accurate to predict the stresses and behayior of geotextile - reinforced soil structures.

• Food Science of Animal Resources
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• v.34 no.3
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• pp.362-371
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• 2014

This study utilized commercially available proteolytic enzymes to prepare egg-white protein hydrolysates (EPHs) with different degrees of hydrolysis. The antioxidant effect and functionalities of the resultant products were then investigated. Treatment with Neutrase yielded the most ${\alpha}$-amino groups (6.52 mg/mL). Alcalase, Flavourzyme, Protamex, and Ficin showed similar degrees of ${\alpha}$-amino group liberation (3.19-3.62 mg/mL). Neutrase treatment also resulted in the highest degree of hydrolysis (23.4%). Alcalase and Ficin treatment resulted in similar degrees of hydrolysis. All hydrolysates, except for the Flavourzyme hydrolysate, had greater radical scavenging activity than the control. The Neutrase hydrolysate showed the highest 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity ($IC_{50}=3.6mg/mL$). Therefore, Neutrase was identified as the optimal enzyme for hydrolyzing egg-white protein to yield antioxidant peptides. During Neutrase hydrolysis, the reaction rate was rapid over the first 4 h, and then subsequently declined. The $IC_{50}$ value was lowest after the first hour (2.99 mg/mL). The emulsifying activity index (EAI) of EPH treated with Neutrase decreased, as the pH decreased. The EPH foaming capacity was maximal at pH 3.6, and decreased at an alkaline pH. Digestion resulted in significantly higher 1,1-diphenyl-2-picrylhydrazyl (DPPH) and ABTS radical scavenging activity. The active peptides released from egg-white protein showed antioxidative activities on ABTS and DHHP radical. Thus, this approach may be useful for the preparation of potent antioxidant products.

• Journal of Hydrogen and New Energy
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• v.22 no.6
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• pp.780-786
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• 2011

Mg hydride had high hydrogen capacity (7.6%), lightweight and low cost materials and it was promising hydrogen storage material at high temperature. However, commercial applications of the Mg hydride are currently hindered by its high absorption/desorption temperature, and very slow reaction kinetics. one of the approaches to improve the kinetic is $MgH_x$ intermixed with carbon. And it shows that carbon and carbon allotropes have a beneficial effect on hydrogen sorption in Mg. The graphene is a kind of carbon allotropes which is easily desorbed reaction at low temperatures because its reaction is exothermic. In this work, the effect of graphene concentration on the kinetics of Mg hydrogen absorption reaction was investigated. The $MgH_x$-Graphene composites has been prepared by hydrogen induced mechanical alloy (HIMA). The synthesized powder was characterized by XRD and simultaneous TG, DSC analysis. The hydrogenation behaviors were evaluated by using a sievert's type automatic PCT apparatus. In this research, results of kinetic profiles exhibit hydrogen absorption rate of $MgH_x$-5wt.% and 10wt.% graphene composite, as 1.25wt.%/ms, 10.33wt.%/ms against 0.88wt.%/ms for $MgH_x$ alone at 473K.

• Molecules and Cells
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• v.40 no.8
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• pp.558-566
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• 2017

Regular monitoring on experimental animal management found the fluctuation of ART outcome, which showed a necessity to explore whether superovulation treatment is responsible for such unexpected outcome. This study was subsequently conducted to examine whether superovulation treatment can preserve ultrastructural integrity and developmental competence of oocytes following oocyte activation and embryo culture. A randomized study using mouse model was designed and in vitro development (experiment 1), ultrastructural morphology (experiment 2) and functional integrity of the oocytes (experiment 3) retrieved after PMSG/hCG injection (superovulation group) or not (natural ovulation; control group) were evaluated. In experiment 1, more oocytes were retrieved following superovulation than following natural ovulation, but natural ovulation yielded higher (p < 0.0563) maturation rate than superovulation. The capacity of mature oocytes to form pronucleus and to develop into blastocysts in vitro was similar. In experiment 2, a notable (p < 0.0186) increase in mitochondrial deformity, characterized by the formation of vacuolated mitochondria, was detected in the superovulation group. Multivesicular body formation was also increased, whereas early endosome formation was significantly decreased. No obvious changes in other microorganelles, however, were detected, which included the formation and distribution of mitochondria, cortical granules, microvilli, and smooth and rough endoplasmic reticulum. In experiment 3, significant decreases in mitochondrial activity, ATP production and dextran uptake were detected in the superovulation group. In conclusion, superovulation treatment may change both maturational status and functional and ultrastuctural integrity of oocytes. Superovulation effect on preimplantation development can be discussed.

• Journal of the Korean Institute of Educational Facilities
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• v.16 no.6
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• pp.3-12
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• 2009

Reports on population movement(2000-2030) by the National Statistical Office show that the number of elementary school age population will be decreased by 1.4million from 2005 to 2020. It will effect both school size and the policies for school facilities, which have focused on downsizing class as the high standard of OECD nations. As the unfolding evidence is emerging that a number of schools and classes will be emptied out by 2030. This study aims at developing a objective and scientific device for estimate the number of students at future and evaluating the validity of school establishment. In doing so, it explores the relationship between the changing factors and the number of students. It proposes four factors such as the changes of population, the fertility rate, the number of apartment occupant and movement of population. As the result of the statistic analysis on the correlation coefficient, it finds out that the change of apartment occupant has a close correlation with the change in the number of student and has a deep effect on the establishment of school. Finally, it shows the construction of school according to urban developments during 1999-2008 in Incheon Metro-City. This study would help the authorities to expect the future number of student and to restrict overbuilding of surplus classes, finally the reasonable expenditure for school facilities.