• Title/Summary/Keyword: rare events

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Transient Myocardial Thickening in a 4-year-old Korean Domestic Shorthair Cat

  • Yunhee Joung;Hyerin Ahn;Jeongbae Choi;YoungMin Yun;Woo-Jin Song
    • Journal of Veterinary Clinics
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    • v.41 no.2
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    • pp.106-111
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    • 2024
  • A 4-year-old neutered female domestic shorthair cat weighing 5.1 kg was referred to Jeju National University Hospital with acute onset respiratory distress, weakness, and anorexia. The patient had a history of stressful antecedent events that involved bullying by a newly introduced cat. Thoracic radiography and echocardiography revealed a stage C hypertrophic cardiomyopathy phenotype based on the American College of Veterinary Internal Medicine classification system with pulmonary edema, pleural effusion, and pericardial effusion at the same time. The patient was treated with furosemide, pimobendan, and rivaroxaban. Pericardiocentesis was performed because pericardial effusion was identified. Reevaluation after 30 days revealed a normal respiratory rate on physical examination, normal cardiac shape on thoracic radiographs, and normal cardiac measurements on echocardiography. The patient was tentatively diagnosed with transient myocardial thickening (TMT) and all medications were discontinued. Six months after the initial hospitalization, the cat continued to do well without any clinical signs or left ventricular wall thickening. This case is the first report describing feline TMT in Korea. Moreover, it involves a rare case in which pulmonary edema, pleural effusion, and pericardial effusion, which induce cardiac tamponade, occurred simultaneously due to TMT-related congestive heart failure.

Management of complications related to colorectal endoscopic submucosal dissection

  • Tae-Geun Gweon;Dong-Hoon Yang
    • Clinical Endoscopy
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    • v.56 no.4
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    • pp.423-432
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    • 2023
  • Compared to endoscopic mucosal resection (EMR), colonoscopic endoscopic submucosal dissection (C-ESD) has the advantages of higher en bloc resection rates and lower recurrence rates of colorectal neoplasms. Therefore, C-ESD is considered an effective treatment method for laterally spread tumors and early colorectal cancer. However, C-ESD is technically more difficult and requires a longer procedure time than EMR. In addition to therapeutic efficacy and procedural difficulty, safety concerns should always be considered when performing C-ESD in clinical practice. Bleeding and perforation are the main adverse events associated with C-ESD and can occur during C-ESD or after the completion of the procedure. Most bleeding associated with C-ESD can be managed endoscopically, even if it occurs during or after the procedure. More recently, most perforations identified during C-ESD can also be managed endoscopically, unless the mural defect is too large to be sutured with endoscopic devices or the patient is hemodynamically unstable. Delayed perforations are quite rare, but they require surgical treatment more frequently than endoscopically identified intraprocedural perforations or radiologically identified immediate postprocedural perforations. Post-ESD coagulation syndrome is a relatively underestimated adverse event, which can mimic localized peritonitis from perforation. Here, we classify and characterize the complications associated with C-ESD and recommend management options for them.

Establishment of Crowd Management Safety Measures Based on Crowd Density Risk Simulation (군중 밀집 위험도 시뮬레이션 기반의 인파 관리 안전대책 수립)

  • Hyuncheol Kim;Hyungjun Im;Seunghyun Lee;Youngbeom Ju;Soonjo Kwon
    • Journal of the Korean Society of Safety
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    • v.38 no.2
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    • pp.96-103
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    • 2023
  • Generally, human stampedes and crowd collapses occur when people press against each other, causing falls that may result in death or injury. Particularly, crowd accidents have become increasingly common since the 1990s, with an average of 380 deaths annually. For instance, in Korea, a stampede occurred during the Itaewon Halloween festival on October 29, 2022, when several people crowded onto a narrow, downhill road, which was 45 meters long and between 3.2 and 4 meters wide. Precisely, this stampede was primarily due to the excessive number of people relative to the road size. Essentially, stampedes can occur anywhere and at any time, not just at events, but also in other places where large crowds gather. More specifically, the likelihood of accidents increases when the crowd density exceeds a turbulence threshold of 5-6 /m2. Meanwhile, festivals and events, which have become more frequent and are promoted through social media, garner people from near and far to a specific location. Besides, as cities grow, the number of people gathering in one place increases. While stampedes are rare, their impact is significant, and the uncertainty associated with them is high. Currently, there is no scientific system to analyze the risk of stampedes due to crowd concentration. Consequently, to prevent such accidents, it is essential to prepare for crowd disasters that reflect social changes and regional characteristics. Hence, this study proposes using digital topographic maps and crowd-density risk simulations to develop a 3D model of the region. Specifically, the crowd density simulation allows for an analysis of the density of people walking along specific paths, which enables the prediction of danger areas and the risk of crowding. By using the simulation method in this study, it is anticipated that safety measures can be rationally established for specific situations, such as local festivals, and preparations may be made for crowd accidents in downtown areas.

Textural Implications of Fine-Grained Peridotite Xenoliths in Basaltic Rocks from Jeju Island (제주도 현무암에 포획된 세립질 맨틀 페리도타이트 포획암의 조직적 특성)

  • Yang, Kyoung-Hee;Nam, Bok-Hyun;Kim, Jin-Seop;Szabo, Csaba
    • Journal of the Mineralogical Society of Korea
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    • v.22 no.1
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    • pp.1-11
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    • 2009
  • Fine-grained peridotite xenoliths are rarely trapped in the basaltic rocks from the southeastern part of Jeju Island. Based on textural characteristics of the constituent phases showing uniform-sized, fine-grained tabular to mosaic grains with rare porphyroclastic relics, the studied samples can be defined as fine-grained, foliated porphyroclastic peridotites (FPP). Almost no significant difference among the FPPs in textures and major element compositions implies that the FPPs were derived from a structural domain, experiencing similar deformation events and deformation patterns. Moreover, the bimodal distribution with kink-banded porphyroclasts ($2{\sim}3mm$) and stain-free neoblasts ($200{\sim}300{\mu}m$), straight to gently curved grain boundaries with triple junctions, interstitial melt pockets, and microstructures for migrating grain boundary suggest that the studied samples went through dynamic recrystallization (${\pm}$ static recrystallization) in the presence of melt/fluid movement along foliation planes. No notable difference between the FPP and common protogranular xenoliths in major element compositions and geochemical evolution also implies that the FPP and protogranular xenoliths were from a similar horizon. Thus, the textural and geochemical characteristics of the FPPs reflects deformation events occurred at a localized and narrow zone within the lithospheric mantle beneath the Jeju Island. Although further detailed studies are necessary to define deformation events, the most possible process which could trigger deformation in the FPP in the rigid upper mantle was the ascending basaltic magma forming high-stress deformation zones. The suggested high-stress deformation zones in the lithosphere beneath the Jeju Island may be produced by paleo-faulting events related to the ascent of basalt magma before Jeju Island was formed.

Differential Lung Ventilation Therapy for Reexpansion Pulmonary Edema - Report of 2 cases - (분리형 폐환기법을 이용한 재팽창성 폐부종의 치료 -2예 보고 -)

  • 김덕실;김성완;김대현;이응배;전상훈
    • Journal of Chest Surgery
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    • v.36 no.7
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    • pp.527-530
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    • 2003
  • Reexpansion pulmonary edema is a rare complication of the treatment of lung collapse secondary to pneumothorax, pleural effusion, or atelectasis. But occasionally, severe morbidity and death may result. Reexpansion pulmonary edema occurs when chronically collapsed lung is rapidly reexpanded by evacuation of large amounts of air or fluid. In the treatment of the chronically collapsed lung, physicians must remember the possible events and prevent the complications. When the difference in airway resistance or lung compliance between the two lungs is exaggerated, conventional mechanical ventilation might lead to preferential ventilation with hyperexpansion of one lung and gradual collapse of the other. Differential ventilation has been advocated to avert this problem. By differential lung ventilation, we successfully treated a severe reexpansion pulmonary edema in two patients. Therefore we suggest that differential lung ventilation is the treatment of choice for severe reexpansion pulmonary edema.

A Case Report of Extensive Limb Swelling in Newborn After Vaccination: Unusual Thigh Swelling After Hepatitis B vaccination (신생아 B형 간염 예방 접종 후 하지 부종이 발생한 환아 치험 1례)

  • Han, Ju Hui;Kim, Deog Gon;Lee, Jin Yong
    • The Journal of Pediatrics of Korean Medicine
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    • v.28 no.1
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    • pp.52-60
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    • 2014
  • Objectives The purpose of this study is to report the clinical effects of oriental medical treatment on Extensive limb swelling which is rare adverse reaction of vaccination. Methods A 11 months old infant who appealed unilateral thigh swelling after immunization and signs of local inflammation was administered a complex herbal medicine consisting of five decoctions; Gwakhyangjunggisan, Binsosan, Danggwisusan, Samchulgunbitang and Gwibitang. The length of the constant regions of the thigh circumference was measured every visit. Each process was recorded by photograph. After one year from the first visit, phone call was conducted to follow-up. Results The length of the thigh after administration of herbal medicine did not change much, but the part where swelled hard became little bit softer. A year later, patient's growth and walking was normal but the swollen part not changed. Since then the similar adverse effects did not recur on booster doses vaccines. Conclusions The adverse reactions of vaccination are rarely reported and there is no specific treatment for swelling from Hepatitis B vaccine. It will be more helpful to study if more cases reported about any adverse drug reactions or any side effects from the immunization.

Design of Priest Naong's Memorial Area (나옹선사 기념관지구 설계)

  • 홍광표;허상현
    • Journal of the Korean Institute of Landscape Architecture
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    • v.30 no.4
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    • pp.82-91
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    • 2002
  • The site for this plan is located at the foot of Mt. Unseo at Galcheon-ri, Changsu-myon, Youngdeok-gun. On the site stands Jangyutsa Temple, built by priest Naong in 1355 (in the 4th year of King Gongmin during Koryo Kingdom). The purpose of this plan is to widely publicize and commemorate priest Naong by designing a district centering around the temple. The basic directions of design can be summarized as follows 1) A special Buddhists'pilgrimage and sight-seeing district aimed at commemorating priest Naong will be developed to preserve the historic figure of priest Naong. To this end, a facility will be built to collect, preserve and exhibit materials related with the great priest in order to preserve his legacy and enhance the image of the space. 2) Special fractions which are rare in other districts will be introduced to create an image different from the conventional memorial districts or sight-seeing zones. To this end, the district will be divided into the Jangyuksa Temple area proper and a district memorial area, each of which will have its own unique characteristics with different functions. On the other hand, the two different areas will be related with each other and complemented by each other. Such planning techniques as articulation and superimposition will be used for a synergistic effect. 3) The plan will accommodate various programs centering around historical and cultural assets, and at the same time will allow tourists to have various experiences and access to the natural environment as well as to a variety of events. 4) In order to plan such landscapes as shown in the traditional mountain temples, the traditional tectonic forms will be used for the facilities. It is expected that the district surrounding Jangyuksa Temple will become a popular sight-seeing destination, and with new historical and cultural environments will become a valuable resource to widely publicize the culture of Youngdeok-gun.

A study on the Status of Environmental Education and Nautural Environmental Awareness among the Company Employees of Metropolitan Seoul (수도권 거주 직장인들의 환경교육 현황 및 자연환경의식 조사에 관한 연구)

  • Yang, In-Sook;Choi, Kyung-Hee;Lee, Sang-Don
    • Journal of Environmental Impact Assessment
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    • v.15 no.3
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    • pp.217-225
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    • 2006
  • The purpose of this study is to promote the status of environmental education and environmental awareness among employees in company levels. To achieve the study purpose we measured the infrastructure of companies (e.g., re-education programs and social contribution activities) and how these enhance environmental awareness to the employees. The survey was conducted by questioning 100 company employees. The questionnaire was composed of two parts : 1) environmental pollution and 2) nature conservation. The Chi-square test and one-way ANOVA was applied to compare groups. The results can be summarized as follows : First, the environmental education for employees in companies is insufficient; however, environmental education should be necessary and the employees provided with environmental education by their companies appeared to be highly satisfied (p<0.05) than groups without appropriate environmental education. Second, volunteer workers for participating environmental education programs and events are rare; however, employees who participated in volunteer efforts scored the highest in environmental awareness. Third, those that participated in environmental education programs and volunteer works were ranked the highest in environmental awareness (p<0.05) in 10 categories of questions. Based on the study, the environmental education and the volunteer work appeared to be effective tools in boosting environmental awareness among company workers. In conclusion, environment oriented volunteer work is an effective way to improve environmental awareness toward adults.

Molecular Genetic Analysis of Leaf Senescence in Arabidopsis

  • Woo, Hye-Ryun;Lee, Ung;Cho, Sung-Whan;Lim, Pyung-Ok;Nam, Hong-Gil
    • Korean Journal of Plant Tissue Culture
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    • v.27 no.4
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    • pp.259-268
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    • 2000
  • Senescence is a sequence of biochemical and physiological events that lead to death of a cell, organ, or whole organism. Senescence is now clearly regarded as a genetically determined and evolutionarilly acquired developmental process comprising the final stage of development. However, in spite of the biological and practical importance, genetic mechanism of senescence has been very limited. Through forward and reverse genetic approaches, we are trying to reveal the molecular and genetic mechanism of senescence in plants, employing leaf organs of Arabidopsis as a model system. Using forward genetic approach, we have initially isolated several delayed senescence mutants either from T-DNA insertional lines or chemical-mutagenized lines. In the case of ore 4 and ore 9 mutants, the mutated genes were identified. The recent progress on characterization of mutants and identification of the mutated genes will be reported. We are also screening mutations from other various sources of mutant pools, such as activation tagging lines and promoter trap lines. Two dominant senescence-delayed mutants were isolated from the activation tagging pool. Cloning of the genes responsible for this phenotype is in progress. For reverse genetic approach, the genes that induced during leaf senescence were first isolated by differential screening method. We are currently using PCR-based suppression subtractive hybridization, designed to enrich a cDNA library for rare differentially expressed transcripts. Using this method, we have identified over 35 new sequences that are upregulated at leaf senescence stage. We are investigating the function of these novel genes by systemically generating antisense lines.

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The Clinical Features of Spinal Leptomeningeal Dissemination from Malignant Gliomas

  • Bae, Jung-Sik;Yang, Seung-Ho;Yoon, Woan-Soo;Kang, Seok-Gu;Hong, Yong-Kil;Jeun, Sin-Soo
    • Journal of Korean Neurosurgical Society
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    • v.49 no.6
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    • pp.334-338
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    • 2011
  • Objective : The incidence of leptomeningeal dissemination from malignant glioma is rare, so the clinical features of this are not well documented yet We attempted to determine the clinical features of leptomeningeal dissemination from malignant gliomas. Methods : We retrospectively analyzed 11 cases of leptomeningeal dissemination of malignant glioma, who were treated at our institution between 2006 and 2009. We investigated the clinical features of these patients by considering the following factors : tumor locations, the events of ventricular opening during surgery and the cerebrospinal fluid (CSF) profiles, including the cytology. Results : The group was composed of 9 males and 2 females. The histological diagnosis of their initial intracranial tumors were 4 primary glioblastoma, 3 anaplastic astrocytoma, 1 anaplastic oligoastrocytoma, 2 ganglioglioma and 1 pleomorphic xanthoastrocyotma with anaplastic features. The mean age of the patients at the time of the initial presentation was $42.8{\pm}10.3$ years. The mean time between surgery and the diagnosis of spinal dissemination was $12.3{\pm}7.9$ (3-28) months. The mean overall survival after dissemination was $2.7{\pm}1.3$ months. All our patients revealed a history of surgical opening of the ventricles. Elevated protein in the CSF was reported for eight patients who had their CSF profiles checked. Conclusion : We propose that in the malignant gliomas, the surgical opening of ventricles can cause the spinal leptomeningeal dissemination and the elevated protein content of CSF may be a candidate marker of leptomeningeal dissemination.