• Title/Summary/Keyword: rapid measurements

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Consensus Clustering for Time Course Gene Expression Microarray Data

  • Kim, Seo-Young;Bae, Jong-Sung
    • Communications for Statistical Applications and Methods
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    • v.12 no.2
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    • pp.335-348
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    • 2005
  • The rapid development of microarray technologies enabled the monitoring of expression levels of thousands of genes simultaneously. Recently, the time course gene expression data are often measured to study dynamic biological systems and gene regulatory networks. For the data, biologists are attempting to group genes based on the temporal pattern of their expression levels. We apply the consensus clustering algorithm to a time course gene expression data in order to infer statistically meaningful information from the measurements. We evaluate each of consensus clustering and existing clustering methods with various validation measures. In this paper, we consider hierarchical clustering and Diana of existing methods, and consensus clustering with hierarchical clustering, Diana and mixed hierachical and Diana methods and evaluate their performances on a real micro array data set and two simulated data sets.

A study on the formation and mechanical properties of the spray deposits by thermal spray (용사법에 의한 용사층의 형성과 기계적 성질에 관한 연구)

  • 최기영;박동환;김명호
    • Journal of Welding and Joining
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    • v.7 no.3
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    • pp.55-62
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    • 1989
  • Variation of the spray droplet velocity with spraying distance and the microstructural characteristics of spray deposits fromed by oxy-fuel thermal spraying with Ni-base alloy powder contained chrome boride for hard facing were examined. Measurements of spray droplet velocity as a function of distance from the nozzle tip were inexcellent agreement with computer simulated predictions. Optimum condition for thermal spray deposits in this experiment was found to be under #10kg/cm^2$ of acceleration gas pressure with 15cm of spraying distance. Fine microstructure and higher microhardness of the initial part of the deposits due to rapid solidification were found to be able to maintained in a thickness up to 0.4mm, and this initial microstructure and properties could be maintained throughout the thickness of a thick spray deposits by performing the multipass spraying with 0.4mm thickness of each pass.

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EIT Image Reconstruction using Genetic Algorithm

  • Kim, Ho-Chan;Moon, Dong-Chun;Kim, Min-Chan;Lee, Yoon-Joon
    • 제어로봇시스템학회:학술대회논문집
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    • 2001.10a
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    • pp.60.4-60
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    • 2001
  • Electrical impedance tomograpy (EIT) determines the resistivity distribution inside an inhomogeneous target by means of voltage and current measurements conducted at the target boundary. In this paper, a genetic algorithm (GA) approach is proposed for the solution of the EIT image reconstruction. Results of numerical experiments of EIT solved by the GA approach are presented and compared to that obtained by the modified Newton-Raphson method. The GA approach is relatively expensive in terms of computing time and resources, and at present this limits the applicability of GA to the field of static imaging. However, the continuous and rapid growth of computing resources makes the development of real-time dynamic imaging applications based on GA´s conceivable in the near future.

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An NMR Study on Complexation of Ethylammonium Ion by Alkyl p-tert-Butylcalix[6]aryl Ester Derivatives

  • 안상두;문철순;정기주;이조웅;오원석;장석규
    • Bulletin of the Korean Chemical Society
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    • v.19 no.1
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    • pp.68-74
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    • 1998
  • The complexation of ethylammonium ion by alkyl p-tert-butylcalix[6]aryl ester derivatives was studied via measurements of proton and carbon spin-lattice relaxation times $(T_1)$ and chemical shift changes in solution state $(CDCl_3)$. The results indicate that the endo-type complexes are formed and that the overall tumbling rates of these complexes are more rapid than those of the corresponding free hosts. The association constants for these complexes in $THF-d_8$ were determined by $^1H$ NMR titration at several different temperatures to estimate the relevant thermodynamic parameters. The logK's for ethylammonium complexes of methyl, ethyl, and propyl esters at 313 K, for example, were found to be 1.56, 3.41, and 3.08, respectively. The complexes formed may be thought of as being kinetically stable in view of their $^1H$ NMR behavior in 2 : 1 host/guest solution.

A Study on the Development of Torsion Analysis Method for Buildings Using Rapid Safety Assessment System Based on Accelerometers (진동계측자료 기반 안전성평가 시스템을 활용한 건축물의 비틀림 분석 방법 개발)

  • Jeong, Seong-Hoon;Jang, Won-Seok;Lee, Jung-Han;Park, Byung-Cheol
    • Journal of the Earthquake Engineering Society of Korea
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    • v.25 no.6
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    • pp.275-281
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    • 2021
  • In this study, algorithms for analyzing the torsion of buildings under earthquake excitation are developed. The algorithm and formulations to account for the torsional angle are verified by analyzing the seismic acceleration time history data. The method was applied to the reference buildings to examine their operation and usability. The reference application demonstrated that the noise-canceling scheme successfully overcame various obstacles in the field measurements. The developed method is expected to be used as a tool to support a loss assessment system for determining the direction and priority of disaster response in the event of an earthquake.

Lipid Specificity for Membrane Oxidation Catalyzed by Cytochrome c : An EPR Study

  • 민동필;한상화
    • Bulletin of the Korean Chemical Society
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    • v.17 no.3
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    • pp.279-284
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    • 1996
  • Decay of the spin label attached to cytochrome c or to stearic acid has been measured by electron paramagnetic resonance (EPR) spectroscopy to monitor membrane oxidation induced by cytochrome c-membrane interaction. Binding of cytochrome c sequestered the acidic phospholipids and membrane oxidation was efficient in the order linoleic oleic>stearic acid for a fatty acid chain in the acidic phospholipids. The spin label on cyt c was destroyed at pH 7 whereas that on stearic acid embedded in the membrane was destroyed at pH 4, presumably due to different modes of cyt c-membrane interaction depending on pH. Interestingly, cyt c also interacts with phosphatidylethanolamine, an electrically neutral phospholipid, to cause rapid membrane oxidation. Both EPR and fluorescence measurements indicated that electrostatic interaction is at least partially responsible for the process.

Correction of late adolescent skeletal Class III using the Alt-RAMEC protocol and skeletal anchorage

  • Muhammed Hilmi Buyukcavus;Omer Faruk Sari;Yavuz Findik
    • The korean journal of orthodontics
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    • v.53 no.1
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    • pp.54-64
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    • 2023
  • This case report describes skeletal anchorage-supported maxillary protraction performed with the Alternate Rapid Maxillary Expansion and Constriction (AltRAMEC) protocol over a treatment duration of 14 months in a 16-year-old female patient who was in the late growth-development period. Miniplates were applied to the patient's aperture piriformis area to apply force from the protraction appliance. After 9 weeks of following the Alt-RAMEC protocol, miniplates were used to transfer a unilateral 500-g protraction force to a Petit-type face mask. A significant improvement was observed in the soft tissue profile in measurements made both cephalometrically and in three dimensional photographs. Subsequently, the second phase of fixed orthodontic treatment was started and the treatment was completed with the retention phase. Following treatment completion, occlusion, smile esthetics, and soft tissue profile improved significantly in response to orthopedic and orthodontic treatment.

Transitional Dark Energy - A solution to the H0 tension

  • Keeley, Ryan
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.59.2-59.2
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    • 2019
  • In this talk, I will explain the implications of a rapid appearance of dark energy between the redshifts ($z$) of one and two on the expansion rate and growth of perturbations. Using both Gaussian process regression and a parametric model, I show that this is the preferred solution to the current set of low-redshift ($z<3$) distance measurements if $H_0=73~\rm km\,s^{-1}\,Mpc^{-1}$ to within 1\% and the high-redshift expansion history is unchanged from the $\Lambda$CDM inference by the Planck satellite. Dark energy was effectively non-existent around $z=2$, but its density is close to the $\Lambda$CDM model value today, with an equation of state greater than $-1$ at $z<0.5$. If sources of clustering other than matter are negligible, we show that this expansion history leads to slower growth of perturbations at $z<1$, compared to $\Lambda$CDM, that is measurable by upcoming surveys and can alleviate the $\sigma_8$ tension between the Planck CMB temperature and low-redshift probes of the large-scale structure.

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Unusual Applications of Kendrick Plots: Recalibration and Tolerance

  • Thierry N. J. Fouquet;Orlando Cabarcos
    • Mass Spectrometry Letters
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    • v.14 no.4
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    • pp.173-177
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    • 2023
  • Kendrick plots offer an alternative visualization of mass spectral data which reveals ion series and patterning by turning a mass spectrum into a map, plotting the fractional mass (wrongly called mass defect) as a function of mass-to-charge ratios and ion abundances. Although routinely used for polymer mass spectrometry, two unreported applications of these Kendrick plots are proposed using the program "kendo2": the graphical recalibration of a mass spectrum via the simulation of a theoretical fractional mass and a multi-segment fit; and the rapid evaluation of scan-to-scan variation of accurate mass measurements used as tolerances for the blank subtraction of UPLC-MS data files. Both applications are compatible with any type of high-resolution MS data including LC/GC-MS(/MS).

Photocatalytic Degradation and Adsorptive Removal of Tetracycline on Amine-Functionalized Graphene Oxide/ZnO Nanocomposites

  • Thanh Truong Dang;Hoai-Thanh Vuong;Sung Gu Kang;Jin Suk Chung
    • Korean Chemical Engineering Research
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    • v.61 no.4
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    • pp.635-644
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    • 2023
  • Due to the rapid development of the livestock industry, particularly due to residual pharmaceutical antibiotics, environmental populations have been negatively affected. Herein, we report a ZnO/melamine-functionalized carboxylic-rich graphene oxide (ZFG) photocatalyst for visible light-driven photocatalytic degradation of tetracycline hydrochloride in aqueous solutions. The properties of the photocatalysts were evaluated by XRD, FTIR, XPS, Fe-SEM, HR-TEM, TGA, Raman spectroscopy, UV-Vis spectroscopy, zeta potential, and electrochemical measurements. The photocatalytic activity was measured using high-performance liquid chromatography. The photocatalytic properties of the ZFG photocatalyst evaluated against the tetracycline hydrochloride (TCH) antibiotic under visible light irradiation showed superior photodegradation of 96.27% within 60 min at an initial pH of 11. The enhancement of photocatalytic degradation was due to the introduction of functionalized graphene, which increases the light-harvesting capability and molecular adsorption capability in addition to minimizing the recombination rate of photogenerated charge carriers due to its role as an electron acceptor and mediator.