• 대한후두음성언어의학회지
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• 제10권2호
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• pp.154-163
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• 1999

GRBAS scale, the tool fir the perceptual evaluation of voice, demands the experience of judges, and MDVP parameters of CSL, the tool for the objective measurements of voice quality demands the exact interpretation of the analyzed results. The two tools should be used as compensatory evaluation methods, so the experimental study was performed to investigate the correlation between GRBAS scales and MDVP parameters by using the pathologic voice of the 30 patients with vocal polyps, and to know the significant MDVP parameters which the inexperienced GRBAS scale judges should attend to. The 30 subjects voices, saved in MDVP of CSL were analyzed by its own analysis program, and three experienced voice therapists judged the same voices by using GRBAS scales. The correlations between them were analyzed by Spearman Rank Correlation Coefficient. As results, among the 29 MDVP parameters, 22 parameters showed statistically significant correlation with Grade(G) scale(p＜0.05). And it was found that Roughness(R) scale showed significant correlation with 18 parameters, Breathiness(B) scale with 17 parameters, Strain(S) scale with 12 parameters. In Asthenicity(A) scale, no parameter showed significant correlation. On the whole, significantly high correlation were found in the parameters related with pitch ind amplitude perturbation, especially, the amplitude perturbation.

• 대한화장품학회지
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• 제25권2호
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• pp.129-138
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• 1999

피부 전용 제재 개발을 위해 요구되는 동물 대체 시험법 중 가장 적극적으로 연구가 행하여지곤 실제 실용화가 예상되는 것은 안점막 자극 시험으로 지금까지 여러 가지 방법이 개발되었지만 그 중 계란 유정란의 응모요막(CAM)을 이용한 방법이 현재 가장 활발히 진행되고 있다. 이 방법이 일부 국가에서 이미 안점막 자극 시험 동물 대체 시험법으로 공인되었으며 현재까지도 validation 연구를 활발히 진행하고 있다. 본 연구에서도 국내에 적합한 안점막 자극 시험 동물 대체 시험법의 공인 시험법 개발 및 validation study를 목표로 계란 유정란의 응모요막을 이용한 방법 중 HET-CAM 방법을 시행하였으며 안점막 동물 대체 시험법으로 확립하고자 하였다. 틴ET-CAM 방법의 보완을 위해 배양된 세포를 통해 자극도를 측정할 수 있는 방법인 Cytotoxicity test를 도입하여 시행하였으며 두 방법의 data들을 분석하여 validation study를 수행하였다. 국내 유수의 6개 장업사가 본 연구에 참가하여 20가지의 화장품 전용제재를 대상으로 1차, 2차 validation study 를 진행하였다. HET-CAM test, Draize eye irritation test, Cytotoxicity test 측정 결과 HET-CAM 의 “Q” 수치는 대부분 강자극 수치인 2 이상이었고 10% sodium hydroxide가 가장 높은 수치를 보였으며 Tween 20(sorbitanpolyoxyethylene monolaurate) 100%가 가장 낮은 수치를 보였다. In vi패의 경우 10% sodium hydroxide가 가장 높은 수치를 보였으며 30군 propylene glycol 이 가장 낮은 자극수치를 보였다. HET-CAM test 와 Draize eye irritation test, Cytotoxicity test 간의 상관성 분석은 linear correlation coefficient 와 rank correlation coefficient를 구하여 비교하였으며 6개 장업사(A-F)의 실험실에서의 HET-CAM test 결과를 취합하여 각각 두 실험실간의 상관관계(linear correlation)를 분석하였다. Linear correlation coefficient 분석 결과를 보면 전반적으로 상관관계가 0.589 - 0.954의 범위였으며, 특히 A사와 B사 사이의 경우 0.954이었으며, E사와 D사 사이의 경우 0.942로 높은 상관관계를 보였다. 그 외에도 A사와 D사 사이의 경우(0.589)와 B사와 D사 사이의 경우(0.638)를 제외하고는 대체로 높은 상관관계를 나타내었다.

• Korean Journal of Radiology
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• 제22권2호
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• pp.243-252
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• 2021

Objective: To compare and correlate the findings of intravoxel incoherent motion (IVIM) magnetic resonance (MR) imaging and arterial spin labeling (ASL) imaging in characterizing parotid gland tumors. Materials and Methods: We retrospectively reviewed 56 patients with parotid gland tumors evaluated by MR imaging. The true diffusion coefficient (D), pseudo-diffusion coefficient (D^*), and fraction of perfusion (f) values of IVIM imaging and tumor-to-parotid gland signal intensity ratio (SIR) on ASL imaging were calculated. Spearman rank correlation coefficient, chi-squared, Mann-Whitney U, and Kruskal-Wallis tests with the post-hoc Dunn-Bonferroni method and receiver operating characteristic curve assessments were used for statistical analysis. Results: Malignant parotid gland tumors showed significantly lower D than benign tumors (p = 0.019). Within subgroup analyses, pleomorphic adenomas (PAs) showed significantly higher D than malignant tumors (MTs) and Warthin's tumors (WTs) (p < 0.001). The D^* of WTs was significantly higher than that of PAs (p = 0.031). The f and SIR on ASL imaging of WTs were significantly higher than those of MTs and PAs (p < 0.05). Significantly positive correlation was found between SIR on ASL imaging and f (r = 0.446, p = 0.001). In comparison with f, SIR on ASL imaging showed a higher area under curve (0.853 vs. 0.891) in discriminating MTs from WTs, although the difference was not significant (p = 0.720). Conclusion: IVIM and ASL imaging could help differentiate parotid gland tumors. SIR on ASL imaging showed a significantly positive correlation with f. ASL imaging might hold potential to improve the ability to discriminate MTs from WTs.

• 재활치료과학
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• 제11권2호
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• pp.53-62
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• 2022

목적 : 본 연구는 뇌졸중 환자를 대상으로 한 인지기능 평가 도구 간의 상관성을 알아봄으로써 임상에서 평가 도구를 선정하거나 사용하는데 도움이 될 수 있는 기초자료를 제공하고자 하였다. 연구방법 : 본 연구는 병원 등 의료기관에 입원하여 작업치료를 받는 뇌졸중 환자 51명을 대상으로 실시하였다. 평가 도구는 인지선별검사(Cognitive Impairment Screening Test: CIST), 한국판 간이정신상태검사 2판(Korean-Mini Mental State Examination, 2nd Edition: K-MMSE~2)과 임상치매척도(Clinical Dementia Rating: CDR)를 사용하였다. 평가 도구 점수 간 상관관계는 Spearman's rank correlation coefficient를, 전체 CDR 점수에 따른 CIST와 K-MMSE~2의 총점 비교는 Wilcoxon signed rank test를 이용하여 분석하였다. 결과 : CIST와 K-MMSE~2의 총점 및 전체 CDR 점수 간 상관관계는 CIST와 K-MMSE~2(ρ=.956), CIST와 CDR(ρ=-.957), K-MMSE~2와 CDR(ρ=-.971)에서 통계학적으로 유의미한 상관관계를 보였다(p<.01). CIST와 K-MMSE~2의 하위영역별 점수 간 상관관계는 모든 하위영역에서 통계학적으로 유의미한 상관관계를 보였다(p<.01). 전체 CDR 점수에 따른 CIST와 K-MMSE~2의 총점 비교는 모든 전체 CDR 점수에서 통계학적으로 유의미한 차이를 보이지 않았다(p>.05). 결론 : 본 연구를 통해 뇌졸중 환자를 대상으로 한 CIST, K-MMSE~2 및 CDR 간에 상관성이 있다는 점을 알 수 있었다. 향후에는 다른 대상자를 통한 연구가 진행되기를 바라며, 본 연구의 결과가 병원 등의 임상에서 인지기능 평가 도구를 선정 또는 사용함에 있어 참고자료로 활용되기를 기대한다.

• Structural Engineering and Mechanics
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• 제42권2호
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• pp.229-245
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• 2012

Bridge vibration displacements have been directly measured by LVDTs (Linear Variable Differential Transformers) or laser equipment and have also been indirectly estimated by an algorithm of integrating measured acceleration. However, LVDT measurement cannot be applied for a bridge crossing over a river or channel and the laser technique cannot be applied when the weather condition is poor. Also, double integration of accelerations may cause serious numerical deviation if the initial condition or a regression process is not carefully controlled. This paper presents an algorithm of estimating bridge vibration displacements using vibration strains measured by FBG (Fiber Bragg Grating) sensors and theoretical mode shapes of a simply supported beam. Since theoretically defined mode shapes are applied, even high modes can be used regardless of the quality of the measured data. In the proposed algorithm, the number of theoretical modes is limited by the number of sensors used for a field test to prevent a mathematical rank deficiency from occurring in computing vibration displacements.89The proposed algorithm has been applied to various types of bridges and its efficacy has been verified. The closeness of the estimated vibration displacements to measured ones has been evaluated by computing the correlation coefficient and by comparing FRFs (Frequency Response Functions) and the maximum displacements.

• Journal of Astronomy and Space Sciences
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• 제30권3호
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• pp.163-168
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• 2013

Parameters associated with solar minimum have been studied to relate them to solar activity at solar maximum so that one could possibly predict behaviors of an upcoming solar cycle. The number of active days has been known as a reliable indicator of solar activity around solar minimum. Active days are days with sunspots reported on the solar disk. In this work, we have explored the relationship between the sunspot numbers at solar maximum and the characteristics of the monthly number of active days. Specifically, we have statistically examined how the maximum monthly sunspot number of a given solar cycle is correlated with the slope of the linear relationship between monthly sunspot numbers and the monthly number of active days for the corresponding solar cycle. We have calculated the linear correlation coefficient r and the Spearman rank-order correlation coefficient $r_s$ for data sets prepared under various conditions. Even though marginal correlations are found, they turn out to be insufficiently significant (r ~ 0.3). Nonetheless, we have confirmed that the slope of the linear relationship between monthly sunspot numbers and the monthly number of active days is less steep when solar cycles belonging to the "Modern Maximum" are considered compared with rests of solar cycles. We conclude, therefore, that the slope of the linear relationship between monthly sunspot numbers and the monthly number of active days is indeed dependent on the solar activity at its maxima, but that this simple relationship should be insufficient as a valid method to predict the following solar activity amplitude.

• Asian Pacific Journal of Cancer Prevention
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• 제16권1호
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• pp.355-361
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• 2015

Background: Deletion types of genetic variants of glutathione S-transferase (GST) M1 and T1, the GSTM1 null and GSTT1 null which are risk factors for certain cancers, have been ubiquitously found in human populations but their worldwide distribution pattern is unclear. Materials and Methods: To perform a meta-analysis, a systematic search for the literature on GSTM1 and GSTT1 null genotypes was done to identify 63 reports for 81 human populations. Relationships between the GSTM1 and GSTT1 null genotype frequencies and the absolute latitude of 81 populations were tested by Spearman's rank correlation coefficient. Results: A significant positive correlation was detected between the GSTM1 null genotype frequency and the absolute latitude (r=0.28, p-value <0.05), whereas the GSTT1 null genotype frequency and absolute latitude showed a significant negative correlation (r= -0.41 p-value <0.01). There was no correlation between the frequencies of GSTM1 and GSTT1 null genotype in each population (r= -0.029, p-value=0.80). Conclusions: Latitudinal clines of the distribution of the GSTM1 and GSTT1 null genotypes may be attributed to the result of gene-environmental adaptation. No functional compensation between GSTM1 and GSTT1 was suggested by the lack of correlation between the null frequencies for GSTM1 and GSTT1.

• 한국전문물리치료학회지
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• 제4권3호
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• pp.45-60
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• 1997

This study was performed to determine the inter-rater reliability of the Chedoke-McMaster Stroke Assessment translated in Korean. This measures the physical impairments and disabilities that impact on the lives of individuals with stroke. The purposes of this measure were 1) to stage motor recovery to classify individuals in terms of clinical characteristics, 2) to predict rehabilitation outcomes, and 3) to measure clinically important change in physical function. Twenty-two subjects from physical therapy unit were assessed by two physical therapists. The ratings were compared by Spearman's rank correlation The correlation between two raters ranged from 0.85 to 0.98. Inter-rater reliability coefficient for total scores ranged from 0.95 to 0.97. This study confirms that the Chedoke-McMaster Stroke Assessment yields reliable results.

• Journal of the Korean Data and Information Science Society
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• 제23권6호
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• pp.1065-1074
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• 2012

한국 프로야구에서 출루 능력과 장타력이 득점 생산성에 미치는 영향을 통계적으로 분석하였다. 2절에서는 OPS (On-base percentage Plus Slugging average)에 관하여 고찰하고 그것을 변형한 새로운 타격지표들을 소개하였다. 3절에서는 2007년부터 2011년까지의 정규리그 전 경기 자료를 바탕으로 타율, 출루율, 장타율, IsoP (Isolated Power), OPS 및 2절에서 소개된 지표들이 팀의 경기당 평균득점과 갖는 상관관계를 알아보았다. 또한 OPS와 2절에서 소개된 지표들을 일반화하여 여러 가지 가중값을 갖는 타격지표들이 팀의 경기당 평균득점과 갖는 상관관계를 분석하였다. 그 결과 출루율에 57%, 장타율에 43%의 가중값을 주는 가중OPS가 득점 생산성을 가장 잘 설명하는 타격지표인 것으로 밝혀졌다.

• 한국보건간호학회지
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• 제23권1호
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• pp.17-26
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• 2009

Purpose: In this study, the effects of an alcohol education program for elderly persons with drinking problems and the effects of knowledge of the behavior associated with alcohol use by elderly individuals with drinking problems were evaluated. Method: A single-group repeated study was conducted to evaluate 19 elderly individuals with drinking problems who used the G-city Elderly Welfare Center, with more than eight points in AUDIT results. The changes in drinking knowledge and alcohol behavior following an alcohol education program were evaluated. The effectiveness of the program was analyzed by a Wilcoxon signed rank test. and the relationship between drinking knowledge and changes in alcohol behavior was measured by Spearman's rank correlation coefficient. Results: The results indicated that drinking knowledge after conducting education increased significantly(Z=-3.826, p<.001), and that this increased knowledge resulted in significant changes in alcohol behavior(Z=-3.830, p<.001). There was a significantly positive relationship between drinking knowledge and changes in alcohol behavior(r=.464, p=0.013). Conclusion: Alcohol education programs effectively educate the elderly with drinking problems regarding alcohol, which influences their alcohol behavior.