• Title/Summary/Keyword: rank analysis

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Analysis of the Characteristics of Biophilic Design in 『Soswaewon 48 Yeong』 (『소쇄원 48영』에 나타난 바이오필릭 디자인 특성분석)

  • Lee, Hyung-Sook;Choi, Mi-Seon
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.40 no.4
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    • pp.58-66
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    • 2022
  • Biophilic design is an approach that attempts to connect people with nature to promote health, recovery and restoration processes. The purpose of this study was to systematically analyze restorative factors and characteristics of Soswaewon by applying a biophilic design analysis framework. To this end, a biophilic design classification system was established and content analysis and frequency analysis were conducted for 『Soswaewon 48 Young』. the ratio of plant words including bamboo, pine, and plum was the highest, and words related to dynamic water flow or interaction with water as well as various water types such as streams, waterfalls, and ponds were also high. appeared in rank. In addition, multisensory factors, seasonal changes, microclimatic factors, emotional elements that allow people to indirectly experience nature were expressed in various ways. The space layout and circulation provide opportunities to appreciate and experience the rich sensory resources of Soswaewon. In conclusion, this study confirmed the healing and restorative value of Soswaewon from the perspective of biophilic design, and it needs further research on the restorative factors of traditional spaces.

Prognostic Value of 18F-FDG PET/CT Radiomics in Extranodal Nasal-Type NK/T Cell Lymphoma

  • Yu Luo;Zhun Huang;Zihan Gao;Bingbing Wang;Yanwei Zhang;Yan Bai;Qingxia Wu;Meiyun Wang
    • Korean Journal of Radiology
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    • v.25 no.2
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    • pp.189-198
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    • 2024
  • Objective: To investigate the prognostic utility of radiomics features extracted from 18F-fluorodeoxyglucose (FDG) PET/CT combined with clinical factors and metabolic parameters in predicting progression-free survival (PFS) and overall survival (OS) in individuals diagnosed with extranodal nasal-type NK/T cell lymphoma (ENKTCL). Materials and Methods: A total of 126 adults with ENKTCL who underwent 18F-FDG PET/CT examination before treatment were retrospectively included and randomly divided into training (n = 88) and validation cohorts (n = 38) at a ratio of 7:3. Least absolute shrinkage and selection operation Cox regression analysis was used to select the best radiomics features and calculate each patient's radiomics scores (RadPFS and RadOS). Kaplan-Meier curve and Log-rank test were used to compare survival between patient groups risk-stratified by the radiomics scores. Various models to predict PFS and OS were constructed, including clinical, metabolic, clinical + metabolic, and clinical + metabolic + radiomics models. The discriminative ability of each model was evaluated using Harrell's C index. The performance of each model in predicting PFS and OS for 1-, 3-, and 5-years was evaluated using the time-dependent receiver operating characteristic (ROC) curve. Results: Kaplan-Meier curve analysis demonstrated that the radiomics scores effectively identified high- and low-risk patients (all P < 0.05). Multivariable Cox analysis showed that the Ann Arbor stage, maximum standardized uptake value (SUVmax), and RadPFS were independent risk factors associated with PFS. Further, β2-microglobulin, Eastern Cooperative Oncology Group performance status score, SUVmax, and RadOS were independent risk factors for OS. The clinical + metabolic + radiomics model exhibited the greatest discriminative ability for both PFS (Harrell's C-index: 0.805 in the validation cohort) and OS (Harrell's C-index: 0.833 in the validation cohort). The time-dependent ROC analysis indicated that the clinical + metabolic + radiomics model had the best predictive performance. Conclusion: The PET/CT-based clinical + metabolic + radiomics model can enhance prognostication among patients with ENKTCL and may be a non-invasive and efficient risk stratification tool for clinical practice.

Prognostic Value of Dynamic Contrast-Enhanced MRI-Derived Pharmacokinetic Variables in Glioblastoma Patients: Analysis of Contrast-Enhancing Lesions and Non-Enhancing T2 High-Signal Intensity Lesions

  • Yeonah Kang;Eun Kyoung Hong;Jung Hyo Rhim;Roh-Eul Yoo;Koung Mi Kang;Tae Jin Yun;Ji-Hoon Kim;Chul-Ho Sohn;Sun-Won Park;Seung Hong Choi
    • Korean Journal of Radiology
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    • v.21 no.6
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    • pp.707-716
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    • 2020
  • Objective: To evaluate pharmacokinetic variables from contrast-enhancing lesions (CELs) and non-enhancing T2 high signal intensity lesions (NE-T2HSILs) on dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging for predicting progression-free survival (PFS) in glioblastoma (GBM) patients. Materials and Methods: Sixty-four GBM patients who had undergone preoperative DCE MR imaging and received standard treatment were retrospectively included. We analyzed the pharmacokinetic variables of the volume transfer constant (Ktrans) and volume fraction of extravascular extracellular space within the CEL and NE-T2HSIL of the entire tumor. Univariate and multivariate Cox regression analyses were performed using preoperative clinical characteristics, pharmacokinetic variables of DCE MR imaging, and postoperative molecular biomarkers to predict PFS. Results: The increased mean Ktrans of the CEL, increased 95th percentile Ktrans of the CELs, and absence of methylated O6-methylguanine-DNA methyltransferase promoter were relevant adverse variables for PFS in the univariate analysis (p = 0.041, p = 0.032, and p = 0.083, respectively). The Kaplan-Meier survival curves demonstrated that PFS was significantly shorter in patients with a mean Ktrans of the CEL > 0.068 and 95th percentile Ktrans of the CEL > 0.223 (log-rank p = 0.038 and p = 0.041, respectively). However, only mean Ktrans of the CEL was significantly associated with PFS (p = 0.024; hazard ratio, 553.08; 95% confidence interval, 2.27-134756.74) in the multivariate Cox proportional hazard analysis. None of the pharmacokinetic variables from NE-T2HSILs were significantly related to PFS. Conclusion: Among the pharmacokinetic variables extracted from CELs and NE-T2HSILs on preoperative DCE MR imaging, the mean Ktrans of CELs exhibits potential as a useful imaging predictor of PFS in GBM patients.

A Content Analysis of the Advocacy Concept Perceived by Nurses at Nursery Room (옹호개념에 관한 신생아실 간호사의 인지 내용 분석)

  • Cho Kap Chul
    • Child Health Nursing Research
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    • v.2 no.1
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    • pp.13-26
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    • 1996
  • This descriptive study was done to detect the possibilities of the development of the advocacy concept in nursing. The subjects consisted of 3 nurses who had agreed to participate to the study, working at nursery room in a general hospital. Data was collected from May 22 to June 13 in 1995 through tape recorded intensive-interview, and written down, then content analyzed qualitatively related to the infant advocacy. 1. Derivation fo the meaning about advocacy concept 1) The situations in need of infant advocacy were 12 categories : malpractice, overcharing, negligence, unnecessary services, and services without consent, and so on. 2) Fourteen categories of advocacy activities percived by nurses were derived from participants' statements. Protesting infant or his /her families against their counterpart, providing informations to families, cooperating with medical staffs for her patient, then calling medical staff not so as to be maleficient to her patient in its rank. 3) The expected result of advocacy activities perceived by nurses was respectively positive to her patient or families, but negative to nurse. 4) The feelings of nurses in the sitution of advocacy were expressed in to concern, comprehension, regret, powerlessness, charity, desire, and so on. 5) Nurses perceived that advocacy activities could be influenced positively by factors related to nurses' qualification and negatively by factors related to doctor's overdo and nurse's underdo. 2. Categorization of the meaning and their relationships In case of antecedental situation in need of infant advocacy, nurse perceives her patients need the advocacy to get a benefit through nurse's information, intervention speaking, building cooperations. The expected factors to influence advocacy activities perceived by nurses, are the power imbalance between medical staffs, the nurse's qualification, and the nurse's feeling from the situation. The above results suggest that the infant care situation will be recommendable field work place for concept development of advocacy with hybride model when it involves infant's families.

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Development of a Reproducibility Index for cDNA Microarray Experiments

  • Kim, Byung-Soo;Rha, Sun-Young
    • Proceedings of the Korean Statistical Society Conference
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    • 2002.05a
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    • pp.79-83
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    • 2002
  • Since its introduction in 1995 by Schena et al. cDNA microarrays have been established as a potential tool for high-throughput analysis which allows the global monitoring of expression levels for thousands of genes simultaneously. One of the characteristics of the cDNA microarray data is that there is inherent noise even after the removal of systematic effects in the experiment. Therefore, replication is crucial to the microarray experiment. The assessment of reproducibility among replicates, however, has drawn little attention. Reproducibility may be assessed with several different endpoints along the process of data reduction of the microarray data. We define the reproducibility to be the degree with which replicate arrays duplicate each other. The aim of this note is to develop a novel measure of reproducibility among replicates in the cDNA microarray experiment based on the unprocessed data. Suppose we have p genes and n replicates in a microarray experiment. We first develop a measure of reproducibility between two replicates and generalize this concept for a measure of reproducibility of one replicate against the remaining n-1 replicates. We used the rank of the outcome variable and employed the concept of a measure of tracking in the blood pressure literature. We applied the reproducibility measure to two sets of microarray experiments in which one experiment was performed in a more homogeneous environment, resulting in validation of this novel method. The operational interpretation of this measure is clearer than Pearson's correlation coefficient which might be used as a crude measure of reproducibility of two replicates.

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A Study on the Visual Evaluation of the Gather Effect in Ruffle (Ruffle의 gather 효과에 대한 시각평가의 연구)

  • Kwon Young-Suk;Moon Meyng-Ok
    • Journal of the Korean Society of Clothing and Textiles
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    • v.11 no.1
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    • pp.43-49
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    • 1987
  • To study the visual evaluation on the effect of ruffle's gather, the aesthetic evaluation on the gather's measurements and the image evaluation were performed. Evaluated fabrics were cotton, wool ani synthetic fiber, and 3 kinds of thickness for each fabric were selected. In order to seek for aesthetic gather's measurements, we performed the sensory test by the Rank Method on 5 kinds of gather's measurements(I.5 times, 1. 8times, 2times, 2.5 times, 3 times). For the image evaluation on the effect of the gather, we performed the sensory test by the Semantic Differential Method on the gather's measurements were got high score in the sensory test of the gather's measurements and analyzed by means of a Factor Analysis. The results were as follows. 1. Except 2 times of fabric $A_1$(thin cotton), the aesthetic gather's measurements of the ruffle were evaluted 2.5 times in cotton and synthetic fiber, and 2 times in wool. Generally the aesthetic gather's measurements of the ruffle were 2$\~$2.5 times. 2. The image characteristics of the ruffle were established the characteristics of the fabrics as factor 1, the characteristics of the atomosphere as factor 2 and the characteristics of the drape as factor 3. Therefore, we must consider the characteristics of the fabric, the atomosphere and the drape of the ruffle in production of the ruffle.

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Fuzzy TOPSIS Approach to Flood Vulnerability Assessment in Korea (우리나라 홍수 취약성 평가를 위한 Fuzzy TOPSIS 접근법)

  • Kim, Yeong-Kyu;Chung, Eun-Sung;Lee, Kil-Seong
    • Journal of Korea Water Resources Association
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    • v.45 no.9
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    • pp.901-913
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    • 2012
  • This study will be a new attempt to quantify flood vulnerability taking into account uncertainty. Information obtained from the real world has lots of uncertainties. Therefore, this study developed an approach to quantify spatial flood vulnerability of Korea using Fuzzy TOPSIS approach. Also, Fuzzy TOPSIS were compared with TOPSIS and weighted sum method. As a result, rankings of some areas were changed dramatically due to the uncertainty. Spearman rank correlation analysis indicated that the rankings of TOPSIS and weighted sum method were almost similar, but quite different from ranking of Fuzzy TOPSIS. In other words, because applying Fuzzy concept in regional vulnerability assessment may cause a significant change in priorities, the model presented in this study may be a method of vulnerability assessment.

A Study on the Effect of Golf Driver Head Speed and Back Muscular Strength in TBA-G of FCST (FCST 원리를 적용한 TBA-G의 골프 드라이버 헤드 속도와 배근력 영향에 대한 연구)

  • Sun, Seung-Ho;Park, Chang-Woon;Jung, Hye-Jung;Ahn, Seung-Hun;Sohn, In-Chul;Lee, Young-Jun
    • The Journal of Korean Medicine
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    • v.34 no.1
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    • pp.80-88
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    • 2013
  • Objectives: The purpose of this study was to examine the effect of Temporomandibular joint Balance Appliance for Golf (TBA-G) of Functional Cerebrospinal Therapy (FCST) on golf driver head speed and back muscle power. Methods: Twenty-one participants that had a golf career of 4 years or more were involved. We measured golf drive head speed and back muscular strength before and after applying TBA-G in the mouth. A paired t test or Wilcoxon singed rank test was performed to identify the difference of effect between before and after applying TBA-G, using IBM SPSS 19.0. We considered difference significant at P<0.05. Results: Driver head speed increased significantly by 2 mph (1.99%) after applying TBA-G [from $100.52{\pm}9.82$ mph ($mean{\pm}SD$) to $102.52{\pm}10.43$ mph, P<0.001]. Back muscular strength also increased by 7.28 kg (5.60%) [from $129.90{\pm}28.31$ kg to $137.18{\pm}28.81$ kg, P<0.001]. In stratification analysis, a more significant increase was found in the drive head speed and back muscular strength of groups of males with weight more than 69kg, with height more than 175cm, and with golf experience more than 7 years, compared to those of other groups. Conclusions: The results suggest that TBA-G could improve golf drive head speed and back muscular strength.

A Study of Effect of Disability Prevention Program Acquired by People with Disabilities are Performed : centered on Elementary School Students (휠체어 장애인과 함께하는 장애예방교육의 융·복합 효과에 관한 연구 : 초등학생을 중심으로)

  • Kim, Yeon-Jung
    • Journal of Digital Convergence
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    • v.14 no.5
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    • pp.369-376
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    • 2016
  • The purpose of this study was to identify the effect the disability prevention program by spinal cord injury lecturer for elementary school students. 1,167 students participated and data were analyzed using Wilcoxon signed-rank test by SPSS 22.0 program and qualitative analysis. The disability prevention program was a 40minutes, program composed of cause of disability, watching cases of accidents, story of disabled lecturer. The result showed that there were significant improvements in self-efficacy(Z=-26.109, p<.01) and awareness for the disabled. This study suggests that the disability prevention program by disabled lecturer had a positive effect on elementary school students. So the program should be expanded for children.

A Model for Ranking Semantic Associations in a Social Network (소셜 네트워크에서 관계 랭킹 모델)

  • Oh, Sunju
    • The Journal of Society for e-Business Studies
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    • v.18 no.3
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    • pp.93-105
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    • 2013
  • Much Interest has focused on social network services such as Facebook and Twitter. Previous research conducted on social network often emphasized the architecture of the social network that is the existence of path between any objects on network and the centrality of the object in the network. However, studies on the semantic association in the network are rare. Studies on searching semantic associations between entities are necessary for future business enhancements. In this research, the ontology based social network analysis is performed. A new method to search and rank relation sequences that consist of several relations between entities is proposed. In addition, several heuristics to measure the strength of the relation sequences are proposed. To evaluate the proposed method, an experiment was performed. A group of social relationships among the university and organizations are constructed. Some social connections are searched using the proposed ranking method. The proposed method is expected to be used to search the association among entities in ontology based knowledge base.