• Asian Pacific Journal of Cancer Prevention
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• v.13 no.3
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• pp.1049-1052
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• 2012

The purpose of this study was to evaluate expression and prognostic value of matrix metalloproteinase-7 (MMP-7) in colorectal cancer (CRC) patients. CRC tissues and corresponding distal normal mucosa tissues of 118 CRC patients were assessed by immunohistochemistry. Correlations between MMP-7 expression, patients' clinic pathological features, and overall survival rate were analyzed. We found that positive expression of MMP-7 in CRC tissues was significantly higher than that in distal normal mucosa (61.0% vs. 39.8%, p =0.001). Poor histological differentiation, advanced clinical stage and lymph node metastasis were significantly correlated with MMP-7 expression in CRC. The overall survival rate was significantly higher in the MMP-7 negative group than the positive group (Log-rank test= 9.957, p= 0.002). MMP-7 appeared as a significant independent prognostic factor through multivariate survival analysis. Collectively, we found MMP-7 expression to be correlated with progression and metastasis of CRC and thus could be used as a predictive marker of prognosis in CRC patients.

• Fisheries and Aquatic Sciences
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• v.13 no.2
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• pp.157-166
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• 2010

We investigated the benthic polychaete assemblage in Gwangyang Bay and Yeosu Sound in February 1997. The sediment was an almost entirely muddy facies. The benthic macrofauna comprised 295 species occurring at a mean density of 875 $indiv./m^2$. Polychaetes were the major faunal component; there were 94 species at mean density 765 $indiv./m^2$. The highest abundance and species richness occurred in the Myodo south and north channels, in the mouth of Gwangyang Bay, and in the Noryang channel mouth. The most abundant polychaete was Tharyx sp. (47.9%), followed in rank order by Heteromastus filiformis (9.6%), Melinna cristata (9.3%), and Lumbrineris longifolia (7.3%). Cluster analysis divided the study area into four station groups based on station similarities in benthic polychaete assemblages: the Glycinde-Prionospio cluster in the western inner bay, the H. filiformis cluster in the middle inner bay, the Melinna-Lumbrineris cluster in the Myodo south-north channel, and the Tharyx cluster in the eastern main channel region. The sediment type of Gwangyang Bay has changed gradually from sandy to muddy. Dominant species have also changed from Chone teres and Lagis bocki to Tharyx sp., which is a potential organic pollution indicator.

• Korean Journal of Human Ecology
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• v.18 no.6
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• pp.1221-1235
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• 2009

The purpose of this study is to examine the infant-teacher interaction and its possible effects. The subjects of this study were 24 child-care teachers from Jungup City, Korea. Among them, 12 teachers participated m the program as an experimental group. The program processed 8 sessions in total, a session a week and 90 minutes for each session. The data was collected by questionnaires of infant-teacher interactions and videotapes of their linguistic and behavioral interactions between infants and teachers. The collected data was analyzed by t-tests, wilcoxon signed-rank tests, and video content analysis. As a result, the teachers in the experimental group showed more significant enhancement than teachers in the comparison group in relation to the post-test of positive linguistic interactions between infant and teacher and teacher' positive reaction.

• Journal of Korean Library and Information Science Society
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• v.41 no.4
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• pp.5-33
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• 2010

This study is intended to present methods improving the classification system of KDC education fields after comparing and analyzing the academic system of education, classification system of KDC, NDC, DDC and LCC, and that of the research field classification system of National Research Foundation of Korea. The results of the analysis have revealed that it is required to improve and correct the KDC 5th edition of education including the addition of classification items that reflect the trend of academic development, proper development in the rank classification terms of education detailed fields, addition of detailed subjects, errors of classification symbols and omission of correlative indexes in the classification items. This study has proposed improved methods to solve those problems.

• Journal of Construction Engineering and Project Management
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• v.3 no.4
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• pp.20-25
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• 2013

Variation in construction means modification of design, changes in quality, quantity of work including the alteration of standard of materials or goods to be used in the work and the removal from site any kind of material not in accordance in the contract. In Ghana, Variation order has become major issue in the construction industry. This had resulted in cost overruns, delay and in some contracts dispute, between parties. The aim of this paper was to identify the root causes of variation; effects of variations on projects in Ghana and the means of reducing the impact of variation order. The method of the study involved literature review, primary data collection, interview and closed - ended- questionnaires. Mean Scores Method was used to rank the identified factors causing variation. Analysis Of Variance Test was use to test for the significant difference between means among the professional groups. The study revealed that most causes of variation were change of design by client and inadequate working details. Establishment of oversight project management committee and flow of information were identified as means of controlling variations during project administration.

• Proceedings of the Korean Information Science Society Conference
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• 2006.06a
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• pp.13-15
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• 2006

microRNA는 유전자의 전사 후 과정에서 negative regulation을 담당하는 small noncoding RNA의 한 증류이다. 최근까지 330여개의 인간 microRNA가 발견되었지만 그들의 기능이 밝혀진 것은 소수에 불과하다. microRNA의 기능은 3'UTR에 불완전 상보결합을 통해 negative regulation을 받게 되는 유전자의 기능으로부터 유추되는 것이 일반적이다. 특별히 유전체상에 군집화 된 microRNA들은 하나의 전사체로부터 발현되는 것으로 판단되며, 같은 또는 관련된 기능을 하거나 같은 목표 유전자를 조절하기 위한 functional family일 가능성이 높다. 또한 이러한 functional family는 하나의 전사체로부터 발현되기 때문에, 조직별로 조건별로 같은 발현 패턴을 보여야 한다. 본 연구에서는 발현데이터로부터 microRNA functional family를 탐색하기 위해, 5개의 연구 그룹에서 공개한 조직별 microRNA 발현데이터를 표준화 작업을 거친 후 통합하고 k-nearest neighbor 알고리즘을 이용해 결측치를 보정한 후 microRNA 발현사이의 correlation을 계산한다. 이때 데이터 통합에서 생기는 문제에 robust한 결과를 얻기 위해 실제 발현데이터가 아닌 rank 데이터부터 correlation을 측정한다. 계산된 spearman ranked correlation 결과와 microRNA의 genomic coordination 정보로부터 34개의 functional family를 정의할 수 있었다.

• The Journal of Asian Finance, Economics and Business
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• v.7 no.7
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• pp.391-401
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• 2020

The objective of this study is to prioritize the Total Quality Management (TQM) factors based on fuzzy Analytical Hierarchy Process (AHP) method in Vietnamese supporting industries. Through an in-depth literature review, eight criteria were identified. These criteria were then divided into 32 sub-criteria. The fuzzy AHP is used to determine the percent weightings of eight categories of performance criteria that were identified via a review of the quality-management literature. These criteria include management commitment, role of the quality department, training and education, continuous improvement, quality policies, quality data and reporting, communication to improve quality, and customer satisfaction orientation. An empirical analysis of the criteria of each stage using the fuzzy AHP methodology and the expert opinion of quality management are used to evaluate the percent weightings of the criteria and sub-criteria that are synonymous with TQM implementation. The results showed that management commitment is the most critical factor; among sub-criteria, supports and responsibilities of top management is the most important. The study also identified the rank order of critical success factors of TQM. The findings suggest a generic hierarchy model for organizations to prioritize the critical factors and formulate strategies for implementing TQM in supporting industries, as well as other industries in Vietnam.

• Journal of Microbiology and Biotechnology
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• v.25 no.1
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• pp.1-10
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• 2015

The bacterial diversity of 10 marine sponges belonging to the species Cliona celata, an unidentified Cliona species, Haliclona cinerea, Halichondria okadai, Hymeniacidon sinapium, Lissodendoryx isodictyalis, Penares incrustans, Spirastrella abata, and Spirastrella panis collected from Jeju Island and Chuja Island was investigated using amplicon pyrosequencing of the 16S rRNA genes. The microbial diversity of these sponges has as of yet rarely or never been investigated. All sponges, except Cliona celata, Lissodendoryx isodictyalis, and Penares incrustans, showed simple bacterial diversity, in which one or two bacterial OTUs occupied more than 50% of the pyrosequencing reads and their OTU rank abundance curves saturated quickly. Most of the predominant OTUs belonged to Alpha-, Beta-, or Gammaproteobacteria. Some of the OTUs from the sponges with low diversity were distantly (88%~89%) or moderately (93%~97%) related to known sequences in the GenBank nucleotide database. Phylogenetic analysis showed that many of the representative sequences of the OTUs were related to the sequences originating from sponges and corals, and formed sponge-specific or -related clades. The marine sponges investigated herein harbored unexplored bacterial diversity, and further studies should be done to understand the microbes present in sponges.

• Journal of muscle and joint health
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• v.21 no.3
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• pp.165-172
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• 2014

Purpose: The purpose of this study was to identify effects of postural habits and stress on low back pain experienced by nursing students. Methods: The survey was conducted with 282 students at 5 nursing schools in Seoul, Incheon, Chungcheongbuk, and Jeollabuk Province. Data were collected from October, 2013 to January, 2014. Data analyses including descriptive analysis, ANOVA, Pearson's correlation coefficient, Spearman's rank correlation coefficients, and multiple regression were performed using SPSS 21.0. Results: In multiple regression, habit of standing on force of one feet (${\beta}=.23$, p<.001), habit of sleeping on one's back (${\beta}=-.19$, p=.020), habit of resting the chin on one's hands (${\beta}=.15$, p=.029), and habit of carrying a bag on one shoulder (${\beta}=.12$, p=.011) were associated with low back pain experienced by nursing students. These factors accounted for 12.9% of the variance in the low back pain in undergraduate students. Conclusion: These results suggest that low back pain in nursing students are related to their habits of posture in daily life. Therefore, intervention program to encourage healthy postural habits can be effective to prevent low back pain in nursing students.

• Journal of the Korean Society of Physical Medicine
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• v.6 no.2
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• pp.127-133
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• 2011

Purpose: 본 연구는 단하지 보조기를 사용하는 뇌졸중환자의 시-거리 보행변수에 대한 청각신호 효과에 대한 알아보고자 하는 것이다. Methods: 9명의 뇌졸중환자가 본 연구에 참여하였으며 대상자는 보조기 착용이 없는 경우, 기존 보조기 착용의 경우 그리고 청각신호 보조기 착용의 경우에 각각 시-거리 보행 변수에 대해 측정하였다. 8대의 동작분석 카메라 시스템(Motion Analysis Corporation, Santa Rosa, USA)을 사용하여 시-거리 보행 변수를 측정하였으며 Wilcoxon rank sum test을 이용하여 양하지의 대칭성을 분석하였고 Friedman test를 사용하여 다른 보조기 사용에 따른 효과를 알아보았다. Results: 청각 신호 보조기의 경우, 손상측과 비손상측의 보행속도, 활보장 그리고 분속수가 대칭적으로 되었다. 손상측의 경우, 단하지 보조기를 착용하였을 때가 착용하지 않았을 때보다 대체적으로 보행 변수들이 증가하였다. 청각 신호 단하지 보조기를 착용하였을 때 손상측 하지의 보행 속도, 활보장, 보장, 양하지 지지 시간이 증가하였고 단하지 지지 시간은 감소하였다. Conclusion: 청각 신호 단하지 보조기 착용 시 보행 속도, 활보장, 보장은 보조기를 착용하지 않았을 때보다는 증가하였으나 청각 신호 단하지 보조기와 기존 단하지 보조기 착용 사이에는 차이가 없었다. 하지만, 본 연구의 결과는 청각 신호 단하지 보조기가 뇌졸중 환자의 시-거리 보행 변수를 개선할 수 있음을 보여주었고 앞으로 다양한 보행 변수들에 대한 연구가 필요하다고 생각한다.