• Genomics & Informatics
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• v.4 no.2
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• pp.71-76
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• 2006

We have investigated biological responses to radiofrequency (RF) radiation in in vitro and in vivo models. By measuring the levels of heat shock proteins as well as the activation of mitogen activated protein kinases (MAPKs), we could not detect any differences upon RF exposure. In this study, we used more sensitive method to find the molecular responses to RF radiation. Jurkat, human T-Iymphocyte cells were exposed to 1763 MHz RF radiation at an average specific absorption rate (SAR) of 10 W/kg for one hour and harvested immediately (R0) or after five hours (R5). From the profiles of 30,000 genes, we selected 68 differentially expressed genes among sham (S), R0 and R5 groups using a random-variance F-test. Especially 45 annotated genes were related to metabolism, apoptosis or transcription regulation. Based on support vector machine (SVM) algorithm, we designed prediction model using 68 genes to discriminate three groups. Our prediction model could predict the target class of 19 among 20 examples exactly (95% accuracy). From these data, we could select the 68 biomarkers to predict the RF radiation exposure with high accuracy, which might need to be validated in in vivo models.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.37 no.6
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• pp.586-594
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• 2009

This paper is the study on random, sinusoidal and shock vibration responses for the STSAT-3(science and technology satellite-3) proto-model which is the first small size all-composite satellite in Korea. The structure system of the STSAT-3 forms box type structure by joining several hybrid sandwich panels comprised of honeycomb core and carbon fiber reinforced laminated composite skins on both side. Mode shape, stress, displacement and acceleration responses are obtained on both the frequency domain and time domain by means of a commercial FEA software MSC/NASTRAN. From these analysis results, failure, safety factor and design validity are assessed. These results can be successfully applicable as reference data when a new satellite is developed as well as giving out an excellent criteria in satellite vibration treatment design.

• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.2 s.54
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• pp.81-94
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• 2007

In most experimental researches on the liquefaction phenomenon, an earthquake as a random vibration has been regraded as a sinusoidal wave or a triangular wave with an equivalent amplitude. Together with the development in the part of signal control and data acquisition, dynamic experimental equipments in the soil dynamics have also developed rapidly and further more, several real earthquakes have been simulated in the large model test such as shaking table tests and centrifuge tests. In Korea, several elementary laboratory tests to simulate the real earthquake load were performed. From these test results, it was reported that the sinusoidal wave cannot reliably reflect the soil dynamic behavior under the real earthquake motion. In this study, 4 types of dynamic motions such as the sinusoidal wave, the triangular wave, the incremental triangular wave and several real earthquake motions which were classified with shock-type and vibration-type were loaded to find something new to explain the change of the excess pore water pressure under the real earthquake load. Through the detailed investigation and comparison on all test results, it is found that the dynamic flow is generated by the soil plastic deformation and the velocity head of dynamic flow is changed the pressure head in the un-drained condition. It can be concluded that the change of the excess pore water pressure is related to the pressure head of dynamic flow. Lastly, a new hypothesis to explain such a liquefaction initiation phenomenon under the real earthquake load is also proposed and verified.