• Industrial Engineering and Management Systems
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• 제16권1호
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• pp.64-79
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• 2017

Identifying disease genes from human genome is a critical task in biomedical research. Important biological features to distinguish the disease genes from the non-disease genes have been mainly selected based on traditional feature selection approaches. However, the traditional feature selection approaches unnecessarily consider many unimportant biological features. As a result, although some of the existing classification techniques have been applied to disease gene identification, the prediction performance was not satisfactory. A small set of the most important biological features can enhance the accuracy of disease gene identification, as well as provide potentially useful knowledge for biologists or clinicians, who can further investigate the selected biological features as well as the potential disease genes. In this paper, we propose a new stepwise random forests (SRF) approach for biological feature selection and disease gene identification. The SRF approach consists of two stages. In the first stage, only important biological features are iteratively selected in a forward selection manner based on one-dimensional random forest regression, where the updated residual vector is considered as the current response vector. We can then determine a small set of important biological features. In the second stage, random forests classification with regard to the selected biological features is applied to identify disease genes. Our extensive experiments show that the proposed SRF approach outperforms the existing feature selection and classification techniques in terms of biological feature selection and disease gene identification.

• 한국정보처리학회논문지
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• 제4권2호
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• pp.515-522
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• 1997

컴퓨터 통신망에서 안정된 프로토콜을 제공하기 위해 분산된 큐를 이용한 임의 접근 프로토콜(Distributed Queuing Random Acess Protocol:DQRAP)을 제안하고 검토한다. DQRAP 프로토콜은 통신망에서 노드간의 경쟁을 해소하고 메시지 전송을 스케줄하기 위해 미니 슬롯을 사용해서 채널 피드백과 두 개의 분산 큐를 제공한다.세 개의 미니 슬롯을 사용할 경우 세 번의 미니슬롯이 피드백되어 도착했을 때 전송시간보다 빨리 충돌을 해결할 수 있다. 세 개의 미니 슬롯을 사용한 모델링과 시뮤레이션을 통해서 DQRAP 프로토콜은 처리율과 지연에 대하여 M/D/I 시스템에 거의 근접하는 것을 알 수 있다.DQRAP 브로토콜은 안정되고 전파지연에 민강하지 않으므로 현재 사용중인 위성 통신망, 근거리 통신망 (LAN)혹은 메트로폴리탄 통신망(MAN)등에 사용될 수 있다.

• 응용통계연구
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• 제28권2호
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• pp.211-219
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• 2015

일반화 선형혼합모델은 일반적으로 경시적 범주형 자료를 분석하는데 사용된다. 이 모델에서 임의효과는 반복 측정치들의 시간에 따른 의존성을 설명한다. 임의효과 공분산행렬의 추정은 여러가지 제약조건들 때문에 쉽지 않은 문제이다. 제약조건으로는 행렬의 모수들의 수가 많으며, 또한 추정된 공분산행렬은 양정치성을 만족하여야 한다. 이러한 제한을 극복하기 위해, 임의효과 공분산행렬의 모형화를 위한 여러가지 방법이 제안되었다: 수정 단냠레스키분해, 이동평균 단냠레스키분해와 부분 자기상관행렬을 이용한 방법이 있다. 이 논문에서 위의 제안된 방법들을 소개한다.

• 대한한의학회지
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• 제39권1호
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• pp.44-54
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• 2018

Objectives: The objective of this study is to investigate the effects of drinking alcohol on bio-electrical potential at twelve source points. Methods: Twenty healthy adults were assigned to alcohol and water groups by a random cross-over design. Bio-electrical potential at twelve source points were measured before and after drinking alcohol or water and the change of bio-electrical potential was analyzed and compared between the alcohol and the water groups. Results: Bio-electrical potential at LI4, ST42, KI3, PC7, TE4, GB40, LR3 in the alcohol group was significantly increased compared to those in the water group. Conclusions: Drinking alcohol increased bio-electrical potential at source points of LI, ST, KI, PC, TE, GB and LR in healthy human subjects.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1998년도 하계학술대회 논문집 G
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• pp.2360-2362
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• 1998

This paper presents a new collison-free trajectory problem for SCARA robot manipulator. we use artificial potential field for collison detection and avoidance. The potential function is typically defined as the sum of attractive potential pulling the robot toward the goal configuration and a repulsive potential pushing the robot away from the obstacles. In here, end-effector of manipulator is represented as a particle in configuration space and moving obstacles is simply represented, too. we consider not fixed obstacle but moving obstacle in random. So, we propose new distance function of artificial potential field with moving obstacle for SCARA robot. At every sampling time, the artificial potential field is update and the force driving manipulator is derived from the gradient vector of artificial potential field. To real-time path planning, we apply very simple modeling to obstacle. Some simulation results show the effectiveness of the proposed approach.

• 감성과학
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• 제20권2호
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• pp.149-160
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• 2017

가설검증 과정에서 자료 분석 결과 산출된 통계치에 대한 해석은 몇 가지 통계학적 이론을 토대로 분석 결과 산출된 관련 통계치의 이론적 확률 분포에 의해 좌우된다. 예를 들어 실험 조건 간 측정치의 평균 차이에 대한 통계적 유의미성은 대개 전집 특성에 대한 몇 가지 이론적 가정에 기초해 구성된 해당 평균 차이값의 확률 분포(예: Student's t)에 기초해 결정된다. 본 연구는 이러한 이론적 통계치의 분포가 아닌 실측정 자료의 무선 재구성을 통해 얻어진 경험적 통계치의 분포에 기초해 가설 검증을 시도하는 무선재추출법의 기본 논리와 장점을 살펴보고 사건관련전위 분석 상황에서의 응용 가능성을 모색하였다. 더 나아가 무선 추출 원리에 기초한 무선치환법이 적용된 구체적 사례를 소개하고 ERP 자료 분석에 있어서 경험적 통계 분석 적용에 앞서 유의할 점을 살펴봄으로써 뇌파 연구자들의 무선재추출법에 대한 정확한 이해를 도모하였다.

• Proceedings of the National Institute of Ecology of the Republic of Korea
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• 제1권1호
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• pp.74-82
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• 2020

Predictions of suitable habitat areas can provide important information pertaining to the risk assessment and management of alien plants at early stage of their establishment. Here, we predict the invasion potential of Muhlenbergia capillaris (pink muhly) in South Korea using five bioclimatic variables. We adopt four models (generalized linear model, generalized additive model, random forest (RF), and artificial neural network) for projection based on 630 presence and 600 pseudo-absence data points. The RF model yielded the highest performance. The presence probability of M. capillaris was highest within an annual temperature range of 12 to 24℃ and with precipitation from 800 to 1,300 mm. The occurrence of M. capillaris was positively associated with the precipitation of the driest quarter. The projection map showed that suitable areas for M. capillaris are mainly concentrated in the southern coastal regions of South Korea, where temperatures and precipitation are higher than in other regions, especially in the winter season. We can conclude that M. capillaris is not considered to be invasive based on a habitat suitability map. However, there is a possibility that rising temperatures and increasing precipitation levels in winter can accelerate the expansion of this plant on the Korean Peninsula.

• Earthquakes and Structures
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• 제13권1호
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• pp.79-87
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• 2017

Seismic analysis of local site conditions is fundamental for a reliable site seismic hazard assessment. It plays a major role in mitigation of seismic damage potential through the prediction of surface ground motion in terms of amplitude, frequency content and duration. Such analysis requires the determination of the transfer function, which is a simple tool for characterizing a soil profile by estimating its vibration frequencies and its amplification potential. In this study, numerical simulations are carried out and are then combined with a statistical study to allow the characterization of design sites classified by the Algerian Building Seismic Code (RPA99, ver 2003), by average transfer functions. The mean transfer functions are thereafter used to compute RPA99 average site factors. In this regard, coming up seismic fields are simulated based on Power Spectral Density Functions (PSDF) defined at the rock basement. Results are also used to compute average site factor where, actual and synthetic time histories are introduced. In absence of measurement data, it is found that the proposed approach can be used for a better soil characterization.

• 한국해양공학회지
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• 제37권6호
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• pp.238-246
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• 2023

This paper proposes an effective inertia coefficient (EIC) in the Morison equation for better wave-force calculations. The OC4 semi-submersible floating offshore wind turbine (FOWT) platform was considered to test the feasibility. Large diffraction at large Keulegan-Carpenter (KC) numbers and the interaction between columns can result in errors in estimating the wave force using the Morison equation with a theoretical inertia coefficient, which can be corrected by the EIC as a function of the wave period and direction. The horizontal and vertical wave forces were calculated using the Morison equation and potential theory at each column, wave period, and wave direction. The EICs of each column were then obtained, resulting in a minimal difference between the Morison inertia force and the wave excitation force by the potential theory. The EICs, wave forces, phase angles, and dynamic motions were compared to confirm the feasibility of an EIC concept under regular and random waves.

• 생명과학회지
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• 제16권1호
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• pp.88-94
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• 2006

본 연구에서 넙치와 조기의 원산지를 판별하기 위한 도구로 RAPD PCR 방법의 가능성을 확인하였다. 넙치는 한국의 주문진 자연산, 통영 양식산, 거제 양식산 그리고 북한 자연산을 실험에 사용하였다. 조기는 한국산과 중국산을 사용하였다. 넙치의 RAPD 패턴에서는 뚜렷하고 일관성이 있는 진단용 띠들을 쉽게 찾을 수 있었다. 조기의 경우에는 유전적인 이질성으로 인하여 각 개체의 RAPD 패턴에서는 일관성이 있는 진단용 띠를 찾기 어려웠지만 각 원산지별로 얻은 RAPD 패턴에서는 가능성이 있는 진단용 띠들을 찾을 수 있었다.