• 한국의학물리학회지:의학물리
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• 제29권1호
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• pp.23-28
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• 2018

The purpose of this study is to build a database of patient information for efficient radiotherapy management. Microsoft Office Access was used to build the database owing to its convenience and compatibility. The most important aspect when building the patient database is to make the input and management of patient information efficient at every step of radiotherapy process. The information input starts from the patient's first visit to the radiation therapy department and ends upon completion of the radiotherapy. The forms for each step of radiotherapy process include the patient information form, the radiotherapy schedule form, the radiotherapy information form, the simulation order form, and the patient history form. Every form is centrically connected to the radiation oncology department's patient information form. A test revealed that the database was found to be efficient in managing patient information at each step. An important benefit of this database is improved efficiency in radiotherapy management. Information on patients who received radiotherapy is stored in a database. This means that this clinical data can be found easily and used in future, which will be helpful in research studies on the radiation oncology department. Benefits such as these will potentially contribute to improved radiotherapy quality.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.126-128
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• 2002

A learning system was built into an on-line, multi-institutional radiotherapy database, where the treatment history records and the results in each institution were integrated, each radiotherapy planning was supported, and it led to the improvement in treatment results.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 1999년도 Japanese Journal of Medical Physics
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• pp.312-315
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• 1999

To improve quality and reliability of a multi-institutuonal radiation oncology database and to enhance the results of radiotherapy, we developed software which can generate another software automatically for converting an existed database to an integrated multi-institutional database ROGAD [Radiation Oncology Greater Area Database].

• 대한암한의학회지
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• 제20권2호
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• pp.51-59
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• 2015

Objective: This paper is to investigate the current evidence and clinical effectiveness of mountain ginseng pharmacopuncture (MGP) in cancer treatment. Methods: Along with hand searches, relevant literatures were searched from Korean medical database until November 2015 without language restriction and clinical researches were selected for this review. Results: Nine articles were searched. The MGP was generally prepared in the concentration of ten percent. Also, the MGP has been used by intravenous injection much more than acupoint injection. The clinical effects were the suppression of the cancer cell growth, the improvement the quality of life, the reduction of the side effect by chemotherapy and radiotherapy. Conclusion: This analysis suggests that the MGP can be used as a single therapy or a supportive therapy with conventional therapies, which are chemotherapy or radiotherapy.

• Radiation Oncology Journal
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• 제30권1호
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• pp.43-48
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• 2012

Purpose: To develop the dose volume histogram (DVH) management software which guides the evaluation of radiotherapy (RT) plan of a new case according to the biological consequences of the DVHs from the previously treated patients. Materials and Methods: We determined the radiation pneumonitis (RP) as an biological response parameter in order to develop DVH management software. We retrospectively reviewed the medical records of lung cancer patients treated with curative 3-dimensional conformal radiation therapy (3D-CRT). The biological event was defined as RP of the Radiation Therapy Oncology Group (RTOG) grade III or more. Results: The DVH management software consisted of three parts (pre-existing DVH database, graphical tool, and $Pinnacle^3$ script). The pre-existing DVH data were retrieved from 128 patients. RP events were tagged to the specific DVH data through retrospective review of patients' medical records. The graphical tool was developed to present the complication histogram derived from the preexisting database (DVH and RP) and was implemented into the radiation treatment planning (RTP) system, $Pinnacle^3$ v8.0 (Phillips Healthcare). The software was designed for the pre-existing database to be updated easily by tagging the specific DVH data with the new incidence of RP events at the time of patients' follow-up. Conclusion: We developed the DVH management software as an effective tool to incorporate the phenomenological consequences derived from the pre-existing database in the evaluation of a new RT plan. It can be used not only for lung cancer patients but also for the other disease site with different toxicity parameters.

• Asian Pacific Journal of Cancer Prevention
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• 제16권4호
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• pp.1435-1442
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• 2015

Purpose: To study the patient load, treatment pattern, survival outcome and its predictors in patients with brain metastases treated by radiotherapy. Materials and Methods: Data for patients with brain metastases treated by radiotherapy between 2003 and 2007 were collected from medical records, the hospital information system database, and a population-based tumor registry database until death or at least 5 years after treatment and retrospectively reviewed. Results: The number of treatments for brain metastases gradually increased from 48 in 2003 to 107 in 2007, with more than 70% from lung and breast cancers. The majority were treated with whole brain radiation of 30 Gy (3 Gy X 10 fractions) by cobalt-60 machine, using radiation alone. The overall median survival of the 418 patients was 3.9 months. Cohort analysis of relative survival after radiotherapy was as follows: 52% at 3 months, 18% at 1 year and 3% at 5 years in males; and 66% at 3 months, 26% at 1 year and 7% at 5 years in females. Multivariate analysis demonstrated that the patients treated with combined modalities had a better prognosis. Poor prognostic factors included primary cancer from the lung or gastrointestinal tract, emergency or urgent consultation, poor performance status (ECOG 3-4), and a hemoglobin level before treatment of less than 10 g/dl. Conclusions: This study identified an increasing trend of patient load with brain metastases. Possible over-treatment and under-treatment were demonstrated with a wide range of survival results. Practical prognostic scoring systems to assist in decision-making for optimal treatment of different patient groups is absolutely necessary; it is a key strategy for balancing good quality of care and patient load.

• Asian Pacific Journal of Cancer Prevention
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• 제14권12호
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• pp.7743-7748
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• 2013

Background: To study the pattern of patient load, personnel and equipment resources from 30-years experience in Southern Thailand. Materials and Methods: This retrospective study collected secondary data from the Division of Therapeutic Radiology and Oncology and the Songklanagarind Hospital Tumor Registry database, Faculty of Medicine, Prince of Songkla University, during the period of 1982-2012. Results: The number of new patients who had radiation treatment gradually increased from 121 in 1982 to 2,178 in 2011. Shortages of all kinds of personnel were demonstrated as compared to the recommendations, especially in radiotherapy technicians. In 2011, Southern Thailand, with two radiotherapy centers, had 0.44 megavoltage radiotherapy machines (cobalt or linear accelerator) per million of population. This number is suboptimal, but could be managed cost-effectively by prolonging machine operating times during personnel shortages. Conclusions: This study identified a discrepancy between workload and resources in one medical school radiotherapy center in Southern Thailand. This information is crucial for future strategic planning both regionally and nationally.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.177-179
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• 2002

We have developed a scheduling system for heavy ion radiotherapy considering the condition of three treatment rooms and treatment planning for each patient. This system consists of a database (patient information, treatment method and machine schedule), a schedule for radiotherapy and WEB server. All operation of this system, such as data input, to change and to view the schedule, are performed by using a WEB browser. In order to protect personal information for the patients, access privilege to each information are limited by according to the occupational category. This system is connected with a hospital central information management system (AMIDAS) and an irradiation-managing computer for the heavy ion radiotherapy. A basic information for the patient is got from AMIDAS and the daily schedule sends to the treatment control computer at each treatment room through the irradiation-managing computer every morning. The daily, weekly, monthly schedules in the treatment room and the treatment condition of each patient are shared on the WEB browser with the all participants of the heavy ion therapy. This system could be useful to save a time to generate a treatment schedule and to inform us the most up-to-date treatment schedule and the related information at the same time.

• Radiation Oncology Journal
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• 제8권1호
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• pp.103-109
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• 1990

우리나라 실정에 적합한 방사선 치료 환자들의 자료처리와 그 응용을 위한 전산화 시스템 이 본과에서 1987년 개발된 이래 현재까지 매우 유용하게 운영되고 있다. 방사선 치료계획용 Eclipsc 전산기를 주처리기기로 한 본 시스템은 Fortran-5로 프로그람되어 있고 AOS로 프로그람이 처리되고 있다. 방사선 치료를 받은 환자 30,000명에 관한 자료를 수록할 수 있는 용량으로 개발되었다. 본 시스템은 동일 환자가 재발 또는 전이 등의 이유로 재차 치료를 받는 경우가 있을지라도 5회까지는 각각 독립적인 자료로 입출력 가능하지만 그 자료들은 서로 연계적으로 수록되는 구조로 되어 있다. 동일한 방식으로 방사선 치료후 60회까지의 정기검진 자료가 수록 및 입출력 가능하다. 본 시스템의 응용 소프트웨어는 사용이 매 간편하며 이를 이용하여 특정 환자에 대하여 수록된 자료 전체를 검색하거나 특정 조건에 맞는 환자들의 자료중 필요한 부분만 선택하여 검색할 수 있고, 특정 기간중에 치료받은 환자들을 대상으로 하여 분석하고자 하는 인자들에 관한 통계적 분석이 가능하며, 수록된 자료중 특정 조건에 맞는 환자들의 생명표적 생존율 또는 합병율 산출이 가능하다. 상기의 생명표적 분석은 미수록된 자료인 경우에도 자판을 통한 입력으로도 가능하다. 본 시스템의 구조, 운용 및 자료 처리에 의한 응용예 등을 보고한다.

• Asian Pacific Journal of Cancer Prevention
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• 제17권8호
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• pp.3945-3951
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• 2016

Background: Whether concurrent chemotherapy treatment is superior to radiotherapy alone as an adjuvant regimen for postoperative cervical carcinoma with risk factors remains controversial. Materials and Methods: A literature search strategy examined Pubmed, Embase, the Cochrane Library, the China National Knowledge Internet Web, the Chinese Biomedical Database and the Wanfang Database. Article reference lists and scientific meeting abstracts were also screened. Controlled trials comparing concurrent chemoradiotherapy versus radiotherapy alone in postoperative cervical cancer were included. The methodological quality of non-randomized controlled trials was evaluated using the Newcastle-Ottawa Scale. Randomized controlled studies were evaluated with the Cochrane handbook. A meta-analysis was performed with RevMan 5.3. Results: A total of 1,073 patients from 11 clinical trials were analysed, with 582 patients in the concurrent chemoradiotherapy group and 491 patients in the radiotherapy group. Hazard ratios (HR) of 0.47 (95% CI 0.31-0.72) and 0.50 (95% CI 0.35-0.72) were observed for overall survival and progression-free survival, indicating a benefit from the additional use of concurrent chemotherapy. Subgroup analyses demonstrated that cervical cancer with high risk factors significantly benefitted from concurrent chemotherapy when examining overall survival (HR 0.44, 95% CI 0.28-0.67) and progression-free survival (HR 0.48, 95% CI 0.33-0.70), but patients with intermediate risk factors showed no benefit from concurrent chemotherapy in overall survival (HR 1.72, 95% CI 0.28-10.41) and progression-free survival (HR 1.09, 95% CI 0.19-6.14). No significant differences were observed for grade 3-4 anaemia (risk ratio (RR) 3.87, 95% CI 0.69-21.84), grade 3-4 thrombocytopenia (RR 3.04, 95% CI 0.88-10.58), grade 3-4 vomiting or nausea (RR 1.71, 95% CI 0.27-10.96), or grade 3-4 diarrhoea (RR 1.40, 95% CI 0.69-2.83). Significant differences were observed for grade 3-4 neutropenia in favour of the radiotherapy group (RR 7.23, 95% CI 3.94-13.26). Conclusions: In conclusion, concurrent chemoradiotherapy improves survival in postoperative cervical cancer with high risk factors but not in those with intermediate risk factors.