• Title/Summary/Keyword: radiation exposure dose

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DIFFERENTIAL EXPRESSION OF RADIATION RESPONSE GENES IN SPLEEN, LUNG, AND LIVER OF RATS FOLLOWING ACUTE OR CHRONIC RADIATION EXPOSURE

  • Jin, Hee;Jin, Yeung Bae;Lee, Ju-Woon;Kim, Jae-Kyung;Lee, Yun-Sil
    • Journal of Radiation Protection and Research
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    • v.40 no.1
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    • pp.25-35
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    • 2015
  • We analyzed the differential effects of histopathology, apoptosis and expression of radiation response genes after chronic low dose rate (LDR) and acute high dose rate (HDR) radiation exposure in spleen, lung and liver of rats. Female 6-week-old Sprague-Dawley rats were used. For chronic low-dose whole body irradiation, rats were maintained for 14 days in a $^{60}Co$ gamma ray irradiated room and received a cumulative dose of 2 Gy or 5 Gy. Rats in the acute whole body exposure group were exposed to an equal dose of radiation delivered as a single pulse ($^{137}Cs$-gamma). At 24 hours after exposure, spleen, lung and liver tissues were extracted for histopathologic examination, western blotting and RT-PCR analysis. 1. The spleen showed the most dramatic differential response to acute and chronic exposure, with the induction of substantial tissue damage by HDR but not by LDR radiation. Effects of LDR radiation on the lung were only apparent at the higher dose (5 Gy), but not at lower dose (2 Gy). In the liver, HDR and LDR exposure induced a similar damage response at both doses. RT-PCR analysis identified cyclin G1 as a LDR-responsive gene in the spleen of rats exposed to 2 Gy and 5 Gy gamma radiation and in the lung of animals irradiated with 5 Gy. 2. The effects of LDR radiation differed among lung, liver, and spleen tissues. The spleen showed the greatest differential effect between HDR and LDR. The response to LDR radiation may involve expression of cyclin G1.

Analysis of Cosmic Radiation Dose of People by Abroad Travel (일반인들의 항공여객기 이용 시 우주방사선 피폭선량 비교 분석)

  • Jang, Donggun;Shin, Sanghwa
    • Journal of radiological science and technology
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    • v.41 no.4
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    • pp.339-344
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    • 2018
  • Humans received an exposure dose of 2.4 mSv of natural radiation per year, of which the contribution of spacecraft accounts for about 75%. The crew of the aircraft has increased radiation exposure doses based on cosmic radiation safety management regulations There is no reference to air passengers. Therefore, in this study, we measured the radiation exposure dose received in the sky at high altitude during flight, and tried to compare the radiation exposure dose received by ordinary people during flight. We selected 20 sample specimens, including major tourist spots and the capital by continent with direct flights from Incheon International Airport. Using the CARI-6/6M model and the NAIRAS model, which are cosmic radiation prediction models provided at the National Radio Research Institute, we measured the cosmic radiation exposure dose by the selected flight and departure/arrival place. In the case of exposure dose, Beijing was the lowest at $2.87{\mu}Sv$ (NAIRAS) and $2.05{\mu}Sv$ (CARI - 6/6M), New York had the highest at $146.45{\mu}Sv$ (NAIRAS) and $79.42{\mu}Sv$ (CARI - 6/6M). We found that the route using Arctic routes at the same time and distance will receive more exposure dose than other paths. While the dose of cosmic radiation to be received during flight does not have a decisive influence on the human body, because of the greater risk of stochastic effects in the case of frequent flights and in children with high radiation sensitivity Institutional regulation should be prepared for this.

Study on Radiation Dose in the Medical Image Data Display Method - Focused on the DICOM Standard (의료영상 데이터에서의 피폭선량 표시 방법에 관한 고찰: DICOM 표준을 중심으로)

  • Kim, Jung-Su
    • Journal of radiological science and technology
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    • v.38 no.4
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    • pp.483-489
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    • 2015
  • DICOM (Digital Imaging and Communications in Medicine) standards are generally introduced as de facto and de jure standards in modern medical imaging devices to store and to transmit medical image information. DICOM Dose Structured Report (DICOM dose SR) is implemented to report radiation exposure information in image acquiring process. and DIOCM Modality Performed Procedure Step (DICOM MPPS) is also partly used to report this exposure with the information in its DICOM tag. This article is focused on three type of radiation exposure information of DICOM standards, 1) DICOM dose SR, 2) DICOM MPPS and 3) Radiation Exposure Monitoring(REM) profile by Integrating the Healthcare Enterprise(IHE), to study on radiation exposure reporting. Healthcare facility and its staff of medical imaging related to radiation exposure should have a deep understanding of radiation exposure, and it required a standards to enhance the quality control of medical imaging and the safety of patients and staffs. Staff member have to pay attention on radiation exposures and controling processes from the purchasing stage of X-ray devices.

Evaluation Internal Radiation Dose of Pediatric Patients during Medicine Tests Using Monte Carlo Simulation (몬테칼로 시뮬레이션을 이용한 소아 핵의학검사 시 인체내부 장기선량 평가)

  • Lee, Dong-yeon;Kang, Yeong-rok
    • Journal of radiological science and technology
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    • v.44 no.2
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    • pp.109-115
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    • 2021
  • In this study, a physical evaluation of internal radiation exposure in children was conducted using nuclear medicine test(Renal DTPA Dynamic Study) to simulate the distribution and effects of the radiation throughout the tracer kinetics over time. Monte Carlo simulations were performed to determine the internal medical radiation exposure during the tests and to provide basic data for medical radiation exposure management. Specifically, dose variability based on changes in the tracer kinetic was simulated over time. The internal exposure to the target organ (kidney) and other surrounding organs was then quantitatively evaluated and presented. When kidney function was normal, the dose to the target organ(kidney) was approximately 0.433 mGy/mCi, and the dose to the surrounding organs was approximately 0.138-0.266 mGy/mCi. When kidney function was abnormal, the dose to the surrounding organs was 0.228-0.419 mGy/mCi. This study achieved detailed radiation dose measurements in highly sensitive pediatric patients and enabled the prediction of radiation doses according to kidney function values. The proposed method can provide useful insights for medical radiation exposure management, which is particularly important and necessary for pediatric patients.

Occupational Radiation Exposure of Emergency Medical Technicians in Emergency Medical Centers in Korea (우리나라 응급의료센터 응급구조사의 직업적 방사선 노출)

  • Lee, Hyeongyeong;Park, Jeongim
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.27 no.3
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    • pp.170-179
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    • 2017
  • Objectives: This study aims to investigate the occupational radiation exposures of emergency medical technicians(EMTs) in emergency medical centers in Korea. The results will provide a basis for developing prevention programs to minimize adverse health effects relating to radiation exposure among emergency medical technicians working in this area. Methods: Radiation exposure doses were measured for twenty-two EMTs working in six emergency medical centers. Thermo Luminescent Dosimeters(TLD) were placed on three representative body parts, including chest, neck, and a finger. Measurements were conducted over the entire working hours of the participants for foor weeks. Dosimeters were analyzed according to a standard method by a KFDA-designated lab. Detection rate, annual radiation exposure dose, and relative levels to dose limit were derived based on the measured doses from the dosimeters. SPSS/Win 18.0 software(IBM, US) was used for statistical analysis. Results: Detection rates were 45.5%, 36.4%, and 45.5% for the dosimeters sampled from chest, neck, and a finger, respectively. The average annual doses were $2.39{\pm}3.44mSv/year$(range 0.38-10.0 mSv/year) for the chest, $2.72{\pm}3.05mSv/year$(2.00-11.34) for the neck, and $20.98{\pm}17.57mSv/year$(1.25-53.50) for the hand dose. The average annual eye dose was estimated to $3.61{\pm}2.37mSv/year$(1.50-8.34). The exposure dose levels of EMTs were comparable to those of radiologists, who showed relatively higher radiation dose among health care workers, as reported in another study. Conclusions: EMTs working in emergency medical centers are considered to be at risk of radiation exposure. Although the radiation exposure dose of EMTs does not exceed the dose limit, it is not negligible comparing to other professionals in health care sectors.

Doses of Pediatric and X-ray Examination Assistants according to Changes in Pediatric X-ray Exposure Conditions (소아 X선 촬영조건 변화에 따른 소아 및 촬영보조자 선량)

  • Beom-Jin Jang;Ha-Yun Nam;Hye-Min Shin;Dong-Min Yun;Seung-Kook Lee;In-Hwa Jang;Sungchul Kim
    • Journal of radiological science and technology
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    • v.46 no.5
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    • pp.409-415
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    • 2023
  • Although pediatric X-ray examinations are continuously increasing, there are not many studies on the radiation exposure to children and X-ray examination assistants according to X-ray Exposure conditions. Accordingly, we measured the radiation exposure dose of pediatric and X-ray examination assistants according to the standard guidelines and clinical average X-ray Exposure conditions when X-ray examination 10-year-old children. The effective dose and organ dose to pediatric were measured using an Dose area production meter and Monte Carlo-based PCXMC program, and the exposure dose of X-ray examination assistants was measured using an ion-chamber. When performing abdominal supine AP projection, the effective dose to children was up to 2.38 times higher under clinical average X-ray Exposure conditions than the standard guidelines. In addition, during abdominal supine AP projection, the radiation exposure dose to the X-ray examination assistants was highest on the hands at 0.0148 ~ 0.0709 mSv, and exposure dose could be reduced by up to 35% when wearing protective gloves. In conclusion, because the X-ray Exposure conditions used in clinical are unnecessarily high, unnecessary medical radiation exposure could be reduced if appropriate X-ray Exposure conditions and the radiation field area were minimized and the assistant wore shielding gloves.

A Study on Exposure Dose from Injection Work and Elution Work for Radiation Workers and Frequent Workers in Nuclear Medicine (핵의학과 주사와 분배업무 작업종사자 및 수시출입자 피폭선량연구)

  • Ju, Yong-Jin;Dong, Kyung-Rae;Choi, Eun-Jin;Kwak, Jong-Gil;Ryu, Jae-Kwang;Chung, Woon-Kwan
    • Journal of Radiation Industry
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    • v.11 no.1
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    • pp.47-54
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    • 2017
  • Compared to other occupations, there is a greater risk of exposure to radiation due to the use of radioisotopes in nuclear medicine for diagnostic evaluations and therapy. To consider ways to reduce exposure dose for those in nuclear medicine involved in injection work and elution work among radiation workers as well as for sanitation workers and trainees among frequent workers an investigation into exposure dose and situational analysis from changes in yearly exposure dose evaluations, changes in work environment and changes in forms of inspection were conducted. Exposure dose measurements were taken by using EPD MK2 worn during working hours for one injection worker, one elution worker, two sanitation workers, and one trainee at a general hospital in the Seoul area for three days from July 18th to 20th 2016. Radiation from radioisotopes which are a part of nuclear medicine can significantly affect not only radiation workers who deal with radioisotopes directly but also frequency works as well. According to this study the annual dose limit for elution workers and injection workers were considered safe as the amount of exposure was not large enough to have a significant effect. The limits of this study consist in the duration of this study and the quantity of participants. Also there was a limitation of the measurement device involving accumulated exposure, where the EPD MK2 cannot check the changes in exposure according to a particular activity.

Methodology for Calculating Correction Factors to Improve the Accuracy of Radiation Dose Predictions for High-Exposure Tasks in Nuclear Power Plants Using Computational Scenarios (원전 고피폭 작업의 예측 피폭선량 정확도 개선을 위한 전산코드 시나리오 보정인자 도출 방법론)

  • Changju Song;Tae Young Kong;Jiung Kim;Jaeok Park;Seungho Jo;Hee Geun Kim;Yongkwon Kim
    • Journal of Radiation Industry
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    • v.18 no.3
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    • pp.223-226
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    • 2024
  • It is essential to precisely evaluate the expected dose (collective dose) before performing high-exposure tasks in nuclear power plants because those have a high potential to cause significant radiation exposure to workers. A dose evaluation method is to design the scenarios of high-exposure tasks using computational codes, which allows for the calculation of the expected collective dose. Although these computational scenarios are useful for estimating the expected radiation dose and establishing radiation protection plans, the calculated doses may not perfectly match the actual doses that workers receive during tasks due to differences between the scenario and the actual circumstances in the radiation fields. Therefore, this study presents a methodology for calculating correction factors to improve the accuracy of dose predictions from computational scenarios. This approach aims to make the predicted collective dose before the task closer to the actual dose received by workers, thereby enhancing radiation safety for personnel performing high-exposure tasks. Additionally, these correction factors will help accurately predict doses under various working conditions in the future, contributing to minimizing radiation exposure risks for nuclear power plant workers.

Analysis of Cosmic Radiation Exposure for Domestic Flight Crews in Korea

  • Ahn, Hee-Bok;Hwang, Junga;Kwak, Jaeyoung;Kim, Kyuwang
    • Journal of Astronomy and Space Sciences
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    • v.39 no.2
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    • pp.51-57
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    • 2022
  • Cosmic radiation exposure of the flight crews in Korea has been managed by Radiation Safety Management around Living Life Act under Nuclear Safety and Security Commission. However, the domestic flight crews are excluded from the Act because of relatively low route dose exposure compared to that of international flight crews. But we found that the accumulated total annual dose of domestic flight crews is far from negligible because of relatively long total flight time and too many flights. In this study, to suggest the necessity of management of domestic flight crews' radiation exposure, we statistically analyzed domestic flight crew's accumulative annual dose by using cosmic radiation estimation models of the Civil Aviation Research Institute (CARI)-6M, Nowcast of Atmospheric Ionizing Radiation for Aviation Safety (NAIRAS), and Korean Radiation Exposure Assessment Model (KREAM) and compared with in-situ measurements of Liulin-6K LET spectrometer. As a result, the average exposure dose of domestic flight crews was found to be 0.5-0.8 mSv. We also expect that our result might provide the basis to include the domestic flight crews as radiation workers, not just international flight attendants.

A Comparative Analysis of Exposure Doses between the Radiation Workers in Dental and General Hospital (일반병원과 치과병원과의 방사선 관계종사자 피폭선량 비교분석)

  • Yang, Nam-Hee;Chung, Woon-Kwan;Dong, Kyung-Rae;Choi, Eun-Jin;Ju, Yong-Jin;Song, Ha-jin
    • Journal of Radiation Industry
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    • v.9 no.1
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    • pp.47-55
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    • 2015
  • Research and investigation is required for the exposure dose of radiation workers to work in the dental hospital as increasing interest in exposure dose of the dental hospital recently accordingly, study aim to minimize radiation exposure by making a follow-up study of individual exposure doses of radiation workers, analyzing the status on individual radiation exposure management, prediction the radiation disability risk levels by radiation, and alerting the workers to the danger of radiation exposure. Especially given the changes in the dental hospital radiation safety awareness conducted the study in order to minimize radiation exposure. This study performed analyses by a comparison between general and dental hospital, comparing each occupation, with the 116,220 exposure dose data by quarter and year of 5,811 subjects at general and dental hospital across South Korea from January 1, 2008 through December 31, 2012. The following are the results obtained by analyzing average values year and quarter. In term of hospital, average doses were significantly higer in general hospitals than detal ones. In terms of job, average doses were higher in radiological technologists the other workes. Especially, they showed statistically significant differences between radiological technologists than dentists. The above-mentioned results indicate that radiation workers were exposed to radiation for the past 5 years to the extent not exceeding the dose limit (maximum $50mSv\;y^{-1}$). The limitation of this study is that radiation workers before 2008 were excluded from the study. Objective evaluation standards did not apply to the work circumstance or condition of each hospital. Therefore, it is deemed necessary to work out analysis criteria that will be used as objective evaluation standard. It will be necessary to study radiation exposure in more precise ways on the basis of objective analysis standard in the furture. Should try to minimize the radiation individual dose of radiation workers.