• Title/Summary/Keyword: radiation effects

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The Effects of Far-Infrared on Rheumatoid Arthritis Induced Rats (원적외선 전신조사가 류마티스 관절염 유발 흰쥐에 미치는 영향)

  • Kim Gye Yeop;Cho Kyoung Oh;Kim Myung Hee;Cheong Hyun Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.18 no.5
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    • pp.1301-1308
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    • 2004
  • The purpose of this study was to observe the effects of far-infrared on rheumatoid arthritis induced rats by type ⅡI collagen with the change of arthritis index, hind paw volume, TNF-α and histopathologic findings. Thirty-six Sprauge-Dawley rats which were divided into four group. Group Ⅰ : Normal group, Group Ⅱ : Collagen-Induced Arthritis group, Group Ⅲ : Far-Infrared 25㎝ radiation group, Group Ⅳ : Far-Infrared 35㎝ radiation group. The results of this study were as follows: In arthritis index, far-infrared radiation group(Ⅲ, Ⅳ) are more decreased than collagen-induced arthritis group(Ⅱ). Group Ⅲ and Ⅳ showed the most significant effect at 14 day(p<0.05). In hind paw, far-infrared 25㎝ radiation group(Ⅲ) significantly decreased more than only collagen-induced arthritis group on day 14(p<0.05). Far-infrared 35㎝ radiation group(Ⅳ) significantly decreased more than collagen-induced arthritis group on day 3, 7 and 14(p<0.05). In the ELISA study of TNF-α concentration, collagen-induced arthritis group significantly increased in the concentration more than normal group. Far-infrared radiation group(Ⅲ, Ⅳ) decreased in TNF-α concentration more than collagen-induced arthritis group(Ⅱ) on day 14. In histopathologic findings, collagen-induced arthritis(Ⅱ) and far-infrared 25㎝ radiation group(Ⅲ) increased in synovial membrane thickness on 3 day. Far-infrared 35 em radiation group(Ⅳ) decreased in the concentration more than collagen-induced arthritis group on day 14. The above results suggest that far-infrared radiation effectively reduced in rheumatoid arthritis. It would be considered that far-infrared has an effects on relieving rheumatoid arthritis.

A MODEL FOR PROTECTIVE BEHAVIOR AGAINST THE HARMFUL EFFECTS OF RADIATION FOR RADIOLOGICAL TECHNOLOGISTS IN MEDICAL CENTERS

  • Han, Eun-Ok;Moon, In-Ok
    • Journal of Radiation Protection and Research
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    • v.34 no.3
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    • pp.95-101
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    • 2009
  • Protective behavior of radiological technologists against radiation exposure is important to achieve reduction of the patient doses without compromising medical achievements. This study attempts to provide a basic model for the sophisticated intervention strategy that increases the level of the protective behavior of the technologists. The model was applied to real situations in Korea to demonstrate its utility. The results of this study are summarized as follows: First, the protective environment showed the highest relationship in the factors considered, r=0.637 (p<0.01). Secondly, the important factors were protective environment in environment characteristics, expectation for the protective behavior 0.228 (p<0.001), self-efficacy 0.142 (p<0.001), and attitude for the protective behavior 0.178 (p<0.001) in personal characteristics, and daily patient -0.112 (p<0.001) and number of the participation in the education session for the protective behavior 0.074 (p<0.05). Thirdly, the final protective behavior model by a path analysis method had direct influence on the attitude 0.171 (p<0.01) and environment 0.405 (p<0.01) for the protective behavior, self efficacy 0.122 (p<0.01), expectation for the protective behavior 0.16 (p<0.01), and self-efficacy in the specialty of projects 0.154 (p<0.01). The acceptance of the model determined by the absolute fit index (GFI), 0.969, and by the incremental fit index (CFI), 0.943, showed very significant levels. Value of $x^2$/df that is a factor applied to verify the acceptance of the model was 37, which implies that the result can be accepted in the desirable range. In addition, the parsimonious fit index configured by AGFI (0.890) and TLI (0.852) was also considered as a scale that accepts the model in practical applications. In case of the establishment of some specific intervention strategies based on the protective behavior model against harmful radiation effects proposed in this study, the strategy will provide an effective way to prevent medical harmful radiation effects that could cause severe injuries to people.

Photoimmunological and Photobiological Action of Infrared Radiation

  • Danno, Kiichiro
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.194-196
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    • 2002
  • While ultraviolet radiation alters various cutaneous cell functions, little is known about photo-immunological and photobiological effects of infrared radiation (IR) on the skin except its local thermal effects. The fIrst part of this study demonstrated that single exposure of mouse skin to near IR (0.7 - 1.3 $\mu$m) reversibly suppressed the proliferating activity of the epidermis, the density of Langerhans cells, and the ability of skin to induce contact hypersensitivity reaction. The second part demonstrated that the rate of wound closure was significantly accelerated by repeated exposures in animal models. The production of transforming growth factor-$\beta$l and matrix metalloproteinase-2, which are responsible for the wound healing processes, was significantly upregulated by irradiation, as shown by enzyme immunoassay, zymography, and reverse transcription polymerase chain reaction. Thermal controls were negative. The results suggest that near-IR irradiation can modulate the epidermal proliferation and part of the skin immune system, and stimulate the wound healing processes, presumably by non-thermal effects.

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Analysis of the effects of human head and hand on the radiation chracteristics of hand-held transceiver (인체의 머리와 손이 개인휴대 단말기의 복사특성에 미치는 영향 해석)

  • 윤종철;최재훈
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.35D no.7
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    • pp.1-8
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    • 1998
  • In this paper, the radiation characteristics of a bar-type tranceiver are analyzed by using FDTD method and the effectiveness of the analysis method is verified by comparing the calculated data with experimental data. The effects of human head and hand on the radiation characteristics of fold-type transceiver are analyzed. In order to observe the effects of human head and hand on the input impedance and far-field radiation pattern, a fold-type transceiver with .lambda./4 monopole antenna wrapped by human hand operating in the proximity of hea dis modeled an analyzed.

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Effects of Different Calm Conditions on the Radiation Exposure Due to the Operation of a Nuclear Facility at KAERI Site

  • Hwang, Won-Tae;Han, Moon-Hee;Kim, Eun-Han;Suh, Kyung-Suk;Gyuseong Cho
    • Proceedings of the Korean Nuclear Society Conference
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    • 1996.05d
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    • pp.28-33
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    • 1996
  • Wind-speed has much effect on the dispersion of the radioactive effluents released into the atmosphere. Accurate measurement of low wind-speeds is very important for the realistic assessment of radiation exposure. The objective of this study is to analyze the effects of different calm conditions on the radiation exposure due to the normal operation of a nuclear facility at KAERI (Korea Atomic Energy Research Institute) site. When calm condition is changed from 0.5 m/sec to 0.21 m/sec, the effects on radiation exposure show a distinct difference.

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Radiosensitization Effects of a Zataria multiflora Extract on Human Glioblastoma Cells

  • Aghamohammadi, Azar;Hosseinimehr, Seyed Jalal;Ghasemi, Arash;Azadbakht, Mohammad;Pourfallah, Tayyeb Allahverdi
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.16
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    • pp.7285-7290
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    • 2015
  • Background: Although radiotherapy is one of the most effective strategies in the treatment of cancers, it is associated with short and long term side effects on normal tissues. Zataria multiflora Boiss (Laminacea) (ZM) has several biological properties such as antioxidant and anti-inflammation activities.Here we investigated cell killing effects of a hydroalcoholic Zataria multiflora extract on cell death induced by ionizing radiation in a human glioblastoma cell line (A172) and human non-malignant fibroblasts (HFFF2) in vitro. Materials and Methods: A172 and HFFF2 cells were treated with a hydroalcoholic extract of dried aerial parts of Zataria multiflora at different concentrations (25, 50, 100, 150 and $200{\mu}g/ml$) and then exposed to ionizing radiation (IR). Cell proliferation and DNA fragmentation were evaluated. Thymol content in the extract was analyzed and quantified by HPLC methods. Results: A172 cell proliferation was significantly inhibited by ZM. The percentage cell survival was $91.8{\pm}8.57$ for cells treated with $200{\mu}g/ml$ of ZM extract alone while it was $76.0{\pm}4.27$ and $66.2{\pm}8.42$ for cells treated with ZM and exposed to IR at doses of 3Gy and 6Gy, respectively. Radiation-induced apoptosis in A172 cells was significantly increased following treatment with ZM at doses of $200{\mu}g/ml$. ZM extract did not exhibit any enhanced cell killing effects and apoptosis caused by IR on HFFF2 cells. Conclusions: These data show selective radiosensitization effects of ZM in A172 cells apparently due to increased radiation-induced apoptosis.

N-Acetylphytosphingosine Enhances the Radiosensitivity of Lung Cancer Cell Line NCI-H460

  • Han, Youngsoo;Kim, Kisung;Shim, Ji-Young;Park, Changsoe;Song, Jie-Young;Yun, Yeon-Sook
    • Molecules and Cells
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    • v.25 no.2
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    • pp.224-230
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    • 2008
  • Ceramides are well-known second messengers that induce apoptosis in various kinds of cancer cells, and their effects are closely related to radiation sensitivity. Phytoceramides, the yeast counterparts of the mammalian ceramides, are also reported to induce apoptosis. We investigated the effect of a novel ceramide derivative, N-acetylphytosphingosine (NAPS), on the radiosensitivity of NCI-H460 human lung carcinoma cells and its differential cytotoxicity in tumor and normal cells. The combination of NAPS with radiation significantly increased clonogenic cell death and caspase-dependent apoptosis. The combined treatment greatly increased Bax expression and Bid cleavage, but not Bcl-2 expression. However, there was no effect on radiosensitivity and apoptosis in BEAS2B cells, which derive from normal human bronchial epithelium. Cell proliferation and DNA synthesis were significantly inhibited by NAPS in both NCI-H460 and BEAS2B cells, but only the BEAS2B cells recovered by 48h after removal of the NAPS. Furthermore, the NCI-H460 cells underwent more DNA fragmentation than the BEAS2B cells in response to NAPS. Our results indicate that NAPS may be a potential radiosensitizing agent with differential effects on tumor vs. normal cells.

A Prediction of Radiation Power for the Planar Array Acoustic Transducer Considering Mutual Coupling Effects (상호 간섭 영향을 고려한 평면 배열형 음향 트랜스듀서의 방사 출력 예측)

  • Lee, Jong-Kil;Seo, In-Chang
    • The Journal of the Acoustical Society of Korea
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    • v.15 no.1
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    • pp.17-22
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    • 1996
  • Planar array of acoustic transducer is normally used in a sonar system. Acoustic radiation makes beam pattern in underwater uses. The main source of the beam pattern is due to the transducer array. Therefore, estimation of the acoustic radiated power is necessary to predict the performance and efficiency of the transducer. As an example of the acoustic radiation power, nine acoustic transducers mounted to a rigid infinite baffle are considered in a theoretical model. Each piston's acoustic radiation consists of self- and mutual-radiation impedances. Total radiation impedances and acoustic radiation power of the transducers are extracted using on the theory of an equivalent electric circuit. The theoretical results reveal that acoustic radiation power of the transducer depends on the mutual coupling effects.

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Heat Transfer Analysis of the Radiation Shield in Cryogenic Systems (극저온 시스템의 복사쉴드의 열전달 해석)

  • 정은수;장호명;박희찬;양형석
    • Progress in Superconductivity and Cryogenics
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    • v.4 no.1
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    • pp.124-128
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    • 2002
  • A numerical model to obtain the temperature distribution in a radiation shield of cryogenic systems was proposed. Conformal mapping was used to transform the eccentric physical region of the upper plate to the concentric numerical region. The effects of the thickness of the radiation shield, the emissivities of the vacuum chamber and the radiation shield, and the eccentricity between the centers of the upper plate and the contact area with a cryocooler on the maximum temperature difference in a radiation shield were shown.