• Title/Summary/Keyword: quantity approach methods

Search Result 56, Processing Time 0.027 seconds

A Study on the Spatiotemporal Characteristics of a Hazard-based Index using the Pollutant Release and Transfer Register Data (화학물질 배출·이동량 자료를 이용한 유해기반 지수의 시공간 특성 연구)

  • Kim, Shijin;Lim, Yu-ra;Bae, Hyun-Joo
    • Journal of Environmental Health Sciences
    • /
    • v.47 no.2
    • /
    • pp.144-154
    • /
    • 2021
  • Objectives: This study was intended to identify hazard contribution by region, media, and chemical by calculating a hazard-based index using pollutant release and transfer register (PRTR) data. Methods: PRTR data for the period 2011 to 2016 was analyzed to examine the regional trends in toxic releases in terms of quantity and to create a corresponding hazard-based index. For the hazard-based index, the Risk-Screening Environmental Indicators (RSEI) Model was used. Results: The results of the trend analysis show that total releases decreased slightly, but health hazard levels increased consistently. According to the outcome of regional contribution analysis of the hazard-based index, Chungcheongnam-do, Jeollabuk-do and Gyeonggi-do Provinces showed a high ratio in the index for air and water release pollutants, while Gyeongsangbuk-do and Gyeongsangnam-do Provinces showed a high ratio in the index of soil release and waste transfer pollutants. Also, as a result of the analysis of the top ranked substances in the hazard-based index, it was found that chromium, cobalt and its compounds, and ethylene oxide contributed greatly to air release substances, while chromium, benzene, and lead and its compounds contributed greatly to water release substances. Conclusion: These results showed considerable disparities between total release and health hazard levels, especially in the analysis of contribution by regions and by chemical substance. Therefore, the hazard-based index should be used both to support a more comprehensive and robust approach to screening of chemicals for environmental health policy and for management.

Intracutaneous Delivery of Gelatins Reduces Fat Accumulation in Subcutaneous Adipose Tissue

  • An, Sung-Min;Kim, Min Jae;Seong, Keum-Yong;Jeong, Jea Sic;Kang, Hyeon-Gu;Kim, So Young;Kim, Da Som;Kang, Da Hee;Yang, Seung Yun;An, Beum-Soo
    • Toxicological Research
    • /
    • v.35 no.4
    • /
    • pp.395-402
    • /
    • 2019
  • Subcutaneous adipose tissue (SAT) accumulation is a constitutional disorder resulting from metabolic syndrome. Although surgical and non-surgical methods for reducing SAT exist, patients remain non-compliant because of potential adverse effects and cost. In this study, we developed a new minimally-invasive approach to achieve SAT reduction, using a microneedle (MN) patch prepared from gelatin, which is capable of regulating fat metabolism. Four gelatin types were used: three derived from fish (SA-FG, GT-FG 220, and GT-FG 250), and one from swine (SM-PG 280). We applied gelatin-based MN patches five times over 4 weeks to rats with high-fat diet (HD)-induced obesity, and determined the resulting amount of SAT. We also investigated the histological features and determined the expression levels of fat metabolism-associated genes in SAT using hematoxylin and eosin staining and western blotting, respectively. SAT decreased following treatment with all four gelatin MN patches. Smaller adipocytes were observed in the regions treated with SA-FG, GT-FG 250, and SM-PG 280 MNs, demonstrating a decline in fat accumulation. The expression levels of fat metabolism-associated genes in the MN-treated SAT revealed that GT-FG 220 regulates fatty acid synthase (FASN) protein levels. These findings suggest that gelatin MN patches aid in decreasing the quantity of unwanted SAT by altering lipid metabolism and fat deposition.

Analysis of Registration Information of Randomized Controlled Clinical Trials on Suicide Attempters Based on WHO-ICTRP (자살시도자에 대한 무작위대조군연구의 등록 현황 분석: WHO-ICTRP를 중심으로)

  • Min-Ryeong Park;Ji-Won Lee;In-Jun Hwang;Chan-Young Kwon
    • Journal of Oriental Neuropsychiatry
    • /
    • v.34 no.3
    • /
    • pp.213-234
    • /
    • 2023
  • Objectives: To investigate current status of randomized controlled clinical trial (RCT) registration for suicide attempters. Methods: The World Health Organization International Clinical Trials Registry Platform (WHO-ICTRP) was used to search for data using 'suicide' as a search term. All registration information of RCTs registered up to April 2023 were collected. Results: Among a total of 68 RCTs registered, the United States ranked the highest in terms of quantity in this field (n=30, 46.15%), whereas Asia had only six (8.82%). A total of 62 (91.18%) RCTs involved individual interventions, while nine (13.24%) RCTs involved group interventions. Among individual interventions, 11 (16.18%) and 54 (79.41%) RCTs were on pharmacotherapy and psychotherapy, respectively. Within psychotherapy, there were a total of 17 (25%) studies utilizing digital media, with cognitive behavioral therapy (CBT) via phone being the most common approach. Among non-digital media-based studies, CBT was used the most frequently (n=11, 16.18%), followed by attempted suicide short intervention program (n=6, 8.82%). There were no studies using interventions from East Asian traditional medicine, including Korean medicine (KM). The most frequently used main outcome was the Beck scale for suicidal ideation. Conclusions: Studies on suicide attempts in Asia, especially in South Korea, are very scarce. Despite vigorous psychotherapeutic research in this field, KM psychotherapy has not been used. Thus, KM clinical trial for suicide attempters might be planned in the future based on our findings.

Experimental Study on the Water Content Formula of Fresh Concrete by Microwave Oven Drying Test Method (고주파 가열건조 시험방법에 의한 굳지 않은 콘크리트의 단위수량 추정식에 관한 실험적 연구)

  • Park, Min-Yong;Han, Min-Cheol
    • Journal of the Korea Institute of Building Construction
    • /
    • v.23 no.2
    • /
    • pp.143-152
    • /
    • 2023
  • In this research, the microwave oven drying method was investigated as a potential accurate testing approach for determining the water content of fresh concrete. To do so, water content estimation formulas employed in three prominent oven drying test methods were selected, and the calculation principles for each equation, along with potential error factors arising during the actual testing process, were considered. Moreover, a concrete test was conducted to validate the possible error factors. Consequently, it was confirmed that estimation errors in the water content of fresh concrete can occur due to sample deviations arising during the wet screening process for creating mortar specimens or deviations in the coarse aggregate sampling quantity during the sample collection process.

Application of Enzymatic Activity and Arsenic Respiratory Gene Quantification to Evaluate the Ecological Functional State of Stabilized Soils Nearby Closed Mines (안정화 처리된 폐광산 토양의 생태기능상태 평가를 위한 효소활성도 및 비소호흡유전자의 적용)

  • Park, Jae Eun;Lee, Byung-Tae;Lee, Sang Woo;Kim, Soon-Oh;Son, Ahjeong
    • Journal of Korean Society of Environmental Engineers
    • /
    • v.39 no.5
    • /
    • pp.265-276
    • /
    • 2017
  • Heavy metals leaching from closed mines have been causing severe environmental problems in nearby soil ecosystems. Mine reclamation in Korea has been recently implemented based on the heavy metal immobilization (a.k.a., stabilization). Since the immobilization temporarily fixes the heavy metals to the soil matrix, the potential risk of heavy metal leaching still exists. Therefore the appropriate monitoring and the related policies are required to safeguard the soils, where all the cultivations occur. The current monitoring methods are based on either heavy metal concentration or simple toxicity test. Those methods, however, are fragmented and hence it is difficult to evaluate the site in an integrated manner. In this study, as the integrated approach, ecological functional state evaluation with a multivariate statistical tool was employed targeting physiochemical soil properties, heavy metal concentrations, microbial enzymatic activity, and arsenic respiratory reductase gene quantity. Total 60 soil samples obtained from three mines (Pungjeong, Jeomdong, Seosung) were analyzed. As a result, the stabilized layer soil and lower layer soil have shown the similar pattern in Pungjeong mine. In contrast, Jeomdong and Seosung mine have shown the similarity between the stabilized layer soil and the cover layer soil, indicating the possible contamination of the cover layer soil.

Prototyping a BIM-enabled Design Tool for the Auto-arrangement of Interior Design Panels - Based on the Pattern Extraction of Bitmap Image Pixels and its Representation - (BIM기반 설계를 지원하는 인테리어 패널 자동배치 도구 프로토타입 구현 - 비트맵 이미지 픽셀 패턴의 추출과 패널 표현을 중심으로 -)

  • Huang, JinHua;Kim, HaYan;Lee, Jin-Kook
    • Design Convergence Study
    • /
    • v.15 no.5
    • /
    • pp.71-83
    • /
    • 2016
  • Interior panels are usually used in finishing of interior walls for not only decorative effects but also information transfer. According to designer's design placing interior panels may need repetitive tasks and the emphasis of this paper is to support an automation of these tasks. Considering the utilization characteristics of interior panels, we propose three method to present patterns by using bitmap image pixels and interior panels' shape changes, based on the theoretical consideration. In addition, in order to approve the possibility of the proposed methods, we have implemented the BIM based interior panels auto layout tool which applied one of the three methods to present patterns by using bitmap image pixel values and panel identification attributes. This tool also supports auto generation of quantity and panel arrangement sequence information that will be used in future construction phase. We expect that this approach will also be used in other decorative objects which require repetition of the basic units, such as floor tiles.

APPLICATION OF FUZZY SET THEORY IN SAFEGUARDS

  • Fattah, A.;Nishiwaki, Y.
    • Proceedings of the Korean Institute of Intelligent Systems Conference
    • /
    • 1993.06a
    • /
    • pp.1051-1054
    • /
    • 1993
  • The International Atomic Energy Agency's Statute in Article III.A.5 allows it“to establish and administer safeguards designed to ensure that special fissionable and other materials, services, equipment, facilities and information made available by the Agency or at its request or under its supervision or control are not used in such a way as to further any military purpose; and to apply safeguards, at the request of the parties, to any bilateral or multilateral arrangement, or at the request of a State, to any of that State's activities in the field of atomic energy”. Safeguards are essentially a technical means of verifying the fulfilment of political obligations undertaken by States and given a legal force in international agreements relating to the peaceful uses of nuclear energy. The main political objectives are: to assure the international community that States are complying with their non-proliferation and other peaceful undertakings; and to deter (a) the diversion of afeguarded nuclear materials to the production of nuclear explosives or for military purposes and (b) the misuse of safeguarded facilities with the aim of producing unsafeguarded nuclear material. It is clear that no international safeguards system can physically prevent diversion. The IAEA safeguards system is basically a verification measure designed to provide assurance in those cases in which diversion has not occurred. Verification is accomplished by two basic means: material accountancy and containment and surveillance measures. Nuclear material accountancy is the fundamental IAEA safeguards mechanism, while containment and surveillance serve as important complementary measures. Material accountancy refers to a collection of measurements and other determinations which enable the State and the Agency to maintain a current picture of the location and movement of nuclear material into and out of material balance areas, i. e. areas where all material entering or leaving is measurab e. A containment measure is one that is designed by taking advantage of structural characteristics, such as containers, tanks or pipes, etc. To establish the physical integrity of an area or item by preventing the undetected movement of nuclear material or equipment. Such measures involve the application of tamper-indicating or surveillance devices. Surveillance refers to both human and instrumental observation aimed at indicating the movement of nuclear material. The verification process consists of three over-lapping elements: (a) Provision by the State of information such as - design information describing nuclear installations; - accounting reports listing nuclear material inventories, receipts and shipments; - documents amplifying and clarifying reports, as applicable; - notification of international transfers of nuclear material. (b) Collection by the IAEA of information through inspection activities such as - verification of design information - examination of records and repo ts - measurement of nuclear material - examination of containment and surveillance measures - follow-up activities in case of unusual findings. (c) Evaluation of the information provided by the State and of that collected by inspectors to determine the completeness, accuracy and validity of the information provided by the State and to resolve any anomalies and discrepancies. To design an effective verification system, one must identify possible ways and means by which nuclear material could be diverted from peaceful uses, including means to conceal such diversions. These theoretical ways and means, which have become known as diversion strategies, are used as one of the basic inputs for the development of safeguards procedures, equipment and instrumentation. For analysis of implementation strategy purposes, it is assumed that non-compliance cannot be excluded a priori and that consequently there is a low but non-zero probability that a diversion could be attempted in all safeguards ituations. An important element of diversion strategies is the identification of various possible diversion paths; the amount, type and location of nuclear material involved, the physical route and conversion of the material that may take place, rate of removal and concealment methods, as appropriate. With regard to the physical route and conversion of nuclear material the following main categories may be considered: - unreported removal of nuclear material from an installation or during transit - unreported introduction of nuclear material into an installation - unreported transfer of nuclear material from one material balance area to another - unreported production of nuclear material, e. g. enrichment of uranium or production of plutonium - undeclared uses of the material within the installation. With respect to the amount of nuclear material that might be diverted in a given time (the diversion rate), the continuum between the following two limiting cases is cons dered: - one significant quantity or more in a short time, often known as abrupt diversion; and - one significant quantity or more per year, for example, by accumulation of smaller amounts each time to add up to a significant quantity over a period of one year, often called protracted diversion. Concealment methods may include: - restriction of access of inspectors - falsification of records, reports and other material balance areas - replacement of nuclear material, e. g. use of dummy objects - falsification of measurements or of their evaluation - interference with IAEA installed equipment.As a result of diversion and its concealment or other actions, anomalies will occur. All reasonable diversion routes, scenarios/strategies and concealment methods have to be taken into account in designing safeguards implementation strategies so as to provide sufficient opportunities for the IAEA to observe such anomalies. The safeguards approach for each facility will make a different use of these procedures, equipment and instrumentation according to the various diversion strategies which could be applicable to that facility and according to the detection and inspection goals which are applied. Postulated pathways sets of scenarios comprise those elements of diversion strategies which might be carried out at a facility or across a State's fuel cycle with declared or undeclared activities. All such factors, however, contain a degree of fuzziness that need a human judgment to make the ultimate conclusion that all material is being used for peaceful purposes. Safeguards has been traditionally based on verification of declared material and facilities using material accountancy as a fundamental measure. The strength of material accountancy is based on the fact that it allows to detect any diversion independent of the diversion route taken. Material accountancy detects a diversion after it actually happened and thus is powerless to physically prevent it and can only deter by the risk of early detection any contemplation by State authorities to carry out a diversion. Recently the IAEA has been faced with new challenges. To deal with these, various measures are being reconsidered to strengthen the safeguards system such as enhanced assessment of the completeness of the State's initial declaration of nuclear material and installations under its jurisdiction enhanced monitoring and analysis of open information and analysis of open information that may indicate inconsistencies with the State's safeguards obligations. Precise information vital for such enhanced assessments and analyses is normally not available or, if available, difficult and expensive collection of information would be necessary. Above all, realistic appraisal of truth needs sound human judgment.

  • PDF

An Empirical Measurement Way of Efficiency Prediction for Korean Seaports : SBM and Wilcoxson Signed-Rank Test Approach (항만의 효율성을 예측하기 위한 실증적 측정방법 - SBM과 윌콕슨부호순위검정접근 -)

  • Park, No-Gyeong
    • Journal of Korea Port Economic Association
    • /
    • v.24 no.4
    • /
    • pp.313-327
    • /
    • 2008
  • The purpose of this paper is to show the empirical measurement way for predicting the seaport efficiency by using SBM with Wilcoxson signed-rank test under CRS(constant returns to scale) condition for 20 Korean ports during 1994-2003 for 2 inputs(birthing capacity, cargo handling capacity) and 3 outputs(Export and Import Quantity, Number of Ship Calls, Port Revenue). The main empirical results of this paper are as follows. First, forecasting data have well reflected the real data according to the Wilcoxon signed rank test, because p values have exceeded the 0.05 significance level. Second, SBM has shown the effectiveness for predicting the ports efficiency even though the predicting powers are different according to the levels of p values. The policy implication to the Korean seaports and planner is that Korean seaports should introduce the new methods like SBM method with Wilcoxon signed rank test for predicting the port performance and enhancing the efficiency.

  • PDF

Strategy and Development of Recycling Technology for End-of-Life Vehicles(ELVs) in Germany

  • Kim, Jae-Ceung
    • Resources Recycling
    • /
    • v.14 no.3
    • /
    • pp.16-36
    • /
    • 2005
  • The quantity of passenger cars in industrial countries has been significantly increased in recent years. According to prognoses, this tendency is likely to continue in the forthcoming future. As a direct consequence, an increase of End-of Life-Vehicles (ELV) will confront us with the problem of "ELV-Recycling". In order to cope with this situation, the European regulation for the treatment of End-of-Life-Vehicles (09/2000) has been transferred to national law in Germany (ELV-Regulation from 1 July 2002). The long term aim is to reduce residues from the ELV-treatment to less than 5 wt% from 30 wt% within the next 10 years (2015). For that reason, there is a need for innovative and more efficient recycling techniques tailored to future materials in automobiles. The design process at automotive industry is continuously changing due to the strong demand on optional equipment and new technical solutions for fuel saving. Light materials, such as aluminum and plastics, consequently become more important and cause a decrease of ferrous metals. Since plastic materials are often used as compounds, a separation into initial material types by means of mechanical recycling methods is not possible. For that reason, efficient recycling can only be realized by introducing recycling-friendly car designs. In the end an integrated approach of auto makers and recycling industry is of decisive significance for the fulfillment of future regulations.

Retrospective studies of dental implant placement at each intraoral site and situation (임플란트 식립 유형에 따른 후향적 연구)

  • Hong, Ji-Youn;Chae, Gyung-Joon;Jung, Ui-Won;Kim, Chang-Sung;Cho, Kyoo-Sung;Chae, Jung-Kiu;Kim, Chong-Kwan;Choi, Seong-Ho
    • Journal of Periodontal and Implant Science
    • /
    • v.37 no.4
    • /
    • pp.805-824
    • /
    • 2007
  • Purpose: Developments in micro/macrostructures of implants and surgical techniques brought out stable outcomes of implant dentistry. The aim of this study was to evaluate the distributions of implant patients, the types of implanted sites, and the success or survival rates of various implant systems and to analyze the implant placement done at each specificintraoral site and situation. Materials and Methods: The data of dental implantations collected between 1992 and 2006 at the Department of Periodontology in 00000 University Hospital were analyzed. Results: 1. Largest part of the patients were at the age of 40s and 50s in bothgender who lost their teeth mostly by periodontaldiseases and caries at the posterior intraoral sites as major ones. Bone densities of type II(mandible) and III(maxilla) were likely to be seen with quantity of type B. Lengths of the implants between 10 and 15 mm and wide platform took the largest part. 2. Survival rates of $Implantium^{(R)}(98.8%)$, $Xive^{(R)}(100%)$ and ITI $TE^{(R)}(100%)$ were high when $Frialit-2^{(R)}$ showed 82%(poor bone density area) or 87.2%(combined with additional therapy). $IMZ^{(R)}$ had lowest cumulative survival(67.5%) and success rate(49.4%) amongst all. 3. Replacement with 2 wide or 3 regular platforms showed no significant differences in survival rate and marginal bone loss atmandibular posterior area. In single restoration of mandibular second molar, 5-year success rate of machined surface $Br{\aa}nemark^{(R)}(70.37%)$ was lower than that of rough surface $ITI^{(R)}$ SLA(100%). 4. Replacement of single tooth in anterior area showed high survival rate of 94.5%. 5. The success rates of $Br{\aa}nemark$ Ti-Unite and ITI SLA at posterior maxilla with poor bone density both showed stable outcomes. 6. 10-year cumulative survival rate of implants with maxillary sinus augmentation by lateral window approach appeared to be 96.60%. Low survival rate(75%) was shown when there were more than two complications combined. Height of grafted bone remained stable above the implant apex. Conclusions : Rough surfaced implants showed stable outcomes in most of the situation including poor bone density and additional therapy combined.