• Title/Summary/Keyword: quantal response model

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GENERALIZED $BARTOSZY\'{N}SKI'S$ VIRUS MODEL

  • Kim, Yong-Dai
    • Journal of the Korean Statistical Society
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    • v.35 no.4
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    • pp.397-407
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    • 2006
  • A new stochastic process is introduced for describing a mechanism of viruses. The process generalizes the $Bartoszy\'{n}ski's$ process ($Bartoszy\'{n}ski$, 1975a, 1975b, 1976) by allowing the stochastic perturbation between consecutive jumps to take into account the persistent infection (the infection without breaking infected cells). It is shown that the new process can be obtained by a weak limit of a sequence of Markov branching processes. Along with the construction of the new process, we study how the stochastic perturbation influences the risk of a symptom in an infected host. For this purpose, the quantal response model and the threshold model are investigated and compared through their induced survival functions.

A comparison of models for the quantal response on tumor incidence data in mixture experiments (계수적 반응을 갖는 종양 억제 혼합물 실험에서 모형 비교)

  • Kim, Jung Il
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.5
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    • pp.1021-1026
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    • 2017
  • Mixture experiments are commonly encountered in many fields including food, chemical and pharmaceutical industries. In mixture experiments, measured response depends on the proportions of the components present in the mixture and not on the amount of the mixture. Statistical analysis of the data from mixture experiments has mainly focused on a continuous response variable. In the example of quantal response data in mixture experiments, however, the tumor incidence data have been analyzed in Chen et al. (1996) to study the effects of 3 dietary components on the expression of mammary gland tumor. In this paper, we compared the logistic regression models with linear predictors such as second degree Scheffe polynomial model, Becker model and Akay model in terms of classification accuracy.

The Confidence Band of $ED_{100p}$ for the Simple Logistic Regression Model

  • Cho, Tae Kyoung;Shin, Mi Young
    • Communications for Statistical Applications and Methods
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    • v.8 no.3
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    • pp.581-588
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    • 2001
  • The $ED_{100p}$ is that value of the dose associated with 100p% response rate in the analysis of quantal response data. Brand, Pinnock, and Jackson (1973) studied the confidence bands of $ED_{100p}$ obtained by solving extremal values algebraically on the ellipsoid confidence region of the parameters in the simple logistic regression model. In this paper, we develope and illustrate a simpler method for obtaining confidence bands for $ED_{100p}$ based on the rectangular confidence region of parameters.

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