• 대한약침학회지
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• 제19권3호
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• pp.259-263
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• 2016

Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Gefitinib is a targeted molecular therapeutic drug used to treat patients with non-small-cell lung cancer (NSCLC). Korean herbal medicines may also have therapeutic efficacy against lung cancer, reduce the side effects associated with chemotherapy, and improve patient quality of life (QOL). This case report describes the effects of a Korean herbal medicine regimen combined with gefitinib in a patient with NSCLC and bone metastasis. The Korean herbal medicine regimen included woohwanggeosa-dan, hwanggibujeong-dan and geonchilgyebok-jeong. The computed tomography (CT) findings showed that following combination treatment, the size of the tumor was markedly decreased without serious adverse events. Moreover, the Eastern Cooperative Oncology Group (ECOG) performance status was improved and cancer-related pain was decreased. These results suggest that a combination of Korean herbal medicines and gefitinib may be an effective therapeutic option for patients with advanced NSCLC and bone metastasis. Further studies are needed to examine the mechanism and the clinical efficacy of Korean herbal medicines against NSCLC.

• 근관절건강학회지
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• 제19권2호
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• pp.197-209
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• 2012

Purpose: This study was aimed to revise Personal Power of Health Care (PPHC) scale which was developed to measure the personal power and competence for health care. Methods: Research phases designed for this study were literature review, scale development, and discussion with experts and pre-test for content validity, and survey for construct validity and reliability. The scale was composed of 25 items with 7 dimensions and tested to 592 adults ranged from 20 to 59 aged living in S and W city. Results: From factor analysis, 7 dimensions were identified and named as follows: Health-perception, Health problem identifying and solving, Socio-economical involvement, Sociocultural relationship, Self-regulation, Spiritual wellbeing, and Health policy participation. The total explained variance was 54.69%. The reliability was .817 of Cronbach's alpha. The PCHC scale was significantly different from gender, religion, education level, monthly income, and presence of family disease, but not different from age and job. Also, there were significant correlations among Health Promotion Lifestyles Profile II, WHO QOL-BREF and self-efficacy. Conclusion: This PCHC scale is reliable and valid to measure personal competence of health care.

• Journal of Korean Biological Nursing Science
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• 제18권4호
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• pp.239-246
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• 2016

Purpose: The purpose of this study was to investigate the effect of denture care skills education program on denture self-care, denture satisfaction and subjective oral status among the elderly. Methods: The research design for this study was a non-equivalent control group quasi-experimental design. Total 61 elderly who visited a seniors center, Seoul, Korea, participated in this study. Participants were 31 elderly for the experimental group and 30 elderly for the control group. The experimental group received a lesson in denture care skills education program which was developed by the researchers. Using a structural questionnaire, the elderly's perception about denture self-care, denture satisfaction and subjective oral status were measured before and after the intervention. Descriptive statistics, independent t-test, chi-square test, and ANCOVA test were performed using SPSS WIN 21.0. Results: The experimental group showed significantly higher scores in denture satisfaction(p<.001), QOL of oral health(<.001), concern for oral health(p=.005), subjective oral health status(p<.001), bad breath(p=.010), oral dryness(p<.001) and number of denture clearing(p<.001). Conclusion: The results suggest that the denture care skills education program for elderly at a senior center was effective. Further work is required to develop more effective denture care skills education programs and an oral health promotion program to improve the health status of the elderly.

• 디지털융복합연구
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• 제11권11호
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• pp.643-650
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• 2013

본 연구는 재가 허약노인을 대상으로 저강도 운동 프로그램이 신체적 기능(악력, 정적균형, 복합적 이동능력), 심리적 기능(우울, 삶의 질)에 미치는 영향을 확인하기 위해 시도된 비동등대조군 전후설계연구이다. 연구결과, 실험군의 악력은 통계적으로 유의하게 증가하였고 복합적 이동능력도 통계적으로 유의하게 감소하였으나 정적 균형은 운동 수행 후 유의한 차이를 나타내지 않았다. 우울은 운동수행 후 유의하게 감소하였으며, 삶의 질은 유의한 차이가 없었다. 결론적으로 재가 허약노인을 위한 저강도 운동 프로그램은 허약노인들의 신체적 기능 향상과 심리적 건강상태를 긍정적으로 변화시키는데 효과적임을 확인할 수 있었다. 본 연구결과를 토대로 재가 허약노인을 위한 저강도 운동 프로그램의 빈도와 강도를 연장하여 그 효과의 지속성을 검정할 수 있는 반복연구를 제언한다.

• 정신신체의학
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• 제27권2호
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• pp.90-100
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• 2019

연구목적 본 연구는 국민건강영양조사 제 7기 1차시기 자료(2016년)를 바탕으로 한국 성인에서 비전형 양상 우울증과 대사증후군 사이의 연관성을 조사하고자 하였다. 방 법 국민건강영양조사 제 7기 1차시기 자료를 이용하였으며 Patient Health Questionnaire (PHQ-9)에서 10점 이상인 277명을 대상으로 하였다. 비전형 양상 우울증은 하루 10시간 이상 수면, 1년간 3 kg 이상의 체중증가, 피로/무기력 3가지 항목 중 2가지 이상을 가질 때로 정의되었다. 우울증 집단을 비전형 양상 유무에 따라 나누어 두 집단의 신체 및 정신적 건강의 차이를 비교하였으며, 대사증후군의 위험도를 분석하였다. 결 과 277명 중 91명이 비전형 양상 우울증을 가지는 것으로 나타났다. 두 집단 사이에 나이, 소득, 성별, 교육에 유의한 차이가 확인되었고, 이러한 변수를 보정한 이후 비전형 양상 우울증 집단은 일반 우울증 집단에 비해 EuroQol-5 dimension (EQ-5D) index는 낮았고(p<0.001), 대사증후군의 유병률은 높은 것으로 나타났다(p=0.035). 비전형 양상 우울증 집단은 일반 우울증 집단에 비해 나이, 성별, 소득, 교육 수준을 보정한 이후에도 대사증후군의 위험도가 높았다(OR=1.923 ; 95% confidence interval : 1.069~3.460). 결 론 비전형 양상 우울증은 일반 우울증에 비해 대사증후군의 위험을 높이고 삶의 질을 감소시키는 것으로 확인되었다.

• 한국안광학회지
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• 제15권2호
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• pp.169-174
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• 2010

목적: 조절이상에 대한 치료가 완료된 어린이에 대해 장기간의 추적 관찰을 함으로써 치료직후에 향상된 눈증상과 조절기능이 지속되는지의 여부를 확인하고자 하였다. 방법: 조절부족이나 조절난이가 있는 조절이상자에 대해 12주 동안 비전세라피 프로그램을 실시한 결과 치료가 성공적으로 이루어진 남여 7명(평균 나이 ${\pm}SD$, $12{\pm}1.41$세)을 대상으로 1년이 경과한 후에 설문지를 사용하여 눈증상을 평가한 후 ${\pm}2.00$ D 플리퍼 렌즈로 단안 및 양안의 조절 용이를 측정하였다. 결과: 치료 프로그램이 완료되고 1년이 경과한 다음 College of Optometrists in Vision Development Quality of Life(COVD-QOL)로 평가한 평균 눈증상은 $15.14{\pm}8.53$점으로 치료 직후의 $11.86{\pm}7.60$점 보다 작은 증가를 보였으나 유의하지 않았다(p=0.176). 그리고 단안(왼쪽 눈) 및 양안의 평균 조절용이 측정값도 각각 $13.86{\pm}3.93cpm$과 $11.14{\pm}3.13cpm$ 으로 치료 직후의 $15.86{\pm}4.14cpm$(p=0.147)과 $13.21{\pm}3.76cpm$(p=0.066)보다 작게 감소하였으나 유의하지는 않았으며, 대상자 모두에서 단안 및 양안 조절용이의 정상값인 7 cpm 이상과 5 cpm 이상을 각각 만족하였다. 결론: 장기간의 추적검사를 통해 치료 프로그램 직후에 향상된 눈증상과 조절기능이 여전히 지속되는 것을 볼 수 있었고, 따라서 조절이상에 대한 비전세라피의 치료효과가 장기적임을 확인하였다.

• 한국산학기술학회논문지
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• 제10권5호
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• pp.1115-1125
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• 2009

본 연구는 초등학생의 안전실천수준과 안전실천 관련요인을 파악하여 초등학생의 안전사고 예방을 위한 프로그램개발에 기초 자료를 제공하기 위하여 시도되었다. 대상자는 549명으로 자가설문지를 이용하였다. 자료분석은 기술적 통계, t-test, ANOVA, Scheffe's test, Pearson correlation coefficient, Stepwise multiple regression을 SPSS 12.0을 이용하여 분석하였다. 안전의식 수준은 3.55점과 안전실천 수준은 2.98점이었으며. 안전실천 수준은 초등학생의 성별, 학년, 친구수, 학교생활적응정도, 학업수준, 성격, 호기심, 안전교육필요성 인식정도, 부모의 안전교육실시 정도, 학교안전교육실시 정도에 통계적으로 유의한 차이가 있었다. 안전실천정도에 영향을 미치는 변수로는 안전의식 수준이 가장 높은 설명력을 나타냈으며, 자아존중감, 부모의 안전교육실시정도가 안전실천 수준을 설명하는 유의한 변수로 모두 28.8%의 설명력을 나타내었다. 안전실천수준에 영향을 미치는 다른 변인을 앞으로 더 규명해야 할 필요가 있다.

• 한방재활의학과학회지
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• 제26권2호
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• pp.105-121
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• 2016

Objectives The purpose of this study was to compare the effects between the degree of herniated intervertebral lumbar disc (HIVD) at L4-5 level and improvement of low back pain treated by Korean Medicine therapy. Methods 567 patients who received inpatient treatment from May 2014 to December 2015 in the Daejeon-Jaseng of Korean Medicine Hospital were divided into 6 groups by the degree of HIVD at L4-5 level confirmed with a Lumbar spine magnetic resonance imaging. All patients received a combination of treatment including acupunture, chuna manual therapy, pharmacopunture, herbal medication. They were compared and analyzed on the basis of improvement between measuring Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), EuroQol-5 Dimension Index (EQ5D Index) as they were hospitalized and as they were discharged. The statistically significance was evaluated by SPSS 23.0 for windows. Results After treatment, Normal stage on Intervertebral Lumbar Disc at L4-5 level group's Numeric Rating Scale (NRS), Oswestry Disability Index (ODI), EuroQol-5 Dimension Index (EQ5D Index) improvement was $1.30{\pm}1.62$, $4.52{\pm}11.82$ and $0.04{\pm}0.11$ respectively. Bulging group's improvement was $3.25{\pm}2.81$, $8.28{\pm}13.02$ and $0.09{\pm}0.17$ respectively. Spinal canal occupying ratio (SOR) less than 20 group's improvement was $2.15{\pm}1.92$, $11.79{\pm}17.81$ and $0.13{\pm}0.23$ respectively. SOR 20 to less than 40 stage group's improvement was $2.13{\pm}1.92$. $10.79{\pm}15.93$ and $0.10{\pm}0.26$ respectively. SOR 40 to less than 60 group's improvement was $2.16{\pm}2.24$, $9.80{\pm}16.62$ and $0.15{\pm}0.25$ respectively. Surgery group's improvement was $2.47{\pm}2.21$, $11.64{\pm}18.53$ and $0.15{\pm}0.27$ respectively (p<0.03). But there was no statistically significance between 6 group's improvement after treatment (p>0.05). Conclusions After inpatient treatment by Korean Medicine therapy, Most patient's pain, disability and Health Related Quality of Life was improved significantly. But there was no statistically correlation between the degree of HIVD at L4-5 level and improvement of low back pain. So We think that future research of higher quality and correct statistics shall be necessary.

• 대한한방부인과학회지
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• 제32권4호
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• pp.116-131
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• 2019

Objectives: The aim of this study was to observe the changes of women's postpartum symptoms, the quality of life and depression scale over the first six weeks after childbirth. Methods: Twenty seven mothers who received Korean medical treatment in the outpatient department treatment (from September 27th, 2017 to January 5th, 2018) were evaluated for Verbal numerical rating scale (VNRS), edema index, EuroQol Visual Analogue Scale (EQ-VAS), and Edinburgh Postnatal Depression Scale (EPDS). Results: There were 17 high risk participants (63.0%) and 10 normal participants (37.0%). The VNRS of edema is the highest in the first week, and the VNRS of joint pain is the highest from the second week to the sixth week in all patients. The Extra Cellular Water/Total Body Water (ECW/TBW) of high risk group significantly decreased from $0.403{\pm}0.011$ to $0.387{\pm}0.006$(p<0.05) in the first 2 weeks. The ECW/TBW of normal group significantly decreased from $0.393{\pm}0.070$ to $0.383{\pm}0.011$ (p<0.05) in the first 2 weeks. The EQ-VAS of high risk group increased from $64.12{\pm}13.941$ to $69.35{\pm}18.155$ (p<0.05) in the first 2 weeks. But this difference was not significant statistically (p=0.234). The EQ-VAS of normal group significantly increased from $62.50{\pm}21.763$ to $74.00{\pm}9.661$ (p<0.05) in the first 2 weeks. The difference of EPDS was not statistically significant between the first week and the sixth week in every participants. Conclusions: VNRS was the highest in edema in the first week, joint pain was the highest from the second week to six week. The edema index of high risk groups was higher than that of the normal group in the first week (p<0.05). The EQ-VAS of normal group significantly increased (p<0.05) in the first 2 weeks but high risk group didn't. In the EPDS, the ratio of nine or more points of high risk group was more than twice than normal group in the first 2 weeks.

• 대한한방부인과학회지
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• 제19권2호
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• pp.240-260
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• 2006

Purpose : The objective of this study is to serve guidelines for the investigation and management of uterine myomas with KM therapies. Methods : English-language articles from PubMed and Korean-language articles from the database of the journal of oriental gynecology were reviewed from 2000 to 2005, using the key words 'uterine myoma', 'uterine leiomyoma', 'fibroid', 'uterine artery embolization', 'endometrial ablation', 'myomectomy', and jagungguenjong(子宮筋腫)'. Results and Limits : The areas of clinical practices considered in formulating this guideline are assessment, KM therapies, medical treatments, myolysis, selective artery occlusion, endometrial ablation and surgical therapies including myomectomy and hysterectomy. Implementation of this guideline would optimize the decision-making process of women with uterine myomas and further investigation or therapy of their KM doctors. But we don't have abundant evidences of clinical trials of uterine myoma treated with KM therapy, though we treat or manage that with every-day clinical practices. Moreover cultural gaps between Korea and other western countries make many differences in the attitude to surgical therapies, especially hysterectomy. So it is very difficult to compare W therapies with other therapies. Moreover it is much difficult to estimate cost-effectiveness and benefit of those therapies in QOL. Conclusions : The majority of uterine myoma is asymptomatic and will not require any intervention or further investigation. But unmarried women who wish to marry and get pregnant want to find safe therapy for their asymptomatic uterine myomas. In that case, most of the patients prefer non-surgical therapy to surgical therapy. So KM herbal medicinal therapy is a good alternative method for those patients. For the symptomatic myomas, hysterectomy offers a definitive solution. However, it is not the best solution for women who wish to preserve their uterus. So KM therapy is a good alternative for them. But the predicted benefits of alternative therapies including KM therapy must be carefully weighed against the Possible risks of these therapies. To improve the quality of life of both women with asymptomatic and symptomatic myomas, selecting and treating patients should be done carefully. Moreover, the effect of KM therapy has to evaluated, comparing the possible situation without treatment and the benefit of constant treatment as a health-care system.