• Journal of Digestive Cancer Research
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• v.2 no.2
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• pp.45-51
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• 2014

Gastric cancer is the second most common cancer and the third leading cause of cancer-related deaths in Korea. Many cases of gastric cancer are detected in the early stages on standard medical examinations; complete surgical and endoscopic resection is the most recommended treatment for early-stage gastric cancer. Nevertheless, many patients have already progressed to advanced gastric cancer (AGC) upon diagnosis, and the prognosis of such patients is very poor. Combination chemotherapy has been shown to produce a better quality of life (QOL) and to increase overall survival in AGC patients. However, approximately 50% of patients do not respond to the current first-line chemotherapy, while most patients who do respond eventually show disease progression. Accordingly, various second-line regimens have been investigated, and active salvage chemotherapy has been shown to improve the QOL and clinical outcomes in select AGS patients who can tolerate it. There is also an increasing need for neoadjuvant therapy for treating gastric cancer; therefore, various clinical trials have been set up to investigate different regimens. Neoadjuvant therapy is currently established as the standard treatment for locally AGC in Europe; it has contributed to lowering the nodal stages and has reduced overall mortality rates. Despite these benefits, many uncertainties remain. Therefore, further prospective, high quality randomized controlled trials for neoadjuvant therapies are needed to clarify their clinical benefits and to establish the most effective treatment strategies for AGC.

• Journal of The Korea Institute of Healthcare Architecture
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• v.29 no.4
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• pp.7-20
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• 2023

Purpose: The main purpose of this paper is to assess a body of research evidence that articulates the impact of physical and environmental factors on behavioral·psychological health and quality of life for the elderly people with dementia who reside in long-term care facilities. This follow-up study of the previous literature review aims to further identify physical and environmental factors, that improve health and quality of life for the elderly people with dementia, published in recent five years and to expand the understanding of clinical outcomes as mechanism that mediate the effect of physical environmental factors on improving behavioral·psychological health and quality of life for the elderly people with dementia. Methods: Comprehensive literature review has been conducted to identify empirical studies that link the design of dementia care facilities to health- and quality of care(QOL)-related outcomes and this follow-up review scrutinized peer-reviewed articles published in recent five years (from January 2018 to December 2022), filling the gap between the previous literature review and the current state of research. Results: The review identified a growing body of literature that articulates environment-related factors that improve behavioral·psychological health and quality of life for the elderly people with dementia living long-term care facilities. Implications: The findings of the review can be translated to design implications and design decisions to promote psychological and behavioral health and quality of life of people with dementia in long-term care facilities.

• Journal of Korean Academy of Nursing
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• v.48 no.6
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• pp.669-678
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• 2018

Purpose: The purpose of this study was to examine the effects of integrated psychoeducational program for distress management of newly diagnosed patients with breast cancer. Methods: A quasi-experimental trial was conducted. The participants consisted of 47 female patients with breast cancer assigned to an intervention group (n=25) and control group (n=22). The intervention group participated in integrated psychoeducational program, consisting of individual face-to-face education and telephone-delivered health-coaching sessions. Data were collected at three time points: pre-intervention (T1), post-intervention (T2), and 6-month follow-up (T3). Study instruments were Distress thermometer, Supportive Care Needs Survey Short Form 34 and Functional Assessment of Cancer Therapy-Breast. Results: Compared with the control group, breast cancer patients in the intervention group reported lower distress and supportive care needs than the control group. The intervention group reported higher quality of life (QOL) overall and higher emotional well-being than the control group. Conclusion: These findings indicate that the integrated psychoeducational program is an effective intervention for reducing distress and supportive care needs and increasing QOL of newly diagnosed patients with breast cancer. Oncology nurses need to provide psychoeducational intervention to support patients with breast cancer in managing their distress and helping them adjust to their life.

• Journal of Sasang Constitutional Medicine
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• v.19 no.2
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• pp.187-194
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• 2007

1. Objectives The incidence of Gallbladder(GB) cancer is increasing through out the world. And the death rate of GB cancer is highest compared with other kinds of cancers. We treated Stage IV GB canter with lung metastasised patient with Sasang constitutional medicine. 2. Methods We fellowed up the changes of Symptoms and QOL. 3. Results The symptoms and quality of lift(QOL) of Stage IV GB cancer with both lung metastasis patient are improved markedly by Sasang constitutional medicine. 4. Conclusions The symptoms of GB cancer with both Lung mets were effectively managed through the constitutional treatment So we report the healing process and result of this patient in this study.

• The Journal of the Society of Stroke on Korean Medicine
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• v.19 no.1
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• pp.31-40
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• 2018

■ Objectives The purpose of this case study is to report the effectiveness of Korean medicine in the treatment of chronic hyperhidrosis. ■ Methods The patient was diagnosed as a Soeumin Mang-yang Syndrome, and treated with Korean medical treatment such as Sungyangikgibuja-tang and acupuncture treatment. The severity of symptom was assessed using Numerical Rating Scale (NRS) and follow-up of Hyperhidrosis Quality of Life Index (HidroQOL) ■ Results After treatment, the severity of hyperhidrosis was decreased from NRS 10 to NRS 2, HidroQOL score was also decreased from 32 to 19. ■ Conclusion Korean medical treatment for hyperhidrosis was effective in decreasing the NRS and HidroQOL score. The results suggest that Korean medical combined treatment including Sungyangikgibuja-tang and acupuncture treatment can be a effective option for treating hyperhidrosis.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.63-74
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• 2013

Objectives : The purpose of this study is to examine the effects of 3 day Forests healing programs for cognitive improvement, which consists of helpful contents of Korean medicine. Methods : This study examined the effects of forests healing for mild cognitive impairment patients, who visited a Korean medicine hospital neuropsychiatry clinic for outpatients. The Forests healing programs for cognitive improvement was run with 24 participants, in which 9 of them quit in the middle of the program, so excluded in data analysis. The Forests healing programs for cognitive improvement was consisted of 3 day helpful Korean medicine contents. The primary outcome measurement was a Computerized Neurocognitive Test (CNT), which measured the cognitive functions with computer programs. Results : The results of this study showed that CNT scores were not significantly changed after 3 day forests healing. General psychological states, including depression, anxiety, and anger, were also checked. Among them, depressive mood significantly improved. Quality of life (QOL) was also enhanced after 3 day program. These results indicate that the 3 day Forests healing programs for cognitive improvement was effective for depressive mood and QOL of mild cognitive impairment patients, but not enough for cognitive functions directly. Conclusions : The 3 day Forests healing programs for cognitive improvement were shown to be an effective intervention in improving some aspects of mild cognitive impairment patients, including depressive mood, and QOL. We suggest that repeated participation of this program can enhance cognitive function of mild cognitive impairment patients.

• PNF and Movement
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• v.21 no.3
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• pp.345-356
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• 2023

Purpose: The aim of this study was to investigate the effects of physical therapy combined with a virtual reality (VR) game on pain, quality of life (QOL), engagement, and knee function in post-knee-surgery patients. Methods: Twenty-four patients who had undergone knee surgery four weeks or more before the study were recruited. Two withdrew from the study during the four-week experimental period, and a total of 22 patients were included in the final analysis. Routine physical therapy consisting of electrostimulation (10 min.) and therapeutic massage (10 min.) was the base intervention for all groups. The experimental group (n = 10) was additionally exposed to a VR game intervention, while the control group (n = 12) underwent an intervention involving similar motions as the experimental intervention but with no VR. The intervention for the experimental group used the game Rig Fit Adventure on Nintendo switch. Both groups underwent their respective interventions 3 times a week (35 min. per session) for 4 weeks. Pain was assessed using the numeric rating scale (NRS), and QOL was assessed using the EuroQol five-dimensional five-level questionnaire (EQ-5D-5L). Engagement was assessed using the Korea flow state scale (K-FSS). Finally, knee movement and function were assessed based on knee flexion and extension, range of motion (ROM), and Western Ontario and McMaster Universities Arthritis Index (WOMAC). Results: After the four-week physical therapy, both groups showed significant reductions in pain (on the NRS), increased knee ROM (flexion), better WOMAC scores, and increased EQ-5D-5L scores (p < 0.05), with the experimental group showing significantly better improvements in EQ-5D-5L and K-FSS scores (p < 0.05). Conclusion: The results of this study confirm that a VR-game-integrated intervention is effective for improving pain, QOL, engagement, and knee function in post-knee surgery patients and that VR-game-integrated interventions could be therapeutic alternatives for patients bedridden for prolonged periods with little motivation for rehabilitation.

• The Journal of the Korea Contents Association
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• v.14 no.7
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• pp.356-366
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• 2014

The purpose of this study was to identify the impact of the mood state on the quality of life (QOL) of the female breast cancer survivor. The study was cross-sectional survey. This study was conducted from September 10th to September 20th, 2013. The subjects were 120 breast cancer survivors in Seoul city in Korea. The obtained data were analyzed by SPSS/WIN 21.0 program. The mean score of mood state was 39.20 and the mean score of the quality of life was 83.59. The levels of mood state and the quality of life were negatively correlated. The significant factors influencing quality of life were vigor and anger of the mood state, religion that explained 39.1% of the variance. The results suggests that appropriate support service should be provided to improve the quality of life after nurses evaluate breast cancer survivor's mood states and identify the symptoms of mood disturbances.

• The Journal of the Korea Contents Association
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• v.18 no.6
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• pp.652-666
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• 2018

The purpose of this study was to investigate systematic review and meta-analysisto identify exercise intervention effect applied to patients who underwent lung resection with lung cancer. A total of 1,322 publications were searched from 1990 to 2016 through domestic and foreign electronic databases, and the final 13 publications were selected through literature selection process. Finally, eight RCT (randomized controlled trial) and five NRCT (non-randomized controlled trial) were identified, including 925 participants. The results of the meta-analysis of the effect sizes of the intervention on the outcome variables showed that the health-related quality of life EORTC QOL-C13/30 (the European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire) (MD-0.50 95 % CI -0.83-0.18) and SF-36 PCS (the Medical Outcomes 36-Item Short Form Health Survey PCS) (MD 0.75, 95 % CI 0.41-1.10) in the intervention group were significantly higher than the control group. The results of this study suggest that exercise interventions can potentially improve the quality of life of patients who underwent lung resection with lung cancer.

• 대한예방의학회:학술대회논문집
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• 1997.10b
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• pp.187-188
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• 1997