• Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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• v.29 no.1
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• pp.9-13
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• 2018

Postoperative airway aspiration is not uncommon in patients with head and neck cancer. Airway aspiration has serious consequences, such as swallowing disorders, nutrition-related health problem, or reducing the quality of life due to maintenance of tracheal or nasogastric tubes. The postoperative oropharyngeal defect due to the surgery may interfere with normal swallowing reflex, or the laryngeal dysfunction caused by radiation therapy may cause severe airway aspiration, which may lead to complications such as dyspnea and pneumonia. Complete removal of the disease is also important in the treatment of head and neck cancer, but it is necessary to select a method to avoid and predict the occurrence of airway aspiration according to the treatment method. The most important factor to prevent airway aspiration after surgery is to preserve the proper volume of the oropharynx and to preserve at least one of the cricoarytenoid joint function. It is also the most effective way to reduce additional complications by seeking appropriate surgical treatment according to airway aspiration status. The purpose of this study is to review the operative methods that can induce airway aspiration and consider the prevention and treatment strategy through review of the literature.

• Smart Structures and Systems
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• v.9 no.1
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• pp.1-20
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• 2012

In bridge engineering, maintenance strategies and thus budgetary demands are highly influenced by construction type and quality of design. Nowadays bridge owners and planners tend to include life-cycle cost analyses in their decision processes regarding the overall design trying to optimize structural reliability and durability within financial constraints. Smart permanent and short term monitoring can reduce the associated risk of new design concepts by observing the performance of structural components during prescribed time periods. The objectives of this paper are the discussion and analysis of influence line or influence field approaches in terms of (a) an efficient incorporation of monitoring information in the structural performance assessment, (b) an efficient characterization of performance indicators for the assessment of structures, (c) the ability of optimizing the positions of sensors of a monitoring system, and (d) the ability of checking the robustness of the monitoring systems applied to a structure. The proposed influence line- model correction approach has been applied to an integrative monitoring system that has been installed for the performance assessment of an existing three-span jointless bridge.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.2
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• pp.283-300
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• 2004

Currently commercial dry sows are housed in individual stalls and subject to restricted feeding. These sows often show stereotypic behaviours which increase their maintenance energy requirement. Group housing is desirable to improve animal welfare and public perception. However, under restricted feeding systems, group-housed dry sows are also aggressive. The feed intake of these sows is variable, depending on their social rank, which results in different milk production and variable piglet performance. These problems can be solved by ad libitum feeding systems, but the large capacity of intake by dry sows will not allow this feeding system to be practical as high feeding level during pregnancy can reduce reproduction performance of sows. Current research indicates that feeding high fibre diets to dry sows enables sows to be fed ad libitum, but the effect of dietary fibre on feed intake and nutrient utilisation is dependent on the quality of fibre sources. Most research has focused on sugar beet pulp, straw, lucerne meal and by-products, but there is a need to identify and evaluate some widely available and cheap fibre materials and feed grains for developing the best strategy to control nutrient intake of dry sows while feeding ad libitum.

• Journal of mucopolysaccharidosis and rare diseases
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• v.1 no.2
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• pp.35-39
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• 2015

Sleep problems occur frequently among patients with Prader-Willi syndrome (PWS). The most common problem is excessive daytime sleepiness (EDS) that are closely related to of sleep-related breathing disorder (SRBD) such as obstructive sleep apnea (OSA) and congenital hypoventilation syndrome. Obesity, craniofacial dysmorphism and muscular hypotonia of patients with PWS may increase the risk of SRBD. Sleep apneas can interrupt the continuity of sleep, and these disruptions result in a decrease in both the quality and quantity of sleep. In addition to SRBD, other sleep disorders have been reported, such as hypersomnia, a primary abnormality of the rapid eye movement (REM) sleep and narcolepsy traits at sleep onset REM sleep. Patients with PWS have intrinsic abnormalities of sleep-wake cycles due to hypothalamic dysfunction. The treatment of EDS and other sleep disorders in PWS are similar to standard treatments. Correction of sleep hygiene such as sufficient amount of sleep, maintenance of regular sleep-wake rhythm, and planned naps are important. After comprehensive evaluation of sleep disturbances, CPAP or surgery should be recommended for treatment of SRBD. Remaining EDS or narcolepsy-like syndrome are controlled by stimulant medication. Bright light therapy might be beneficial for disturbed circadian sleep-wake rhythm caused by hypothalamic dysfunction.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.1752-1759
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• 2007

In the new Seoul-Busan high speed railroad construction specially city center passage roadbed establishment is recommended the staibility for the existing subway tunnel segments of Busan subway line No. 1 and No.2. regarding the appearance condition, a quality condition and the durability of the objective facility site exact inspection, and it evaluates the numerical analysis which uses MIDAS GTS it leads and there is the objective of the place where the stability of the objective facility and this tunnel it investigates. To immediacy of the on-the-spot inspection result whole facility it is a condition where the reinforcement which is simple not to be hindrance is necessary, 2nd Line case it is a condition which transfer is good but the general defect and the damage which occur from the tunnel of NATM type were confirmed part. While roadbed establishment constructing that the continuous maintenance is necessary, it is judged. The result of 1st, 2nd Line maximum sinkage, unequal sinkage and the lining stress of numerical analysis are within permission and the damage degree is appearing with the fact that the degree it will can disregard it is slight. But it enforces necessary Pre-grouting in order to minimize an actual tunnel face conduct and when the tunnel is excavated it is judged with the fact that necessary to minimize the outflow possibility.

• Proceedings of the KSR Conference
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• 2007.05a
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• pp.1129-1137
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• 2007

50kg NSI PCT(Prestress Concrete Timber, sleeper) is developed for the purpose of low maintenance cost, Extend life cycle, Track stability, Friendly Environment, Good running quality. In this study, as a part of research which is to make renovated NSI turnout, the main objective of this study is the optimization of PC sleeper's section, the number of PS tension wire. For this purpose, the finite element analysis was conducted to evaluate the serviceability and the safety of NSI PC sleeper developed.

• Journal of Korean Society of Rural Planning
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• v.19 no.3
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• pp.107-116
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• 2013

In this study, it provides the diagnostic index for the rural landscape formation. For the development of diagnostic index, this study first analyzed documents and papers on the landscape formation. Landscape types are also classified by their function and then landscape index was developed by AHP method. Classification system was categorized as three steps: 2 items for 1st step, 10 items for 2nd step, and 20 items(criteria) for 3rd step. In the survey of weighting values with AHP method, the analysis result for the first step showed that rural village landscape is more important than landscape around the village by approximately 20%. In the second step, residence is rated as the most important, followed by village tree planting, and then farmland around the rural villages, greenery, and water environment. In the third step, the feng shui is rated as the most important, followed by tree planting, village forest, culture, and history. While vehicle maintenance, village alleys and pedestrian facilities are rated lower. In index of the around the village, weighting value for index of the farm land and skyline has the highest value. While species richness, water quality and water resources were rated relatively low. In the future, the rural landscapes diagnosis index will be applied to measure the level of the rural villages landscapes and it is expected to propose political support for the landscapes formation.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.16 no.9 s.114
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• pp.964-970
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• 2006

Micro gas turbine(MGT) has received attention recently as small-scale distributed power sources. With characteristics such as their small size, lightweight, low maintenance cost and minimal vibrations during operation, they are expected to become widespread in a wide range of ' applications, including residential and small-scale industrial use. It is very easier to start-up and stop the MGT system which is the friendly environmental power system has just below the 9ppm NOx emmission and good quality of noise level. The exhaust heat emitted by the MGT is in the form of about $300^{\circ}C$ clean exhaust gas. The exhaust gas is suitable for absorption chiller/heater system. 1 has researched performance characteristics of the 60 kW class MGT-absorption chiller-heater system in the local condition. Variations of heat recovery from exhaust gas has measured according to micro gas turbine output of 15, 30, 45, 60kW. From those results, the performance of the MGT-absorption chiller/heater system has been evaluated.

• Biomolecules & Therapeutics
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• v.26 no.1
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• pp.4-9
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• 2018

Cancer metabolism as a field of research was founded almost 100 years ago by Otto Warburg, who described the propensity for cancers to convert glucose to lactate despite the presence of oxygen, which in yeast diminishes glycolytic metabolism known as the Pasteur effect. In the past 20 years, the resurgence of interest in cancer metabolism provided significant insights into processes involved in maintenance metabolism of non-proliferating cells and proliferative metabolism, which is regulated by proto-oncogenes and tumor suppressors in normal proliferating cells. In cancer cells, depending on the driving oncogenic event, metabolism is re-wired for nutrient import, redox homeostasis, protein quality control, and biosynthesis to support cell growth and division. In general, resting cells rely on oxidative metabolism, while proliferating cells rewire metabolism toward glycolysis, which favors many biosynthetic pathways for proliferation. Oncogenes such as MYC, BRAF, KRAS, and PI3K have been documented to rewire metabolism in favor of proliferation. These cell intrinsic mechanisms, however, are insufficient to drive tumorigenesis because immune surveillance continuously seeks to destroy neo-antigenic tumor cells. In this regard, evasion of cancer cells from immunity involves checkpoints that blunt cytotoxic T cells, which are also attenuated by the metabolic tumor microenvironment, which is rich in immuno-modulating metabolites such as lactate, 2-hydroxyglutarate, kynurenine, and the proton (low pH). As such, a full understanding of tumor metabolism requires an appreciation of the convergence of cancer cell intrinsic metabolism and that of the tumor microenvironment including stromal and immune cells.

• Food Science of Animal Resources
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• v.37 no.6
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• pp.833-839
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• 2017

In this study, the physicochemical and sensory properties of Gouda cheese supplemented with microcapsules of chili pepper extract were evaluated. Microcapsules of pepper extract were prepared by coacervation technique using gum acacia-gelatin wall and chili pepper oil core. Changes in pH, lactic acid bacteria (LAB) population, and free amino acid (FAA) content after supplementation of Gouda cheese with chili pepper capsules were monitored during ripening. Texture and sensory characteristics of the Gouda cheese ripened for 6 months were evaluated. The supplementation of pepper extract microcapsules (0.5% or 1%, w/w) did not influence the pH values and LAB content of the Gouda cheese (p<0.05) during the ripening period. While the content of total FAA increased with the ripening process in all the cheese groups (p<0.05), no significant difference (p<0.05) in the content of total FAA was observed among the sample groups at each time point. The addition of pepper extract microcapsules (1%, w/w) to Gouda cheese significantly decreased hardness (p<0.05) and negatively affected sensory attributes in terms of taste and texture (p<0.05). The results demonstrated that supplementation with 0.5% pepper extract microcapsules could provide additional bioactive ingredients, along with maintenance of the quality of Gouda cheese.