• Journal of Veterinary Science
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• 제24권2호
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• pp.32.1-32.10
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• 2023

Background: The association between vitamin D and canine keratoconjunctivitis sicca (KCS) has not been investigated in dogs. Objectives: To investigate the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with Schirmer tear test 1 (STT-1) and tear film breakup time (TFBUT) in dogs. Methods: Sixty-one clinically healthy, client-owned dogs were enrolled. STT-1 and TFBUT were measured in 122 (61dogs) and 82 (41 dogs out of total 61 dogs) eyes, respectively. Serum 25(OH)D concentrations were evaluated by quantitative chemiluminescent immunoassay. The dogs were classified into 6 groups according to the evaluations (STT-1: group 1, normal [≥ 15 mm/min] in both eyes; group 2, normal in one eye and abnormal [< 15 mm/min] in the fellow eye; group 3, abnormal in both eyes; TFBUT: group 4, normal [≥ 20 sec] in both eyes; group 5, normal in one eye and abnormal [< 20 sec] in the fellow eye; group 6, abnormal in both eyes). Results: STT-1 was positively correlated with TFBUT (p < 0.001). Among the STT-1 groups, the mean serum 25(OH)D concentration in group 1 was significantly higher than in groups 2 and 3 with positive correlation (p < 0.001). However, there were no significant differences among the TFBUT groups 4, 5, and 6. Conclusions: In dogs, it was found that serum 25(OH)D concentrations had a greater effect on quantitative KCS than qualitative KCS. Therefore, it is considered that measurement of serum 25(OH)D concentration could be included in the diagnostic tests in canine quantitative KCS patients.

• 산업진흥연구
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• 제8권3호
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• pp.87-93
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• 2023

본 연구는 코로나19 팬데믹 이후 우리나라의 노인복지를 위한 교회 공동체 역할에 대한 연구이다. 연구의 목적은, 팬데믹 이후 노인복지에 대한 교회 공동체 기관의 역할을 수행함으로써 복지 수혜자인 노인들의 삶이 보다 더 안정적이고 행복한 삶이 될 수 있게 하고, 정부와 지자체, 지역사회 단체, 교회와의 네트워크를 통하여 효율적인 노인복지가 되게 하는데 있다. 연구방법은, 질적 연구로써 각 교회의 담임목사와 노인복지 담당목사와의 심층면접을 통하여 얻어낸 내용의 면접기록지를 1차 자료로 사용하였고, 1년간의 노인복지 사업 결과물을 2차 자료로 사용하여 조사·분석하였다. 연구 결과, 노인들이 코로나19 팬데믹의 힘든 환경, 상황 가운데서도 최소한의 복지 혜택을 받을 수 있었다. 자원과 지원의 한계에도 불구하고 노인들은 교회공동체에 많이 의존하고 있었고, 관계망 속에서의 안정감과 만족도도 높음으로 나타났다. 노인복지에 있어서 교회 공동체의 역할을 활용하여 우리나라 노인복지 발전에 기여하고자 하는 것이 본 연구의 목적이자 의의이다.

• Restorative Dentistry and Endodontics
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• 제47권3호
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• pp.27.1-27.14
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• 2022

Objectives: This systematic review and meta-analysis aimed to assess the association of cigarette smoking with the prevalence of post-endodontic apical periodontitis in humans. Materials and Methods: We searched through PubMed/Medline, Web of Science, and Scopus from inception to December 2020. Risk of bias was performed by using the Newcastle-Ottawa Scale for cross-sectional, cohort, and case-control studies. We performed the statistical analysis in Review Manager 5.3 (RevMan 5.3). Results: 6 studies met the inclusion criteria for qualitative and quantitative synthesis. Statistical analysis of these studies suggests that there were no differences in the prevalence of post endodontic apical periodontitis (AP) when comparing non-smokers vs smoker subjects regarding patients (odds ratio [OR], 0.68; 95% confidence interval [CI], 0.31-1.49; I2 = 58%) and teeth (OR, 1.71; 95% CI, 0.99-2.93; I2 = 72%). Conclusions: Our findings suggest that there was no association between cigarette smoking and post-endodontic apical periodontitis, as we did not find statistical differences in the prevalence of post-endodontic AP when comparing non-smokers vs smoker subjects. Therefore, smoking should not be considered a risk factor associated with endodontic failure.

• 대한한의학회지
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• 제44권3호
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• pp.189-200
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• 2023

Objectives: The purpose of this study is to analyze the current state of quantitative literature evidence for the prescription of 56 herbal medicines covered by health insurance that have been studied in Korea for the past 30 years, to evaluate the reliability of the evidence, and to find out the research direction of herbal medicine prescription in the future. Methods: 56 kinds of herbal medicine prescriptions were searched in domestic literature search databases OASIS, DBpia, and overseas PubMed, classified into chemistry, toxicity, cells, animals, clinical cases, and clinical trial studies, and built into an EBM pyramid structure. Results: When classified according to research contents, there were 61 cases (7.5%) of physicochemical analysis to identify constituent substances, 80 cases (9.8%) of toxicity evaluation, and 672 cases (82.7%) of efficacy evaluation. The efficacy evidence was classified according to the evidence-based medical pyramid structure: 196 cell trials (29.1%), 372 animal trials (55.4%), 89 case and case reporting series (13.3%), 7 comparative case studies (1.1%), and 8 randomized control clinical trials (1.2%). In the pyramid composition, the basis for the validity of 56 kinds of herbal medicines prescribed was 568 cases (84.5%) in cell and animal units, which could not be said to be highly reliable. There was no relationship between the ranking of quantitative literature evidence for herbal medicine prescriptions and the ranking of salary administration. Conclusions: In an era that continues to require scientific evidence for herbal medicine, traditional herbal medicine should secure the basis for safety validity even for the 10th most frequent prescription among 56 herbal medicine prescriptions for consumers. In particular, traditional herbal medicine should increase the quantitative and qualitative level of case reports on related herbal medicine prescriptions, focusing on each clinical society, and move toward comparative case studies and randomized clinical trial so that traditional herbal medicine is positioned as Evidence-based medicine.

• 농촌계획
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• 제30권1호
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• pp.43-55
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• 2024

The purpose of this study is to examine residents' perspectives on factors contributing to rural decline, including population decrease and landscape degradation, with the goal of proposing strategies to revitalize rural spaces in response to these challenges. After exploring rural decline issues in Jinan, a questionnaire was developed based on a review of existing research. Following this, participants were selected, and Focus Group Interviews(FGI) were conducted. Through the analysis of the findings, strategies for local revitalization were suggested in four sectors. Based on the research findings, there is a need to reassess public transportation and vacant property projects. On the social front, preventing the misuse of rural relocation policies and enhancing residential environments through spatial clarity are essential. Environmentally, clustering renewable energy and livestock facilities and attracting educational facilities are necessary to minimize disruption to rural landscapes. From a governance perspective, fostering entrepreneurship in rural tourism and business models utilizing the local landscape is crucial for an increase in regional visits. This study holds significance by emphasizing the practical situation of rural decline, steering away from resource-centric or business-focused policies. It underscores the potential usefulness of integrating this understanding into detailed planning within policies aimed at tackling rural decline.

• Journal of Information Science Theory and Practice
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• 제12권1호
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• pp.1-20
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• 2024

This research aims to study and confirm enabling factors affecting the knowledge transfer and business process of community enterprise groups in Pattani province, Thailand. Key informants were community enterprise entrepreneurs; 30 people were selected purposively with criteria. This study used a mixed-methods approach and conducted semi-structured interviews to collect data. Qualitative data were analyzed using content analysis and classification, while quantitative data were analyzed using descriptive statistics with frequency, percentage, mean, and standard deviation. Moreover, inferential statistics chi-square value, Phi Cramer's V, and multiple regression analysis with the R program for statistical computing were employed to analyze the relationship between the variables, test the research hypothesis, and create forecasting equations. The research results revealed that the overview of enabling factors had a very high relationship (Cramer's V=0.965). Regarding community enterprise, it was found that enabling factors related to the knowledge transfer and business process consisted of four factors: regulations and administrative guidelines, business plan, reinforcement, and brainstorming. Reinforcement was the factor with the highest degree of correlation (Cramer's V=0.873) and predictor of influence on the knowledge transfer and business process (R₂=0.670, p<0.05). This study's findings can lead to the developing of guidelines for promoting community enterprises properly and timely. These guidelines are expected to be used to develop knowledge about business models for community enterprises, which will help to improve their competency and competitiveness.

• Journal of Veterinary Science
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• 제25권2호
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• pp.28.1-28.11
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• 2024

Background: Porcine circovirus type 2 (PCV2) infection is ubiquitous around the world. Diagnosis of the porcine circovirus-associated disease requires clinic-pathological elements together with the quantification of viral loads. Furthermore, given pig farms in regions lacking access to sufficient laboratory equipment, developing diagnostic devices with high accuracy, accessibility, and affordability is a necessity. Objectives: This study aims to investigate two newly developed diagnostic tools that may satisfy these criteria. Methods: We collected 250 specimens, including 170 PCV2-positive and 80 PCV2-negative samples. The standard diagnosis and cycle threshold (Ct) values were determined by quantitative polymerase chain reaction (qPCR). Then, two point-of-care (POC) diagnostic platforms, convective polymerase chain reaction (cPCR, qualitative assay: positive or negative results are shown) and EZtargex (quantitative assay: Ct values are shown), were examined and analyzed. Results: The sensitivity and specificity of cPCR were 88.23% and 100%, respectively; the sensitivity and specificity of EZtargex were 87.65% and 100%, respectively. These assays also showed excellent concordance compared with the qPCR assay (κ = 0.828 for cPCR and κ = 0.820 for EZtargex). The statistical analysis showed a great diagnostic power of the EZtargex assay to discriminate between samples with different levels of positivity. Conclusions: The two point-of-care diagnostic platforms are accurate, rapid, convenient and require little training for PCV2 diagnosis. These POC platforms can discriminate viral loads to predict the clinical status of the animals. The current study provided evidence that these diagnostics were applicable with high sensitivity and specificity in the diagnosis of PCV2 infection in the field.

• 한국식품과학회지
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• 제36권4호
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• pp.677-682
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• 2004

유전자변형(GM)작물의 안전에 대한 논란은 우리나라를 포함한 많은 나라들이 GM 식품의 강제적 표시제를 도입하게 하였다. 본 연구의 목적은 어떤 수준의 열, 압력, 및 산 처리가 정성 PCR과 LEST 방법의 검출 한계 아래까지 GM 콩 혼합물의 DNA나 단백질을 파괴할 수 있는지를 조사하는 것이었다. 결과는 열처리나 고압열처리는 처리 시간에 따라서 도입유전자의 검출이 되지 않을 정도로 DNA와 단백질을 작은 절편들로 파괴함을 보여주었다. 흥미 있는 점은, 가공식품을 위한 LFST의 검출력은 약하게 가공처리된 콩에서 증가하였다. DNA 및 단백질 검출법 모두 $121^{\circ}C$, 1.5기압에서 20분 동안 처리한 후 GM 혼입물의 검출력을 거의 상실하였다. 본 연구의 결과는 시중에 유통되는 어떤 종류의 가공식품이 GM 작물 식품으로 표시되어야 할지를 결정하는데 유용할 것이다.

• 정보화정책
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• 제25권4호
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• pp.3-36
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• 2018

본 연구에서는 ICT가 융합된 미래 교육에 대한 다양한 논의를 교육의 목표, 내용, 방법, 평가의 측면에서 고찰하여 ICT 활용 교육의 동향과 전망을 제시하였다. 첫째, ICT 교육의 목표는 다양한 정체성을 바탕으로 역동적인 사회 참여를 가능케하는 디지털 시민성의 구성이다. 디지털 시민성의 확립을 위해서 ICT 교육은 '평생 학습자', '정보생산자이자 소비자', '지역적 세계적 시민' 등을 학습자의 미래 핵심 역량으로 인식하고 있다. 둘째, 교육내용 측면에서 중요성이 부각되고 있는 것은 SW 교육이다. 이에 실제 수업 적용을 위한 프로그램 개발 연구나 효과성 검증 연구가 활발하게 진행되고 있다. 그러나 교육환경 개선과 함께 교사 역량을 강화할 수 있는 제도적 지원, 교과교육과의 통합 운영 역량 강화 등이 뒷받침되지 않는다면 미래 사회를 대비하기 위한 교육내용으로서의 적절성이 반감될 것이다. 셋째, 교육 방법으로서 플립러닝이나 증강현실 등 다양한 ICT가 실제 수업에 적용되고 있다. 각 교과별로 가장 활발하게 연구가 진행되는 분야로서, 해당 기술을 활용한 수업의 설계, 수업의 효과성을 보여주는 연구들은 기존 교육방법을 보완하고 ICT 교육 현장의 질적 변화를 이끄는 데 토대가 될 것이다. 넷째, 평가와 관련된 논의는 컴퓨터 기반 평가에 집중되어 있다. ICT를 활용한 평가는 학습자의 특성 및 수준을 정확하게 파악하고 적절한 방법의 교수-학습 과정을 전반적으로 안내하는 평가의 본질에 더욱 효과적으로 기여할 것이다. 이상의 ICT 교육에 관한 종합적인 검토와 함께 교육 불평등의 관점에서 평가한 ICT 교육의 가능성을 논의하였다.

• 한국컴퓨터정보학회논문지
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• 제26권1호
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• pp.239-251
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• 2021

중국의 전통의학은 자연경험학적으로 병을 치료하고 건강을 증진시켰으나, 19세기 말부터 선진국 중심으로 자연요법에 관심이 커지면서 아로마요법을 연구하게 되었다. 본 연구는 아로마요법과 관련된 선행연구들을 검색하여 증상에 따른 에센셜오일과 신체 적용부위, 사용방법, 사용기간 등을 종합적으로 분석하였다. 연구내용은 중국연구재단 검색엔진인 CNKI(www.cnki.com)과 WANFANG DATE(www.wanfang.com)의 플랫폼에서 방향요법(芳香?法)(아로마요법)과 관련된 2000년~2019년까지의 학술지 및 학회지를 검색 및 선별하였다. 선별된 논문은 5단계 질적평가와 전문가의 평가를 통해 최종 30편의 연구논문을 분석하였다. 자료는 Excel 2013 Program을 이용하여 빈도와 백분율(%)을 구하고, 도표로 나타내었다. 아로마요법 동향분석결과 30편 모두 의학계에서 연구한 논문이다. 증상별로는 불안, 초초, 불안적 증상이 13편으로 가장 많았고, 에센셜오일 종류로는 라벤더오일, 버가못 오일이 높았고, 적용부위와 방법은 코를 이용한 흡입법으로 나타났다. 증상에 따른 에센셜오일은 초조증상/우울증/산통/수면장애/편두통/긴장/수술 후/구토증 통증/피로에서 모두 라벤더가 가장 높고, 부정적 감정증상은 오렌지, 메스꺼움은 레몬, 진저, 페파민트 오일로 나타났다. 이의 결과 아로마요법이 간호미용 및 의료미용에서 환자를 대상으로 신체 적용부위, 사용방법, 사용기간이 도출되었지만, 의료인들이 간단한 적용방법으로 흡입법과 극소적인 마사지가 높았다. 그러나 진통, 산통, 긴장 등은 단기간에 효능을 볼 수 있으나, 정신신경학적인 부분은 기간을 길게 적용한다는 표준적인 근거를 제공하였다.