• 치과방사선
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• 제3권1호
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• pp.35-38
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• 1973

The authors have interpreted one patient's full mJuth intra-oral films, oblique- lateral film of the left mandible and orthopantomograph which revealed 6 radicular and 1 residual cysts. As a results of interpretation of these serial films, we have drawn following conclusions: 1. Radicular cyst arose from the cell rests contained in an apical granuloma which was sequel to advanced pulpitis due to dental caries. 2. Residual cyst was developed from remaining cell rests after the extraction of a tooth with such a radicular cyst or apical dental granuloma. 3. Cyst grew in size by absorption of fluid into cystic cavity due to difference in osmotic pressure between the cystic fluid and adjacent tissue fluid.

• The Korean Journal of Pain
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• 제26권4호
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• pp.347-355
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• 2013

Pain and pain control are important to the dental profession because the general perception of the public is that dental treatment and pain go hand in hand. Successful dental treatment requires that the source of pain be detected. If the origin of pain is not found, inappropriate dental care and, ultimately, extraction may result. Pain experienced before, during, or after endodontic therapy is a serious concern to both patients and endodontists, and the variability of discomfort presents a challenge in terms of diagnostic methods, endodontic therapy, and endodontic knowledge. This review will help clinicians understand the basic neurophysiology of pulpal pain and other painful conditions of the dental pulp that are not well understood.

• Journal of Dental Anesthesia and Pain Medicine
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• 제18권6호
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• pp.319-332
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• 2018

The objective of this review was to investigate the efficacy of dental local anesthetics, as it is well known among clinicians that local anesthesia may be challenging in some circumstances. Therefore, the focus of this review was on the efficacy of the products used in dental local anesthesia. In a Pubmed database literature search conducted, a total of 8646 articles were found to be related to dental local anesthetics. After having applied the inclusion criteria (human research, performed in the last 10 years, written in English language, and focus on dental local anesthetics) and having assessed the quality of the papers, 30 were deemed eligible for inclusion in this review. The conclusion of this review is that none of the dental local anesthetic amides provide 100% anesthesia. The problem appears to be more pronounced when mandibular teeth are attempted to be anaesthetized and especially if there is irreversible pulpitis involved. The authors conclude that this finding suggest exploration of more efficient techniques to administer dental local anesthesia, especially in the mandible, to establish a 100% efficacy, is needed.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권1호
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• pp.54-54
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• 2023

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권1호
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• pp.57-57
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• 2023

• Restorative Dentistry and Endodontics
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• 제30권5호
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• pp.409-422
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• 2005

치아우식증 및 치주질환에 이환 여부와 치근단 병소의 존재 유무에 따라 급성 치수염 또는 급성 치근단 농양이라고 진단된 17개 치아의 치관부 치수를 제거하고, 치근에 존재하는 괴사된 치수 및 농양부위의 샘플을 채취하여, 혐기성 상태에서 세균을 배양하고, 이들을 16S rDNA 클로닝 및 핵산염기서열결정법으로 종 수준에서 동정하였다. 그 결과 17개의 치근관감염 병소에서 모두 71개의 세균 군락이 자라났으며, 그 중 계대 배양을 통해서 적응하여 자라난 것이 56 균주였다. 치아우식증에 의한 치근관 감염 병소와 치아우식증이 아닌 다른 원인에 의한 치근관 감염 병소에서 검출되는 세균은 서로 다른 양상을 보였다. 즉, 치아우식증에 의한 치아의 치근관 감염 병소에서 연쇄상구균들이 $72.7\%$(8/11)로 가장 많은 빈도로 검출되었다. 반면에 치아우식증이 없는 치아의 치근관 감염 병소에서는 Actinomyces속의 균주들이 $66.7\%$로 가장 높은 빈도로 검출되었다. 치근단 병소가 있는 경우의 치근관 감염 병소에는 대체로 혐기성 세균인 Clostridia 아문, Bacteroides 문, Fusobacteria 문의 균주들이 검출되었지만, 치근단 병소가 없는 치아에서는 검출되지 않았다 반면에 치근단 병소가 없는 치근관 병소에서는 연쇄상구균($60\%$)과 Actinomyces속($50\%$)의 균주들이 높은 빈도로 검출되었다. 본 연구에서는 아직까지 종 수준에서 동정되지 않은 2 균주(ChDC B639 및 ChDC B631)의 Actinomyces속에 속하는 균주가 분리되었다. 이상의 결과를 종합할 때, 세균배양법에 의한 치수 및 치근단 감염 병소에서는 다양한 세균이 검출되었으며, 이는 치근관 감염이 여러 세균에 의해 발병 및 진행된다는 기존의 연구 결과와 동일함을 알 수 있었다. 또한 본 연구 결과 분리 동정된 균주들은 치근관질환과 이와 관련된 세균간의 역학조사에 중요한 자원으로 이용될 수 있을 것으로 생각된다.

• 치과방사선
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• 제27권2호
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• pp.15-25
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• 1997

This study was performed to prepare the quantitative method of judging the sensitive prognosis of chronic apical periodontitis as early as possible. The subjects were 25 cases with periapical radiolucencies of which were treated with endodontic treatment. Serial radiographs were taken by standardized method longitudinally. The density slice function of digital radiographic system were employed for quantitative and longitudinal assessment of the radiolucent area and the condensing osteitis simultaneously. Obtained results were as follows: 1. The amount of bone repair after endodontic treatment could be detected quantitatively by the density slice function of digital radiographic system. 2. Within the 6-week period after root canal filling, the prognosis could be evaluated by assessment both radiolucent area and condensing osteitis on digital radiographic system. 3. The pattern of bone repair showed peripheral type in most cases from the 6th week after root canal filling. 4. In longitudinal change, bone repair showed two patterns; the succeeding reduction of radiolucent area showing the increase of condensing osteitis in size till 6th week and following by static state or reduction tendency and the reduction following the initial increase of both areas. 5. Cases with pulpitis by trauma showed initial increase of condensing osteitis at 2nd week, marked reduction of radiolucent area and condensing osteitis at 6th week, and approximately normal bone state at 8th week after root canal filling.

• Journal of Dental Anesthesia and Pain Medicine
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• 제16권1호
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• pp.1-8
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• 2016

Most dental pain is caused by an organic problem such as dental caries, periodontitis, pulpitis, or trauma. Diagnosis and treatment of these symptoms are relatively straightforward. However, patients often also complain of abnormal dental pain that has a non-dental origin, whose diagnosis is challenging. Such abnormal dental pain can be categorized on the basis of its cause as referred pain, neuromodulatory pain, and neuropathic pain. When it is difficult to diagnose a patient's dental pain, these potential alternate causes should be considered. In this clinical review, we have presented a case of referred pain from the digastric muscle (Patient 1), of pulpectomized (Patient 2), and of pulpectomized pain (Patient 3) to illustrate referred, neuromodulatory, and neuropathic pain, respectively. The Patient 1 was advised muscle stretching and gentle massage of the trigger points, as well as pain relief using a nonsteroidal anti-inflammatory and the tricyclic antidepressant amitriptyline. The pain in Patient 2 was relieved completely by the tricyclic antidepressant amitriptyline. In Patient 3, the pain was controlled using either a continuous drip infusion of adenosine triphosphate or intravenous Mg2+ and lidocaine administered every 2 weeks. In each case of abnormal dental pain, the patient's diagnostic chart was used (Fig.2 and 3). Pain was satisfactorily relieved in all cases.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제33권1호
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• pp.20-27
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• 2007

Eugenol is commonly used in dentistry for the sedation of toothache, pulpitis, and dental hyperalgesia. This study was performed to investigate the apoptotic effect of eugenol to human osteosarcoma (HOS) cells and the potential use of this compound in osteosarcoma cells. Eugenol showed the apoptotic effect in HOS cells in dose- and time-dependent manner. Fragmentation and condensation of DNA were showed by TUNEL assay, Hemacolor stain and Hoechst stain. In the DNA electrophoresis analysis, cells showed DNA degradation characteristic of apoptosis with a ladder pattern of DNA fragments. Apoptosis-related factors were analyzed by western blotting. Cells treated with eugenol showed caspase-3, PARP, lamin A and DFF-45 cleavage. Eugenol treatment induced caspase-3 cleavage and activation. Cleavages of PARP, DFF-45 and lamin A were accompanied with activation of caspase triggered by eugenol in HOS cells. Though this study needs more investigations, these results suggest that eugenol induce apoptosis via caspase dependent pathway in HOS cells and eugenol may constitute a potential antitumor compound against osteosarcoma cells.

• Restorative Dentistry and Endodontics
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• 제42권2호
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• pp.140-145
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• 2017

Objectives: The aim of this randomized, controlled, prospective clinical study was to evaluate patients' intraoperative discomfort during root canal preparations in which either multi-file rotary (Mtwo) or single-file reciprocating (Reciproc) systems were used. Materials and Methods: Fifty-five adult patients, aged between 25 and 69 years old, with irreversible pulpitis or pulp necrosis participated in this study. Either the mesiobuccal or the distobuccal canals for maxillary molars and either the mesiobuccal or the mesiolingual canals for mandibular molars were randomly chosen to be instrumented with Mtwo multi-file rotary or Reciproc single-file reciprocating systems. Immediately after each canal instrumentation under anesthesia, patient discomfort was assessed using a 1 - 10 visual analog scale (VAS), ranging from 'least possible discomfort' (1) to 'greatest possible discomfort' (10). The Wilcoxon signed-rank test was used to determine significant differences at p < 0.05. Results: Little intraoperative discomfort was found in all cases. No statistically significant differences in intraoperative discomfort between the 2 systems were found (p = 0.660). Conclusions: Root canal preparation with multi-file rotary or single-file reciprocating systems had similar and minimal effects on patients' intraoperative discomfort.