• Title/Summary/Keyword: pseudo 3-D

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Characteristics of the Inhibitory Action of Protease Inhibitors on the Glucose-6-phosphate Transporter

  • Choi, Joon-Sig;Shin, Jeong-Sook;Choi, Hong-Sug;Park, Jong-Sang
    • BMB Reports
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    • v.30 no.2
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    • pp.157-161
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    • 1997
  • The present paper reports characteristics and specificity of the inhibitory action of $N^{\alpha}-tosyl-L-lysine-chloromethyl\;ketone$ (TLCK) and $N^{\alpha}-tosyl-L-phenylalanine-chloromethyl\;ketone$ (TPCK) on the glucose6-phosphate transporter of rat liver microsomes. The TLCK-induced inhibition was pH dependent. The inhibition constants for TPCK were determined by following pseudo-Lst order reaction mechanism. The inhibition was protected by preincubation with excess amount of glucose-6-phosphate. The results proved that (a) TLCK inactivates the microsomal glucose-6-phosphate transporter, (b) the inhibition results from the modification of sulfhydryl groups of the transporter.

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Synthesis and Molecular Structure of Tetrahomodioxa p-Phenylcalix[4]arene Tetra Ester Derivative in 1,4-Alternate Conformation

  • 노관현;박영자;최은주
    • Bulletin of the Korean Chemical Society
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    • v.20 no.8
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    • pp.905-909
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    • 1999
  • Reaction of tetrahomodioxa p-phenylcalix[4]arene with ethyl bromoacetate and potassium carbonate in ace-tone leads to the title tetra ester derivative, 7,13,21,27-tetra-phenyl-29,30,31,32 -tetrakis(ethoxycarbonyl)meth-oxy-2,3,16,17-tetrahomo-3,17-dioxacalix[4]arene, its structure was determined by NMR spectra as 1,4-alternate conformation. The molecular structure has been solved by X-ray diffraction methods. The molecule has a conformation with pseudo center of symmetry. The benzene ring A is up, ring C is down, B and D rings are flat with respect to the plane of the macrocyclic ring.

Design and Implementation of Photovoltaic Power Conditioning System using a Current-based Maximum Power Point Tracking

  • Lee, Sang-Hoey;Kim, Jae-Eon;Cha, Han-Ju
    • Journal of Electrical Engineering and Technology
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    • v.5 no.4
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    • pp.606-613
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    • 2010
  • This paper proposes a novel current-based maximum power point tracking (CMPPT) method for a single-phase photovoltaic power conditioning system (PV PCS) by using a modified incremental conductance method. The CMPPT method simplifies the entire control structure of the power conditioning system and uses an inherent current source characteristic of solar cell arrays. Therefore, it exhibits robust and fast response under a rapidly changing environmental condition. Digital phase locked loop technique using an all-pass filter is also introduced to detect the phase of grid voltage, as well as the peak voltage. Controllers of dc/dc boost converter, dc-link voltage, and dc/ac inverter are designed for coordinated operation. Furthermore, a current control using a pseudo synchronous d-q transformation is employed for grid current control with unity power factor. A 3 kW prototype PV PCS is built, and its experimental results are given to verify the effectiveness of the proposed control schemes.

Hydraulic Eroperty of Groundwater Flow Controlled by Vertical Geologic Structure and its field Example (수직 지질구조에 의해서 지배되는 암반지하수 유동의 수리적 성질과 그 예)

  • 함세영;김형찬;임정웅
    • Journal of the Korean Society of Groundwater Environment
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    • v.5 no.2
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    • pp.101-109
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    • 1998
  • Hydraulic property of fissured aquifers often depends on geologic structure which acts main channel of groundwater flow. We treated theories of linear flow related to vertical geologic structure. Then, we analyzed the result of two pumping tests conducted in Okmyeong-ri area (Kyeongbook province) using fractal model and found hydraulic characteristic of the fissured aquifer in this area. According to the pump test analyses, groundwater flow around the holes (pumping well D9; observation wells C3 and D7) of test 1 is linear. and is controlled by vertical geologic structure with infinite length and infinitesimally small width. On the other hand, around the hole D10 (pumping well) of test 2, groundwater flow is pseudo-radial (n=1.9) or radial (n=2). Thus, the characteristic of fractured aquifer often shows variable groundwater flow spatially and temporally.

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Differentiated Human Embryonic Stem Cells Enhance the In vitro and In vivo Developmental Potential of Mouse Preimplantation Embryos

  • Kim, Eun-Young;Lee, Keum-Sil;Park, Se-Pill
    • Asian-Australasian Journal of Animal Sciences
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    • v.23 no.9
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    • pp.1152-1158
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    • 2010
  • In differentiating human embryonic stem (d-hES) cells there are a number of types of cells which may secrete various nutrients and helpful materials for pre-implantation embryonic development. This study examined whether the d-hES could function as a feeder cell in vitro to support mouse embryonic development. By RT-PCR analysis, the d-hES cells revealed high expression of three germ-layered differentiation markers while having markedly reduced expression of stem cell markers. Also, in d-hES cells, LIF expression in embryo implantation-related material was confirmed at a similar level to undifferentiated ES cells. When mouse 2PN embryos were cultured in control M16 medium, co-culture control CR1aa medium or co-cultured with d-hES cells, their blastocyst development rate at embryonic day 4 (83.9%) were significantly better in the d-hES cell group than in the CR1aa group (66.0%), while not better than in the M16 group (90.7%)(p<0.05). However, at embryonic days 5 and 6, embryo hatching and hatched-out rates of the dhES cell group (53.6 and 48.2%, respectively) were superior to those of the M16 group (40.7 and 40.7%, respectively). At embryonic day 4, blastocysts of the d-hES cell group were transferred into pseudo-pregnant recipients, and pregnancy rate (75.0%) was very high compared to the other groups (M16, 57.1%; CR1aa, 37.5%). In addition, embryo implantation (55.9%) and live fetus rate (38.2%) of the d-hES cell group were also better than those of the other groups (M16, 36.7 and 18.3%, respectively; CR1aa, 23.2 and 8.7%, respectively). These results demonstrated that d-hES cells can be used as a feeder cell for enhancing in vitro and in vivo developmental potential of mouse pre-implantation embryos.

Remagnetization of the Cretaceous Sedimentary Rocks in the Yeongdong Basin (영동분지에 분포하는 백악기 퇴적암류의 재자화)

  • Doh, Seong-Jae;Cho, Yun-Young;Suk, Dongwoo
    • Economic and Environmental Geology
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    • v.29 no.2
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    • pp.193-209
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    • 1996
  • Paleomagnetic and rock-magnetic data have been obtained from the Cretaceous rocks (Yeongdong Group, volcanic rock, and intrusive rocks) which are exposed in the Yeongdong Basin. The characteristic remanent directions of these rocks, which are mainly carried by magnetite and hematite of single and pseudo-single domain sizes, are normally magnetized (Yeongdong Group: $D/I=29.6/59.0^{\circ}C$, k=75.7, ${\alpha}_{95}=3.3^{\circ}$, N=25 sites, paleopole at $198.0^{\circ}E$, $66.4^{\circ}N$, K=46.1, $A_{95}=4.3^{\circ}$; volcanic rock: $D/I=352.8/44.1^{\circ}$, k=44.2, ${\alpha}_{95}=18.8^{\circ}$, N=3 sites, paleopole at $340.0^{\circ}E$, $78.8^{\circ}N$, $K=49.8^{\circ}E$, $A_{95}=17.6^{\circ}$X>; intrusive rocks: $D/I=358.4/51.9^{\circ}C$, k=20.0, ${\alpha}_{95}=13.8^{\circ}$, N=7 sites, paleopole at $338.1^{\circ}E$, $86.8^{\circ}N$, K=13.5, $A_{95}=17.1^{\circ}$). The stepwise unfolding of the characteristic remanent magnetization (ChRM) of the Yeongdong Group reveals that a maximum value of k is observed at 60% of unfolding with $D/I=13.0/58.6^{\circ}$ (k=124.62, ${\alpha}_{95}2.6^{\circ}$) indicating that the ChRM was aquired during ti1ting of the strata. This remagnetized ChRM in the sedimentary strata is due to acquisition of geomagnetic field direction at the time of formation of authigenic magnetic minerals, although it is not totally ruled out that the formation of authigenic magnetic minerals was affected indirect1y by the elevated temperature originated from the volcanic and intrusive rocks which intruded between Late Cretaceous and Early Tertiary.

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Structural and Electrical Transport Properties of CuCr1-xNixO2 by Pulsed Laser Deposition

  • Kim, Se-Yun;Seong, Sang-Yun;Chu, Man;Jo, Gwang-Min;Hong, Hyo-Gi;Lee, Jun-Hyeong;Kim, Jeong-Ju;Heo, Yeong-U
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.08a
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    • pp.210-210
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    • 2010
  • ABO2 형태를 가진 delafossite 구조 산화물은 p-type 투명전도체 소재로 유명하다. Delafossite 구조가 p-type 투명전도체에 적합한 결정적인 이유는 밴드갭이 넓고 공유결합에 유리하기 때문이다. 투명전도체는 가시광선의 흡수가 없도록 band gap을 넓히는 것이 우선인데 이러한 band gap이 넓은 구조가 delafossite이다. 또한 delafossite 구조는 구조적으로 각각의 산화물 이온들이 유사 사면체 배위(pseudo-tetrahedral coordination)을 갖는다. 이러한 사면체 배위결합구조에서 산소이온은 비결합면이 없기 때문에 더욱더 공유결합성을 향상시킬 것으로 생각된다. 여기서 A는 +1가 cation, B은 +3가 cation으로 구성되어 있다. A자리에는 1가 원소인 팔라듐, 플래티늄, 은, 구리 등을 가질 수 있고. B자리에 3가 원소이면서도 크기가 알루미늄보다는 크고 란타늄보다는 작은 금속이 들어갈 수 있다. Delafossite 구조는 상온에서 2종류의 polytype (상온에서 Rhombohedaral 구조와 hexagonal 구조)이 존재하며 이들은 각각 3R(Rm) 및2H (P63/mmc)의 결정 구조를 가지고 있다. CuCrO2는 일반적으로 3R결정구조를 가지는 것으로 알려져 있다. delafossite 구조는 전기적 이방성을 띄고 있는데 c-축 방향으로의 전기적 특성이 a-축 방향으로의 전기적 특성보다 약 1000배 높은 물성을 띈다고 한다. 이는 c-축 방향의 원자 위치 때문인데 CuCrO2의 경우 Cu-O-Cr-O-Cu로서 3d-2p-3d-2p-3d 궤도를 가지기 때문인 것으로 알려져 있다.[ref] 반면 c-축으로 에피성장된 박막의 경우 +3가 이온이 위치한 layer에서 hole hopping에 의해 캐리어가 전도된다고 알려져 있기도 하다. 본 연구에서는 PLD를 이용하여 c-plane 사파이어 기판위에 성장된 delafossite구조인 CuCrO2박막의 특성을 알아보았다. p-type 특성을 위하여 CuCrO2에 Ni를 첨가하였으며 그에 따른 구조적 전기적 특성을 조사하였다. 성장온도와 도핑농도를 변화시켜 특성을 연구하였다. 결정구조적 특성과 전기적 특성을 분석하려 한다.

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Development of Rapid Hardening Backfill Material for Reducing Ground Subsidence (지반함몰 저감을 위한 속경형 하수관거 뒤채움재료 개발)

  • Ryu, Yong-Sun;Han, Jin-Gyu;Chae, Woo-Ri;Koo, Ja-Sul;Lee, Dae-Young
    • Journal of the Korean Geosynthetics Society
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    • v.14 no.3
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    • pp.13-20
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    • 2015
  • Inappropriate backfill material and poor compaction cause the damage to sewer and ground settlement. To deal with such problem, flowable backfill material has attracted attention recently. A basic study was conducted in a bid to obtain optimum mixing ratio of backfill material with the characteristics of rapid hardening, pseudo-plasticity, flowability and anti washout ability and enhance the cost efficiency of backfill material. Through the test of optimal mixing ratio of rapid hardening, evaluation of optimal mixing ratio of backfill material was conducted. As a result, required performance as well as cost efficiency could be achieved by adjusting plasticizer even in case of increasing W/M of the paste of rapid hardening to 100%.

Synthesis Of Asymmetric One-Dimensional 5-Neighbor Linear MLCA (비대칭 1차원 5-이웃 선형 MLCA의 합성)

  • Choi, Un-Sook
    • The Journal of the Korea institute of electronic communication sciences
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    • v.17 no.2
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    • pp.333-342
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    • 2022
  • Cellular Automata (CA) is a discrete and abstract computational model that is being applied in various fields. Applicable as an excellent pseudo-random sequence generator, CA has recently developed into a basic element of cryptographic systems. Several studies on CA-based stream ciphers have been conducted and it has been observed that the encryption strength increases when the radius of a CA's neighbor is increased when appropriate CA rules are used. In this paper, among CAs that can be applied as a one-dimensional pseudo-random number sequence generator (PRNG), one-dimensional 5-neighbor CAs are classified according to the connection state of their neighbors, and the ignition relationship of the characteristic polynomial is obtained. Also this paper propose a synthesis algorithm for an asymmetric 1-D linear 5-neighbor MLCA in which the radius of the neighbor is increased by 2 using the one-dimensional 3-neighbor 90/150 CA state transition matrix.

DEVELOPMENT OF AN UNSTRUCTURED HYBRID MESH FLOW SOLVER FOR 3-D STEADY/UNSTEADY INCOMPRESSIBLE FLOW SIMULATIONS (삼차원 정상/비정상 비압축성 유동해석을 위한 비정렬 혼합격자계 기반의 유동해석 코드 개발)

  • Jung, Mun-Seung;Kwon, Oh-Joon
    • Journal of computational fluids engineering
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    • v.13 no.2
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    • pp.27-41
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    • 2008
  • An unstructured hybrid mesh flow solver has been developed for the simulation of three-dimensional steady and unsteady incompressible flow fields. The incompressible Navier-Stokes equations with an artificial compressibility method were discretized by using a node-based finite-volume method. For the unsteady time-accurate computation, a dual-time stepping method was adopted to satisfy a divergence-free flow field at each physical time step. An implicit time integration method with local time stepping was implemented to accelerate the convergence in the pseudo-time sub-iteration procedure. The one-equation Spalart-Allmaras turbulence model has been adopted to solve high-Reynolds number flow fields. The flow solver was parallelized to minimize the CPU time and to overcome the computational overhead. This method has been applied to calculate steady and unsteady flow fields around submarine configurations and a 3-D infinite cylinder. Validations were made by comparing the predicted results with those of experiments or other numerical results. It was demonstrated that the present method is efficient and robust for the prediction of steady and unsteady incompressible flow fields.